Integration of Hierarchical Micro-/Nanostructures in a Microfluidic Chip for Efficient and Selective Isolation of Rare Tumor Cells
Abstract
:1. Introduction
2. Method and Materials
2.1. Fabrication and Surface Functionalization of the Hierarchical CTC Chip
2.2. Preparation of Cell Samplesand Cell Capture
3. Results and Discussions
3.1. Working Mechanism
3.2. Characterization of Hierarchical Micro/nanostructures
3.3. Cancer Cell Capture
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Wang, S.; Cho, Y.; Cheng, X.; Yang, S.; Liu, Y.; Liu, Y. Integration of Hierarchical Micro-/Nanostructures in a Microfluidic Chip for Efficient and Selective Isolation of Rare Tumor Cells. Micromachines 2019, 10, 698. https://doi.org/10.3390/mi10100698
Wang S, Cho Y, Cheng X, Yang S, Liu Y, Liu Y. Integration of Hierarchical Micro-/Nanostructures in a Microfluidic Chip for Efficient and Selective Isolation of Rare Tumor Cells. Micromachines. 2019; 10(10):698. https://doi.org/10.3390/mi10100698
Chicago/Turabian StyleWang, Shunqiang, Younghyun Cho, Xuanhong Cheng, Shu Yang, Yi Liu, and Yaling Liu. 2019. "Integration of Hierarchical Micro-/Nanostructures in a Microfluidic Chip for Efficient and Selective Isolation of Rare Tumor Cells" Micromachines 10, no. 10: 698. https://doi.org/10.3390/mi10100698