Autoimmune Disorders: From Pathophysiology to Therapeutics
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: closed (30 June 2026) | Viewed by 2565
Editors
2. Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Interests: Graves’ disease; hyperthyroidism; GD extrathyroidal manifestations; thyroid autoimmunity; thyroid disease; Graves’ orbitopathy
Special Issues, Collections and Topics in MDPI journals
2. University Hospital of Cagliari, Cagliari, Italy
Interests: thyroid disease; thyroid autoimmunity; Graves’ disease; Graves orbitopathy; immune check point inhibitors; bone disease; bone development
Special Issue Information
Dear Colleagues,
Autoimmune disorders, characterized by the immune system's misguided recognition and attack on self-antigens, remain a significant challenge in medicine. These diseases, which include conditions such as rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, type 1 diabetes, and thyroid autoimmune disorders, namely autoimmune thyroiditis and Graves’ disease, affect millions worldwide and often lead to chronic disability. Among these conditions, polyglandular autoimmune syndromes (PASs) represent a particularly complex subset, involving the simultaneous dysfunction of multiple endocrine glands, which adds layers of clinical and therapeutic complexity. Despite remarkable progress in understanding the pathophysiology of autoimmunity, much remains to be explored, particularly in bridging the gap between molecular mechanisms and therapeutic applications.
This Special Issue, “Autoimmune Disorders: From Pathophysiology to Therapeutics”, seeks to bring together cutting-edge research and expert reviews that delve into the intricate mechanisms driving autoimmunity and highlight innovative therapeutic strategies. We invite contributions that explore the genetic, epigenetic, and environmental factors influencing autoimmunity, novel biomarkers for diagnosis and disease monitoring, and state-of-the-art interventions, including biologics, small molecules, and immune-modulating therapies.
Our goal is to provide a platform for researchers and clinicians to share insights that advance the field, foster collaboration, and ultimately improve patient outcomes. By addressing both foundational and translational aspects of autoimmune disorders, this Special Issue aims to bridge the bench-to-bedside gap and pave the way for more effective and personalized treatment approaches.
We look forward to receiving your submissions and showcasing groundbreaking work in this critical field.
Dr. Giulia Lanzolla
Dr. Chiara Mura
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- autoimmunity
- autoimmune diseases
- polyglandular autoimmune syndromes
- thyroid autoimmune disease
- type 1 diabetes
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