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17 Results Found

  • Article
  • Open Access
12 Citations
3,735 Views
9 Pages

Velvet Antler Production and Hematological Changes in Male Sika Deers Fed with Spent Mushroom Substrate

  • Chongshan Yuan,
  • Min Wu,
  • Syed Muhammad Tahir,
  • Xinyuan Chen,
  • Changze Li,
  • Aiwu Zhang and
  • Wenfa Lu

30 June 2022

At present, spent mushroom substrate (SMS) is a waste resource that is producing a pollution problem in China, and which has some use as animal feed or fertilizer, has not been assessed as a feed for deer. The purpose of this study is to expand the f...

(This article belongs to the Collection Novel Animal Feeds, Forage Crops, and Cultivation Strategies for Enhancing Livestock Nutrition and Ecosystem Services)
  • Case Report
  • Open Access
2 Citations
15,115 Views
8 Pages

A Case of XX Disorder of Sexual Development in a Female-Phenotype Roe Deer (Capreolus capreolus L.) Associated with Antlers Growth with Retained Velvet

  • Filipe Silva,
  • Isabel Pires,
  • Justina Prada,
  • Miguel Queirós,
  • Aurora Monzón,
  • José Almeida,
  • Roberto Sargo,
  • Filipa Loureiro,
  • Luís Sousa and
  • Isabel Dias
  • + 5 authors

29 March 2022

A 3-to-4-year-old roe deer (Capreolus capreolus L.) was admitted to the Veterinary Hospital. Although it showed well-developed antlers with retained velvet, an external female appearance and genitalia were evident. External biometrical measurements w...

(This article belongs to the Special Issue Wildlife Diseases)
  • Article
  • Open Access
5 Citations
3,424 Views
20 Pages

MiRNA Profiling and Its Potential Roles in Rapid Growth of Velvet Antler in Gansu Red Deer (Cervus elaphus kansuensis)

  • Zhenxiang Zhang,
  • Caixia He,
  • Changhong Bao,
  • Zhaonan Li,
  • Wenjie Jin,
  • Changzhong Li and
  • Yanxia Chen

7 February 2023

A significant variety of cell growth factors are involved in the regulation of antler growth, and the fast proliferation and differentiation of various tissue cells occur during the yearly regeneration of deer antlers. The unique development process...

(This article belongs to the Section Animal Genetics and Genomics)
  • Article
  • Open Access
2 Citations
1,596 Views
26 Pages

Research on the Therapeutic Effect and Mechanism of Stir-Roasted Deer Velvet Antler with Ghee on Non-Alcoholic Fatty Liver Disease

  • Xuan He,
  • Yinghan Liu,
  • Shuning Cui,
  • Zhenming Yu,
  • Zhongmei He,
  • Ying Zong,
  • Weijia Chen,
  • Jianan Geng,
  • Jia Zhou and
  • Hongbo Teng
  • + 2 authors

26 January 2026

Objectives: This study aims to explore the therapeutic effect and mechanism of stir-roasted deer velvet antler with ghee (ZLR) on Non-Alcoholic Fatty Liver Disease (NAFLD). Methods: This study used proteomics to analyze the protein composition of roa...

(This article belongs to the Section Nutrition and Metabolism)
  • Article
  • Open Access
16 Citations
4,496 Views
17 Pages

Sika Deer Velvet Antler Peptide Exerts Neuroprotective Effect in a Parkinson’s Disease Model via Regulating Oxidative Damage and Gut Microbiota

  • Ying Liu,
  • Hongyuan Li,
  • Min Yang,
  • Jia Guo,
  • Zepeng Sun,
  • Shuyue Wang,
  • Ru Li,
  • Xin Pang,
  • Yumi Kim and
  • Yinghua Peng
  • + 1 author

Parkinson’s disease (PD) is the second most common neurodegenerative disorder globally. Recognizing the potential of velvet antler in the nervous system, as shown in numerous studies, this research was aimed at evaluating the neuroprotective ef...

(This article belongs to the Section Pharmacology)
  • Article
  • Open Access
9 Citations
4,469 Views
21 Pages

Velvet antler is a precious traditional Chinese medicine used for thousands of years. This study investigated the anti-colitis effects of water extracts of Formosan sambar deer (SVAE) and red deer (RVAE) to identify the possible mechanisms and the bi...

(This article belongs to the Section Molecular and Translational Medicine)
  • Article
  • Open Access
5 Citations
3,168 Views
25 Pages

The Effects of Sika Deer Antler Peptides on 3T3-L1 Preadipocytes and C57BL/6 Mice via Activating AMPK Signaling and Gut Microbiota

  • Tong Sun,
  • Zezhuang Hao,
  • Fanying Meng,
  • Xue Li,
  • Yihua Wang,
  • Haowen Zhu,
  • Yong Li and
  • Yuling Ding

(1) Background: To explore the anti-obesity effects and mechanisms of sika deer velvet antler peptides (sVAP) on 3T3-L1 preadipocytes and in high-fat diet (HFD)-induced obese mice. (2) Methods: sVAP fractions of different molecular weights were obtai...

  • Article
  • Open Access
5 Citations
2,345 Views
27 Pages

4 September 2025

Deer antler-derived medicinal materials, including antler velvet, antlers, and deer antler base, exhibit differential therapeutic efficacy across developmental stages, though their molecular mechanisms at the proteomic level remain uncharacterized. T...

  • Article
  • Open Access
6 Citations
3,048 Views
14 Pages

Integrated Transcriptomic and Proteomic Analyses of Antler Growth and Ossification Mechanisms

  • Ruijia Liu,
  • Pan Zhang,
  • Jiade Bai,
  • Zhenyu Zhong,
  • Yunfang Shan,
  • Zhibin Cheng,
  • Qingxun Zhang,
  • Qingyun Guo,
  • Hao Zhang and
  • Bo Zhang

9 December 2024

Antlers are the sole mammalian organs capable of continuous regeneration. This distinctive feature has evolved into various biomedical models. Research on mechanisms of antler growth, development, and ossification provides valuable insights for limb...

(This article belongs to the Section Molecular Informatics)
  • Article
  • Open Access
5 Citations
4,634 Views
13 Pages

Pressure Algometry Validation and Determination of Efficacy of Articaine Hydrochloride Ring Block in Antler Removal in Red Deer (Cervus elaphus)

  • Farzin Sahebjam,
  • Kavitha Kongara,
  • John Paul Chambers,
  • Ruth Ellen Walker,
  • Rafea Naffa,
  • Nicolas Lopez-Villalobos and
  • Preet Mohinder Singh

3 November 2020

New Zealand deer farming centres on the production of meat and velvet antler. Velvet antler removal is a painful procedure and currently, New Zealand Animal Welfare regulations dictate surgical removal of velvet antlers under lignocaine anaesthesia....

(This article belongs to the Special Issue Advances in the Use of Therapeutic Drugs for Improved Animal Welfare)
  • Article
  • Open Access
8 Citations
7,961 Views
22 Pages

General Direct Anticancer Effects of Deer Growing Antler Extract in Several Tumour Cell Lines, and Immune System-Mediated Effects in Xenograft Glioblastoma

  • Alessandra Rossetti,
  • Louis Chonco,
  • Nicolas Alegría,
  • Veronica Zelli,
  • Andrés J. García,
  • Carmen Ramírez-Castillejo,
  • Alessandra Tessitore,
  • Carlos de Cabo,
  • Tomás Landete-Castillejos and
  • Claudio Festuccia

Deer antlers are the fastest growing tissue. Because they are based on proto-oncogenes, to avoid the risk of cancer, antlers evolved strong anticancer mechanisms, and thus their extract (DVA) is effective also against the few human tumours studied so...

(This article belongs to the Topic Antitumor Activity of Natural Products and Related Compounds—2nd Edition)
  • Article
  • Open Access
1,082 Views
16 Pages

Genome-Wide Identification of Candidate Genes Associated with Antler Weight in Tahe Red Deer

  • Zhengchuang Hou,
  • Yujiao Qi,
  • Chenchen Yang,
  • Junjie Shao,
  • Faling Hou,
  • Wenxi Qian,
  • Qinghua Gao and
  • Chunmei Han

7 May 2026

The Tahe red deer is derived from the wild Tarim red deer, an endemic subspecies native to the Tarim Basin in Xinjiang, China. It has recently received official approval as a locally bred deer variety, developed through artificial breeding programs....

(This article belongs to the Section Animal Genetics and Genomics)
  • Article
  • Open Access
15 Citations
2,917 Views
16 Pages

The aim of this experiment was to study the effects of different selenium supplemental levels on rumen fermentation microflora of sika deer at the velvet antler growth stage. A total of 20 5-year-old, healthy sika deer at the velvet antler growth sta...

(This article belongs to the Section Gut Microbiota)
  • Article
  • Open Access
2 Citations
3,232 Views
13 Pages

Characteristics and Differences in the Antler Velvet Microbiota During Regeneration

  • Yongxiang Li,
  • Yuhang Zhu,
  • Bo Yang,
  • Shaochen Yu,
  • Songze Li,
  • André-Denis G. Wright,
  • Rui Du,
  • Huazhe Si and
  • Zhipeng Li

The skin surface has a complex and dynamic ecosystem inhabited by a diverse microbiota. The wound formed by antler velvet shedding can naturally achieve regenerative restoration, but the changes in microbial composition that occur during antler velve...

(This article belongs to the Special Issue Omics Research in Microbial Ecology)
  • Article
  • Open Access
707 Views
23 Pages

9 April 2026

Previous studies on velvet antler processing have mainly evaluated single techniques, and systematic comparisons of processing combinations are limited. This study investigated the effects of different processing combinations on the nutritional compo...

(This article belongs to the Section Food Process Engineering)
  • Article
  • Open Access
2 Citations
3,479 Views
16 Pages

Genetic Diversity and Population Structure in Captive Populations of Formosan Sambar Deer (Rusa unicolor swinhoei)

  • Hsiao-Mei Liang,
  • Kuo-Tai Yang,
  • Yu-Tzu Cheng,
  • Shen-Chang Chang,
  • Cheng-Yung Lin,
  • Ming-Yang Tsai,
  • Der-Yuh Lin and
  • Kuo-Hsiang Hung

5 October 2023

Formosan sambar deer (Rusa unicolor swinhoei) are of great economic significance in Taiwan, resulting in a substantial increase in deer farming to meet the high demand for velvet antlers. Inbreeding depression and reduced genetic variability can lead...

(This article belongs to the Special Issue Genetic Resources in Livestock and Fish: Management and Conservation Strategies)
  • Article
  • Open Access
3 Citations
2,643 Views
9 Pages

Hematological Changes in Sika Doe and Suckling Fawn Fed with Spent Mushroom Substrate of Pleurotus ostreatus

  • Chongshan Yuan,
  • Changze Li,
  • Xinyuan Chen,
  • Syed Muhammad Tahir,
  • Aiwu Zhang and
  • Min Wu

5 August 2022

Sika deer velvet antler is the most important animal nutraceutic in traditional Chinese medicine. Reducing the breeding cost of sika deer by looking for a low-cost diet is the main research direction at present. The purpose of this experiment was to...

(This article belongs to the Collection Novel Animal Feeds, Forage Crops, and Cultivation Strategies for Enhancing Livestock Nutrition and Ecosystem Services)