You are currently viewing a new version of our website. To view the old version click .

29 Results Found

  • Review
  • Open Access
296 Citations
14,274 Views
18 Pages

Antitumor Activities of Metal Oxide Nanoparticles

  • Maria Pilar Vinardell and
  • Montserrat Mitjans

9 June 2015

Nanoparticles have received much attention recently due to their use in cancer therapy. Studies have shown that different metal oxide nanoparticles induce cytotoxicity in cancer cells, but not in normal cells. In some cases, such anticancer activity...

  • Review
  • Open Access
39 Citations
5,146 Views
34 Pages

7 April 2022

Titanium dioxide (TiO2) and zinc oxide (ZnO) nanoparticles (NPs) have attracted a great deal of attention due to their excellent electrical, optical, whitening, UV-adsorbing and bactericidal properties. The extensive production and utilization of the...

  • Review
  • Open Access
49 Citations
4,424 Views
17 Pages

High Potency of Organic and Inorganic Nanoparticles to Treat Cystic Echinococcosis: An Evidence-Based Review

  • Aishah E. Albalawi,
  • Abdullah D. Alanazi,
  • Parastoo Baharvand,
  • Maryam Sepahvand and
  • Hossein Mahmoudvand

17 December 2020

Since there is no potential, effective vaccine available, treatment is the only controlling option against hydatid cyst or cystic echinococcosis (CE). This study was designed to systematically review the in vitro, in vivo, and ex vivo effects of nano...

  • Review
  • Open Access
23 Citations
4,724 Views
16 Pages

Engineered Metal Oxide Nanoparticles as Fungicides for Plant Disease Control

  • Aida R. Cruz-Luna,
  • Alfonso Vásquez-López,
  • Hugo Rojas-Chávez,
  • Manuel A. Valdés-Madrigal,
  • Heriberto Cruz-Martínez and
  • Dora I. Medina

27 June 2023

Metal oxide nanoparticles are considered to be good alternatives as fungicides for plant disease control. To date, numerous metal oxide nanoparticles have been produced and evaluated as promising antifungal agents. Consequently, a detailed and critic...

  • Review
  • Open Access
202 Citations
28,367 Views
42 Pages

Nanotoxicology of Metal Oxide Nanoparticles

  • Amedea B. Seabra and
  • Nelson Durán

3 June 2015

This review discusses recent advances in the synthesis, characterization and toxicity of metal oxide nanoparticles obtained mainly through biogenic (green) processes. The in vitro and in vivo toxicities of these oxides are discussed including a consi...

  • Review
  • Open Access
52 Citations
4,052 Views
18 Pages

Analysis of the Exposure of Organisms to the Action of Nanomaterials

  • Anita Staroń,
  • Olga Długosz,
  • Jolanta Pulit-Prociak and
  • Marcin Banach

12 January 2020

The rapid development of the production of materials containing metal nanoparticles and metal oxides is a potential risk to the environment. The degree of exposure of organisms to nanoparticles increases from year to year, and its effects are not ful...

  • Review
  • Open Access
25 Citations
5,878 Views
34 Pages

Current Trends and Prospects for Application of Green Synthesized Metal Nanoparticles in Cancer and COVID-19 Therapies

  • Londiwe Simphiwe Mbatha,
  • Jude Akinyelu,
  • Chika Ifeanyi Chukwuma,
  • Mduduzi Paul Mokoena and
  • Tukayi Kudanga

13 March 2023

Cancer and COVID-19 have been deemed as world health concerns due to the millions of lives that they have claimed over the years. Extensive efforts have been made to develop sophisticated, site-specific, and safe strategies that can effectively diagn...

  • Review
  • Open Access
289 Citations
15,019 Views
21 Pages

17 October 2017

The development of different kinds of nanoparticles, showing different physico-chemical properties, has fostered their large use in many fields, including medicine. As a consequence, inorganic nanoparticles (e.g., metals or semiconductors), have rais...

  • Review
  • Open Access
1 Citations
3,037 Views
20 Pages

Application of Metal Oxide Nanoparticles in Different Carcinomas

  • Nutan Rani,
  • Yousuf Khan,
  • Sapna Yadav,
  • Kalawati Saini and
  • Dipak Maity

20 December 2024

Metal oxide nanoparticles (MONPs) have recently attracted much attention from researchers due to their use in cancer chemotherapy, targeted drug delivery, and diagnosis/MRI imaging. Various studies have demonstrated that different metal oxide NPs sho...

  • Review
  • Open Access
22 Citations
3,059 Views
27 Pages

Wound infection due to bacterial invasion at the wound site is one of the primary challenges associated with delayed wound healing. Microorganisms tend to form biofilms that protect them from harm, leading to their multidrug resistance. The alarming...

  • Review
  • Open Access
103 Citations
11,416 Views
26 Pages

Zinc oxide (ZnO) nanoparticles have been studied as metal-based drugs that may be used for biomedical applications due to the fact of their biocompatibility. Their physicochemical properties, which depend on synthesis techniques involving physical, c...

  • Review
  • Open Access
29 Citations
5,950 Views
15 Pages

20 January 2022

Although radiation therapy (RT) is one of the mainstays of head and neck cancer (HNC) treatment, innovative approaches are needed to further improve treatment outcomes. A significant challenge has been to design delivery strategies that focus high do...

  • Review
  • Open Access
14 Citations
3,997 Views
35 Pages

Potential Applications of Rare Earth Metal Nanoparticles in Biomedicine

  • Svetlana A. Titova,
  • Maria P. Kruglova,
  • Victor A. Stupin,
  • Natalia E. Manturova and
  • Ekaterina V. Silina

24 January 2025

In recent years, the world scientific community has shown increasing interest in rare earth metals in general and their nanoparticles in particular. Medicine and pharmaceuticals are no exception in this matter. In this review, we have considered the...

  • Review
  • Open Access
78 Citations
6,422 Views
20 Pages

Metal-Based Nanoparticles and Their Relevant Consequences on Cytotoxicity Cascade and Induced Oxidative Stress

  • Yunhui Min,
  • Godagama Gamaarachchige Dinesh Suminda,
  • Yunji Heo,
  • Mangeun Kim,
  • Mrinmoy Ghosh and
  • Young-Ok Son

Emerging nanoscience allows us to take advantage of the improved evolutionary components and apply today’s advanced characterization and fabrication techniques to solve environmental and biological problems. Despite the promise that nanotechnol...

  • Article
  • Open Access
37 Citations
5,269 Views
21 Pages

Iron Oxide Incorporated Conjugated Polymer Nanoparticles for Simultaneous Use in Magnetic Resonance and Fluorescent Imaging of Brain Tumors

  • Nuria Arias-Ramos,
  • Luis Exequiel Ibarra,
  • María Serrano-Torres,
  • Balbino Yagüe,
  • Matías Daniel Caverzán,
  • Carlos Alberto Chesta,
  • Rodrigo Emiliano Palacios and
  • Pilar López-Larrubia

Conjugated polymer nanoparticles (CPNs) have emerged as advanced polymeric nanoplatforms in biomedical applications by virtue of extraordinary properties including high fluorescence brightness, large absorption coefficients of one and two-photons, an...

  • Review
  • Open Access
36 Citations
4,916 Views
48 Pages

The ambition to combat the issues affecting the environment and human health triggers the development of biosynthesis that incorporates the production of natural compounds by living organisms via eco-friendly nano assembly. Biosynthesized nanoparticl...

  • Review
  • Open Access
53 Citations
5,438 Views
31 Pages

Metal Oxide Nanoparticles: Evidence of Adverse Effects on the Male Reproductive System

  • Mariana Vassal,
  • Sandra Rebelo and
  • Maria de Lourdes Pereira

Metal oxide nanoparticles (MONPs) are inorganic materials that have become a valuable tool for many industrial sectors, especially in healthcare, due to their versatility, unique intrinsic properties, and relatively inexpensive production cost. As a...

  • Article
  • Open Access
9 Citations
2,664 Views
17 Pages

Titanium Dioxide Nano-Formulation: Characterization, Antimicrobial Activity, and Wound Healing in Animals

  • Noppason Pangprasit,
  • Yada Thammawong,
  • Alongkorn Kulsirorat,
  • Phongsakorn Chuammitri,
  • Aphisek Kongkaew,
  • Montira Intanon,
  • Witaya Suriyasathaporn,
  • Surachai Pikulkaew and
  • Wasana Chaisri

22 August 2023

The use of metal oxide nanoparticles as an alternative antimicrobial agent has gained attention due to the increasing problem of antimicrobial resistance. Understanding its properties and potential benefits can contribute to the development of more e...

  • Article
  • Open Access
7 Citations
3,162 Views
14 Pages

Toxicity Assessment of New Ag-ZnO/AgO Nanocomposites: An In Vitro and In Vivo Approach

  • José Rodrigues do Carmo Neto,
  • Pablo Igor Ribeiro Franco,
  • Yarlla Loyane Lira Braga,
  • Jordana Fernandes de Oliveira,
  • Hugo Felix Perini,
  • Luís Fernando Duarte Albuquerque,
  • Danieli Brolo Martins,
  • Fernanda Rodrigues Helmo,
  • Anderson Assunção Andrade and
  • Marina Pacheco Miguel
  • + 5 authors

Zinc oxide nanoparticles (ZnO NPs) are metal oxide nanomaterials, which are important for several applications: antibacterial, anthelmintic, antiprotozoal and antitumoral, among others. These applications are mainly related to the ability to spontane...

  • Article
  • Open Access
125 Citations
8,856 Views
21 Pages

Synthesis of Magnetic Ferrite Nanoparticles with High Hyperthermia Performance via a Controlled Co-Precipitation Method

  • Mohamed S. A. Darwish,
  • Hohyeon Kim,
  • Hwangjae Lee,
  • Chiseon Ryu,
  • Jae Young Lee and
  • Jungwon Yoon

16 August 2019

Magnetic nanoparticles (MNPs) that exhibit high specific loss power (SLP) at lower metal content are highly desirable for hyperthermia applications. The conventional co-precipitation process has been widely employed for the synthesis of magnetic nano...

  • Review
  • Open Access
2,253 Views
18 Pages

Cardiovascular Toxicity of Metal-Based Nanoparticles

  • Eun-Hye Kim,
  • Sehyeon Park and
  • Ok-Nam Bae

The rapid development of nanotechnology has led to increased human exposure to metal-based nanoparticles (MNPs) through inhalation, ingestion, and dermal contact, raising growing concerns on their potential health effects. Due to their nanoscale size...

  • Review
  • Open Access
6 Citations
4,359 Views
24 Pages

11 February 2023

Ferroptosis was first reported as a separate modality of regulated cell death in 2008 and distinguished under its current name in 2012 after it was first induced with erastin. In the following decade, multiple other chemical agents were researched fo...

  • Article
  • Open Access
27 Citations
3,693 Views
13 Pages

Low Toxicity of Metal-Organic Framework MOF-74(Co) Nano-Particles In Vitro and In Vivo

  • Suke Lan,
  • Jiahao Zhang,
  • Xin Li,
  • Lejie Pan,
  • Juncheng Li,
  • Xian Wu and
  • Sheng-Tao Yang

28 September 2022

With the rapid development of metal-organic frameworks (MOF), the toxicity and environmental safety of MOF materials should be thoroughly investigated. The behaviors and bio-effects of MOF materials after oral exposure are largely unknown. In this st...

  • Brief Report
  • Open Access
16 Citations
4,069 Views
11 Pages

22 November 2019

Currently, there is a great interest in nanoparticle-based vaccine delivery. Recent studies suggest that nanoparticles when introduced into the biological milieu are not simply passive carriers but may also contribute immunological activity themselve...

  • Review
  • Open Access
1 Citations
2,258 Views
45 Pages

Magnetic Hyperthermia with Iron Oxide Nanoparticles: From Toxicity Challenges to Cancer Applications

  • Ioana Baldea,
  • Cristian Iacoviță,
  • Raul Andrei Gurgu,
  • Alin Stefan Vizitiu,
  • Vlad Râzniceanu and
  • Daniela Rodica Mitrea

4 October 2025

Iron oxide nanoparticles (IONPs) have emerged as key materials in magnetic hyperthermia (MH), a minimally invasive cancer therapy capable of selectively inducing apoptosis, ferroptosis, and other cell death pathways while sparing surrounding healthy...

  • Review
  • Open Access
112 Citations
11,368 Views
49 Pages

31 August 2020

This article presents a state-of-the-art review and analysis of literature studies on the morphological structure, fabrication, cytotoxicity, and photocatalytic toxicity of zinc oxide nanostructures (nZnO) of mammalian cells. nZnO with different morp...

  • Article
  • Open Access
2 Citations
2,781 Views
18 Pages

A Novel Experimental Approach to Understand the Transport of Nanodrugs

  • Soubantika Palchoudhury,
  • Parnab Das,
  • Amirehsan Ghasemi,
  • Syed Mohammed Tareq,
  • Sohini Sengupta,
  • Jinchen Han,
  • Sarah Maglosky,
  • Fajer Almanea,
  • Madison Jones and
  • Collin Cox
  • + 1 author

5 August 2023

Nanoparticle-based drugs offer attractive advantages like targeted delivery to the diseased site and size and shape-controlled properties. Therefore, understanding the particulate flow of the nanodrugs is important for effective delivery, accurate pr...

  • Article
  • Open Access
31 Citations
3,513 Views
25 Pages

Background: Multidrug resistant MDR bacterial strains are causing fatal infections, such as mastitis. Thus, there is a need for the development of new target-oriented antimicrobials. Nanomaterials have many advantages over traditional antibiotics, in...

  • Review
  • Open Access
1,999 Citations
64,357 Views
24 Pages

The Effects of Cadmium Toxicity

  • Giuseppe Genchi,
  • Maria Stefania Sinicropi,
  • Graziantonio Lauria,
  • Alessia Carocci and
  • Alessia Catalano

Cadmium (Cd) is a toxic non-essential transition metal that poses a health risk for both humans and animals. It is naturally occurring in the environment as a pollutant that is derived from agricultural and industrial sources. Exposure to cadmium pri...