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28 Results Found

  • Article
  • Open Access
2 Citations
10,520 Views
13 Pages

9 November 2010

Hypotension is frequently reported during hemodialysis. This study aimed to examine the effect of the intermittent pneumatic circulator on blood pressure during hemodialysis. Sixteen subjects with chronic hemodialysis were recruited. Each subject ran...

  • Article
  • Open Access
2 Citations
6,024 Views
14 Pages

Hemodialysis without Systemic Anticoagulation: A Randomized Controlled Trial to Evaluate Five Strategies in Patients at a High Risk of Bleeding

  • Pedro H. Franca Gois,
  • David McIntyre,
  • Sharad Ratanjee,
  • Anita Pelecanos,
  • Carla Scuderi,
  • Chungun L. Janoschka,
  • Kara Summers,
  • Haibing Wu,
  • Belinda Elford and
  • Helen G. Healy
  • + 1 author

4 August 2024

Background: There has been growing interest in exploring combined interventions to achieve a more effective heparin-free treatment approach. Aim: to evaluate combination of interventions compared to standard practice (intermittent flushes) to prevent...

  • Article
  • Open Access
9 Citations
2,897 Views
13 Pages

Impact of Renal Replacement Therapy on Mortality and Renal Outcomes in Critically Ill Patients with Acute Kidney Injury: A Population-Based Cohort Study in Korea between 2008 and 2015

  • Subin Hwang,
  • Danbee Kang,
  • Hyejeong Park,
  • Youngha Kim,
  • Eliseo Guallar,
  • Junseok Jeon,
  • Jung-Eun Lee,
  • Wooseong Huh,
  • Gee-Young Suh and
  • Hye-Ryoun Jang
  • + 1 author

24 April 2022

The outcomes depending on the type of renal replacement therapy (RRT) or pre-existing kidney disease in critically ill patients with acute kidney injury (AKI) have not been fully elucidated. All adult intensive care unit patients with AKI in Korea fr...

  • Article
  • Open Access
4,051 Views
12 Pages

Therapeutic Drug Monitoring of Vancomycin in Hemodialysis Patients in a Hospital in North-East Romania

  • Aurelia Crețu,
  • Luanda Irina Mititiuc,
  • Iulia-Daniela Lungu,
  • Mihaela Mihaila,
  • Irina Dima,
  • Adrian Covic and
  • Cristina Mihaela Ghiciuc

Background/Objectives: Vancomycin is a reserve antibiotic that is frequently prescribed for central venous catheter (CVC)-associated infections in hemodialysis patients. Hemodialysis patients are very fragile patients and the presence of CVCs increas...

  • Article
  • Open Access
1 Citations
3,108 Views
18 Pages

Autonomic Nerve Activation Observed for Hemodialysis Patients While Squeezing a Soft Ball

  • Jian-Chiun Liou,
  • Chih-Wei Peng,
  • Philippe Basset and
  • Zhen-Xi Chen

19 November 2020

In this study, a medical grade pulse rate (PR) instrument was used to monitor hemodialysis patients, and the wearable product was applied for the 4 h observation. Electrocardiogram (ECG) and photoplethysmography (PPG) data were simultaneously collect...

  • Case Report
  • Open Access
1 Citations
20,789 Views
7 Pages

9 October 2024

A 5-year-old castrated male American Shorthair cat presented with lethargy and anorexia after accidentally knocking over a bottle of topical minoxidil and spilling it onto its body. Physical examination revealed rapid shallow breathing, pale mucous m...

  • Article
  • Open Access
1,690 Views
14 Pages

Prospective Audit and Feedback for Antimicrobial Treatment of Patients Receiving Renal Replacement Therapy in Community-Based University Hospitals: A before-and-after Study

  • Namgi Park,
  • Jiyeon Bae,
  • Soo Yeon Nam,
  • Ji Yun Bae,
  • Kang-Il Jun,
  • Jeong-Han Kim,
  • Chung-Jong Kim,
  • Kyunghee Kim,
  • Sun Ah Kim and
  • Sandy Jeong Rhie
  • + 1 author

In South Korea, because of manpower and budgetary limitations, antimicrobial stewardship programs have relied on preauthorization. This study analyzed the impact of a prospective audit and feedback (PAF) program targeting inpatients undergoing interm...

  • Article
  • Open Access
18 Citations
4,911 Views
11 Pages

Safe Practice of Y-Site Drug Administration: The Case of Colistin and Parenteral Nutrition

  • Maciej Stawny,
  • Aleksandra Gostyńska,
  • Malwina Nadolna and
  • Anna Jelińska

A serious problem in everyday clinical practice is the co-administration of drugs using the same infusion line. Potential complications of co-administration of incompatible drugs include precipitation in the infusion line or central venous catheter l...

  • Article
  • Open Access
1 Citations
2,620 Views
10 Pages

Calcium-Free Dialysate Hemodialysis: A Simplified Approach

  • Alexandra Corbu,
  • Florian Terrec,
  • Paolo Malvezzi,
  • Arnaud Jouzier,
  • Thomas Jouve,
  • Lionel Rostaing and
  • Hamza Naciri Bennani

20 June 2024

Intermittent hemodialysis (HD) in high-bleeding-risk patients presents a challenge as circuit anticoagulation using heparin is contraindicated in such cases. Recently, the use of calcium-free citrate-containing dialysate with calcium supplementation...

  • Review
  • Open Access
2,169 Views
17 Pages

3 September 2025

The number of patients with end-stage renal disease continues to grow worldwide, placing increasing demands on dialysis technologies. Conventional hemodialysis remains the dominant modality but is often limited by frequent intradialytic hypotension a...

  • Opinion
  • Open Access
22 Citations
7,995 Views
9 Pages

7 February 2020

Acute kidney injury is very common in critically ill patients requiring renal replacement therapy. Despite the advancement in medicine, the mortality rate from septic shock can be as high as 60%. This manuscript describes drug-dosing considerations a...

  • Article
  • Open Access
4 Citations
4,693 Views
13 Pages

Renal Embolization-Induced Uremic Swine Model for Assessment of Next-Generation Implantable Hemodialyzers

  • Jarrett Moyer,
  • Mark W. Wilson,
  • Thomas A. Sorrentino,
  • Ana Santandreu,
  • Caressa Chen,
  • Dean Hu,
  • Amy Kerdok,
  • Edward Porock,
  • Nathan Wright and
  • Shuvo Roy
  • + 5 authors

4 September 2023

Reliable models of renal failure in large animals are critical to the successful translation of the next generation of renal replacement therapies (RRT) into humans. While models exist for the induction of renal failure, none are optimized for the im...

  • Article
  • Open Access
9 Citations
10,494 Views
10 Pages

9 December 2021

Background: Critically ill patients with coronavirus disease 2019 (COVID-19) and kidney dysfunction often require tunneled hemodialysis catheter (TDC) placement for kidney replacement therapy, typically under fluoroscopic guidance to minimize cathete...

  • Article
  • Open Access
5 Citations
2,714 Views
13 Pages

Intradialytic Tolerance and Recovery Time in Different High-Efficiency Hemodialysis Modalities

  • Agnieszka Zakrzewska,
  • Jan Biedunkiewicz,
  • Michał Komorniczak,
  • Magdalena Jankowska,
  • Katarzyna Jasiulewicz,
  • Natalia Płonka,
  • Bogdan Biedunkiewicz,
  • Sylwia Małgorzewicz,
  • Agnieszka Tarasewicz and
  • Leszek Tylicki
  • + 3 authors

6 January 2024

There are several forms of maintenance high-efficiency hemodialysis (HD), including hemodiafiltrations (HDF) in different technical modes and expanded HD, using dialyzers with medium cut-off membranes. The aim of the study was to assess the intradial...

  • Review
  • Open Access
2 Citations
3,790 Views
6 Pages

24 February 2022

Acute kidney injury (AKI) is frequent, and shows wide variation with regards to the spectrum, etio-pathogenesis and management strategies after natural (e.g., earthquakes) and man-made disasters (e.g., wars). The most important pathogenetic mechanism...

  • Article
  • Open Access
2,520 Views
15 Pages

The Impact of Potassium Dynamics on Cardiomyocyte Beating in Hemodialysis Treatment

  • Hiroyuki Hamada,
  • Tadashi Tomo,
  • Sung-Teh Kim and
  • Akihiro C. Yamashita

15 April 2024

Background: Observational studies of intermittent hemodialysis therapy have reported that the excess decrease in K+ concentration in plasma (KP) during treatment is associated with the destabilization of cardiac function. Elucidating the mechanism by...

  • Article
  • Open Access
22 Citations
7,638 Views
17 Pages

Evaluation of Hemodialysis Arteriovenous Bruit by Deep Learning

  • Keisuke Ota,
  • Yousuke Nishiura,
  • Saki Ishihara,
  • Hihoko Adachi,
  • Takehisa Yamamoto and
  • Takayuki Hamano

27 August 2020

Physical findings of auscultation cannot be quantified at the arteriovenous fistula examination site during daily dialysis treatment. Consequently, minute changes over time cannot be recorded based only on subjective observations. In this study, we s...

  • Viewpoint
  • Open Access
5 Citations
4,072 Views
11 Pages

The Efficacy of Renal Replacement Therapy for Rewarming of Patients in Severe Accidental Hypothermia—Systematic Review of the Literature

  • Konrad Mendrala,
  • Sylweriusz Kosiński,
  • Paweł Podsiadło,
  • Mathieu Pasquier,
  • Peter Paal,
  • Piotr Mazur and
  • Tomasz Darocha

Background: Renal replacement therapy (RRT) can be used to rewarm patients in deep hypothermia. However, there is still no clear evidence for the effectiveness of RRT in this group of patients. This systematic review aims to summarize the rewarming r...

  • Review
  • Open Access
94 Citations
21,412 Views
14 Pages

12 February 2022

Vancomycin is the most frequently used antibiotic, accounting for up to 35% of hospitalized patients with infection, because of its optimal bactericidal effectiveness and relatively low price. Vancomycin-associated AKI (VA-AKI) is a clinically releva...

  • Article
  • Open Access
8 Citations
3,101 Views
13 Pages

Validation and Clinical Application of a New Liquid Chromatography Coupled to Mass Spectrometry (HPLC-MS) Method for Dalbavancin Quantification in Human Plasma

  • Valeria Avataneo,
  • Miriam Antonucci,
  • Elisa Delia De Vivo,
  • Antonio Briozzo,
  • Jessica Cusato,
  • Francesca Bermond,
  • Corrado Vitale,
  • Francesco Vitale,
  • Alessandra Manca and
  • Antonio D’Avolio
  • + 4 authors

Dalbavancin (DBV) is an intravenous long-acting second-generation glycolipopeptide antibiotic with high efficacy and excellent tolerability, approved for use in the treatment of Gram-positive skin and skin structure infections (ABSSSI). Nevertheless,...

  • Case Report
  • Open Access
1,679 Views
8 Pages

An Unusual Case of Anuric Acute Kidney Injury Secondary to the Use of Low-Dose Acetazolamide as Preventive Management for Acute Mountain Sickness

  • Marco Dominguez Davalos,
  • Raúl Valenzuela Córdova,
  • Celia Rodríguez Tudero,
  • Elena Jiménez Mayor,
  • Carlos Bedia Castillo,
  • José C. De La Flor,
  • Roger Leon Montesinos,
  • Cristian León Rabanal,
  • Michael Cieza Terrones and
  • Javier A. Neyra

21 July 2025

Background/Objectives: Acetazolamide is widely used for acute mountain sickness (AMS) prophylaxis. Whilst generally safe, acute kidney injury (AKI) is a rare but serious adverse event. We present a case of anuric AKI following minimal exposure to ace...

  • Article
  • Open Access
5 Citations
3,462 Views
16 Pages

Pre-Analytical and Clinical Validation of a Dried Blood Spot Assay for Asymmetric Dimethylarginine and L-Arginine

  • Juliane Hannemann,
  • Thore I. Roskam,
  • Ina Eilermann,
  • Patricia Siques,
  • Julio Brito and
  • Rainer Böger

9 April 2020

Asymmetric dimethylarginine (ADMA) inhibits nitric oxide (NO) synthesis. It is a risk marker for cardiovascular events and mortality in patients with cardiometabolic diseases and in population-based studies. Plasma or serum analysis of ADMA may be ha...

  • Article
  • Open Access
12 Citations
6,554 Views
9 Pages

Impact of Moderna mRNA-1273 Booster Vaccine on Fully Vaccinated High-Risk Chronic Dialysis Patients after Loss of Humoral Response

  • Sammy Patyna,
  • Timon Eckes,
  • Benjamin F. Koch,
  • Stephan Sudowe,
  • Anke Oftring,
  • Niko Kohmer,
  • Holger F. Rabenau,
  • Sandra Ciesek,
  • Despina Avaniadi and
  • Christoph Betz
  • + 3 authors

11 April 2022

The long-term effect of protection by two doses of SARS-CoV-2 vaccination in patients receiving chronic intermittent hemodialysis (CIHD) is an urging question. We investigated the humoral and cellular immune response of 42 CIHD patients who had recei...

  • Review
  • Open Access
10 Citations
12,248 Views
11 Pages

Weaning from Kidney Replacement Therapy in the Critically Ill Patient with Acute Kidney Injury

  • Kada Klouche,
  • Vincent Brunot,
  • Romaric Larcher and
  • Alexandre Lautrette

19 January 2024

Around 10% of critically ill patients suffer acute kidney injury (AKI) requiring kidney replacement therapy (KRT), with a mortality rate approaching 50%. Although most survivors achieve sufficient renal recovery to be weaned from KRT, there are no re...

  • Case Report
  • Open Access
2 Citations
3,174 Views
9 Pages

Supportive Treatment of a Dog with Leishmaniosis and Severe Glomerulopathy with Immunoadsorption

  • Florian Sänger,
  • Michèle Bergmann,
  • Katrin Hartmann and
  • René Dörfelt

21 February 2024

A three-year-old, intact female mix-breed dog, weighing 30 kg, was presented due to vomitus and diarrhea. At presentation, the patient had a slightly reduced general condition and moderately enlarged mandibular and popliteal lymph nodes. The initial...

  • Case Report
  • Open Access
2 Citations
3,112 Views
10 Pages

Renal Replacement Therapy in Methylmalonic Aciduria-Related Metabolic Failure: Case Report and Literature Review

  • Giovanni Pintus,
  • Nicola Vitturi,
  • Gianni Carraro,
  • Livia Lenzini,
  • Giorgia Gugelmo,
  • Ilaria Fasan,
  • Alberto Madinelli,
  • Alberto Burlina,
  • Angelo Avogaro and
  • Lorenzo Arcangelo Calò

23 July 2024

Background: Methylmalonic Aciduria (MA) without homocystinuria (or isolated MA) is a group of rare inherited metabolic disorders which leads to the accumulation of methylmalonic acid (MMA), a toxic molecule that accumulates in blood, urine, and cereb...

  • Article
  • Open Access
9 Citations
3,463 Views
22 Pages

SARS-CoV-2 mRNA Vaccine-Induced Cellular and Humoral Immunity in Hemodialysis Patients

  • Ewa Kwiatkowska,
  • Krzysztof Safranow,
  • Iwona Wojciechowska-Koszko,
  • Paulina Roszkowska,
  • Violetta Dziedziejko,
  • Marek Myślak,
  • Jacek Różański,
  • Kazimierz Ciechanowski,
  • Tomasz Stompór and
  • Leszek Domański
  • + 6 authors

Background/Aims: Chronic kidney disease CKD patients on intermittent hemodialysis IHD are exposed to SARS-CoV-2 infection and carry a risk of developing severe symptoms. The aim of this study was to evaluate the humoral and cellular immunity induced...

  • Article
  • Open Access
2 Citations
3,660 Views
12 Pages

Clinical Outcomes of Trimethoprim/Sulfamethoxazole in Critically Ill Patients with Stenotrophomonas maltophilia Bacteremia and Pneumonia Utilizing Renal Replacement Therapies

  • Wasim S. El Nekidy,
  • Khaled Al Zaman,
  • Emna Abidi,
  • Diaa Alrahmany,
  • Islam M. Ghazi,
  • Rania El Lababidi,
  • Mohamad Mooty,
  • Fadi Hijazi,
  • Muriel Ghosn and
  • Jihad Mallat
  • + 4 authors

14 April 2024

Background: The clinical outcomes of usual doses of Trimethoprim–sulfamethoxazole (TMP/SMZ) for treating S. maltophilia in critically ill patients on renal replacement therapies (RRT) have not been established. We sought to assess the clinical...