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30 Results Found

  • Article
  • Open Access
42 Citations
4,947 Views
18 Pages

Characterization of Phenolic Compounds and Antiproliferative Effects of Salvia pomifera and Salvia fruticosa Extracts

  • Antonios Koutsoulas,
  • Martina Čarnecká,
  • Jiří Slanina,
  • Jaroslav Tóth and
  • Iva Slaninová

12 August 2019

The phenolic compounds of methanolic extracts of Salvia pomifera and Salvia fruticosa were identified by liquid chromatography tandem mass spectrometry. Carnosic acid and its metabolite carnosol were the most abundant terpene phenolic compounds of S....

  • Article
  • Open Access
9 Citations
4,099 Views
14 Pages

Chemical and Biological Characterization of the Anticancer Potency of Salvia fruticosa in a Model of Human Malignant Melanoma

  • Sotiris Kyriakou,
  • Venetia Tragkola,
  • Michael Plioukas,
  • Ioannis Anestopoulos,
  • Paschalina S. Chatzopoulou,
  • Eirini Sarrou,
  • Dimitrios T. Trafalis,
  • Maria V. Deligiorgi,
  • Rodrigo Franco and
  • Mihalis I. Panayiotidis
  • + 1 author

16 November 2021

Malignant melanoma is one of the most aggressive types of skin cancer with an increasing incidence worldwide. Thus, the development of innovative therapeutic approaches is of great importance. Salvia fruticosa (SF) is known for its anticancer propert...

  • Article
  • Open Access
12 Citations
3,077 Views
12 Pages

13 June 2020

Salvia fruticosa Miller, also known as Cretan or Greek sage, is a medicinal plant with significant biological properties, which are largely ascribed to its polyphenolic composition, but there is to-date a scarcity of green and sustainable processes f...

  • Article
  • Open Access
7 Citations
2,921 Views
19 Pages

Chemical Profiling and Antioxidant and Anti-Amyloid Capacities of Salvia fruticosa Extracts from Greece

  • Antonis Ververis,
  • Sotiris Kyriakou,
  • Kristia Ioannou,
  • Paschalina S. Chatzopoulou,
  • Mihalis I. Panayiotidis,
  • Michael Plioukas and
  • Kyproula Christodoulou

6 September 2023

An increasingly common ailment in elderly persons is Alzheimer’s disease (AD), a neurodegenerative illness. Present treatment is restricted to alleviating symptoms; hence, there is a requirement to develop an effective approach to AD treatment....

  • Article
  • Open Access
10 Citations
3,994 Views
18 Pages

Chemical Characterization and Antioxidant, Antibacterial, Antiacetylcholinesterase and Antiproliferation Properties of Salvia fruticosa Miller Extracts

  • Michella Dawra,
  • Jalloul Bouajila,
  • Marc El Beyrouthy,
  • Alain Abi Rizk,
  • Patricia Taillandier,
  • Nancy Nehme and
  • Youssef El Rayess

The Salvia fruticosa (Mill.) is the most medicinal plant used in Lebanon. The aim of this study is to investigate the phytochemical composition and the biological activities (in vitro) of its extracts. The plant was extracted by cold maceration with...

  • Article
  • Open Access
6 Citations
2,410 Views
16 Pages

Chemical Composition of Salvia fruticosa Mill. Essential Oil and Its Protective Effects on Both Photosynthetic Damage and Oxidative Stress in Conocephalum conicum L. Induced by Environmental Heavy Metal Concentrations

  • Natale Badalamenti,
  • Giovanna Salbitani,
  • Piergiorgio Cianciullo,
  • Rosanna Bossa,
  • Francesca De Ruberto,
  • Valeria Greco,
  • Adriana Basile,
  • Viviana Maresca,
  • Maurizio Bruno and
  • Simona Carfagna

11 November 2023

The genus Salvia L., belonging to the Lamiaceae family, contains more than 900 species distributed in various parts of the world. It is a genus containing aromatic plants used both in the culinary field and above all in the cosmetic area to produce s...

  • Article
  • Open Access
3 Citations
1,623 Views
16 Pages

Environmentally Friendly Microemulsions of Essential Oils of Artemisia annua and Salvia fruticosa to Protect Crops against Fusarium verticillioides

  • Lucia Grifoni,
  • Cristiana Sacco,
  • Rosa Donato,
  • Spyros Tziakas,
  • Ekaterina-Michaela Tomou,
  • Helen Skaltsa,
  • Giulia Vanti,
  • Maria Camilla Bergonzi and
  • Anna Rita Bilia

27 October 2024

Essential oils (EOs) are reported to be natural pesticides, but their use to protect crops is very limited due to EOs’ high instability and great volatility. Nanovectors represent a very smart alternative, and in this study, EOs from Artemisia...

  • Feature Paper
  • Article
  • Open Access
15 Citations
3,323 Views
15 Pages

11 July 2020

A series of citrate salts were tested as hydrogen bond acceptors to synthesize deep eutectic solvents (DES) based on lactic acid and glycerol, used as hydrogen bond donors. The DES produced were then screened to identify the highest performing system...

  • Article
  • Open Access
21 Citations
3,784 Views
20 Pages

21 February 2023

The essential oil production of Salvia fruticosa L. generates considerable amounts of post-distillation solid residues (PRES) which are rich in phenolic compounds. In the present work, the recovery of phenolic antioxidants from PRES by using Microwav...

  • Article
  • Open Access
15 Citations
3,588 Views
19 Pages

Hybrids Development between Greek Salvia Species and Their Drought Resistance Evaluation along with Salvia fruticosa, under Attapulgite-Amended Substrate

  • Maria Papafotiou,
  • Aikaterini N. Martini,
  • Eleonora Papanikolaou,
  • Eleftherios G. Stylias and
  • Anastasios Kalantzis

25 November 2021

Aiming to obtain Salvia hybrids with ornamental value and high drought resistance, for xeriscaping, crossbreeding was made with Greek Salvia species. S. fruticosa and S. officinalis when used as seed parent were successfully crossed with S. pomifera...

  • Feature Paper
  • Article
  • Open Access
15 Citations
3,188 Views
16 Pages

16 May 2020

S. fruticosa, collectively known as Cretan sage, is a medicinal plant to which a number of bioactivities have been attributed. In spite of its importance in nutrition and pharmacy, reports on the extraction of major polyphenols using sustainable proc...

  • Article
  • Open Access
22 Citations
2,661 Views
16 Pages

Acclimatization of Mediterranean Native Sages (Salvia spp.) and Interspecific Hybrids in an Urban Green Roof under Regular and Reduced Irrigation

  • Maria Papafotiou,
  • Aikaterini N. Martini,
  • Lamprini Tassoula,
  • Eleftherios G. Stylias,
  • Anastasios Kalantzis and
  • Eleftherios Dariotis

21 April 2022

Native-to-Greece sage species, namely, Salvia fruticosa, S. officinalis, S. pomifera ssp. pomifera, S. ringens, S. tomentosa and interspecific hybrids, were evaluated for their acclimatization in an extensive Mediterranean green roof during summer un...

  • Article
  • Open Access
60 Citations
5,760 Views
18 Pages

Arbuscular Mycorrhizal Symbiosis Enhances Photosynthesis in the Medicinal Herb Salvia fruticosa by Improving Photosystem II Photochemistry

  • Michael Moustakas,
  • Gülriz Bayçu,
  • Ilektra Sperdouli,
  • Hilal Eroğlu and
  • Eleftherios P. Eleftheriou

30 July 2020

We investigated the influence of Salvia fruticosa colonization by the arbuscular mycorrhizal fungi (AMF) Rhizophagus irregularis on photosynthetic function by using chlorophyll fluorescence imaging analysis to evaluate the light energy use in photosy...

  • Article
  • Open Access
4 Citations
3,304 Views
21 Pages

28 January 2024

The objective of this study was the optimization of the extraction process and the qualitative and quantitative determination of the bioactive metabolites: 12-O-methylcarnosic acid (12MCA), carnosic acid (CA), carnosol (CS), 7-O-methyl-epi-rosmanol (...

  • Article
  • Open Access
19 Citations
5,344 Views
28 Pages

Sages are medicinal and aromatic plants that constitute a large pool from which active compounds of great pharmaceutical potential can be derived, while at the same time, they also have ornamental value. The purpose of this study was to develop the m...

  • Article
  • Open Access
1,969 Views
16 Pages

Cytotoxic Activity of Essential Oils from Middle Eastern Medicinal Plants on Malignant Keratinocytes

  • Rima Othman,
  • Vanessa Moarbes,
  • Muriel Tahtouh Zaatar,
  • Diane Antonios,
  • Rabih Roufayel,
  • Marc Beyrouthy,
  • Ziad Fajloun,
  • Jean-Marc Sabatier and
  • Marc Karam

Skin cancer, including melanoma and non-melanoma cancers (basal and squamous cell carcinomas), is the most common type of cancer. UV radiation, family history, and genetic predisposition are the main risk factors. Although surgical excision is the st...

  • Article
  • Open Access
2,525 Views
26 Pages

Unveiling the Genomic Basis of Antagonism and Plant Growth Promotion in the Novel Endophyte Bacillus velezensis Strain B.B.Sf.2

  • Dimitra Douka,
  • Tasos-Nektarios Spantidos,
  • Panagiotis Katinakis and
  • Anastasia Venieraki

4 May 2025

Background/Objectives: The agriculture sector faces significant challenges due to global climate change, environmental stressors, and rapid population growth, compounded by unsustainable farming practices. This study investigates the potential of the...

  • Article
  • Open Access
32 Citations
7,513 Views
17 Pages

The Assessment of Antimicrobial and Anti-Biofilm Activity of Essential Oils against Staphylococcus aureus Strains

  • Caglar Ersanli,
  • Athina Tzora,
  • Ioannis Skoufos,
  • Konstantina Fotou,
  • Eleni Maloupa,
  • Katerina Grigoriadou,
  • Chrysoula (Chrysa) Voidarou and
  • Dimitrios I. Zeugolis

13 February 2023

The increase in antimicrobial resistance and tolerance over the years has become a serious public health problem, leading to the inevitable development of alternative antimicrobial agents as substitutes for industrial pharmaceutical antibiotics targe...

  • Article
  • Open Access
49 Citations
4,636 Views
18 Pages

Comparative Antioxidant, Anti-Acetylcholinesterase and Anti-α-Glucosidase Activities of Mediterranean Salvia Species

  • Mateja Mervić,
  • Maja Bival Štefan,
  • Marija Kindl,
  • Biljana Blažeković,
  • Marijan Marijan and
  • Sanda Vladimir-Knežević

25 February 2022

Salvia species have a cosmopolitan distribution and comprise several well-known plants valuable for pharmaceutical and food industries due to their recognized medicinal, food flavouring, and preservative properties. The present study aimed to evaluat...

  • Article
  • Open Access
15 Citations
3,499 Views
18 Pages

22 December 2022

Salvia fruticosa and S. pomifera subsp. calycina are native to Eastern Mediterranean and S. pomifera subsp. pomifera is endemic to Greece. The primary aim of this study was to develop an analytical methodology for metabolomic profiling and to study t...

  • Article
  • Open Access
56 Citations
5,527 Views
20 Pages

18 March 2021

The study focused on the effects of ecology (plant communities and topographical data) on composition of essential oils (EOs) of some officinal wild plant species (Lamiales): Clinopodium suaveolens, Salvia fruticosa subsp. thomasii, Satureja montana...

  • Article
  • Open Access
1 Citations
1,377 Views
33 Pages

10 October 2025

Salvia fruticosa, S. officinalis, S. pomifera ssp. pomifera, S. ringens, and S. tomentosa have multiple potential uses in floriculture and the pharmaceutical industry, serving sustainable horticulture and landscaping. The aim was to develop effective...

  • Article
  • Open Access
10 Citations
3,767 Views
11 Pages

Structure and Function of the Soil Rhizosphere Fungal Communities in Medicinal Plants—A Preliminary Study

  • Itaii Applebaum,
  • Mareeswaran Jeyaraman,
  • Chen Sherman,
  • Tirza Doniger and
  • Yosef Steinberger

Plants regulate their rhizosphere microbiome, which partly comprises the fungal community. We conducted a study in order to determine the effect that five medicinal plant species (Origanum syriacum, Salvia fruticosa, Teucrium capitatum, Myrtus commun...

  • Article
  • Open Access
1,288 Views
16 Pages

1H-qNMR as a Tool for the Quantitative and Qualitative Evaluation of Abietane-Type Diterpenes in Lamiaceae Species Cultivated in Greece

  • Panagiotis Kallimanis,
  • Prokopios Magiatis,
  • Thalia Tsiaka,
  • Panagiotis Zoumpoulakis,
  • Angeliki Panagiotopoulou and
  • Ioanna Chinou

28 July 2025

This study aimed to quantitatively and qualitatively evaluate the content of carnosic acid (CA), 12-O-methyl-carnosic acid (12MCA), carnosol (CS), rosmanol (RO) and 7-O-methyl-epi-rosmanol (7MER) in 61 Lamiaceae plants growing in Greece, using 1H-qNM...

  • Article
  • Open Access
69 Citations
7,469 Views
18 Pages

Characterization and Antimicrobial Properties of Essential Oils from Four Wild Taxa of Lamiaceae Family Growing in Apulia

  • Francesca Valerio,
  • Giuseppe N. Mezzapesa,
  • Ahmed Ghannouchi,
  • Donato Mondelli,
  • Antonio F. Logrieco and
  • Enrico V. Perrino

18 July 2021

Four taxa of the Lamiaceae family growing in Apulia (Clinopodium suaveolens, Satureja montana subsp. montana, Thymbra capitata, and Salvia fruticosa subsp. thomasii) that had not been previously studied for their potential use in the food sector, wer...

  • Article
  • Open Access
16 Citations
6,263 Views
23 Pages

Phytochemical Profiles and Biological Activities of Plant Extracts from Aromatic Plants Cultivated in Cyprus

  • Antonios Chrysargyris,
  • Jovana D. Petrovic,
  • Ekaterina-Michaela Tomou,
  • Kalia Kyriakou,
  • Panayiota Xylia,
  • Andria Kotsoni,
  • Vasiliki Gkretsi,
  • Panagiota Miltiadous,
  • Helen Skaltsa and
  • Nikolaos Tzortzakis
  • + 1 author

15 January 2024

Medicinal and aromatic plants’ properties, still an interesting research area, are attributed to the presence of various specialized products that possess important pharmacological activities. In the present study, six medicinal/aromatic plants...

  • Article
  • Open Access
44 Citations
4,260 Views
17 Pages

Phytotoxic Effects of Essential Oils from Six Lamiaceae Species

  • Francesca Casella,
  • Maurizio Vurro,
  • Francesca Valerio,
  • Enrico Vito Perrino,
  • Giuseppe N. Mezzapesa and
  • Angela Boari

14 January 2023

Essential oils produced by plants, and their components, could be sources of new natural herbicidal compounds. Thirteen oils extracted from six wild Lamiaceae species (namely Clinopodium suaveolens (Sm.) Kuntze, Satureja montana L. subsp. montana, Th...

  • Article
  • Open Access
8 Citations
3,303 Views
13 Pages

Oral Supplementation with Hydroxytyrosol Synthesized Using Genetically Modified Escherichia coli Strains and Essential Oils Mixture: A Pilot Study on the Safety and Biological Activity

  • Yannis V. Simos,
  • Stelios Zerikiotis,
  • Panagiotis Lekkas,
  • Antrea-Maria Athinodorou,
  • Christianna Zachariou,
  • Christina Tzima,
  • Alexandros Assariotakis,
  • Dimitrios Peschos,
  • Konstantinos Tsamis and
  • Patra Vezyraki
  • + 8 authors

Several natural compounds have been explored as immune-boosting, antioxidant and anti-inflammatory dietary supplements. Amongst them, hydroxytyrosol, a natural antioxidant found in olive products, and endemic medicinal plants have attracted the scien...

  • Article
  • Open Access
7 Citations
1,579 Views
22 Pages

10 June 2024

Very little is known about the preservation and storage of fresh medicinal and aromatic plants (MAPs) and/or herbs. As with many leafy vegetables, i.e., lettuce, fresh spearmint is a very perishable product throughout the production line and requires...

  • Article
  • Open Access
6 Citations
1,986 Views
12 Pages

Soil Bacterial Community of Medicinal Plant Rhizosphere in a Mediterranean System

  • Yosef Steinberger,
  • Tirza Doniger,
  • Chen Sherman,
  • Mareeswaran Jeyaraman and
  • Itaii Applebaum

Several attempts have been made to evaluate the abundance and distribution of the bacterial community in the rhizosphere of medicinal plants. Many describe information based on an estimation of the community structure and the effects of plant cover i...