Current Research on Dermatology: Pathology, Clinical Manifestation, Investigation and Therapy—Third Edition

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: 29 August 2025 | Viewed by 783

Special Issue Editor


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Guest Editor
1. Clinical Department, Dermatology, Faculty of Medicine and Pharmacy, Dunarea de Jos University, Galati, Romania
2. Dermatology Department, Saint Parascheva Clinical Hospital of Infectious Diseases, Galati, Romania
3. Multidisciplinary Integrative Center for Dermatologic Interface Research MIC-DIR, Galati, Romania
Interests: Demodex; endosymbionts; cutaneous microbiome; integrative medicine; optical coherence tomography; dermoscopy; confocal microscopy; cutaneous comorbidities; skin cancer
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Special Issue Information

Dear Colleagues,

Considering recent advances in the field, dermatovenerology has proven to be a specialty of clinical, investigative and therapeutic interest. Medical history and clinical examination, followed by non-invasive imaging, blood tests or the exploration of skin structures and their pathological changes, allow pathologists to better understand, detect and define diseases of the skin. Cutaneous signs and symptoms thus represent a window into the systemic state of the human body. Many diseases thought to be localized to the skin are now considered to be systemically involved in other areas. Each patient is unique, with their own comorbidities and anatomic or physiologic particularities.

Cutaneous skin diseases vary in appearance, evolution and prognosis, as well as in their response to various treatments. The management of skin disease comorbidities requires interdisciplinary collaboration among medical and surgical specialties. Novel treatments are now available for various skin conditions, including surgical, cosmetic and physiotherapeutic procedures. Drugs of both plant and chemical origin can produce systemic or adverse skin reactions. If classical therapy is ineffective or is not tolerated, off-the-label drugs or complementary and alternative medicine methods can be used as part of an integrative medicine treatment.

The new perspectives offered by translational medicine and research on the microbiome, endosymbionts, inflammatory molecules, diagnostics, treatments and observations of comorbidities, complications and their management are improving the standard of skin care, placing it in the context of personalized medicine and care.

This Special Issue of Life will collect and present data on the latest developments in the field. We welcome reviews and research/original articles. Life has no restrictions on the maximum length of research manuscripts, provided that the text is concise and comprehensive. Papers may have two corresponding authors and two first authors at most.

Given that the first and second edition of this Special Issue were a great success, we now invite you to publish in the third edition (https://www.mdpi.com/journal/life/special_issues/Dermatology_research; https://www.mdpi.com/journal/life/special_issues/U96NJI7EDI).

Prof. Dr. Alin Laurentiu Tatu
Guest Editor

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Demodex
  • endosymbionts
  • cutaneous microbiome
  • integrative medicine
  • optical coherence tomography
  • dermoscopy
  • confocal microscopy
  • cutaneous comorbidities keyword
  • inflammatory diseases
  • hair
  • skin cancer
  • comorbidities
  • skin surgery

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Published Papers (1 paper)

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Research

18 pages, 821 KiB  
Article
Psoriasis and Seborrheic Keratoses: Insights from Biologic Therapy and Skin Imaging
by Florin Ciprian Bujoreanu, Diana Sabina Radaschin, Mihail Alexandru Badea, Laura Bujoreanu Bezman, Carmen Pantiș, Carmen Tiutiuca, Liliana Baroiu, Elena Niculeț, Alina Pleșea Condratovici and Alin Laurențiu Tatu
Life 2025, 15(3), 485; https://doi.org/10.3390/life15030485 - 17 Mar 2025
Viewed by 544
Abstract
Psoriasis is one of the most frequent immune-mediated chronic inflammatory cutaneous disease that exerts a considerable psychological impact, including low self-esteem, stigmatization, and depression. In recent years, biologic therapies have substantially transformed the therapeutic landscape for individuals with moderate-to-severe psoriasis, shifting treatment towards [...] Read more.
Psoriasis is one of the most frequent immune-mediated chronic inflammatory cutaneous disease that exerts a considerable psychological impact, including low self-esteem, stigmatization, and depression. In recent years, biologic therapies have substantially transformed the therapeutic landscape for individuals with moderate-to-severe psoriasis, shifting treatment towards a more targeted and personalized approach. Seborrheic keratoses (SKs) are common benign skin lesions, and their association with psoriasis and biologic therapy remains poorly understood. Our retrospective study evaluated a small cohort of patients with moderate-to-severe psoriasis undergoing biologic therapy at a tertiary dermatology center in Southeastern Europe to evaluate potential correlations with SK development. Smokers had fewer SKs, whereas postmenopausal women and osteoporosis patients had significantly higher SK counts, implicating hormonal influences. PUVA therapy was linked to an increased SK count, whereas UVB and methotrexate treatments had a lesser effect. These findings suggest that biologic therapy and systemic factors may influence SK development, emphasizing the need for further prospective research. Full article
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