Innovative Strategies Against Resistant Bacterial Infections: Bacteriophage Therapy
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Bacterial Pathogens".
Deadline for manuscript submissions: 1 September 2026 | Viewed by 796
Editors
Interests: phage therapy; bacteriophage; antibiotic resistance; phage-antimicrobial synergy
Interests: bacteriophage; antibiotic resistance; phage development
Interests: foodborne pathogens; stress tolerance; antibiotic resistance; phage therapy
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Special Issue Information
Dear Colleagues,
The rapid global spread of antibiotic-resistant bacteria represents one of the most critical threats to public health in the 21st century. The diminishing efficacy of conventional antibiotics has created an urgent need for innovative and alternative therapeutic strategies to prevent and treat bacterial infections. Among these, bacteriophage therapy has re-emerged as a promising, targeted, and biologically precise approach to combat multidrug-resistant pathogens.
This Special Issue aims to provide a multidisciplinary platform for cutting-edge research and comprehensive reviews focusing on bacteriophage therapy and related phage-based approaches like the use of phage-derived enzymes of phage-antibiotic combinations.
Topics of interest include, but are not limited to, the following:
- Isolation, characterization, and genomics of therapeutic bacteriophages;
- Phage–host interactions and bacterial resistance mechanisms;
- Phage-derived enzymes (endolysins, depolymerases);
- Phage therapy in clinical, veterinary, and environmental settings;
- Phage–antibiotic synergy and combination therapies;
- Biofilm control using bacteriophages;
- Engineering and synthetic biology approaches in phage therapy;
- Delivery systems, formulation, and pharmacokinetics of phages;
- Regulatory, ethical, and safety aspects of phage therapy;
- Case studies and clinical trials involving phage-based treatments.
I look forward to your valuable contributions and to advancing this rapidly evolving field together.
Dr. Katarzyna Kosznik-Kwaśnicka
Dr. Agnieszka Necel
Dr. Byeonghwa Jeon
Guest Editors
Manuscript Submission Information
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Keywords
- bacteriophage therapy
- antimicrobial resistance
- multidrug-resistant bacteria
- phage–antibiotic synergy
- phage-derived enzymes
- biofilms
- alternative antimicrobials
- phage genomics
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