Special Issue "Dietary Interventions in Chronic Kidney Disease"

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Public Health".

Deadline for manuscript submissions: 31 December 2020.

Special Issue Editor

Dr. Ion Alexandru Bobulescu
Guest Editor
Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79409, USA
Interests: molecular mechanisms of kidney injury and chronic kidney disease; role of iron in kidney disease; renal lipid metabolism and lipotoxicity; gut microbiota and the kidney; proximal tubule ion transport; renal handling and (patho)physiologic roles of uric acid

Special Issue Information

Dear Colleagues,

Chronic kidney disease (CKD) affects approximately one in every ten people worldwide, and is the cause of death for millions across the globe each year. In spite of major advances over the past decades, the mechanisms that contribute to the onset and progression of CKD remain incompletely understood, and our armamentarium of therapies for CKD patients remains relatively limited.

Because of its unique role in waste product excretion and whole-body fluid, mineral and acid-base homeostasis, the normal kidney is exquisitely sensitive and responsive to changes in dietary composition. The onset and progression of CKD add layers of complexity to the interplay between diet and the kidney, and there is mounting evidence that patients with CKD may benefit from dietary modifications aimed at improving symptoms, slowing progression, and preventing complications. However, there is still no consensus about optimal strategies for dietary intervention in CKD, taking into consideration each patient’s genetic, clinical, environmental, and sociodemographic characteristics.

In this Special Issue of Nutrients, we invite contributions dealing with various aspects of nutrition and dietary interventions in patients with CKD, including – but not limited to – papers on dietary phosphorus, sodium, potassium, acid-base, and protein intake. We welcome original research articles (clinical, translational or basic research), as well as meta-analyses and reviews.

Dr. Ion Alexandru Bobulescu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • chronic kidney disease
  • dietary phosphorus
  • dietary potassium
  • dietary sodium
  • dietary protein

Published Papers (1 paper)

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Open AccessArticle
Risk Reduction for End-Stage Renal Disease by Dietary Guidance Using the Gustatory Threshold Test for Salty Taste
Nutrients 2020, 12(9), 2703; https://doi.org/10.3390/nu12092703 - 04 Sep 2020
Educational hospitalization of patients with chronic kidney disease (CKD) may slow the progression of renal dysfunction. However, the educational aspect that is more effective has not been identified to date. In this study, patients with CKD were evaluated for gustatory threshold for salty [...] Read more.
Educational hospitalization of patients with chronic kidney disease (CKD) may slow the progression of renal dysfunction. However, the educational aspect that is more effective has not been identified to date. In this study, patients with CKD were evaluated for gustatory threshold for salty taste and received augmented salt reduction guidance under educational hospitalization at Nagasaki University Hospital from October 2016. In total, 277 eligible patients were enrolled and hospitalized from 2012 to 2019 (mean age of 69.2 years; men comprised 62.1%). We compared 141 patients (Group A) who were educated in the hospital after October 2016 and 136 patients (Group B) who received standard education in the hospital before October 2016. The changes in the estimated glomerular filtration rate (ΔeGFR) after hospitalization and dialysis induction rate within one year after hospitalization were evaluated. The ΔeGFR was significantly improved in Group A compared to Group B (A: 1.05 mL/min/1.73 m2/month, B: 0.55 mL/min/1.73 m2/month; p = 0.02). The dialysis induction rate was significantly lower in Group A than in Group B (A: 8.5%, B: 15.5%; p = 0.001). These trends were also observed by multivariate analyses. In conclusion, educational hospitalization with enhanced salt reduction guidance may reduce the risk of end-stage renal disease. Full article
(This article belongs to the Special Issue Dietary Interventions in Chronic Kidney Disease)
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