HIV-TB Co-Infection and Pediatric Pathogen Dynamics
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Epidemiology of Infectious Diseases".
Deadline for manuscript submissions: 15 March 2026 | Viewed by 8
Special Issue Editor
Interests: paediatric HIV; TB; coinfection
Special Issue Information
Dear Colleagues,
HIV and TB coinfection remains a major clinical, biological, and implementation challenge for HIV programs, as it significantly increases the risk of severe illness and death, especially in high HIV prevalence and TB burden regions. Children living with HIV are more susceptible to TB infection and more likely to progress to TB disease. At the same time, late diagnosis and/or suboptimal treatment of TB disease accelerates HIV disease progression, leading to death. Timely and effective uptake of appropriate TB preventive therapy options is a necessary step to avoid TB/HIV coinfection in children living with HIV. Early diagnosis using the most accurate biological method, along with dose-sensitive TB treatment and age/weight-appropriate antiretroviral therapies, are crucial for improving outcomes.
Despite all the progress, such as a reduction in TB deaths among people living with HIV and availability of molecular technics for TB and HIV early diagnosis, an important gap remains in the number of pediatric TB reported, and the persistent early mortality among children initiating ART suggest gaps in TB/HIV prevention and management.
This Special Issue is devoted to collecting original papers and/or review papers about epidemiology, pathogen dynamics, prevention, diagnosis, management and long-term post-TB treatment outcomes among children coinfected with HIV and TB.
Dr. Boris Kevin Tchounga
Guest Editor
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Keywords
- TB/HIV coinfection
- TB preventive therapy
- children adolescent living with HIV
- epidemiology
- diagnosis
- clinical management
- advanced HIV disease
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