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Pathogens publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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HIV Reservoir Dynamics and Latency Mechanisms Under Current and Emerging Antiviral Strategies

edited by

Chen Zhang

and

Prasanta K. Dash

submission deadline 31 Aug 2026 | Viewed by 595 | Submission Open

Keywords: HIV reservoirs; HIV latency mechanisms; reservoir persistence; reservoir dynamics prediction; HIV therapies; reservoir targeting; reservoir eradication strategies; new gene-editing delivery vehicles

(This special issue belongs to the Section Viral Pathogens)

Regulation of Host Innate Immunity During Pathogens Infection

edited by

Xin Ran

submission deadline 31 Aug 2026 | Viewed by 250 | Submission Open

Keywords: pathogens; bacterial pathogens; pattern-recognition receptors; innate immune circuits; gram-negative and gram-positive infections; inflammasome activation

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Transmission and Control of Antimicrobial-Resistant Pathogens in Animal-Derived Foods: Molecular Mechanisms from Farm to Fork

edited by

Martina Rega

and

Mauro Conter

submission deadline 31 Aug 2026 | Viewed by 183 | Submission Open

Keywords: antimicrobial resistance; food safety; molecular mechanisms; One Health; veterinary public health

Innovative Strategies Against Resistant Bacterial Infections: Bacteriophage Therapy

edited by

Katarzyna Kosznik-Kwaśnicka

Agnieszka Necel

and

Byeonghwa Jeon

submission deadline 1 Sep 2026 | 1 articles | Viewed by 672 | Submission Open

Keywords: bacteriophage therapy; antimicrobial resistance; multidrug-resistant bacteria; phage–antibiotic synergy; phage-derived enzymes; biofilms; alternative antimicrobials; phage genomics

(This special issue belongs to the Section Bacterial Pathogens)

Immunopathogenesis of Influenza and Respiratory Syncytial Virus Infection

edited by

Norbert J. Roberts, Jr.

submission deadline 10 Sep 2026 | 2 articles | Viewed by 5792 | Submission Open

Keywords: influenza virus; respiratory syncytial virus; viral pathogenesis; monocytes–macrophages; lymphocytes

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Epidemiology, Diagnostics, and Therapeutics of High-Risk Human Papillomavirus (HPV) Infections

edited by Zhengchun Lu and Guang Fan

submission deadline 10 Sep 2026 | 3 articles | Viewed by 2327 | Submission Open

Keywords: high-risk HPV; HPV-associated diseases; screening and diagnostics; HPV epidemiology; therapeutic and preventive strategies

(This special issue belongs to the Section Viral Pathogens)

Virulence and Resistance Mechanisms in Multidrug-Resistant Gram-Negative Bacteria: 2nd Edition

edited by

Steven E. Fiester

and

William Penwell

submission deadline 10 Sep 2026 | 1 articles | Viewed by 1013 | Submission Open

Keywords: antibiotic resistance mechanisms; MDR gram-negative bacteria; gram-negative nosocomial infections; carbapenem-resistant Enterobacteriaceae infections; bacterial infection

(This special issue belongs to the Section Bacterial Pathogens)

Viral Infection and Antiviral Drug

edited by Hiya Lahiri and

Jochen Bodem

submission deadline 10 Sep 2026 | Viewed by 283 | Submission Open

Keywords: viral diseases; structural analysis; antivirals; artificial intelligence

(This special issue belongs to the Section Viral Pathogens)

Surveillance, Prevention and Control of Sexually Transmitted Infections

edited by

Miguel A. Sánchez-Alemán

submission deadline 15 Sep 2026 | 2 articles | Viewed by 2711 | Submission Open

Keywords: sexually transmitted infections; syphilis; herpes, papillomavirus; HIV; sexual health; epidemiology; reproductive health; prevention; diagnosis; treatment

Polyamines, Arginine and Pathogens: From Fundamental Biology to Host-Pathogen Dynamics

edited by

Sigrid C. Roberts

and

Nicola Carter

submission deadline 15 Sep 2026 | 3 articles | Viewed by 2197 | Submission Open

Keywords: pathogens; polyamines; polyamine metabolism; putrescine; spermidine; spermine; arginase; eiF5A; host–pathogen interactions; infectious diseases; bacteria; viruses; parasites

Discovery of Novel Antiprotozoal Agents: Current Status and Future Perspectives

edited by

Klinger Antonio da Franca Rodrigues

submission deadline 15 Sep 2026 | 2 articles | Viewed by 2041 | Submission Open

Keywords: neglected tropical diseases; drug discovery; natural products; medicinal chemistry

(This special issue belongs to the Section Parasitic Pathogens)

Molecular Mechanisms and Clinical Management of HIV–Hepatitis Virus Coinfections

edited by

Ana Maria Tudor

and

Anna Rosa Garbuglia

submission deadline 15 Sep 2026 | Viewed by 242 | Submission Open

Keywords: HIV-hepatitis coinfection; liver disease progression; antiviral therapy; clinical management

(This special issue belongs to the Section Viral Pathogens)

Pathogen–Host Interactions: Death, Defense, and Disease

edited by Hongyan Guo and Heather S. Koehler

submission deadline 20 Sep 2026 | 9 articles | Viewed by 21382 | Submission Open

Keywords: host–pathogen interaction; immune evasion; virulence factors; antimicrobial resistance; zoonosis

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Emerging and Re-Emerging Avian Influenza Viruses in Wildlife

edited by

Klaudia Chrzastek

submission deadline 20 Sep 2026 | 3 articles | Viewed by 11298 | Submission Open

Keywords: avian influenza virus; HPAIV; LPAIV; wildlife; surveillance; epidemiology; phylogenetics; next-generation sequencing

(This special issue belongs to the Section Viral Pathogens)

Epidemiology and Molecular Detection of Emerging Fungal Pathogens

edited by

Claudio Farina

submission deadline 20 Sep 2026 | 6 articles | Viewed by 8352 | Submission Open

Keywords: epidemiology; molecular detection; emerging fungi; uncommon presentation

(This special issue belongs to the Section Fungal Pathogens)

Parasitic Infections in Animals

edited by

Thais Rabelo Dos Santos-Doni

submission deadline 20 Sep 2026 | 2 articles | Viewed by 2321 | Submission Open

Keywords: veterinary parasitology; zoonotic parasites; vector-borne diseases; epidemiology; one health

(This special issue belongs to the Section Parasitic Pathogens)

Proteomic Approaches in Different Animal Pathogens

edited by

Leandro Abreu Da Fonseca

Leandro Licursi de Oliveira

and Mariana Machado Neves

submission deadline 20 Sep 2026 | 1 articles | Viewed by 1444 | Submission Open

Keywords: animal pathogens; proteomics; host–pathogen interaction; mass spectrometry; biomarkers; veterinary diagnostics; pathogen virulence factors; one health; multiomics; antimicrobial resistance

Reviews of Infectious Diseases—2nd Edition

edited by

Giancarlo Ceccarelli

submission deadline 20 Sep 2026 | 1 articles | Viewed by 786 | Submission Open

Keywords: infectious diseases; virus; bacteria; parasitic diseases

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

HIV-TB Co-Infection and Pediatric Pathogen Dynamics

edited by Boris Kevin Tchounga

submission deadline 20 Sep 2026 | Viewed by 382 | Submission Open

Keywords: TB/HIV coinfection; TB preventive therapy; children adolescent living with HIV; epidemiology; diagnosis; clinical management; advanced HIV disease

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Hepatitis Research: Current Trends

edited by

Wenyu Lin

submission deadline 21 Sep 2026 | Viewed by 319 | Submission Open

Keywords: hepatitis; liver disease; viral infection; antiviral therapy; vaccine development; immunopathogenesis; public health

Leishmania & Leishmaniasis

edited by

Maria Inês Fernandes Pimentel

and

Liliane de Fátima Antonio Oliveira

submission deadline 25 Sep 2026 | 5 articles | Viewed by 11319 | Submission Open

Keywords: leishmaniasis; visceral leishmaniasis; cutaneous leishmaniasis; mucosal leishmaniasis; mucocutaneous leishmaniasis; human visceral leishmaniasis; canine visceral leishmaniasis

(This special issue belongs to the Section Parasitic Pathogens)

Antibiotic Resistance and Survival Strategies in Pathogens

edited by

Karolina Stojowska-Swędrzyńska

and Dorota Kuczyńska-Wiśnik

submission deadline 25 Sep 2026 | 3 articles | Viewed by 4556 | Submission Open

Keywords: antibiotic resistance; antibiotic tolerance; persister cells; VBNC state; multidrug resistance; resistant pathogens; mechanisms of antimicrobial resistance; antibiotic-resistant genes; alternative antimicrobial strategies; chronic infections

(This special issue belongs to the Section Bacterial Pathogens)

Emerging Zoonoses and Sustainable One Health Strategies

edited by

Narcisa Mederle

submission deadline 25 Sep 2026 | Viewed by 334 | Submission Open

Keywords: emerging zoonoses; one health; diagnosis; control; sustainable strategies; animal welfare; public health

(This special issue belongs to the Section Emerging Pathogens)

New Insights into Ticks and Tick-Borne Pathogens: From Understanding to Control

edited by

Agustin Estrada Pena

and

Alejandro Cabezas-Cruz

submission deadline 25 Sep 2026 | Viewed by 319 | Submission Open

Keywords: ticks; tick-borne pathogens; tick-borne diseases; transmit; molecular detection methods

(This special issue belongs to the Section Ticks)

Synergistic Strategies of Engineered Microbes and Biomaterials for Infection and Cancer Therapy

edited by

Jun Liu

and Ruijuan Li

submission deadline 25 Sep 2026 | Viewed by 211 | Submission Open

Keywords: microbes; biomaterials; infection; cancer therapy

Nosocomial Infections and Antimicrobial Resistance: Challenges and Solutions

edited by

Juan Manuel Bello-López

and

Miguel Ángel Loyola-Cruz

submission deadline 30 Sep 2026 | 4 articles | Viewed by 9445 | Submission Open

Keywords: nosocomial infections; antimicrobial resistance; molecular epidemiology; genomic surveillance; ESKAPE bacteria

(This special issue belongs to the Section Bacterial Pathogens)

Epidemiology of Vector-Borne Pathogens

edited by

Iva Christova

submission deadline 30 Sep 2026 | 8 articles | Viewed by 8912 | Submission Open

Keywords: vector-borne infectious diseases; epidemiology; transmission dynamics; disease surveillance

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Pediatric Viral Infections: Epidemiology, Treatment, and Emerging Challenges

edited by

Maria Pokorska-Śpiewak

and Magdalena Rutkowska

submission deadline 30 Sep 2026 | 7 articles | Viewed by 8612 | Submission Open

Keywords: pediatric infectious diseases; viral infections; viral hepatitis; COVID-19; HIV; mother-to-child transmission; vaccines

(This special issue belongs to the Section Viral Pathogens)

Drug Resistant Pathogens: Diagnosis, Treatment, and Global Health Implications

edited by

Giuseppe Pipitone

Alberto Enrico Maraolo

and

Luigi Principe

submission deadline 30 Sep 2026 | 4 articles | Viewed by 8117 | Submission Open

Keywords: antibiotics; multi-drug-resistant microorganisms; difficult-to-treat infections

(This special issue belongs to the Section Bacterial Pathogens)

Dairy Cattle Health: Mastitis, Milk Quality, and Antimicrobial Resistance from a One Health Perspective

edited by

Alfonso Zecconi

submission deadline 30 Sep 2026 | 4 articles | Viewed by 6571 | Submission Open

Keywords: udder immune defenses; inflammation; milk leukocytes; mastitis control; One Health approach; immune components in milk

(This special issue belongs to the Section Bacterial Pathogens)

Molecular Aspects of Host-Parasite Interactions

edited by

Fabrizio Bruschi

submission deadline 30 Sep 2026 | 5 articles | Viewed by 6137 | Submission Open

Keywords: immune response molecules; escape mechanisms; immunomodulation; vaccines; diagnostic tools

(This special issue belongs to the Section Parasitic Pathogens)

Emerging Viral Pathogens: Diagnosis, Treatment, and Public Health Interventions

edited by

Jasper Fuk-Woo Chan

and Vivian Huiping Shuai

submission deadline 30 Sep 2026 | 4 articles | Viewed by 6050 | Submission Open

Keywords: virus discovery; pathogenesis; antivirals; diagnostics; vaccines; public health

(This special issue belongs to the Section Emerging Pathogens)

Advancing Vaccine Strategies and Technologies for Controlling Swine Infectious Diseases

edited by

Jishu Shi

and

Lihua Wang

submission deadline 30 Sep 2026 | 3 articles | Viewed by 5002 | Submission Open

Keywords: autogenous vaccines; swine infectious diseases; adjuvants; diagnostics; swine veterinarian

(This special issue belongs to the Section Vaccines and Therapeutic Developments)

Malaria: Updates on Prevention, Diagnosis, and Treatment

edited by Temi Lampejo and

Andrew Taylor-Robinson

submission deadline 30 Sep 2026 | 3 articles | Viewed by 4856 | Submission Open

Keywords: malaria; plasmodium; prevention; vaccines; therapeutics

(This special issue belongs to the Section Parasitic Pathogens)

New Insights into Antibiotic-Resistant Pathogens Within the One Health Framework: Epidemiology, Mechanisms and Strategies for Eradication

edited by

Uriel Alberto Angulo-Zamudio

, Vicente Adrián Canizalez-Román and

Nidia M. León-Sicairos

submission deadline 30 Sep 2026 | 4 articles | Viewed by 4813 | Submission Open

Keywords: antibiotic resistance; pathogens; pandemic; epidemiology; one health

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

HIV/AIDS Co-Infections and Non-AIDS Co-Morbidities

edited by

Manuela C. Arbune

and Florentina Dumitrescu

submission deadline 30 Sep 2026 | 3 articles | Viewed by 4658 | Submission Open

Keywords: HIV; AIDS; non-AIDS co-infections; non-AIDS comorbidities; non-AIDS cancers; chronic inflammation; HIV-associated aging; morbidity and mortality; antiretroviral therapies (ARTs); non-communicable diseases (NCDs)

One Health: New Approaches, Research, and Innovation to Zoonoses—2nd Edition

edited by

Chrysa Voyiatzaki

submission deadline 30 Sep 2026 | 1 articles | Viewed by 4134 | Submission Open

Keywords: zoonoses; human–animal–environment interaction; bacteria; fungi; parasites; prion; virus

Biomarkers in Infectious Diseases

edited by

Yiu Wing (Jason) Kam

submission deadline 30 Sep 2026 | 3 articles | Viewed by 3822 | Submission Open

Keywords: infectious diseases; immune response; diagnostic biomarker; prognostic biomarker; pathogen-specific biomarker; biomarker validation; biomarker-guided therapy

Aquatic Pathogens and Host Immune Responses

edited by

Patricia Pereiro

submission deadline 30 Sep 2026 | 3 articles | Viewed by 3779 | Submission Open

Keywords: aquaculture; diseases; immunity; vaccines; treatments

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

From Gastroenteritis to Emerging Threats: One Health Surveillance of Viral Infections

edited by

Adriana Luchs

and

Natalia Coelho Couto de Azevedo Fernandes

submission deadline 30 Sep 2026 | 2 articles | Viewed by 3349 | Submission Open

Keywords: viral gastroenteritis; pathology of viral infections; fecal-borne diseases; one Health; interspecies transmission; molecular epidemiology; zoonotic viruses; environmental surveillance; foodborne and waterborne pathogen

(This special issue belongs to the Section Viral Pathogens)

Innate Immune Response and Pathogen Dynamics

edited by Guido Sireci

submission deadline 30 Sep 2026 | 3 articles | Viewed by 3321 | Submission Open

Keywords: complement; natural killer; phagocytosis; DNA extracellular traps release

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Viral Infections, Chronic Inflammation and Carcinogenesis

edited by

Angioletta Lasagna

and Davide Dalu

submission deadline 30 Sep 2026 | 3 articles | Viewed by 2574 | Submission Open

Keywords: oncogenic virus; HPV; AIDS-related cancers; HCV; HBV; hit-and-run theory; vaccination

(This special issue belongs to the Section Viral Pathogens)

Epidemiology, Diagnosis and Clinical Management of Human Parasitic Infections—2nd Edition

edited by

Marcia Aparecida Speranca

and

Aline Diniz Cabral

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2210 | Submission Open

Keywords: parasitic infectious diseases; eco-epidemiology; diagnosis; treatment; clinical management; prevention

(This special issue belongs to the Section Parasitic Pathogens)

Vector-Borne Diseases and Transboundary Zoonoses: A One Health Perspective

edited by

Rafael Felipe da Costa Vieira

and

Richard de Campos Pacheco

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1458 | Submission Open

Keywords: zoonoses; one health approach; vector control; pathogen transmission; animal reservoirs; emerging infectious diseases; veterinary medicine; disease surveillance; epidemiology

Microbial Interactions in Ticks: Pathogen–Pathogen and Pathogen–Non-Pathogenic Microorganism Dynamics in Coinfections

edited by

Elianne Piloto-Sardiñas

, Islay Rodríguez and

Huarrisson Azevedo Santos

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1022 | Submission Open

Keywords: tick-borne pathogens; microbial interactions; tick-borne coinfection; microbiome; vector competence

(This special issue belongs to the Section Ticks)

Plant–Virus Interactions: From Molecular Mechanisms to Crop Protection

edited by

Hernan Garcia-Ruiz

submission deadline 30 Sep 2026 | 1 articles | Viewed by 798 | Submission Open

Keywords: plant–virus interactions; molecular mechanisms; antiviral strategies; CRISPR/Cas; RNA interference; viral diagnostics; crop resistance; pathogenesis; sustainable crop protection; biotechnological control

(This special issue belongs to the Section Viral Pathogens)

Emerging Topics in Bat-Borne Pathogens

edited by