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Nutrients, Volume 10, Issue 4

April 2018 - 142 articles

Cover Story: Here meta-analysis and experimental data demonstrate a link between protein biosynthesis impairment and neurodegeneration such as Alzheimer’s disease (AD). Protein biosynthesis reduces at step of tRNA aminoacylation in AD patients. Inhibitors of tryptophanyl-tRNA synthetase (TrpRS), an enzyme of protein biosynthesis cause such decrease. Gut microbiome produce TrpRS inhibitors - tryptamine, tryptophanol and indoleacetic acid. Tryptamine and tryptophanol induce neurotoxicity and formation of fibrillary tangles similar to those detected in AD brain. Monoamine oxidases (MAO) degrade tryptamine into indoleacetic acid. Tryptamine presents in food. Dietary supplements and antibiotics can increase tryptamine content in stool. Tryptamine easily crosses blood-brain barrier and induces pathology in brain blood vessels. Combination of high tryptamine with MAO inhibitors prescribed as anti-depressants can be lethal. View this paper
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Articles (142)

  • Article
  • Open Access
15 Citations
7,413 Views
16 Pages

Design and Reproducibility of a Mini-Survey to Evaluate the Quality of Food Intake (Mini-ECCA) in a Mexican Population

  • María Fernanda Bernal-Orozco,
  • Nayeli Badillo-Camacho,
  • Gabriela Macedo-Ojeda,
  • Montserrat González-Gómez,
  • Jaime Fernando Orozco-Gutiérrez,
  • Ruth Jackelyne Prado-Arriaga,
  • Fabiola Márquez-Sandoval,
  • Martha Betzaida Altamirano-Martínez and
  • Barbara Vizmanos

23 April 2018

Evaluating food intake quality may contribute to the development of nutrition programs. In Mexico, there are no screening tools that can be administered quickly for the evaluation of this variable. The aim was to determine the reproducibility of a mi...

  • Article
  • Open Access
21 Citations
8,458 Views
10 Pages

23 April 2018

Chlorogenic acids (CGAs) reduce blood pressure and body fat, and enhance fat metabolism. In roasted coffee, CGAs exist together with the oxidant component hydroxyhydroquinone (HHQ). HHQ counteracts the antihypertensive effects of CGA, but its effects...

  • Brief Report
  • Open Access
48 Citations
7,605 Views
8 Pages

Neurotensin Is a Lipid-Induced Gastrointestinal Peptide Associated with Visceral Adipose Tissue Inflammation in Obesity

  • Ilaria Barchetta,
  • Flavia Agata Cimini,
  • Danila Capoccia,
  • Laura Bertoccini,
  • Valentina Ceccarelli,
  • Caterina Chiappetta,
  • Frida Leonetti,
  • Claudio Di Cristofano,
  • Gianfranco Silecchia and
  • Marju Orho-Melander
  • + 2 authors

23 April 2018

Neurotensin (NT) is a 13-amino acid peptide localized in the neuroendocrine cells of the small intestine, which promotes fat absorption and fatty acids translocation in response to lipid ingestion. NT-knock-out mice fed with a high-fat diet are prote...

  • Article
  • Open Access
22 Citations
10,510 Views
15 Pages

Infant Feeding Attitudes and Practices of Spanish Low-Risk Expectant Women Using the IIFAS (Iowa Infant Feeding Attitude Scale)

  • María Del Carmen Suárez Cotelo,
  • María Jesús Movilla-Fernández,
  • Paula Pita-García and
  • Silvia Novío

22 April 2018

The Iowa Infant Feeding Attitude Scale (IIFAS) has been shown to have good psychometric properties for English-speaking populations, but it has not been validated among low-risk pregnant women in Spain. The aim of this study was to assess the reliabi...

  • Article
  • Open Access
20 Citations
6,023 Views
15 Pages

22 April 2018

The application of starter cultures to improve quality and safety has become a very common practice in the meat industry. Probiotic strains of lactic acid bacteria (LAB) can also bring health benefits by releasing bioactive peptides. The aim of this...

  • Review
  • Open Access
392 Citations
51,492 Views
12 Pages

Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review

  • Sergio Davinelli,
  • Michael E. Nielsen and
  • Giovanni Scapagnini

22 April 2018

Astaxanthin, a xanthophyll carotenoid, is a secondary metabolite naturally synthesized by a number of bacteria, microalgae, and yeasts. The commercial production of this pigment has traditionally been performed by chemical synthesis, but the microalg...

  • Article
  • Open Access
14 Citations
6,223 Views
11 Pages

Ethanol Extract of Evodia rutaecarpa Attenuates Cell Growth through Caspase-Dependent Apoptosis in Benign Prostatic Hyperplasia-1 Cells

  • Eunsook Park,
  • Mee-Young Lee,
  • Chang-Seob Seo,
  • Ji-Hye Jang,
  • Yong-ung Kim and
  • Hyeun-Kyoo Shin

22 April 2018

The dried fruits of Evodia rutaecarpa Bentham have been used widely as a herbal medicine for the treatment of inflammatory disorders and abdominal pain. Benign prostatic hyperplasia (BPH) is a nonmalignant disease characterized by overgrowth of prost...

  • Article
  • Open Access
2 Citations
6,172 Views
19 Pages

Regression Analysis to Identify Factors Associated with Urinary Iodine Concentration at the Sub-National Level in India, Ghana, and Senegal

  • Jacky Knowles,
  • Roland Kupka,
  • Sam Dumble,
  • Greg S. Garrett,
  • Chandrakant S. Pandav,
  • Kapil Yadav,
  • Ndeye Khady Touré,
  • Esi Foriwa Amoaful and
  • Jonathan Gorstein

21 April 2018

Single and multiple variable regression analyses were conducted using data from stratified, cluster sample design, iodine surveys in India, Ghana, and Senegal to identify factors associated with urinary iodine concentration (UIC) among women of repro...

  • Review
  • Open Access
84 Citations
20,650 Views
9 Pages

Acid Balance, Dietary Acid Load, and Bone Effects—A Controversial Subject

  • Lynda Frassetto,
  • Tanushree Banerjee,
  • Neil Powe and
  • Anthony Sebastian

21 April 2018

Modern Western diets, with higher contents of animal compared to fruits and vegetable products, have a greater content of acid precursors vs. base precursors, which results in a net acid load to the body. To prevent inexorable accumulation of acid in...

  • Article
  • Open Access
16 Citations
7,507 Views
15 Pages

21 April 2018

The aim of this work was to assess the accuracy of automatic macronutrient and calorie counting based on voice descriptions of meals provided by people with unstable type 1 diabetes using the developed expert system (VoiceDiab) in comparison with ref...

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Nutrients - ISSN 2072-6643