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Micromachines, Volume 10, Issue 9

2019 September - 74 articles

Cover Story: A modified mathematical model based on concentration distribution was applied to tumor growth in both static and dynamic platforms. Apoptosis and necrosis mechanisms were considered as the main inhibitory factors in the model, while tumor growth rate and nutrient consumption rate were modified in both quiescent and proliferative zones. Such modifications could better predict the experimental results of tumor growth. Finally, tumor growth kinetics in both U-shaped barriers and microwell structures were compared. View this paper
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Articles (74)

  • Article
  • Open Access
21 Citations
6,696 Views
12 Pages

19 September 2019

This protocol provides insights into the rapid, low-cost, and largescale fabrication of polymer microfluidic chips containing three-dimensional microstructures used in point-of-care devices for applications such as detection of pathogens via molecula...

  • Article
  • Open Access
12 Citations
4,861 Views
13 Pages

19 September 2019

In this paper, in view of low grinding efficiency and poor ground surface quality of sapphire glass, the coarse diamond grinding wheel dressed by dry impulse electrical discharge was proposed to perform efficient and precise grinding machining of sap...

  • Article
  • Open Access
30 Citations
5,041 Views
13 Pages

Spider Web-Like Phononic Crystals for Piezoelectric MEMS Resonators to Reduce Acoustic Energy Dissipation

  • Fei-Hong Bao,
  • Xue-Qian Wu,
  • Xin Zhou,
  • Qi-Die Wu,
  • Xiao-Sheng Zhang and
  • Jing-Fu Bao

19 September 2019

Phononic crystals (PnC) are a remarkable example of acoustic metamaterials with superior wave attenuation mechanisms for piezoelectric micro-electro-mechanical systems (MEMS) resonators to reduce the energy dissipation. Herein, a spider web-like PnC...

  • Article
  • Open Access
9 Citations
3,601 Views
11 Pages

Fabrication and Study on Magnetic-Optical Properties of Ni-Doped ZnO Nanorod Arrays

  • Wei Wang,
  • Shoulong Hui,
  • Fuchun Zhang,
  • Xiaoyang Wang,
  • Shuili Zhang,
  • Junfeng Yan and
  • Weihu Zhang

18 September 2019

Zn1-xNixO nanorod arrays were prepared on Si substrates by magnetron sputtering and hydrothermal methods at 100 °C. We studied the effects of doped concentration and hydrothermal growth conditions on the crystal structure, morphology, photolumine...

  • Article
  • Open Access
19 Citations
8,011 Views
12 Pages

18 September 2019

The needle-type piezoelectric jetting dispenser is widely applied in the microelectronics packaging field, and it is important to control the droplet size to ensure that the droplet jetting process is successful. In this study, we analyzed the influe...

  • Editorial
  • Open Access
1 Citations
2,657 Views
3 Pages

17 September 2019

The Micro-Nano Science and Technology Division of the JSME (Japan Society of Mechanical Engineers) promotes academic activities to pioneer novel research topics on microscopic mechanics [...]

  • Article
  • Open Access
40 Citations
5,713 Views
21 Pages

17 September 2019

It is crucial to control the temperature of solar cells for enhancing efficiency with the increasing power intensity of multiple photovoltaic systems. In order to improve the heat transfer efficiency, a microchannel heat sink (MCHS) with V-ribs using...

  • Communication
  • Open Access
13 Citations
3,886 Views
10 Pages

17 September 2019

Detecting the depth and size of debonding in composite structures is essential for assessing structural safety as it can weaken the structure possibly leading to a failure. As composite materials are used in various fields up to date including aircra...

  • Review
  • Open Access
193 Citations
17,173 Views
18 Pages

Nanostructures for Light Trapping in Thin Film Solar Cells

  • Amalraj Peter Amalathas and
  • Maan M Alkaisi

17 September 2019

Thin film solar cells are one of the important candidates utilized to reduce the cost of photovoltaic production by minimizing the usage of active materials. However, low light absorption due to low absorption coefficient and/or insufficient active l...

  • Article
  • Open Access
18 Citations
5,867 Views
13 Pages

16 September 2019

Monocrystalline silicon is an important semiconductor material and occupies a large part of the market demand. However, as a hard-brittle material, monocrystalline silicon is extremely prone to happen edge chipping during sawing processing. The edge...

  • Article
  • Open Access
14 Citations
4,462 Views
13 Pages

An Integrated Portable Multiplex Microchip Device for Fingerprinting Chemical Warfare Agents

  • Karolina Petkovic,
  • Anthony Swallow,
  • Robert Stewart,
  • Yuan Gao,
  • Sheng Li,
  • Fiona Glenn,
  • Januar Gotama,
  • Mel Dell’Olio,
  • Michael Best and
  • Yonggang Zhu
  • + 2 authors

16 September 2019

The rapid and reliable detection of chemical and biological agents in the field is important for many applications such as national security, environmental monitoring, infectious diseases screening, and so on. Current commercially available devices m...

  • Feature Paper
  • Article
  • Open Access
6 Citations
3,777 Views
12 Pages

Integration of Horizontal and Vertical Microfluidic Modules for Core-Shell Droplet Generation and Chemical Application

  • Dong Hyun Yoon,
  • Yoshito Nozaki,
  • Daiki Tanaka,
  • Tetsushi Sekiguchi and
  • Shuichi Shoji

15 September 2019

This paper presents a method for utilizing three-dimensional microfluidic channels fully to realize multiple functions in a single device. The final device structure was achieved by combining three independent modules that consisted of horizontal and...

  • Article
  • Open Access
5 Citations
3,965 Views
11 Pages

15 September 2019

This paper describes the development and application of microfluidic cord-based analytical devices (µCADs) in two enzyme-linked immunosorbent assays (ELISAs) and glucose assay. In this study, biotinylated goat anti-mouse immunoglobulin (IgG) an...

  • Article
  • Open Access
33 Citations
8,758 Views
8 Pages

High-Precision Propagation-Loss Measurement of Single-Mode Optical Waveguides on Lithium Niobate on Insulator

  • Jintian Lin,
  • Junxia Zhou,
  • Rongbo Wu,
  • Min Wang,
  • Zhiwei Fang,
  • Wei Chu,
  • Jianhao Zhang,
  • Lingling Qiao and
  • Ya Cheng

15 September 2019

We demonstrate the fabrication of single-mode optical waveguides on lithium niobate on an insulator (LNOI) by optical patterning combined with chemomechanical polishing. The fabricated LNOI waveguides had a nearly symmetric mode profile of ~2.5 &micr...

  • Article
  • Open Access
4 Citations
5,274 Views
6 Pages

14 September 2019

Hybrid quantum dot light-emitting diodes (QLEDs) with no buffer layer were developed to achieve white emission using red quantum dots by spin-coating, and blue phosphorescent organic molecules by thermal evaporation. These unique bichromatic devices...

  • Article
  • Open Access
3 Citations
3,240 Views
13 Pages

14 September 2019

A vertical Hall device is an important component of 3D Hall sensors, used for detecting magnetic fields parallel to the sensor surface. The Hall devices described in existing research still have problems, such as large offset voltage and low sensitiv...

  • Article
  • Open Access
8 Citations
5,473 Views
17 Pages

14 September 2019

With the advent of ultrafast lasers, new manufacturing techniques have come into existence. In micromachining, the use of femtosecond lasers not only offers the possibility for three-dimensional monolithic fabrication inside a single optically transp...

  • Feature Paper
  • Article
  • Open Access
7 Citations
3,904 Views
16 Pages

Manipulation of Magnetic Beads with Thin Film Microelectromagnet Traps

  • Vania Silverio,
  • Miguel Amaral,
  • João Gaspar,
  • Susana Cardoso and
  • Paulo P. Freitas

13 September 2019

Integration of point-of-care assays can be facilitated with the use of actuated magnetic beads (MB) to perform testing in less expensive settings to enable the delivery of cost-effective care. In this paper we present six different designs of planar...

  • Article
  • Open Access
27 Citations
3,703 Views
12 Pages

13 September 2019

The large random errors in Micro-Electro-Mechanical System (MEMS) gyros are one of the major factors that affect the precision of inertial navigation systems. Based on the indoor inertial navigation system, an improved wavelet threshold de-noising me...

  • Feature Paper
  • Article
  • Open Access
26 Citations
4,147 Views
10 Pages

Sustainable Fully Printed UV Sensors on Cork Using Zinc Oxide/Ethylcellulose Inks

  • Joana Figueira,
  • Cristina Gaspar,
  • José Tiago Carvalho,
  • Joana Loureiro,
  • Elvira Fortunato,
  • Rodrigo Martins and
  • Luís Pereira

12 September 2019

Low-cost and large-scale production techniques for flexible electronics have evolved greatly in recent years, having great impact in applications such as wearable technology and the internet of things. In this work, we demonstrate fully screen-printe...

  • Article
  • Open Access
20 Citations
4,154 Views
10 Pages

Microfluidic-Based Mechanical Phenotyping of Androgen-Sensitive and Non-sensitive Prostate Cancer Cells Lines

  • Na Liu,
  • Panpan Du,
  • Xiaoxiao Xiao,
  • Yuanyuan Liu,
  • Yan Peng,
  • Chen Yang and
  • Tao Yue

12 September 2019

Cell mechanical properties have been identified to characterize cells pathologic states. Here, we report our work on high-throughput mechanical phenotyping of androgen-sensitive and non-sensitive human prostate cancer cell lines based on a morphologi...

  • Correction
  • Open Access
4 Citations
2,471 Views
1 Page

12 September 2019

The authors would like to indicate the following financial support they received to the Funding Section of their published paper [...]

  • Feature Paper
  • Article
  • Open Access
9 Citations
4,602 Views
12 Pages

Metallization of Organically Modified Ceramics for Microfluidic Electrochemical Assays

  • Ashkan Bonabi,
  • Sari Tähkä,
  • Elisa Ollikainen,
  • Ville Jokinen and
  • Tiina Sikanen

12 September 2019

Organically modified ceramic polymers (ORMOCERs) have attracted substantial interest in biomicrofluidic applications owing to their inherent biocompatibility and high optical transparency even in the near-ultraviolet (UV) range. However, the processe...

  • Communication
  • Open Access
26 Citations
6,934 Views
12 Pages

12 September 2019

Biofilms exist in the natural world and applied to many industries. However, due to the variety of characteristics caused by their complex components, biofilms can also lead to membrane fouling and recurrent infections which pose threats to human hea...

  • Article
  • Open Access
19 Citations
3,968 Views
11 Pages

11 September 2019

Metal-oxide (MOX) gas sensors are widely used for gas concentration estimation and gas identification due to their low cost, high sensitivity, and stability. However, MOX sensors have low selectivity to different gases, which leads to the problem of...

  • Feature Paper
  • Article
  • Open Access
12 Citations
6,525 Views
15 Pages

The Applications of Lattice Light-Sheet Microscopy for Functional Volumetric Imaging of Hippocampal Neurons in a Three-Dimensional Culture System

  • Chin-Yi Chen,
  • Yen-Ting Liu,
  • Chieh-Han Lu,
  • Po-Yi Lee,
  • Yun-Chi Tsai,
  • Jyun-Sian Wu,
  • Peilin Chen and
  • Bi-Chang Chen

11 September 2019

The characterization of individual cells in three-dimensions (3D) with very high spatiotemporal resolution is crucial for the development of organs-on-chips, in which 3D cell cultures are integrated with microfluidic systems. In this study, we report...

  • Feature Paper
  • Article
  • Open Access
27 Citations
6,555 Views
13 Pages

10 September 2019

Droplet microfluidics enables the generation of highly uniform emulsions with excellent stability, precise control over droplet volume, and morphology, which offer superior platforms over conventional technologies for material synthesis and biologica...

  • Review
  • Open Access
54 Citations
6,652 Views
19 Pages

10 September 2019

The capability of isolating and sorting specific types of cells is crucial in life science, particularly for the early diagnosis of lethal diseases and monitoring of medical treatments. Among all the micro-fluidics techniques for cell sorting, inerti...

  • Review
  • Open Access
7 Citations
5,472 Views
30 Pages

10 September 2019

This review introduces some important spin phenomena of organic molecules and solids and their devices: Organic spin injection and transport, organic spin valves, organic magnetic field effects, organic excited ferromagnetism, organic spin currents,...

  • Article
  • Open Access
25 Citations
7,011 Views
18 Pages

3D Printing of Metallic Microstructured Mould Using Selective Laser Melting for Injection Moulding of Plastic Microfluidic Devices

  • Nan Zhang,
  • Jinghang Liu,
  • Honggang Zhang,
  • Nigel J. Kent,
  • Dermot Diamond and
  • Michael D. Gilchrist

10 September 2019

A new method, a 3D printing technique, in particular, selective laser melting (SLM), has been used to fabricate moulds for the injection moulding of thermoplastic microfluidic chips that are suitable for prototyping and early stage scale-up. The micr...

  • Article
  • Open Access
1 Citations
3,744 Views
19 Pages

Trajectory Definition with High Relative Accuracy (HRA) by Parametric Representation of Curves in Nano-Positioning Systems

  • Lucía Díaz Pérez,
  • Beatriz Rubio Serrano,
  • José A. Albajez García,
  • José A. Yagüe Fabra,
  • Esmeralda Mainar Maza and
  • Marta Torralba Gracia

10 September 2019

Nanotechnology applications demand high accuracy positioning systems. Therefore, in order to achieve sub-micrometer accuracy, positioning uncertainty contributions must be minimized by implementing precision positioning control strategies. The positi...

  • Review
  • Open Access
134 Citations
12,965 Views
20 Pages

Blood Cells Separation and Sorting Techniques of Passive Microfluidic Devices: From Fabrication to Applications

  • Susana O. Catarino,
  • Raquel O. Rodrigues,
  • Diana Pinho,
  • João M. Miranda,
  • Graça Minas and
  • Rui Lima

10 September 2019

Since the first microfluidic device was developed more than three decades ago, microfluidics is seen as a technology that exhibits unique features to provide a significant change in the way that modern biology is performed. Blood and blood cells are...

  • Editorial
  • Open Access
1 Citations
1,998 Views
2 Pages

9 September 2019

The development of solid state gas sensors based on microtransducers and nanostructured

sensing materials is the key point in the design of new portable measurement systems with sensing and identification performances comparable with those of most s...

  • Article
  • Open Access
7 Citations
18,910 Views
19 Pages

8 September 2019

Dynamic random access memory (DRAM) circuits require periodic refresh operations to prevent data loss. As DRAM density increases, DRAM refresh overhead is even worse due to the increase of the refresh cycle time. However, because of few the cells in...

  • Article
  • Open Access
20 Citations
6,003 Views
9 Pages

A Resonant Z-Axis Aluminum Nitride Thin-Film Piezoelectric MEMS Accelerometer

  • Jian Yang,
  • Meng Zhang,
  • Yurong He,
  • Yan Su,
  • Guowei Han,
  • Chaowei Si,
  • Jin Ning,
  • Fuhua Yang and
  • Xiaodong Wang

6 September 2019

In this paper, we report a novel aluminum nitride (AlN) thin-film piezoelectric resonant accelerometer. Different from the ordinary MEMS (micro-electro-mechanical systems) resonant accelerometers, the entire structure of the accelerometer, including...

  • Article
  • Open Access
3 Citations
3,884 Views
7 Pages

A Nontoxic Battery with 3D-Printed Housing for On-Demand Operation of Microcontrollers in Microfluidic Sensors

  • Kai Sachsenheimer,
  • Christiane Richter,
  • Dorothea Helmer,
  • Frederik Kotz and
  • Bastian Ernst Rapp

4 September 2019

Microcontrollers have a low energy consumption and are convenient tools for the operation and readout of small lab-on-a-chip devices. The operation of microcontrollers for data collection and analysis is key for measurements and statistics in field e...

  • Article
  • Open Access
25 Citations
4,446 Views
17 Pages

Three-Dimensional Modeling of Avascular Tumor Growth in Both Static and Dynamic Culture Platforms

  • Ali Taghibakhshi,
  • Maryam Barisam,
  • Mohammad Said Saidi,
  • Navid Kashaninejad and
  • Nam-Trung Nguyen

31 August 2019

Microfluidic cell culture platforms are ideal candidates for modeling the native tumor microenvironment because they can precisely reconstruct in vivo cellular behavior. Moreover, mathematical modeling of tumor growth can pave the way toward descript...

  • Article
  • Open Access
17 Citations
3,957 Views
21 Pages

31 August 2019

Micro-milling is an emerging processing technology for machining micro- and high-precision three dimensional parts that require the use of various materials (with sizes ranging from tens of micrometers to a few millimeters) in the field of advanced m...

  • Article
  • Open Access
40 Citations
6,141 Views
19 Pages

Design, Modeling, and Testing of a Novel XY Piezo-Actuated Compliant Micro-Positioning Stage

  • Quan Zhang,
  • Jianguo Zhao,
  • Xin Shen,
  • Qing Xiao,
  • Jun Huang and
  • Yuan Wang

31 August 2019

A novel decoupled XY compliant micro-positioning stage, based on a bridge-type amplification mechanism and parallelogram mechanisms, is designed in this paper. Analytical models of the bridge-type amplification mechanism and parallelogram mechanisms...

  • Article
  • Open Access
40 Citations
7,011 Views
14 Pages

31 August 2019

This paper presents experimental investigations of passive mixing in a microfluidic channel with different zigzag angles. Zigzag channel is commonly used for microfluidic mixing because it does not need an additional control unit and can be easily im...

  • Article
  • Open Access
13 Citations
4,513 Views
17 Pages

31 August 2019

A novel combined actuation method based on the piezoelectric effect and liquid crystal backflow effect is proposed in this paper. The coupling mechanism of a piezoelectric transducer (PZT) and liquid crystal (LC) in a combined driving mode is analyze...

  • Article
  • Open Access
4 Citations
2,994 Views
15 Pages

31 August 2019

An experimentally validated mathematical model of a microfluidic device with nozzle-shaped electrode configuration for realizing dielectrophoresis based 3D-focusing is presented in the article. Two right-triangle shaped electrodes on the top and bott...

  • Communication
  • Open Access
11 Citations
3,679 Views
8 Pages

31 August 2019

A series of ultralong (up to tens of micrometers) MoO3 nanowire-based membranes were synthesized for the treatment of aqueous solutions containing the cationic dyes methylene blue (MB) and rhodamine B (RhB). This treatment method possesses extremely...

  • Article
  • Open Access
24 Citations
5,716 Views
12 Pages

31 August 2019

Recent advances in the microfabrication technology have made it possible to control surface properties at micro- and nanoscale levels. Functional surfaces drastically change wettability and condensation processes that are essential for controlling of...

  • Article
  • Open Access
10 Citations
2,997 Views
10 Pages

Tin Dioxide Thin Film with UV-enhanced Acetone Detection in Microwave Frequency Range

  • Artur Rydosz,
  • Kamil Staszek,
  • Andrzej Brudnik and
  • Slawomir Gruszczynski

30 August 2019

In this paper, the UV illumination effect for microwave gas sensors based on the tin dioxide was verified. A UV LED with emission wavelength close to the absorption edge of the SnO2 gas-sensing layer was selected as the UV source. The developed gas s...

  • Article
  • Open Access
33 Citations
4,670 Views
9 Pages

30 August 2019

This paper reports for the first time printed-circuit-board (PCB)-based label-free electrochemical detection of bacteria. The demonstrated immunosensor was implemented on a PCB sensing platform which was designed and fabricated in a standard PCB manu...

  • Article
  • Open Access
15 Citations
5,134 Views
16 Pages

Micro–Macro: Selective Integration of Microfeatures Inside Low-Cost Macromolds for PDMS Microfluidics Fabrication

  • Edgar Jiménez-Díaz,
  • Mariel Cano-Jorge,
  • Diego Zamarrón-Hernández,
  • Lucia Cabriales,
  • Francisco Páez-Larios,
  • Aarón Cruz-Ramírez,
  • Genaro Vázquez-Victorio,
  • Tatiana Fiordelisio and
  • Mathieu Hautefeuille

30 August 2019

Microfluidics has become a very promising technology in recent years, due to its great potential to revolutionize life-science solutions. Generic microfabrication processes have been progressively made available to academic laboratories thanks to cos...

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Micromachines - ISSN 2072-666X