Knee Injuries: Personalized Diagnosis, Treatment and Management
A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Personalized Therapy and Drug Delivery".
Deadline for manuscript submissions: 30 June 2026
Special Issue Editors
Interests: hip; hip and knee replacement; knee injury; arthroscopy
Interests: hip and knee primary arthroplasty; hip and knee revision arthroplasty; periprosthetic joint infection; periprosthetic fracture complications
Special Issue Information
Dear Colleagues,
Knee injuries can affect the surrounding bones, cartilage, and ligaments, thereby impacting people's normal activities. Among these, knee osteoarthritis (OA) is a progressive degenerative joint disease characterized by the breakdown of cartilage, subchondral bone remodeling, synovial inflammation, and the formation of osteophytes. It is one of the leading causes of pain, disability, and reduced quality of life. When conservative management—including pharmacological treatment, physical therapy, and intra-articular injections—fails, total knee arthroplasty (TKA) becomes the definitive treatment.
TKA is a highly effective surgical procedure that aims to relieve pain, restore function, and improve mobility by replacing the damaged surfaces with prosthetic components. TKA has shown excellent long-term outcomes. However, as with any major surgery, it carries the risk of complications. These may include infection, deep vein thrombosis, aseptic loosening, periprosthetic fracture, stiffness, neurovascular injury, postoperative pain, and dissatisfaction due to unmet expectations or unexplained discomfort.
Understanding the pathophysiology of knee OA, the indications for TKA, and the potential complications is essential for selecting patients appropriately, providing preoperative counseling, and managing postoperative outcomes to optimize clinical outcomes.
This Special Issue aims to promote the development of diagnosis and treatment models of knee injuries in the era of personalized medicine, promote the transformation from basic research to clinical practice, and ultimately improve the quality of life of patients.
We welcome scholars to submit review articles and original research articles related to knee injuries and personalized medicine.
Dr. Gavin Wood
Guest Editor
Dr. Fernando Diaz Dilernia
Guest Editor Assistant
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- knee osteoarthritis
- personalized medicine
- precision diagnosis
- partial and total knee arthroplasty
- periprosthetic frac-ture
- complications
- functional outcomes
- instability
- survivorship
- periprosthetic joint infection
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