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Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Lipid Metabolism Pathways: From Life to Disease

edited by

Anna Eiring

submission deadline 19 Jun 2026 | 1 articles | Viewed by 5586 | Submission Open

Keywords: lipid metabolism; lipid signaling; apoptosis; ferroptosis; autophagy; membrane dynamics; fatty acid oxidation; obesity

(This special issue belongs to the Section Cell Biology and Tissue Engineering)

Dive into Myopia

edited by

Chun-Fu Liu

submission deadline 19 Jun 2026 | 3 articles | Viewed by 3519 | Submission Open

Keywords: myopia; hyperopia; myopia control; axial length; axial length retardation; axial length elongation; myopia complications; refraction measurement; atropine; rebound effect; orthokeratology; missight; defocus incorporated multiple segments (DIMSs); highly aspherical lenslets (HALs); red light; repeated low-level red light (RLRL) therapy; enhance myopia control; customized myopia control; peripheral refraction; peripheral myopia; refractive surgery; PRK; LASIK; smile; contact lens; spectacles

(This special issue belongs to the Section Medical Research)

Advances in Knee Biomechanics—2nd Edition

edited by Jason Shearn

submission deadline 22 Jun 2026 | Viewed by 72 | Submission Open

Keywords: knee; tendon; ligament; injury; repair; healing; biomechanics; advanced techniques

(This special issue belongs to the Section Physiology and Pathology)

Reconstruction of Bone Defects

edited by

Jörg Eschweiler

and

Philipp Kobbe

submission deadline 23 Jun 2026 | 6 articles | Viewed by 8781 | Submission Open

Keywords: bone and fracture biomechanics; bone healing; critical size bone defects; fracture non-union; inflammation; joint arthroplasty and fracture osteosynthesis; implant designs; materials proprieties; patient selection; primary and revision settings

(This special issue belongs to the Section Medical Research)

Recent Advances in Vascular Biology and Chronic Kidney Disease (CKD)

edited by

Yongseek Park

submission deadline 26 Jun 2026 | 1 articles | Viewed by 6703 | Submission Open

Keywords: chronic kidney disease; vascular dysfunction; endothelial cells

(This special issue belongs to the Section Medical Research)

Advances in Anesthesia and Critical Care

edited by

Gabriele Melegari

submission deadline 26 Jun 2026 | 5 articles | Viewed by 6091 | Submission Open

Keywords: anesthesia; intensive care training; updates in anesthesia; machine learning

(This special issue belongs to the Section Medical Research)

Advances in Dryland Agriculture Science

edited by

Liangshan Feng

and Hangyu Dong

submission deadline 26 Jun 2026 | 3 articles | Viewed by 3868 | Submission Open

Keywords: dry farming; climate smart agriculture; soil and water protection; conservation tillage; intercropping; crop rotation; saving irrigation

(This special issue belongs to the Section Plant Science)

Feature Papers in Medical Research: 4th Edition

edited by

Christian Lehmann

submission deadline 26 Jun 2026 | Viewed by 303 | Submission Open

Keywords: dermatological research; cancer research; cardiovascular research; general medicine; gastroenterological research; hematological research; immunological research; infectious diseases research; metabolism and endocrinology; nervous system research; nursing; pediatrics; pulmonary research; psychiatric research; rehabilitation; renal and urinary research; reproductive research and women's health; rheumatological research; skeletal and muscular research; vision research

(This special issue belongs to the Section Medical Research)

Innovations in Thoracic Medicine: Advancements and Challenges—2nd Edition

edited by Paolo Scanagatta

submission deadline 26 Jun 2026 | Viewed by 74 | Submission Open

Keywords: thoracic medicine; lung cancer; artificial intelligence (AI); minimally invasive intervention; thoracic anesthesia; clinical innovation; technological advances

(This special issue belongs to the Section Medical Research)

Application of Mass Spectrometry-Based Multi-Omics in Biomedical Research

edited by

Young Ah Goo

and

Byoung-Kyu Cho

submission deadline 26 Jun 2026 | Viewed by 63 | Submission Open

Keywords: mass spectrometry; multi-omics; proteomics; metabolomics; lipidomics; mass spectrometry imaging (MSI); biomarker discovery; translational research

(This special issue belongs to the Section Medical Research)

Advanced Technologies and Clinical Practice of Cancer Radiotherapy

edited by

Marcin Balcerzyk

submission deadline 26 Jun 2026 | Viewed by 37 | Submission Open

Keywords: proton therapy; BNCT; in vivo dose verification in radiotherapy; accelerators for radiation therapy; simulation of radiotherapies

(This special issue belongs to the Section Radiobiology and Nuclear Medicine)

Harnessing Mitochondrial Rewiring for Cancer Therapy: Novel Strategies in the Era of Precision Medicine

edited by

Theodoros Rampias

and Maria Sideridou

submission deadline 26 Jun 2026 | Viewed by 25 | Submission Open

Keywords: Oxidative stress; Metabolic rewiring; Carcinogenesis; DNA repair; Cancer therapy; Heteroplasmy

(This special issue belongs to the Section Physiology and Pathology)

Recent Advances in Physiotherapy for Musculoskeletal

edited by

Miguel Ángel Rosety-Rodríguez

and

Jorge Góngora-Rodríguez

submission deadline 30 Jun 2026 | 6 articles | Viewed by 14838 | Submission Open

Keywords: musculoskeletal rehabilitation; emerging technologies; virtual reality; artificial intelligence; inflammatory genetics; physiotherapy; sports medicine; functional recovery

(This special issue belongs to the Section Physiology and Pathology)

The Emerging Role of Microbiota in Health and Diseases

edited by Edyta Juszczuk-Kubiak and Katarzyna Góralska

submission deadline 30 Jun 2026 | 6 articles | Viewed by 11964 | Submission Open

Keywords: microbiota; eubiosis; dysbiosis; microbiota– host interaction; microbiota– gut– brain axis; microbiome; bacteria– fungi interactions; microbiota modification; holobiont; cross-feeding; microbiota related diseases; microbiota functions

(This special issue belongs to the Section Microbiology)

Current Advances in Lung Cancer Diagnosis and Treatment

edited by

Hakyoung Kim

, Daesik Yang and

Zhiwei Hu

submission deadline 30 Jun 2026 | 4 articles | Viewed by 8617 | Submission Open

Keywords: lung cancer; underlying lung disease; radiotherapy; systemic therapy; survival outcomes; complication; biomarkers

(This special issue belongs to the Section Medical Research)

Update on Microalgae Metabolites

edited by

Eduardo Jacob-Lopes

and

Leila Queiroz Zepka

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3577 | Submission Open

Keywords: biosynthesis; culture conditions; bioactive compounds; biological activity; biorefinery; proteins; peptides; antifreeze proteins; enzymes; carbohydrates; exocellular polysaccharides; carbohydrate-binding proteins; lipids; fatty acids; chlorophylls; carotenoids; phycobiliproteins; vitamins; minerals; trace elements; sterols; secondary metabolites; downstream processing; purification; safety; regulatory issues; clinical tests

(This special issue belongs to the Section Microbiology)

Sialic Acid and Sialic Acid Derivatives in Biomedicine

edited by

Paola Rota

and

Marco Piccoli

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3332 | Submission Open

Keywords: sialic acid; drug development; sialidase inhibitors; sialylation; sialidase; biomarker

(This special issue belongs to the Section Physiology and Pathology)

Musculoskeletal Imaging: Innovations in Diagnostics and Interventional Therapies

edited by

Paolo Spinnato

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3214 | Submission Open

Keywords: magnetic resonance imaging; bone and bones; computed tomography; sarcoma; interventional radiology

(This special issue belongs to the Section Medical Research)

Microalgae and Their Biotechnological Potential

edited by

Fantao Kong

, Yi Xin and Yuanxue Liang

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3012 | Submission Open

Keywords: microalgae; biofuels; bioproducts; lipid metabolism; synthetic biology; system engineering

(This special issue belongs to the Section Microbiology)

Latest Updates on Clinical Microbiology and Antimicrobial Resistant Infection

edited by Jun Sung Hong

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2943 | Submission Open

Keywords: enterobacteriaceae; antimicrobial resistance; infection; health

(This special issue belongs to the Section Microbiology)

Pathological and Clinical Updates on Eye Diseases

edited by Pier Luigi Surico and

Rohan Bir Singh

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2232 | Submission Open

Keywords: ophthalmology; eye diseases; gene therapy; ocular surface; ocular immunology; cornea

(This special issue belongs to the Section Medical Research)

Advances in Livestock Breeding, Nutrition and Metabolism

edited by

Imran Khan

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2225 | Submission Open

Keywords: genetic selection; livestock breeding; genome editing; animal nutrition; precision feeding; nutritional additives; feed conversion; metabolism; animal health; sustainability

(This special issue belongs to the Section Animal Science)

Helicobacter pylori: 2nd Edition

edited by

Ovidiu Pop

and

Simona Gurzu

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2044 | Submission Open

Keywords: H. pylori; cancers; antioxidative process; diagnostic methods

(This special issue belongs to the Section Microbiology)

Role of Machine and Deep Learning in Drug Screening

edited by

Shahid Ali

and

Teng Zhou

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1549 | Submission Open

Keywords: machine learning in drug screening; deep learning in drug discovery; virtual screening; molecular docking and dynamics; personalized medicine

(This special issue belongs to the Section Pharmaceutical Science)

Advances in the Glyoxalase Pathway: Implications for Oxidative Stress Management in Cancer Therapy and in Age-Related Disease

edited by

Laura Cianfruglia

and

Salvatore Vaiasicca

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1541 | Submission Open

Keywords: glyoxalase system; methylglyoxal; advanced glycation end-products; dicarbonyl stress; oxidative stress; age-related disease; cancer

(This special issue belongs to the Section Physiology and Pathology)

Research on Gastrointestinal Cancer and Nutritional Health

edited by

Irene Lidoriki

, Adam Mylonakis and Dimitrios Tsapralis

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1418 | Submission Open

Keywords: dietary patterns; gastrointestinal cancer; clinical nutrition; nutritional status; nutritional assessment; metabolism; gastric cancer; esophageal cancer; pancreatic cancer; colorectal cancer

(This special issue belongs to the Section Medical Research)

Channel Proteins and Transporters in Human Health and Disease

edited by

Giorgia Scarpellino

Giorgia Chinigò

and

Roberta De Zio

submission deadline 30 Jun 2026 | Viewed by 1061 | Submission Open

Keywords: channel proteins; transporters; ion channel

(This special issue belongs to the Section Proteins and Proteomics)

Cutting-Edge Research in Rhinology and Allergy: Unraveling Disease Mechanisms and Treatment Innovations

edited by Min-Seok Rha

submission deadline 30 Jun 2026 | 1 articles | Viewed by 558 | Submission Open

Keywords: rhinology; allergy; chronic rhinosinusitis; allergic rhinitis; asthma; precision medicine; clinical immunology; immunopathology; therapeutic innovation

Perspectives on Nutrition and Livestock Health

edited by Liuting Wu, Yan Wang and

Felix Kwame Amevor

submission deadline 30 Jun 2026 | 1 articles | Viewed by 524 | Submission Open

Keywords: nutrition; animal health; animal reproductive; animal welfare; gut microbiome

(This special issue belongs to the Section Animal Science)

Applications of Dermatoscopy in Skin Diseases: 2nd Edition

edited by

Paweł Pietkiewicz

Enzo Errichetti

and

Cristian Navarrete

submission deadline 30 Jun 2026 | 1 articles | Viewed by 498 | Submission Open

Keywords: melanoma; skin cancer; inflammoscopy; trichoscopy; ultraviolet reflectance dermatoscopy; skin of color; basal cell carcinoma; squamous cell carcinoma; nevus; digital dermoscopy

(This special issue belongs to the Section Medical Research)

Vector-Borne Diseases and One Health

edited by

Jeronimo Alencar

, Shayenne Silva and

Michail Kotsyfakis

submission deadline 30 Jun 2026 | 1 articles | Viewed by 427 | Submission Open

Keywords: vector-borne diseases; One Health; malaria; dengue; Zika; chikungunya; yellow fever; West Nile virus; Lyme disease; leishmaniasis; Chagas

(This special issue belongs to the Section Animal Science)

Cranial Base Tumors: Pathogenesis, Diagnosis, and Treatments

edited by

Andrew J. Fishman

and Marcin Szymański

submission deadline 30 Jun 2026 | 1 articles | Viewed by 384 | Submission Open

Keywords: skull base tumors; neuro-oncology; endoscopic surgery; cranial nerve preservation; AI-assisted diagnostics; multidisciplinary management

(This special issue belongs to the Section Medical Research)

Neuroimaging and Integrative Analyses in Psychiatry and Addictive Disorders

edited by Arkadiusz Komorowski

submission deadline 30 Jun 2026 | 1 articles | Viewed by 370 | Submission Open

Keywords: psychiatry; neuroimaging; forensic psychiatry; fMRI; PET; EEG; addiction; substance use disorders (SUD); psychotherapy; treatment-resistant depression (TRD); attention deficit hyperactivity disorder (ADHD)

(This special issue belongs to the Section Physiology and Pathology)

New Advances in the Treatment and Assessment of Temporomandibular Joint Disorders

edited by

Łukasz Rafał Pałka

submission deadline 30 Jun 2026 | Viewed by 332 | Submission Open

Keywords: orofacial dysfunction; multifactorial etiology; advanced diagnostic technologies; biomechanical modeling of TMJ; novel imaging techniques; inflammatory and degenerative changes; interdisciplinary management; conservative therapy approaches; occlusal concepts; splint therapy design; physical therapy regimens; long-term implant treatment outcomes; personalized treatment strategies

(This special issue belongs to the Section Medical Research)

Autoimmune Disorders: From Pathophysiology to Therapeutics

edited by

Giulia Lanzolla

and Chiara Mura

submission deadline 30 Jun 2026 | Viewed by 284 | Submission Open

Keywords: autoimmunity; autoimmune diseases; polyglandular autoimmune syndromes; thyroid autoimmune disease; type 1 diabetes

(This special issue belongs to the Section Physiology and Pathology)

Post-Concussion Syndrome and Functional Neurological Disorder

edited by

Ioannis Asterios Mavroudis

submission deadline 30 Jun 2026 | Viewed by 176 | Submission Open

Keywords: post-concussion syndrome; functional neurological disorder; mild traumatic brain injury; cognitive dysfunction ; neuroimaging; biomarkers; neurorehabilitation

(This special issue belongs to the Section Medical Research)

Placental Spectrum Disorders and Gynecological Oncology

edited by Gianluca Raffaello Damiani

submission deadline 30 Jun 2026 | Viewed by 163 | Submission Open

Keywords: placenta; trophoblastic tumor; mola; tumors; bleeding

(This special issue belongs to the Section Medical Research)

Advances in Bioorganic and Medicinal Chemistry

edited by Sahar Kandil

submission deadline 30 Jun 2026 | Viewed by 150 | Submission Open

Keywords: medicinal chemistry; drug discovery; biological chemistry; therapeutic targets; therapeutic agents; treatment of diseases; new therapeutic strategies

Transplant Medicine: Updates and Current Challenges

edited by Phillipe Abreu

submission deadline 30 Jun 2026 | Viewed by 118 | Submission Open

Keywords: robotic transplantation; organ transplants; transplant oncology

(This special issue belongs to the Section Medical Research)

“Out-of-the-Organics-Box” Reflections On and Scenarios for Life’s Emergence

edited by

Wolfgang Nitschke

submission deadline 30 Jun 2026 | Viewed by 115 | Submission Open

Keywords: emergence of life; thermodynamics; bioenergetics; information theory; early metabolism; metal ions in biochemistry

(This special issue belongs to the Section Origin of Life)

Sleep-Disordered Breathing: Key Pathophysiological Mechanisms and Their Clinical Implications

edited by

Jinkwan Kim

submission deadline 30 Jun 2026 | Viewed by 101 | Submission Open

Keywords: sleep-disordered breathing; sleep fragmentation; inflammation; cardiovascular disease; insulin resistance

(This special issue belongs to the Section Physiology and Pathology)

Physical Rehabilitation for Musculoskeletal Disorders: 2nd Edition

edited by

You Gyoung Yi

submission deadline 30 Jun 2026 | Viewed by 95 | Submission Open

Keywords: physical rehabilitation; musculoskeletal disorders; pain management; range of motion; muscle strengthening; mobility enhancement; physical therapy; manual therapy; AI in rehabilitation

(This special issue belongs to the Section Medical Research)

Advances and Challenges in Urothelial and Prostate Cancer: Toward Precision Urologic Oncology

edited by Sashi S. Kommu

submission deadline 30 Jun 2026 | Viewed by 94 | Submission Open

Keywords: urothelial carcinoma; prostate cancer; immunotherapy; genomics and biomarkers; precision imaging (PSMA PET; mpMRI); targeted therapies (PARP; FGFR; DDR); focal therapy and theranostics; tumour microenvironment; quality of life and survivorship; health disparities in cancer care; artificial intelligence

(This special issue belongs to the Section Medical Research)

Neural Mechanisms of Brain–Computer Interfaces

edited by

Miguel Pais-Vieira

submission deadline 30 Jun 2026 | Viewed by 75 | Submission Open

Keywords: brain– machine interfaces; neurophysiology; somatosensory cortex; motor cortex

(This special issue belongs to the Section Physiology and Pathology)

Mechanisms and Modulation of Pain: From Ion Channels to Translational Therapeutics

edited by Álvaro Yogi

submission deadline 30 Jun 2026 | Viewed by 73 | Submission Open

Keywords: pain; mechanisms; signaling pathways; ion channels; therapeutic targets; neuropathic pain; inflammatory pain; pre-clinical models

(This special issue belongs to the Section Pharmaceutical Science)

Drug Safety and Outcomes in Respiratory and Critical Care Medicine

edited by

Josef Yayan

submission deadline 30 Jun 2026 | Viewed by 63 | Submission Open

Keywords: drug safety; adverse drug reactions; pharmacovigilance; critical care medicine; respiratory diseases; clinical outcomes; intensive care pharmacotherapy; drug– drug interactions

(This special issue belongs to the Section Pharmaceutical Science)

Extracellular Vesicles: Biology, Mechanisms, and Therapies for Cerebrovascular Disorders

edited by Jinju Wang

submission deadline 30 Jun 2026 | Viewed by 52 | Submission Open

Keywords: extracellular vesicles; cerebrovascular disorders; dementia; extracellular vesicle-based therapy

(This special issue belongs to the Section Physiology and Pathology)

Neurodegeneration Across Mechanisms, Epidemiology, and Emerging Therapies: Inflammation, Metabolism, Aging, and Neuromodulation

edited by Julian Benito Leon

submission deadline 30 Jun 2026 | Viewed by 51 | Submission Open

Keywords: neurodegeneration; neuroinflammation; metabolic dysfunction; aging and inflammaging; epidemiology; biomarkers; neuromodulation; transcranial magnetic stimulation (TMS)

(This special issue belongs to the Section Medical Research)

Comprehensive Treatment and Precision Medicine Strategies for Heart Disease

edited by Serge Sicouri

submission deadline 30 Jun 2026 | Viewed by 46 | Submission Open

Keywords: precision medicine; artificial intelligence; risk stratification; machine learning; translational research; cardiovascular outcomes

(This special issue belongs to the Section Medical Research)

Rewiring Bacterial Communication: Extracellular Vesicles and Microbial Signals Across Host Interfaces

edited by Sara Carloni

submission deadline 30 Jun 2026 | Viewed by 35 | Submission Open

Keywords: bacterial extracellular vesicles (bEVs); host– microbe communication; microbiota dynamics; immune modulation; translational applications

(This special issue belongs to the Section Microbiology)

Displaying special issue 351-400 on page 8 of 10.

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