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82 Results Found

  • Article
  • Open Access
33 Citations
7,441 Views
12 Pages

29 February 2020

This study utilized radiographic comparative analysis in order to evaluate dimensional ridge changes four months after tooth extraction and immediate grafting with mineralized dentin particulate autograft and chopped platelet-rich fibrin. Fifty-eight...

  • Article
  • Open Access
17 Citations
3,603 Views
11 Pages

Replacement Process of Carbonate Apatite by Alveolar Bone in a Rat Extraction Socket

  • Xiaoxu Zhang,
  • Ikiru Atsuta,
  • Ikue Narimatsu,
  • Nobuyuki Ueda,
  • Ryosuke Takahashi,
  • Yuki Egashira,
  • Jing-Qi Zhang,
  • Jiong-Yan Gu,
  • Kiyoshi Koyano and
  • Yasunori Ayukawa

9 August 2021

The objective of this study was to investigate a bone graft substitute containing carbonate apatite (CO3Ap) to analyze bone replacement and the state of bone formation in vitro and in vivo compared with autogenous bone (AB) or control. An osteoclast...

  • Article
  • Open Access
3 Citations
3,144 Views
14 Pages

Prosthesis for missing maxillary molars with dental implants often requires maxillary sinus augmentation owing to insufficient alveolar bone height. However, the anatomical structure of the maxillary sinus is a significant risk factor. This study use...

  • Article
  • Open Access
2 Citations
2,416 Views
12 Pages

Biocompatibility of Subperiosteal Dental Implants: Changes in the Expression of Osteogenesis-Related Genes in Osteoblasts Exposed to Differently Treated Titanium Surfaces

  • Marco Roy,
  • Elisa Chelucci,
  • Alessandro Corti,
  • Lorenzo Ceccarelli,
  • Mauro Cerea,
  • Barbara Dorocka-Bobkowska,
  • Alfonso Pompella and
  • Simona Daniele

The use of endosseous dental implants may become unfeasible in the presence of significant maxillary bone atrophy; thus, surgical techniques have been proposed to promote bone regeneration in such cases. However, such techniques are complex and may e...

  • Article
  • Open Access
15 Citations
2,399 Views
13 Pages

Crestal and Subcrestal Placement of Morse Cone Implant–Abutment Connection Implants: An In Vitro Finite Element Analysis (FEA) Study

  • Luca Comuzzi,
  • Mario Ceddia,
  • Natalia Di Pietro,
  • Francesco Inchingolo,
  • Angelo Michele Inchingolo,
  • Tea Romasco,
  • Margherita Tumedei,
  • Alessandro Specchiulli,
  • Adriano Piattelli and
  • Bartolomeo Trentadue

16 November 2023

The issue of dental implant placement relative to the alveolar crest, whether in supracrestal, equicrestal, or subcrestal positions, remains highly controversial, leading to conflicting data in various studies. Three-dimensional (3D) Finite Element A...

  • Review
  • Open Access

Versatility of the Cone Beam Computed Tomography in Oral Surgery: An Overview

  • Kishan G. Panicker,
  • Anuroopa Pudukulangara Nair and
  • Bipin Chandra Reddy

Cone beam CT (CBCT) produces threedimensional information on the facial skeleton, teeth and their surrounding tissues; and is increasingly being used in many of the dental specialties. This is usually achieved with a substantially lower effective dos...

  • Case Report
  • Open Access
1 Citations
1,335 Views
15 Pages

The Prosthetic Rehabilitation of Maxillary Aesthetic Area Guided by a Multidisciplinary Approach: A Case Report with Histomorphometric Evaluation

  • Stefano Speroni,
  • Luca Antonelli,
  • Luca Coccoluto,
  • Marco Giuffrè,
  • Alessandro Zucchelli,
  • Francesco Sarnelli,
  • Vincenzo Ronsivalle and
  • Giovanni Zucchelli

Background: The rehabilitation of complex bone defects in the anterior maxilla presents significant challenges in restoring both function and esthetics. A multidisciplinary approach integrating guided bone regeneration (GBR) and connective tissue gra...

  • Article
  • Open Access
7 Citations
3,574 Views
12 Pages

Morphometric Analysis of the Mandibular Canal and Its Anatomical Variants in a Chilean Subpopulation: Cone Beam Computed Tomography Study

  • Jacob Guzmán,
  • Jaime Abarca,
  • Pablo Navarro,
  • Ivonne Garay,
  • Josep Arnabat-Domínguez and
  • Pablo Betancourt

30 August 2024

The inferior alveolar nerve (IAN), contained within the mandibular canal (MC), is a structure prone to damage in clinical and surgical procedures on the mandible. This study aimed to analyze the MC morphology and its anatomical variants in a Chilean...

  • Article
  • Open Access
576 Views
10 Pages

CBCT Evaluation of Cortical Bone Thickness in the Nasal Floor and Lateral Wall: Considerations for Implant Anchorage—A Retrospective Multicentre Study

  • Fodor Romulus Calin,
  • Bartosz Dalewski,
  • Stefan Ihde,
  • Marta Czuczwał,
  • Vitomir S. Konstantinovic,
  • Vivek Gaur,
  • Jacek Kotuła and
  • Łukasz Pałka

14 November 2025

Background/Objectives: Primary implant stability depends on cortical bone thickness. While alveolar cortices are well studied, little is known about the nasal floor and lateral wall, which may provide alternative anchorage in atrophic maxillae. Metho...

  • Article
  • Open Access
3 Citations
4,757 Views
11 Pages

A Randomized Controlled Trial Comparing Collagen Matrix to Hemostatic Gelatin Sponge as Socket Seal in Alveolar Ridge Preservation

  • Célien Eeckhout,
  • Lorenz Seyssens,
  • Maarten Glibert,
  • Laurens Keppens,
  • Baptist Nollet,
  • Martijn Lambert and
  • Jan Cosyn

16 April 2024

(1) Objectives: This study aimed to compare a collagen matrix to a hemostatic gelatin sponge as a socket seal in alveolar ridge preservation (ARP). (2) Methods: Systemically healthy patients planned for ARP at two sites with more than 50% of the bucc...

  • Article
  • Open Access
226 Views
21 Pages

Early Osseous Proliferation in Spiraled Healing Chambers Resulted After the Insertion of Titanium Implants in Cortical Bone of a Rabbit

  • Cristian Adrian Ratiu,
  • Danut Dejeu,
  • Camelia Anca Croitoru,
  • Adrian Todor,
  • Ioana Adela Ratiu,
  • Ruxandra Elena Luca,
  • Corina Moisa,
  • Viorel Miclaus and
  • Vasile Rus

29 December 2025

Background and Objectives: The insertion of endosseous implants requires the alveolar bone to be drilled, which produces alterations of the osseous neoalveolus approximately 1 mm deep, an area that will later be subjected to osseous renewal. The heal...

  • Article
  • Open Access
7 Citations
5,721 Views
13 Pages

Tissue Expansion Improves the Outcome and Predictability for Alveolar Bone Augmentation: Prospective, Multicenter, Randomized Controlled Trial

  • Soo-Hwan Byun,
  • Sun-Hyun Kim,
  • Sura Cho,
  • Ho Lee,
  • Ho-Kyung Lim,
  • Ju-Won Kim,
  • Ui-Lyong Lee,
  • Wan Song,
  • Sun-Jong Kim and
  • Jin-Woo Kim

16 April 2020

Objectives: The purpose of this study was to evaluate the effectiveness of the intraoral use of subperiosteally placed self-inflating tissue expanders for subsequent bone augmentation and implant integrity. Material and methods: A prospective, multic...

  • Case Report
  • Open Access
4 Citations
2,442 Views
8 Pages

13 March 2025

Background/Objectives: Miniscrew-assisted rapid palatal expansion (MARPE) has been increasingly used as a nonsurgical alternative for maxillary expansion in adults. However, reports of complications remain limited. This case describes a rare instance...

  • Systematic Review
  • Open Access
2 Citations
7,142 Views
12 Pages

The Influence of Root Prominence on the Onset of Gingival Recession: A Systematic Review

  • Girolamo Raso,
  • Nuno Bernardo Malta dos Santos,
  • Leonardo M. Nassani,
  • Anna Carolina Volpi Mello-Moura,
  • Juliana Campos Hasse Fernandes and
  • Gustavo Vicentis Oliveira Fernandes

12 March 2024

This systematic review aimed to identify, evaluate, and summarize the results of relevant studies on radicular prominence and its relationship with gingival recessions. This review was conducted according to the PRISMA (Preferred Reporting Reviews an...

  • Article
  • Open Access
9 Citations
2,812 Views
11 Pages

22 October 2023

This retrospective study aims to investigate the impact of cone-beam computed tomography (CBCT) viewing parameters such as contrast, slice thickness, and sharpness on the identification of the inferior alveolar nerve (IAC). A total of 25 CBCT scans,...

  • Article
  • Open Access
1 Citations
3,063 Views
19 Pages

Chamomile Tincture and Lidocaine Hydrochloride Gel Ameliorates Periodontitis: A Preclinical Study

  • Jiahui Sun,
  • Huiyi Wang,
  • Junhong Xiao,
  • Qiudong Yang,
  • Heyu Liu,
  • Zhengkun Yang,
  • Yuqi Liu,
  • Xin Huang,
  • Liu Yang and
  • Zhengguo Cao

17 November 2024

Background/Objectives: Periodontitis is a common oral disease marked by gingival inflammation and alveolar bone loss. This study evaluated the efficacy of chamomile tincture and lidocaine hydrochloride (CLH) gel in mitigating periodontal inflammation...

  • Article
  • Open Access
5 Citations
2,855 Views
13 Pages

The Cone Beam Computed Tomography Evaluation of Cortical Bone Plate after Piezocision-Assisted Orthodontic Upper Arch Expansion: A Case Series

  • Maria Julia Pietruska,
  • Emilia Waszkiewicz,
  • Anna Skurska,
  • Eugeniusz Sajewicz,
  • Ewa Dolińska and
  • Małgorzata Pietruska

18 November 2021

Background: The purpose of the study was to evaluate cone beam computed tomography (CBCT) after piezocision-assisted orthodontic maxillary arch expansion. Methods: Forty CBCT images of 20 patients taken before and after treatment were included in the...

  • Article
  • Open Access
1 Citations
2,145 Views
23 Pages

A New Preclinical Surgical Model for the Assessment of Dental Implant Tissue Integration

  • Ryan Noh,
  • Nahrain Warda,
  • Charles Tremblay and
  • John E. Davies

Background/Objectives: The structural integrity and strength of the transgingival soft tissue seal around dental implant surfaces remain critical challenges. Therefore, animal models should include all three implant/tissue interfaces: bone, connectiv...

  • Article
  • Open Access
17 Citations
8,420 Views
14 Pages

24 January 2023

Proper horizontal and vertical thickness of the gingival connective tissue has been proven to be one of the success criteria in dental implant and reconstructive surgery. When thin tissue is found, gingiva augmentation methods can be used to increase...

  • Systematic Review
  • Open Access
12 Citations
3,790 Views
17 Pages

Post-Treatment Status of Impacted Maxillary Central Incisors following Surgical-Orthodontic Treatment: A Systematic Review

  • Alvyda Žarovienė,
  • Dominyka Grinkevičienė,
  • Giedrė Trakinienė and
  • Dalia Smailienė

30 July 2021

Background and Objectives: The aim of this systematic review was to summarize currently available data of published articles that have investigated the post-treatment status of impacted maxillary central incisors (ICI) treated by the surgical-orthodo...

  • Article
  • Open Access
10 Citations
4,785 Views
14 Pages

12 July 2022

Background: In this study, we evaluated the effect of periodontal splints made from different materials on the stress distributions in compromised periodontal tissues and cement layers, using a computer simulation of mastication. Methods: Twenty-five...

  • Article
  • Open Access
2 Citations
2,012 Views
17 Pages

Bone Remodeling Around Implants with Different Macro-Design Placed in Post-Extraction Sockets: A Cone-Beam Computed Tomography (CBCT) Randomized Controlled Clinical Trial (RCT)

  • Roberta Grassi,
  • Fábio França Vieira e Silva,
  • Gennaro Musella,
  • Francesco Pettini,
  • Gisela Cristina Vianna Camolesi,
  • Martina Coppini and
  • Stefania Cantore

11 February 2025

Background: Immediate post-extraction dental implants are increasingly popular, but ensuring primary stability and managing peri-implant tissues remain challenging. Implant macro-design significantly impacts stability and osseointegration. This study...

  • Article
  • Open Access
188 Views
15 Pages

The Evolution of Extended Platelet-Rich Fibrin Membranes for Socket Grafting: Part Two: A Randomized Clinical Trial Comparing These Membranes with Collagen Membranes

  • Nathan E. Estrin,
  • Paras Ahmad,
  • Troy B. Tran,
  • Alan Rene Espinoza,
  • Ryan Holmes,
  • Jean-Claude Imber,
  • Nima Farshidfar and
  • Richard J. Miron

12 January 2026

Background: Extended platelet-rich fibrin (e-PRF) membranes are a novel 100% autologous biomaterial with a longer resorption time (4–6 months) than traditional solid-PRF membranes (two weeks). In part 1 of this 2-part publication series, four c...

  • Article
  • Open Access
5,588 Views
32 Pages

Unraveling the Life History of Past Populations through Hypercementosis: Insights into Cementum Apposition Patterns and Possible Etiologies Using Micro-CT and Confocal Microscopy

  • Léa Massé,
  • Emmanuel d’Incau,
  • Antoine Souron,
  • Nicolas Vanderesse,
  • Frédéric Santos,
  • Bruno Maureille and
  • Adeline Le Cabec

13 January 2024

The “teeth-as-tools” hypothesis posits that Neanderthals used their anterior teeth as a tool or a third hand for non-dietary purposes. These non- or para-masticatory activities (e.g., tool-making or food preparation prior to ingestion) ha...

  • Article
  • Open Access
56 Views
20 Pages

Tension-Dominant Orthodontic Loading and Buccal Periodontal Phenotype Preservation: An Integrative Mechanobiological Model Supported by FEM and a Proof-of-Concept CBCT

  • Anna Ewa Kuc,
  • Jacek Kotuła,
  • Kamil Sybilski,
  • Szymon Saternus,
  • Jerzy Małachowski,
  • Natalia Kuc,
  • Grzegorz Hajduk,
  • Joanna Lis,
  • Beata Kawala and
  • Magdalena Sulewska

Background: Adult patients with a thin buccal cortical plate and fragile periodontal phenotype are at high risk of dehiscence, fenestration and recession during transverse orthodontic expansion. Conventional mechanics often create a cervical compress...

  • Article
  • Open Access
3 Citations
2,373 Views
13 Pages

Human Dental Pulp Stem Cells Differentiate into Cementoid-Like-Secreting Cells on Decellularized Teeth Scaffolds

  • Manuel Mata,
  • Santiago Peydró,
  • José Javier Martín de Llano,
  • María Sancho-Tello and
  • Carmen Carda

9 December 2022

Periodontitis is a common inflammatory disease that in some cases can cause tooth loss. Cementum is a mineralized tissue that forms part of the insertion periodontium and serves to fix the teeth to the alveolar bone. In addition, it acts as a reservo...

  • Case Report
  • Open Access
622 Views
23 Pages

28 October 2025

Background: Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity, often necessitating extensive surgical resection. Such interventions may result in complex intraoral defects requiring immediate reconstruction to resto...

  • Case Report
  • Open Access
630 Views
17 Pages

“Diving into the Gray Zone”: A Case Report of a 19-Year-Old Patient Treated with Tooth-Borne Rapid Maxillary Expansion

  • Valentina Coviello,
  • Davide Gentile,
  • Edoardo Staderini,
  • Andrea Camodeca,
  • Angela Guarino and
  • Massimo Cordaro

10 November 2025

Background: This case report aimed to quantify dental, alveolar, and skeletal changes, periodontal health, and sleep quality after treatment with a tooth-borne rapid palatal expander (RPE) in a young adult with bilateral posterior crossbite due to tr...

  • Article
  • Open Access
15 Citations
6,307 Views
10 Pages

16 August 2017

Hydroxyapatite (HA) coatings on titanium have been investigated for many years, and have demonstrated advantageous biocompatibility in dental implants. Animal experiments have demonstrated that the biological response to plasma-sprayed HA-coated impl...

  • Article
  • Open Access
7 Citations
2,628 Views
19 Pages

Mandibular Overdenture Supported by Two or Four Unsplinted or Two Splinted Ti-Zr Mini-Implants: In Vitro Study of Peri-Implant and Edentulous Area Strains

  • Dario Puljic,
  • Nikola Petricevic,
  • Asja Celebic,
  • Ines Kovacic,
  • Manuela Milos,
  • Dalibor Pavic and
  • Ognjen Milat

Clinical indications for the newly released Ti-Zr (Roxolid®) alloy mini-implants (MDIs) aimed for overdenture (OD) retention in subjects with narrow alveolar ridges are not fully defined. The aim of this study was to analyze peri-implant and post...

  • Feature Paper
  • Article
  • Open Access
75 Citations
6,862 Views
17 Pages

PLA-Based Mineral-Doped Scaffolds Seeded with Human Periapical Cyst-Derived MSCs: A Promising Tool for Regenerative Healing in Dentistry

  • Marco Tatullo,
  • Gianrico Spagnuolo,
  • Bruna Codispoti,
  • Fausto Zamparini,
  • Anqi Zhang,
  • Micaela Degli Esposti,
  • Conrado Aparicio,
  • Carlo Rengo,
  • Manuel Nuzzolese and
  • Maria Giovanna Gandolfi
  • + 3 authors

16 February 2019

Human periapical cyst mesenchymal stem cells (hPCy-MSCs) are a newly discovered cell population innovatively collected from inflammatory periapical cysts. The use of this biological waste guarantees a source of stem cells without any impact on the su...

  • Article
  • Open Access
2 Citations
2,319 Views
20 Pages

11 March 2025

(1) Background and Objectives: Congenitally missing bilateral maxillary lateral incisors (CMBMLIs) present significant aesthetic, functional, and psychosocial challenges that require an orthodontic approach based on multidisciplinary consensus. The a...

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