Journal Menu► ▼ Journal Menu
Journal Browser► ▼ Journal Browser
Special Issue "Microfluidics-based Liquid Biopsies"
Deadline for manuscript submissions: 15 January 2020.
Interests: microfluidics; cancer; liquid biopsy; cancer biomarkers; droplet-based microfluidics; 3D tissues; cancer model; circulating tumor cells; circulating biomarkers
Liquid biopsies provide a minimally invasive screening option for the analysis of tumor-specific material in biological fluids, such as the peripheral blood samples of patients. The analysis of circulating tumor cells or the tracking of tumor specific genetic or epigenetic alterations in cell-free circulating nucleic acids can provide real-time information, allowing for the detection of early-stage cancer, monitoring disease progression, predicting a response to drugs, and providing personalized treatment options. Thanks to recent technological advances, the field of liquid biopsies has now passed the proof-of-concept period and is beginning to find application in clinics. With the ability to manipulate fluids inside the architectures with dimensions that are comparable to the size of single cells, and with the ability to perform highly sensitive and quantitative analyses, microfluidic technologies have shown great potential for providing the tools needed for the handling of liquid biopsies.
With this Special Issue, we aim to tackle the recent, innovative microfluidics-based tools and the detection techniques for the handling and analysis of circulating tumor cells, exosomes, circulating tumor DNA, or circulating RNA, and we provide a detailed discussion regarding the potential opportunities for microfluidics-based approaches in cancer diagnostics.
Dr. Valérie Taly
Dr. Deniz Pekin
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- liquid biopsy
- circulating tumor DNA
- circulating RNA
- circulating tumor cells
- colorectal cancer
- liquid biopsy