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Special Issues
Novel Challenges and Advances in Respiratory Diseases
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Novel Challenges and Advances in Respiratory Diseases

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Mechanisms of Diseases".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 951

Special Issue Editor

Dr. Vasiliki E. Georgakopoulou

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Guest Editor
Department of Pathophysiology, Laiko General Hospital, National and Kapodistrian University of Athens, 11527 Athens, Greece
Interests: respiratory medicine; pathophysiology; respiratory infections; bronchoscopy; viruses; COVID-19; biostatistics

Special Issue Information

Dear Colleagues,

This Special Issue, entitled “Novel Challenges and Advances in Respiratory Diseases”, aims to offer a comprehensive exploration of the latest research and advancements in the field of respiratory medicine. With a particular focus on innovative approaches, breakthrough treatments, and cutting-edge technologies, this issue aims to shed light on the diverse spectrum of respiratory conditions and their management strategies. From investigating novel therapeutic interventions to elucidating the underlying mechanisms of respiratory diseases, the articles in this Special Issue provide valuable insights into understanding, diagnosing, and treating various pulmonary disorders. Additionally, given the unprecedented challenges posed by emerging pathogens like COVID-19, this issue also addresses the impact of such global health crises on respiratory health and healthcare systems. By covering topics such as immunotherapy, precision medicine, respiratory infections, and airway diseases, this Special Issue serves as a valuable resource for researchers, clinicians, and policymakers striving to advance the field of respiratory medicine and improve patient outcomes.

Dr. Vasiliki E. Georgakopoulou
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • respiratory diseases
  • pulmonary disorders
  • lung health
  • novel therapies
  • diagnostic advancements
  • COVID-19 impact
  • immunotherapy
  • respiratory infections
  • airway diseases
  • precision medicine

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

14 pages, 991 KiB  
Article
Association Between Amerindian Ancestry and Chronic Obstructive Pulmonary Disease in the Chilean Mixed Population
by Vicente Silva, Andrea Canals and Lucia Cifuentes
J. Pers. Med. 2025, 15(4), 137; https://doi.org/10.3390/jpm15040137 - 31 Mar 2025
Viewed by 574
Abstract
Background/Objectives: Chronic Obstructive Pulmonary Disease (COPD) is one of the most common chronic non-communicable diseases in adults. The most critical risk factors are tobacco and air pollution. The familial aggregation of this disease and the fact that only 15–20% of smokers develop [...] Read more.
Background/Objectives: Chronic Obstructive Pulmonary Disease (COPD) is one of the most common chronic non-communicable diseases in adults. The most critical risk factors are tobacco and air pollution. The familial aggregation of this disease and the fact that only 15–20% of smokers develop COPD demonstrate the existence of an individual susceptibility that would depend on genetic factors. The already-known susceptibility genomic variants explain only about 38% of the heritability of COPD. The present work analyzes the relationship between the percentage of Amerindian genomic ancestry of Chileans with morbidity and mortality of Chronic Obstructive Pulmonary Disease (COPD), adjusting for socioeconomic and environmental variables. Methods: We rely on the estimates of genomic ancestry percentages obtained in the Chilegenomico project in urban Chileans from 39 communes along eight regions of the country from north to south. From the public databases of the Departamento de Estadísticas e Información en Salud (DEIS) of the Chilean Ministry of Health, we obtained mortality rates and hospital discharge rates. We incorporated adjustment variables (communal data) obtained from other public databases. We performed correlation analyses and fitted negative binomial regression models to examine the association between Amerindian ancestries and COPD statistics. Results: A positive and significant association between Mapuche ancestry and hospital discharge and mortality rates for COPD was found in both simple and multiple analyses. In contrast, we found a negative and significant association between the percentage of Aymara genomic ancestry and COPD mortality rates. Conclusions: The levels of Mapuche and Aymara genomic ancestries have different and contrasting significant associations with COPD susceptibility and mortality in the Chilean mixed population. Full article
(This article belongs to the Special Issue Novel Challenges and Advances in Respiratory Diseases)
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