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Knee Injuries: Personalized Diagnosis, Treatment and Management
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Knee Injuries: Personalized Diagnosis, Treatment and Management

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Personalized Therapy and Drug Delivery".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 1314

Special Issue Editors

Dr. Gavin Wood

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Guest Editor
Adult Hip and Knee Reconstructive Surgery, Division of Orthopaedic Surgery, Department of Surgery, Queen’s University & Kingston Health Sciences Centre, Kingston, ON K7L 2V7, Canada
Interests: hip; hip and knee replacement; knee injury; arthroscopy
Dr. Fernando Diaz Dilernia

E-Mail
Guest Editor Assistant
Division of Orthopaedic Surgery, Department of Surgery, Queen's University & Kingston Health Sciences Centre, Kingston, ON K7L 2V7, Canada
Interests: hip and knee primary arthroplasty; hip and knee revision arthroplasty; periprosthetic joint infection; periprosthetic fracture complications

Special Issue Information

Dear Colleagues,

Knee injuries can affect the surrounding bones, cartilage, and ligaments, thereby impacting people's normal activities. Among these, knee osteoarthritis (OA) is a progressive degenerative joint disease characterized by the breakdown of cartilage, subchondral bone remodeling, synovial inflammation, and the formation of osteophytes. It is one of the leading causes of pain, disability, and reduced quality of life. When conservative management—including pharmacological treatment, physical therapy, and intra-articular injections—fails, total knee arthroplasty (TKA) becomes the definitive treatment.

TKA is a highly effective surgical procedure that aims to relieve pain, restore function, and improve mobility by replacing the damaged surfaces with prosthetic components. TKA has shown excellent long-term outcomes. However, as with any major surgery, it carries the risk of complications. These may include infection, deep vein thrombosis, aseptic loosening, periprosthetic fracture, stiffness, neurovascular injury, postoperative pain, and dissatisfaction due to unmet expectations or unexplained discomfort.

Understanding the pathophysiology of knee OA, the indications for TKA, and the potential complications is essential for selecting patients appropriately, providing preoperative counseling, and managing postoperative outcomes to optimize clinical outcomes.

This Special Issue aims to promote the development of diagnosis and treatment models of knee injuries in the era of personalized medicine, promote the transformation from basic research to clinical practice, and ultimately improve the quality of life of patients.

We welcome scholars to submit review articles and original research articles related to knee injuries and personalized medicine.

Dr. Gavin Wood
Guest Editor

Dr. Fernando Diaz Dilernia
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • knee osteoarthritis
  • personalized medicine
  • precision diagnosis
  • partial and total knee arthroplasty
  • periprosthetic frac-ture
  • complications
  • functional outcomes
  • instability
  • survivorship
  • periprosthetic joint infection

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

11 pages, 224 KB  
Article
Personalized Surgical Decision-Making in Meniscal Tears: Short-Term Outcomes of Repair vs. Partial Meniscectomy in Mongolian Patients
by Orgil Zorigtbaatar, Nomin-Erdene Minjuurdorj, Baatarjav Sosor, Gonchigsuren Dagvasumberel, Bayasgalan Gombojav and Naranbat Lkhagvasuren
J. Pers. Med. 2025, 15(12), 578; https://doi.org/10.3390/jpm15120578 - 28 Nov 2025
Viewed by 1059
Abstract
Objectives: Arthroscopic meniscal surgery (AMS) is one of the most common orthopedic procedures worldwide, and its prevalence has been steadily increasing. In this study, we aimed to compare the short-term clinical outcomes (STCOs) and patient-reported outcome measures (PROMs) with anxiety and satisfaction [...] Read more.
Objectives: Arthroscopic meniscal surgery (AMS) is one of the most common orthopedic procedures worldwide, and its prevalence has been steadily increasing. In this study, we aimed to compare the short-term clinical outcomes (STCOs) and patient-reported outcome measures (PROMs) with anxiety and satisfaction in Mongolian patients. Methods: A prospective cohort study involved 103 patients who underwent arthroscopic knee surgery at The National Trauma Orthopedic Research Center and Grandmed Hospital in Mongolia between 2020 and 2023. STCO and PROM were calculated for the Knee Injury and Osteoarthritis Outcome Score (KOOS) subscores, the visual analog scale was assessed for pain (VAS), and Knee Range of Motion (ROM), Measures of Anxiety State-Trait Anxiety Inventory (STAI), and The Surgical Satisfaction Questionnaire (SSQ-8) were also used. Results: Out of 103 patients (69 for partial meniscectomy and 34 for meniscal repair), KOOSs improved significantly from pre-operative to post-operative levels. The Koos subscores for pain were 57.93 ± 12.58 pre-operatively and 80.93 ± 5.70 post-operatively; Koos subscores for Symptoms (KOOS Sx) were 54.13 ± 12.73, 80.27 ± 6.22; Koos subscores for Activities of Daily Living (KOOS ADL) were 61.28 ± 13.19, 79.61 ± 4.91; Koos subscores for Sports/Recreation (KOOS SR) were 42.28 ± 13.21, 72.04 ± 6.88; and Koos subscores for Quality of Life (KOOS QOL) were 45.08 ± 12.46, 77.85 ± 7.96. On the other hand, the pre-operative and post-operative results of the STAI were not significant (46.03 ± 8.2 vs. 39.59 ± 7.13, p = 0.781). Conclusions: In the present study, we elucidated patient- and injury-specific factors that may guide personalized surgical decision-making in Mongolian patients. Our findings suggest that AMS is a viable option for alleviating pain and enhancing function in the short term for patients with meniscal tears. The high PROMs and satisfaction scores reflect good-to-excellent results, and meniscal repair was associated with better outcome scores. While pre-operative anxiety levels were high, they decreased after surgery, although they did not entirely disappear. Full article
(This article belongs to the Special Issue Knee Injuries: Personalized Diagnosis, Treatment and Management)
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