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Nutrients, Volume 13, Issue 1

January 2021 - 280 articles

Cover Story: This narrative review provides an overview of the effect of coffee brew; its by-products; and its components on the gastrointestinal mucosa (mainly involved in permeability, secretion, and proliferation), the neural and non-neural components of the gut wall responsible for its motor function, and the brain–gut axis. Despite in vitro, in vivo, and epidemiological studies having shown that coffee may exert multiple effects on the digestive tract, including antioxidant, anti-inflammatory, and antiproliferative effects on the mucosa, and pro-motility effects on the external muscle layers, much is still surprisingly unknown. Further studies are needed to understand the mechanisms of action of certain health-promoting properties of coffee on the gastrointestinal tract and to transfer this knowledge to the industry to develop functional foods to improve the gastrointestinal and brain–gut axis health. View this paper
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Articles (280)

  • Article
  • Open Access
28 Citations
12,462 Views
12 Pages

19 January 2021

We explored the dose-response relations of sodium, potassium, magnesium and calcium with cardiovascular disease (CVD) risk in the Framingham Offspring Study, as well as the combined effects of these minerals. Analyses included 2362 30–64 year-o...

  • Review
  • Open Access
48 Citations
8,207 Views
17 Pages

Mechanisms of Dietary Sodium-Induced Impairments in Endothelial Function and Potential Countermeasures

  • Jordan C. Patik,
  • Shannon L. Lennon,
  • William B. Farquhar and
  • David G. Edwards

19 January 2021

Despite decades of efforts to reduce sodium intake, excess dietary sodium remains commonplace, and contributes to increased cardiovascular morbidity and mortality independent of its effects on blood pressure. An increasing amount of research suggests...

  • Article
  • Open Access
57 Citations
29,071 Views
14 Pages

Associations of Skipping Breakfast, Lunch, and Dinner with Weight Gain and Overweight/Obesity in University Students: A Retrospective Cohort Study

  • Ryohei Yamamoto,
  • Ryohei Tomi,
  • Maki Shinzawa,
  • Ryuichi Yoshimura,
  • Shingo Ozaki,
  • Kaori Nakanishi,
  • Seiko Ide,
  • Izumi Nagatomo,
  • Makoto Nishida and
  • Keiko Yamauchi-Takihara
  • + 2 authors

19 January 2021

Although multiple studies have identified skipping breakfast as a risk factor for weight gain, there is limited evidence on the clinical impact of skipping lunch and dinner on weight gain. This retrospective cohort study including 17,573 male and 886...

  • Review
  • Open Access
79 Citations
31,388 Views
20 Pages

19 January 2021

Globally, increasing rates of obesity are one of the most important health issues. The association between breakfast skipping and body weight is contradictory between cross-sectional and interventional studies. This systematic review and meta-analysi...

  • Review
  • Open Access
715 Citations
33,784 Views
30 Pages

Polyphenols and Human Health: The Role of Bioavailability

  • Chiara Di Lorenzo,
  • Francesca Colombo,
  • Simone Biella,
  • Creina Stockley and
  • Patrizia Restani

19 January 2021

Polyphenols are a group of phytochemicals with potential health-promoting effects. They are classified as flavonoid (flavonols, flavanols, flavones, flavanones, isoflavones, and anthocyanins) and non-flavonoid molecules (phenolic acids, hydroxycinnam...

  • Review
  • Open Access
52 Citations
13,742 Views
23 Pages

Effects of Caloric Restriction Diet on Arterial Hypertension and Endothelial Dysfunction

  • Nicola Di Daniele,
  • Giulia Marrone,
  • Manuela Di Lauro,
  • Francesca Di Daniele,
  • Daniela Palazzetti,
  • Cristina Guerriero and
  • Annalisa Noce

19 January 2021

The most common manifestation of cardiovascular (CV) diseases is the presence of arterial hypertension (AH), which impacts on endothelial dysfunction. CV risk is associated with high values of systolic and diastolic blood pressure and depends on the...

  • Review
  • Open Access
21 Citations
8,423 Views
36 Pages

The Potential Properties of Natural Compounds in Cardiac Stem Cell Activation: Their Role in Myocardial Regeneration

  • Cristina Carresi,
  • Miriam Scicchitano,
  • Federica Scarano,
  • Roberta Macrì,
  • Francesca Bosco,
  • Saverio Nucera,
  • Stefano Ruga,
  • Maria Caterina Zito,
  • Rocco Mollace and
  • Lorenza Guarnieri
  • + 6 authors

19 January 2021

Cardiovascular diseases (CVDs), which include congenital heart disease, rhythm disorders, subclinical atherosclerosis, coronary heart disease, and many other cardiac disorders, cause about 30% of deaths globally; representing one of the main health p...

  • Article
  • Open Access
22 Citations
8,442 Views
12 Pages

The Association between Serum Vitamin D Levels and Helicobacter pylori Presence and Eradication

  • Asher Shafrir,
  • Michal Shauly-Aharonov,
  • Lior H. Katz,
  • Ora Paltiel,
  • Yishai Pickman and
  • Zvi Ackerman

19 January 2021

Background: The success of Helicobacter pylori (H. pylori) eradication depends on several host and treatment factors. Serum vitamin D levels may be associated with H. pylori infection and eradication rates. We investigated the association between vit...

  • Review
  • Open Access
27 Citations
7,863 Views
24 Pages

19 January 2021

Vitamin D is an essential component of immune function and childhood deficiency is associated with an increased risk of acute lower respiratory infections (ALRIs). Globally, the leading childhood respiratory pathogens are Streptococcus pneumoniae, re...

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Nutrients - ISSN 2072-6643