Cutting-Edge Innovations in Hip and Knee Joint Replacement

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".

Deadline for manuscript submissions: 27 May 2026 | Viewed by 404

Special Issue Editors


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Guest Editor
Department of Orthopaedics, University of Florence, 50121 Firenze, Italy
Interests: adult hip and knee reconstructions (primary and revision surgery); robot-assisted surgery; personalized surgery; minimally invasive surgery; osteotomies around the knee
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E-Mail Website
Guest Editor
Department of Orthopaedics, University of Florence, 50121 Firenze, Italy
Interests: knee surgery; orthopedic surgery; hip replacement

Special Issue Information

Dear Colleagues,

Over the past two decades, primary and revision hip and knee replacement surgeries have achieved impressive success rates. However, it is essential to acknowledge that a significant number of patients do not fully benefit from these procedures.

In response, the field has seen remarkable innovations designed to enhance outcomes and patient satisfaction. Advances such as enhanced preoperative planning technologies, robot-assisted surgery, patient-specific instrumentation (PSI), custom-made/personalized implants, and the integration of mixed/augmented reality and artificial intelligence (AI) during surgery are being developed to reduce failure rates and improve clinical outcomes.

Despite these promising innovations, the greatest challenge remains: none of these advancements have consistently demonstrated a significant improvement in patient satisfaction or reduced failure rates.

In light of these challenges, our Special Issue will focus on the most prevalent trends in primary and revision hip and knee replacements, evaluating future solutions and the impact of recent technological advancements.

We invite you to contribute an original article as well as a review paper to our Special Issue.

Best regards,

Dr. Matteo Innocenti
Prof. Dr. Roberto Civinini
Guest Editors

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Keywords

  • primary or revision total hip arthroplasty
  • hip resurfacing
  • primary or revision total knee arthroplasty
  • unicompartimental/bicompartimental knee replacement
  • patient-specific instrumentation (PSI)
  • custom-made/personalized implants
  • robot-assisted surgery
  • mixed/augmented reality
  • artificial intelligence (AI)
  • personalized surgery

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Published Papers (1 paper)

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Research

10 pages, 328 KiB  
Article
Robotic-Assisted Joint Line Preserving Unicompartmental Knee Arthroplasty Positioning Among Octogenarians
by Filippo Leggieri, Fernando Nahuel Martín Cocilova, Alessandro Civinini, Davide Stimolo, Roberto Civinini and Matteo Innocenti
J. Pers. Med. 2025, 15(8), 362; https://doi.org/10.3390/jpm15080362 - 8 Aug 2025
Abstract
Introduction: Octogenarians undergoing unicompartmental knee arthroplasty (UKA) face increased risks of complications due to reduced bone support following osteoporosis. The aim of this study was to describe our preferred technique to balance robotic-assisted UKA in this specific patient population and to present [...] Read more.
Introduction: Octogenarians undergoing unicompartmental knee arthroplasty (UKA) face increased risks of complications due to reduced bone support following osteoporosis. The aim of this study was to describe our preferred technique to balance robotic-assisted UKA in this specific patient population and to present its results. Methods: This retrospective analysis of prospectively collected data examined 121 consecutive octogenarian patients (median age 84 years, IQR 82–86) who underwent robotic-assisted medial UKA between September 2018 and December 2022 with ≥24 months follow-up. Patients aged ≤80 years, with ≤2 years of follow-up, or without informed consent were excluded. Data collection included radiographic measurements (HKA, LDFA, MPTA, joint line height), patient-reported outcome measures (Oxford Knee Score, Knee Society Score), and complications. Statistical analysis employed descriptive statistics, paired t-tests, Cohen’s d for effect sizes, and the McNemar test for categorical variables. Results: The hip–knee–ankle angle improved significantly from 174.43° to 178.04° (mean difference 3.61°, 95% CI 3.13–4.09, p < 0.001). Patient-reported outcomes demonstrated substantial improvements: the Knee Society Score increased by 83.09 points (95% CI 79.76–86.42, p < 0.001, Cohen’s d = 4.53), and the Oxford Knee Score increased by 17.09 points (95% CI 15.42–18.76, p < 0.001), with both exceeding minimal clinically important differences. Only 7.4% (9/121) of cases exhibited joint line lowering of >2 mm, with 1.7% (2/121) having both post-operative HKA <175° and joint line lowering of >2 mm. The implant survival rate was 100% with minimal complications, including two conservatively managed tibial plateau fractures and two cases of wound dehiscence with no further surgery needed. Conclusions: Robotic-assisted medial UKA can consistently preserve joint line height while achieving excellent alignment correction and clinical outcomes in octogenarians, potentially addressing failure risks in this specific population. Full article
(This article belongs to the Special Issue Cutting-Edge Innovations in Hip and Knee Joint Replacement)
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