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Personalized Diagnosis and Treatment in Sports Medicine
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Personalized Diagnosis and Treatment in Sports Medicine

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Personalized Therapy and Drug Delivery".

Deadline for manuscript submissions: 25 June 2026 | Viewed by 997

Special Issue Editors

Dr. Maria Ruberto

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Guest Editor
Department of Education and Sport Sciences, Pegaso Telematic University, 80143 Naples, Italy
Interests: rehabilitation; neurodevelopmental disorders; non-invasive neuromodulation; sports medicine
Dr. Fiorenzo Moscatelli

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Guest Editor
Department of Education and Sport Sciences, Pegaso Telematic University, 80143 Naples, Italy
Interests: exercise interventions and functional adaptations in sedentary adult populations; neuromuscular and physiological responses to physical inactivity and training
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The integration of personalized medicine into sports medicine is driving a paradigm shift toward individualized diagnostic and therapeutic strategies tailored to each athlete’s unique genetic, biomechanical, metabolic, and psychosocial characteristics. This Special Issue of the Journal of Personalized Medicine, titled "Personalized Diagnosis and Treatment in Sports Medicine", seeks to present cutting-edge research and clinical advances that leverage precision medicine to optimize injury prevention, diagnosis, treatment, and performance outcomes.

Emerging technologies—including genomics, proteomics, advanced imaging modalities, motion capture systems, and wearable biosensors—are enabling clinicians and researchers to generate highly detailed athlete profiles. These data, when combined with machine learning and predictive modeling, facilitate early detection of injury risk, stratification of treatment responses, and the design of customized rehabilitation and return-to-play protocols.

We invite contributions that explore innovative diagnostic biomarkers, individualized therapeutic interventions, patient-specific modeling, and digital health solutions. Submissions may address acute or chronic musculoskeletal conditions, neuro-muscular adaptations, recovery monitoring, and performance optimization strategies, particularly when grounded in mechanistic understanding and translational application.

This Special Issue aims to advance the field by promoting interdisciplinary collaboration across orthopedics, sports medicine, physical therapy, biomedical engineering, and computational sciences, contributing to the development of evidence-based, athlete-specific clinical pathways.

Dr. Maria Ruberto
Prof. Dr. Fiorenzo Moscatelli
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • personalized sports medicine
  • athlete-specific diagnostics
  • tailored treatment protocols
  • sports injury prevention
  • biomechanical analysis
  • digital health in athletics
  • wearable health technologies

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Published Papers (1 paper)

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Research

10 pages, 2015 KB  
Article
In Vivo Long Head of the Biceps Tendon Stiffness Varies with Forearm Position During Active Contraction: Implications for Personalized Rehabilitation After SLAP Lesions
by Zade Pederson and Hugo Giambini
J. Pers. Med. 2026, 16(4), 194; https://doi.org/10.3390/jpm16040194 - 1 Apr 2026
Viewed by 719
Abstract
Background/Objectives: Type II superior labrum anterior–posterior (SLAP) lesions of the long head of the biceps (LHB) tendon are associated with excessive tendon loading and are commonly treated surgically using SLAP repair, tenotomy, or tenodesis. These procedures alter musculotendinous length and loading and [...] Read more.
Background/Objectives: Type II superior labrum anterior–posterior (SLAP) lesions of the long head of the biceps (LHB) tendon are associated with excessive tendon loading and are commonly treated surgically using SLAP repair, tenotomy, or tenodesis. These procedures alter musculotendinous length and loading and may affect functional outcomes, including forearm supination strength. Appropriate restoration of tendon tension is critical for favorable muscle adaptation and recovery. Shear wave elastography (SWE) is a non-invasive imaging technique capable of quantifying tissue stiffness as a surrogate for in vivo musculotendinous tension. This study aimed to characterize LHB tendon tension across forearm positions and loading conditions to improve the understanding of functional tendon loading relevant to postoperative activation and rehabilitation. Methods: In this controlled laboratory study, thirteen healthy female volunteers without shoulder pathology were assessed using SWE with the elbow positioned at 90° flexion. LHB tendon tension was measured in forearm pronation and supination under passive, active (unresisted), and weighted conditions. Paired t-tests were used to compare forearm positions within each loading condition. Results: LHB tendon tension was significantly greater during active and weighted conditions compared with passive loading in the pronated position (p < 0.05). During active contraction, tendon tension was significantly lower in supination than pronation (p < 0.05), whereas no positional differences were observed under passive or weighted conditions. Relative to passive loading, tendon tension increased by approximately 18.2% and 89.2% in supination, and 67.0% and 97.9% in pronation during active and weighted conditions, respectively. Conclusions: Forearm position selectively influences LHB tendon tension during active, unresisted contraction. Forearm orientation affected LHB tendon stiffness primarily during active, unweighted contraction, where pronation resulted in higher stiffness than supination. On the other hand, stiffness outcomes measured during passive and weighted positions were comparable between forearm orientations, indicating that positional effects are most evident when tendon loading is primarily muscle-driven. These findings highlight the relevance of forearm positioning during early postoperative activation and provide normative in vivo reference data to inform personalized rehabilitation strategies and future investigations of postoperative tendon loading following SLAP lesion treatment. Full article
(This article belongs to the Special Issue Personalized Diagnosis and Treatment in Sports Medicine)
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