Micromachines, Volume 10, Issue 10 (October 2019) – 88 articles
Cover Story (view full-size image):
Circulating tumor cells are important clinical markers for both early diagnosis and prognosis of cancer. However, it remains challenging to capture circulating tumor cells with high efficiency and purity. Here, we developed a novel microfluid chip with a hierarchically structured surface by integrating a microwavy structure and nanoparticles. We show that such a hierarchical surface increases both capture efficiency and purity by several folds compared to a surface with only a single-scale pattern. View this paper
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