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Nutrients, Volume 10, Issue 5 (May 2018)
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Cover Story (view full-size image) The authors investigated the impact of inulin on postprandial hypertriglyceridemia and on lipid [...] Read more. The authors investigated the impact of inulin on postprandial hypertriglyceridemia and on lipid metabolism in a mouse model of diet-induced obesity. The authors showed that inulin supplementation strongly decreases postprandial serum triglycerides concentration, by lessening mRNA expression of Cd36 (a fatty acid receptor involved in lipid uptake and sensing) and apolipoprotein C3 (Apoc3, an inhibitor of lipoprotein lipase) in the jejunum, and by increasing fecal lipid excretion. This work brings new mechanisms by which inulin supplementation may help managing the dyslipidemia linked to obesity and cardiometabolic risk. View this paper