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Open AccessArticle

Controlling Shapes in a Coaxial Flow Focusing Microfluidic Device: Experiments and Theory

1
Department of Electronic and Biomedical Engineering, University of Barcelona, Marti i Franques, 1, 08028 Barcelona, Spain
2
Department of Condensed Matter Physics, University of Barcelona, Marti i Franques, 1, 08028 Barcelona, Spain
*
Author to whom correspondence should be addressed.
Micromachines 2020, 11(1), 85; https://doi.org/10.3390/mi11010085
Received: 29 November 2019 / Revised: 27 December 2019 / Accepted: 7 January 2020 / Published: 13 January 2020
(This article belongs to the Section A:Physics)
A coaxial flow focusing PDMS (polydimethylsiloxane) microfluidic device has been designed and manufactured by soft lithography in order to experimentally study a miscible inner flow. We studied a coaxially focused inner flow (formed by an aqueous fluorescein solution) which was fully isolated from all microchannel surfaces by an additional water outer flow. Different flow rates were used to produce a variety of flow ratios and a 3D reconstruction of the cross-section was performed using confocal microscope images. The results showed an elliptical section of the coaxially focused inner flow that changes in shape depending on the flow rate ratio applied. We have also developed a mathematical model that allows us to predict and control the geometry of the coaxially focused inner flow. View Full-Text
Keywords: microfluidic; coaxial; interface; focusing; orientation; confocal microfluidic; coaxial; interface; focusing; orientation; confocal
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Rodriguez-Trujillo, R.; Kim-Im, Y.-H.; Hernandez-Machado, A. Controlling Shapes in a Coaxial Flow Focusing Microfluidic Device: Experiments and Theory. Micromachines 2020, 11, 85.

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