Nutrients, Volume 11, Issue 2 (February 2019) – 274 articles
Cover Story (view full-size image): Oral glucosamine sulfate (GS) and chondroitin sulfate (CS), while widely marketed as joint-protective supplements, have limited intestinal absorption and are predominantly utilized by gut microbiota. The effects of these supplements on the gut microbiome are of great interest, and may clarify their mode of action, or explain heterogeneity in therapeutic responses. We conducted a systematic review of animal and human studies reporting the effects of GS or CS on gut microbial composition. Included studies varied in design, supplementation protocols, and microbiome assessment methods, and described associations between CS supplementation and increased abundance of Bacteroides, Desulfovibrio piger, and Bacteroidales S24-7, as well as decreased abundance of Lactobacillus. We discuss the possible implications of these associations for the host. View this paper
- Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
- You may sign up for e-mail alerts to receive table of contents of newly released issues.
- PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.