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25 Results Found

  • Article
  • Open Access
2 Citations
2,274 Views
12 Pages

21 May 2023

This investigation is motivated by interest in nanostructured FeOOH anodes for aqueous asymmetric supercapacitors operating in Na2SO4 electrolyte. The research goal is the fabrication of anodes with high active mass loading of 40 mg cm−2, high...

  • Article
  • Open Access
1 Citations
1,397 Views
23 Pages

Background: Aneratrigine, a potent selective Nav1.7 inhibitor, faced challenges in developing a clinically viable oral formulation due to its poor aqueous solubility in acidic gastric conditions (0.06 mg/mL at pH 1.2), leading to limited bioavailabil...

  • Review
  • Open Access
2 Citations
2,251 Views
15 Pages

How Does Cancer Occur? How Should It Be Treated? Treatment from the Perspective of Alkalization Therapy Based on Science-Based Medicine

  • Reo Hamaguchi,
  • Masahide Isowa,
  • Ryoko Narui,
  • Hiromasa Morikawa,
  • Toshihiro Okamoto and
  • Hiromi Wada

26 September 2024

This review article investigates the relationship between mitochondrial dysfunction and cancer progression, emphasizing the metabolic shifts that promote tumor growth. Mitochondria are crucial for cellular energy production, but they also play a sign...

  • Feature Paper
  • Article
  • Open Access
2 Citations
1,312 Views
21 Pages

Sustainable PLA Composites Filled with Poaceae Fibers: Thermal, Structural, and Mechanical Properties

  • Natalia Kubiak,
  • Bogna Sztorch,
  • Magdalena Kustosz,
  • Miłosz Frydrych,
  • Daria Pakuła,
  • Marek Jałbrzykowski,
  • Tobias Hartmann,
  • Camilo Zopp,
  • Lothar Kroll and
  • Robert E. Przekop

23 August 2025

The present study investigates the manufacturing and characterization of poly(lactic acid) (PLA)-based composites with raw and treated Poaceae, with loadings of 5, 10, and 20% wt. Before composite fabrication, the lignocellulosic fillers were analyze...

  • Article
  • Open Access
2 Citations
1,585 Views
13 Pages

13 December 2024

Background. Acetyl phosphate (AcP) is a microbial intermediate involved in the central bacterial metabolism. In bacteria, it also functions as a donor of acetyl and phosphoryl groups in the nonenzymatic protein acetylation and signal transduction. In...

  • Article
  • Open Access
1 Citations
5,924 Views
18 Pages

Potassium/Sodium Citrate Attenuates Paclitaxel-Induced Peripheral Neuropathy

  • Daisuke Uta,
  • Hideki Nakamura,
  • Kengo Maruo,
  • Kanoko Matsumura,
  • Yohei Usami and
  • Toshiaki Kume

Chemotherapy-induced peripheral neuropathy (CIPN) is a significant adverse event with unclear mechanisms and limited treatment alternatives. This study aimed to investigate the efficacy of two alkalizing agents, a mixture of potassium citrate and sod...

  • Review
  • Open Access
99 Citations
65,403 Views
17 Pages

Types of Hair Dye and Their Mechanisms of Action

  • Simone Aparecida Da França,
  • Michelli Ferrera Dario,
  • Victoria Brigatto Esteves,
  • André Rolim Baby and
  • Maria Valéria Robles Velasco

22 April 2015

Hair color change by dye application is a common procedure among women. Hair dyes are classified, according to color resistance, into temporary, semipermanent, demipermanent and permanent. The first two are based on molecules which are already colore...

  • Article
  • Open Access
7 Citations
2,969 Views
23 Pages

Formulation and Evaluation of pH-Modulated Amorphous Solid Dispersion-Based Orodispersible Tablets of Cefdinir

  • Yahya Alhamhoom,
  • Thanusha Kumaraswamy,
  • Avichal Kumar,
  • Shivakumar Hagalavadi Nanjappa,
  • Sanjana S. Prakash,
  • Mohamed Rahamathulla,
  • Kamal Y. Thajudeen,
  • Mohammed Muqtader Ahmed and
  • Thippeswamy Boreddy Shivanandappa

Cefdinir (CEF) is a semi-synthetic third-generation broad-spectrum oral cephalosporin that exhibits poor solubility at lower pH values. Considering this, pH-modulated CEF solid dispersions (ASDs) were produced by solvent evaporation method employing...

  • Article
  • Open Access
5 Citations
3,021 Views
15 Pages

Structural Transformations of Hydrolysates Obtained from Ti-, Zr-, and Ti, Zr-Solutions Used for Clay Pillaring: Towards Understanding of the Mixed Pillars Nature

  • Krzysztof Bahranowski,
  • Agnieszka Klimek,
  • Adam Gaweł,
  • Katarzyna Górniak,
  • Alicja Michalik and
  • Ewa Serwicka-Bahranowska

24 December 2018

Structural characteristics of hydrolysates formed from the aqueous Ti-, Zr-, and Ti, Zr-pillaring solutions prepared from inorganic precursors (TiCl4 and ZrOCl2), was investigated and compared with that of precipitates obtained from the same solution...

  • Review
  • Open Access
62 Citations
9,508 Views
42 Pages

Froth Flotation of Chalcopyrite/Pyrite Ore: A Critical Review

  • César I. Castellón,
  • Norman Toro,
  • Edelmira Gálvez,
  • Pedro Robles,
  • Williams H. Leiva and
  • Ricardo I. Jeldres

21 September 2022

In the present work an intense bibliographic search is developed, with updated information on the microscopic fundamentals that govern the behavior of flotation operations of chalcopyrite, the main copper mineral in nature. In particular, the effect...

  • Article
  • Open Access
12 Citations
2,903 Views
17 Pages

Low-Calcium, Porous, Alkali-Activated Materials as Novel pH Stabilizers for Water Media

  • Laura Vitola,
  • Diana Bajare,
  • Angel Palomo and
  • Ana Fernandez-Jimenez

22 October 2020

Due to the increase of water consumption, water treatment systems become more actual and innovative materials for water treatment are welcomed. Traditionally, alkalizing agents, such as lime or caustic soda, have been employed to increase the pH leve...

  • Article
  • Open Access
9 Citations
5,558 Views
18 Pages

Enhancing Dissolution and Oral Bioavailability of Ursodeoxycholic Acid with a Spray-Dried pH-Modified Extended Release Formulation

  • Jaehyeok Lee,
  • Chul Haeng Lee,
  • Jong-Geon Lee,
  • So Yeon Jeon,
  • Min-Koo Choi and
  • Im-Sook Song

Ursodeoxycholate (UDCA) has low oral bioavailability and pH-dependent solubility and permeability. Thus, we developed a pH-modified extended-release formulation of UDCA using Na2CO3 as the alkalizing agent and hydroxypropyl methylcellulose (HPMC) as...

  • Article
  • Open Access
9 Citations
2,724 Views
13 Pages

Keratinolytic fungi representing the genus Arthroderma that were isolated from the soils of a rook (Corvus frugilegus) colony were used as biological agents for the disposal of waste feathers. The aim of this study was to assess the abilities of Arth...

  • Feature Paper
  • Article
  • Open Access
14 Citations
3,136 Views
9 Pages

Relationship between Phase Composition and Mechanical Properties of Peat Soils Stabilized Using Oil Shale Ash and Pozzolanic Additive

  • Ergo Rikmann,
  • Ivar Zekker,
  • Tõnis Teppand,
  • Vello Pallav,
  • Merrit Shanskiy,
  • Uno Mäeorg,
  • Toomas Tenno,
  • Juris Burlakovs and
  • Jüri Liiv

30 March 2021

Construction of road embankments in peatlands commonly involves replacement of the peat with a fill-up soil of an adequate load-bearing capacity. This usually requires a lowering of the water level, turning a peatland from a carbon sink to a source o...

  • Article
  • Open Access
11 Citations
5,708 Views
20 Pages

Newfangled Topical Film-Forming Solution for Facilitated Antifungal Therapy: Design, Development, Characterization, and In Vitro Evaluation

  • Bhakti Dhimmar,
  • Rahul Pokale,
  • Mohamed Rahamathulla,
  • Umme Hani,
  • Mohammad Y. Alshahrani,
  • Sultan Alshehri,
  • Faiyaz Shakeel,
  • Prawez Alam,
  • Riyaz Ali M. Osmani and
  • Amit B. Patil

17 February 2023

Luliconazole is a broad-spectrum topical antifungal agent that acts by altering the synthesis of fungi cell membranes. Literature suggests that the recurrence of fungal infection can be avoided by altering the pH of the site of infection. Studies hav...

  • Article
  • Open Access
11 Citations
3,380 Views
16 Pages

8 January 2022

Enterovirus 71 (EV71) is an etiological agent of hand foot and mouth disease and can also cause neurological complications in young children. However, there are no approved drugs as of yet to treat EV71 infections. In this study, we conducted antivir...

  • Article
  • Open Access
3 Citations
2,147 Views
15 Pages

Water Chemistry Impact on Activated Corrosion Products: An Assessment on Tokamak Reactors

  • Martina Molinari,
  • Matteo D’Onorio,
  • Giovanni Mariano,
  • Nicholas Terranova and
  • Gianfranco Caruso

15 June 2023

Activated Corrosion Product (ACP) formation and deposition pose a critical safety issue for nuclear fusion reactors. The working fluid transports the ACPs towards regions accessible by worker personnel, i.e., the steam generator. The code OSCAR-Fusio...

  • Review
  • Open Access
5 Citations
11,279 Views
12 Pages

Recent Advances in the Diagnosis and Management of Retrograde Ejaculation: A Narrative Review

  • Charalampos Konstantinidis,
  • Athanasios Zachariou,
  • Evangelini Evgeni,
  • Selahittin Çayan,
  • Luca Boeri and
  • Ashok Agarwal

Retrograde ejaculation (RE) is a condition where the forward expulsion of seminal fluid is impaired, leading to infertility and psychological distress in affected individuals. This narrative review examines the etiology, pathophysiology, diagnosis, a...

  • Article
  • Open Access
8 Citations
4,776 Views
21 Pages

Multi-Elemental Analysis of Hair and Fingernails Using Energy-Dispersive X-ray Fluorescence (ED XRF) Method Supported by Inductively Coupled Plasma Mass Spectrometry (ICP MS)

  • Zofia Mierzyńska,
  • Maria Niemirska,
  • Kacper Zgonina,
  • Tomasz Bieńkowski,
  • Krzysztof Hryniów,
  • Paweł Świder and
  • Katarzyna Pawlak

7 February 2024

This work compared the multi-element analysis of human hair and nails using inductively coupled plasma mass spectrometry (ICP MS) with an easy, fast, cheap, non-destructive method using energy-dispersive x-ray fluorescence (ED XRF). The ICP MS-based...

  • Article
  • Open Access
23 Citations
5,946 Views
10 Pages

The Impact of Diet on Urinary Risk Factors for Cystine Stone Formation

  • Roswitha Siener,
  • Norman Bitterlich,
  • Hubert Birwé and
  • Albrecht Hesse

6 February 2021

Despite the importance of dietary management of cystinuria, data on the contribution of diet to urinary risk factors for cystine stone formation are limited. Studies on the physiological effects of diet on urinary cystine and cysteine excretion are l...

  • Article
  • Open Access
14 Citations
3,084 Views
15 Pages

Facile One-Pot Green Synthesis of Magneto-Luminescent Bimetallic Nanocomposites with Potential as Dual Imaging Agent

  • Radek Ostruszka,
  • Denisa Půlpánová,
  • Tomáš Pluháček,
  • Ondřej Tomanec,
  • Petr Novák,
  • Daniel Jirák and
  • Karolína Šišková

13 March 2023

Nanocomposites serving as dual (bimodal) probes have great potential in the field of bio-imaging. Here, we developed a simple one-pot synthesis for the reproducible generation of new luminescent and magnetically active bimetallic nanocomposites. The...

  • Communication
  • Open Access
760 Views
10 Pages

Groundwater at petroleum-contaminated sites typically exhibits elevated dissolved inorganic carbon (DIC) levels due to hydrocarbon biodegradation; however, our prior field investigations revealed an enigmatic DIC depletion anomaly that starkly contra...

  • Article
  • Open Access
1,110 Views
17 Pages

Phosphogypsum Processing into Innovative Products of High Added Value

  • Daniil I. Monastyrsky,
  • Marina A. Kulikova,
  • Marina A. Egorova,
  • Nina P. Shabelskaya,
  • Oleg A. Medennikov,
  • Asatullo M. Radzhabov,
  • Yuliya A. Gaidukova and
  • Vera A. Baranova

7 July 2025

The paper presents a comprehensive study of the processing possibilities for phosphogypsum, a large-tonnage chemical industry waste, into highly sought-after products, such as ultraviolet pigments, and alkalizing reagents for the preparation of organ...

  • Article
  • Open Access
6 Citations
3,076 Views
11 Pages

24 December 2021

High efficiency slime water settlement is very important for ensuring washing water recycling in coal preparation plants. In order to improve the sedimentation of coal slime water, an iron ion-based coagulant was prepared by titanium ion complexation...

  • Review
  • Open Access
43 Citations
7,308 Views
15 Pages

Impact of Hyper- and Hypo-Uricemia on Kidney Function

  • Junichiro Miake,
  • Ichiro Hisatome,
  • Katsuyuki Tomita,
  • Tadahiro Isoyama,
  • Shinobu Sugihara,
  • Masanari Kuwabara,
  • Kazuhide Ogino and
  • Haruaki Ninomiya

Uric acid (UA) forms monosodium urate (MSU) crystals to exert proinflammatory actions, thus causing gout arthritis, urolithiasis, kidney disease, and cardiovascular disease. UA is also one of the most potent antioxidants that suppresses oxidative str...