Due to scheduled maintenance work on our servers, there may be short service disruptions on this website between 11:00 and 12:00 CEST on March 28th.

Exploring Interventional Radiology: New Advances and Prospects

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Methodology, Drug and Device Discovery".

Deadline for manuscript submissions: 31 May 2026 | Viewed by 6430

Special Issue Editor


E-Mail Website
Guest Editor

Special Issue Information

Dear Colleagues,

This Special Issue of the Journal of Personalized Medicine is dedicated to interventional radiologists (IRs) seeking to showcase cutting-edge techniques, innovative approaches, and emerging challenges within the field of interventional radiology. We invite contributions that not only focus on novel treatments but also offer broader perspectives on the evolution and future of IR as a specialty.

The scope of this Special Issue is not limited to therapeutic advancements. It encourages interdisciplinary and transversal contributions that address the holistic development of interventional radiology, including epidemiological studies, economic evaluations, and strategies for tackling the challenges facing the specialty today. We welcome research articles or reviews that provide new insights into optimizing clinical practice, as well as broader discussions on how to advance IR in a rapidly changing healthcare landscape.

This Special Issue aims to serve as a platform for the IR community to share knowledge, explore new perspectives, and collectively shape the future of interventional radiology.

Prof. Dr. Julien Frandon
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • interventional radiology
  • embolization
  • innovative techniques
  • minimally invasive procedures
  • long-term safety
  • prostate cancer
  • vascular anomalies
  • clinical outcomes
  • health economics
  • epidemiology

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (5 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

Jump to: Other

10 pages, 1581 KB  
Article
A New Generation of Eco-Designed Embolic Agents: Towards Sustainable and Personalized Interventional Radiology
by Alexis Ruimy, Thibault Agripnidis, Julien Panneau, Johanna Nguyen, Farouk Tradi, Thierry Marx, Raphaël Haumont, Pauline Brige, Benjamin Guillet and Vincent Vidal
J. Pers. Med. 2026, 16(2), 64; https://doi.org/10.3390/jpm16020064 - 29 Jan 2026
Viewed by 376
Abstract
Background: Embolization is a key therapeutic option in interventional radiology for the management of acute arterial bleeding and solid organ injuries. While various embolic agents exist, there is a persistent clinical need for materials that are not only highly effective but also biocompatible, [...] Read more.
Background: Embolization is a key therapeutic option in interventional radiology for the management of acute arterial bleeding and solid organ injuries. While various embolic agents exist, there is a persistent clinical need for materials that are not only highly effective but also biocompatible, easy to deliver, and cost-effective. We aim to evaluate a new eco-friendly dry foam agar-based embolization agent (ABEA) in an uncontrolled solid organ hemorrhage model. Material and Methods: Ten pigs underwent a controlled splenic injury. After a 5 min free-bleeding period, five pigs were treated with splenic artery ABEA embolization, while the remaining five received no treatment and served as the control group. Follow-up angiography was performed immediately after embolization and at 5 and 15 min in the treated pigs. Mean arterial pressures and average blood loss volumes were evaluated for 120 min. Results: The control group showed continuous blood loss, leading to a significantly higher total blood loss than the ABEA-treated group (1451 mL vs. 611 mL at 120 min, p < 0.05). Mean arterial pressure (MAP) remained below the hemorrhagic shock threshold throughout the procedure in the control group, validating the model of uncontrolled hemorrhage. In addition, a significant stabilization of MAP was observed in treated pigs, remaining above the critical level of hemorrhagic shock and differed significantly from control group values. Conclusions: Embolization with ABEA maintained MAP above critical levels and significantly reduced blood loss volume in a hemorrhagic model. These results support the technical feasibility and short-term hemostatic performance of ABEA in an acute setting. While preliminary, this proof-of-concept has provided the basis for a validated clinical study currently underway to evaluate its effectiveness and safety in human patients. Full article
(This article belongs to the Special Issue Exploring Interventional Radiology: New Advances and Prospects)
Show Figures

Figure 1

11 pages, 2216 KB  
Article
Innovative Approach to Embolization of Pelvic Varices Using Endovaginal Guidance: Methodology and Early Outcomes
by Eva Fourage-Jambon, Rayann Soueidan, Hamza Sawalha, Yassine Lamfichekh, Benjamin Linares, Hugo Hans, Mathieu David, Isabelle Molina-Andreo, Charlotte Douchez, Nicolas Pangon, Yann Le Bras, Rim Maaloum and Clément Marcelin
J. Pers. Med. 2025, 15(10), 500; https://doi.org/10.3390/jpm15100500 - 17 Oct 2025
Cited by 1 | Viewed by 1161
Abstract
Objective: To retrospectively assess the safety and efficacy of endovaginal guidance for embolizing perivaginal varices associated with persistent localized symptoms, including dyspareunia and postcoital pain. Methods: From February 2024 to January 2025, 10 women (median age: 36 years, range: 23–45) underwent pelvic embolization [...] Read more.
Objective: To retrospectively assess the safety and efficacy of endovaginal guidance for embolizing perivaginal varices associated with persistent localized symptoms, including dyspareunia and postcoital pain. Methods: From February 2024 to January 2025, 10 women (median age: 36 years, range: 23–45) underwent pelvic embolization using endovaginal guidance. Eight patients had already undergone endovascular embolization, with persistent perivaginal varices that were inaccessible by this approach, accompanied by dyspareunia or postcoital pain. Primary efficacy was assessed three months post-embolization, defined as a Visual Analog Scale (VAS) score of <2 and a ≥50% decrease. Outcomes were assessed through clinical and imaging follow-up. Results: Technical efficacy was achieved in all procedures (100%). Embolization was performed using Glubran/Lipiodol in eight cases (80%) and Onyx® in two cases (20%). The primary efficacy of the procedures was 90.0% (9 out of 10 cases). A reduction in dyspareunia and postcoital pain was observed, with median VAS scores decreasing to one and zero, respectively, compared to initial scores of seven and seven (p = 0.002 and p = 0.016) and to scores after endovascular embolization to five and five (p = 0.004 and p = 0.016). No major complications were recorded. Imaging follow-up showed a significant reduction in perivaginal varicosities in all cases. Conclusions: Endovaginal guidance proves to be a fast and effective technique for the embolization of perivaginal varices, highlighting its integration into the principles of personalized medicine. Full article
(This article belongs to the Special Issue Exploring Interventional Radiology: New Advances and Prospects)
Show Figures

Graphical abstract

Other

Jump to: Research

13 pages, 1862 KB  
Technical Note
Beyond Strict Physics: Using Poiseuille’s Law as a Practical Framework to Optimize and Personalize Cementoplasty
by Sylvain Grange, Rémi Grange, Vincent Habouzit, Maxime Pastor, Louis-Martin Boucher, Jean-Pierre Pelage, Natalia Gorelik and Nicolas Stacoffe
J. Pers. Med. 2026, 16(1), 41; https://doi.org/10.3390/jpm16010041 - 8 Jan 2026
Viewed by 482
Abstract
Background/Objectives: Poiseuille’s law describes the influence of radius, length, viscosity, and pressure on the flow of Newtonian fluids. Although bone cement is a non-Newtonian, shear-thinning, and polymerizing material that does not comply with this law in any predictive or quantitative sense, its qualitative [...] Read more.
Background/Objectives: Poiseuille’s law describes the influence of radius, length, viscosity, and pressure on the flow of Newtonian fluids. Although bone cement is a non-Newtonian, shear-thinning, and polymerizing material that does not comply with this law in any predictive or quantitative sense, its qualitative principles may offer a didactic framework for understanding factors that affect injectability during cementoplasty. The objective of this Technical Note is to provide an educational and conceptual interpretation of Poiseuille’s law as it relates to trocar selection, cement behavior, and procedural planning. Methods: This work presents theoretical calculations based on the r4/L component of Poiseuille’s equation, using manufacturer-specified internal radii for commonly used trocars. Relative flow rates were computed as r4/L ratios normalized to a 13-gauge, 15 cm trocar. Conceptual viscosity profiles illustrate qualitative differences among cements over time. A representative, fully anonymized clinical example is provided to illustrate the integration of these conceptual principles into practice. No experimental measurements were performed. Results: Theoretical calculations show that trocar radius has the strongest influence on theoretical flow, with an exponential effect (r4), whereas increasing trocar length proportionally reduces flow. Conceptual viscosity curves demonstrate the rapid rise in viscosity during polymerization and highlight the importance of timing and cement selection. The clinical example illustrates how trocar choice, access planning, and cement viscosity are adapted to lesion morphology and cortical integrity. Conclusions: Poiseuille’s law cannot model or predict bone cement behavior and has no procedural or clinical validity in cementoplasty. Its use in this Technical Note is strictly educational, providing a qualitative framework to illustrate general relationships between equipment characteristics, viscosity evolution, and resistance during injection, without offering clinical guidance or implying any impact on procedural planning, safety, or outcomes. Full article
(This article belongs to the Special Issue Exploring Interventional Radiology: New Advances and Prospects)
Show Figures

Figure 1

12 pages, 1220 KB  
Case Report
Pathophysiology of Chylous Anasarca Caused by Lymphatic Occlusion: A Case Report and Review of the Literature
by Antoine Mathivet, Martin Bertrand, Isabelle Quere, Jean-Christophe Gris, Julien Ghelfi and Julien Frandon
J. Pers. Med. 2025, 15(6), 216; https://doi.org/10.3390/jpm15060216 - 26 May 2025
Cited by 1 | Viewed by 1566
Abstract
Objective: The aim of this study was to propose a pathophysiological hypothesis for the occurrence of non-traumatic chylous effusions and Central Conducting Lymphatic Anomalies (CCLAs) related to lymphatic occlusion. Methods: We investigated the case of a 39-year-old woman managed at Nîmes University [...] Read more.
Objective: The aim of this study was to propose a pathophysiological hypothesis for the occurrence of non-traumatic chylous effusions and Central Conducting Lymphatic Anomalies (CCLAs) related to lymphatic occlusion. Methods: We investigated the case of a 39-year-old woman managed at Nîmes University Hospital for chylous anasarca related to an endoluminal lymphatic occlusion. We then conducted a comprehensive review of the literature on CCLAs. Results: Lymphatic drainage is a dynamic process. Obstacles to lymphatic drainage via the thoracic duct can lead to chylous anasarca, depending on where the obstruction is. Lymphatic occlusion seems to be an explanation for certain CCLAs. Conclusions: Understanding CCLAs via the theory of lymph occlusion opens the way to new therapeutic options, but requires further investigation in order to personalize the patient’s treatment. Full article
(This article belongs to the Special Issue Exploring Interventional Radiology: New Advances and Prospects)
Show Figures

Figure 1

13 pages, 1881 KB  
Systematic Review
Percutaneous Magnetic Resonance Imaging-Guided Focal Laser Ablation (MRI-FLA) of Prostate Tumors: A Systematic Review and Network Meta-Analysis
by Clément Marcelin, Clément Klein, Grégoire Robert, Franck Bladou, Nicolas Grenier and Eva Jambon
J. Pers. Med. 2024, 14(12), 1146; https://doi.org/10.3390/jpm14121146 - 10 Dec 2024
Cited by 2 | Viewed by 1902
Abstract
Background/Objectives: MRI-guided focal laser ablation (MRI-FLA) is an emerging minimally invasive technique for treating localized prostate tumors, aiming to provide effective cancer control while minimizing side effects. This meta-analysis systematically evaluates the clinical outcomes, technical efficacy, and complication rates associated with MRI-FLA to [...] Read more.
Background/Objectives: MRI-guided focal laser ablation (MRI-FLA) is an emerging minimally invasive technique for treating localized prostate tumors, aiming to provide effective cancer control while minimizing side effects. This meta-analysis systematically evaluates the clinical outcomes, technical efficacy, and complication rates associated with MRI-FLA to better understand its therapeutic potential and safety profile in prostate cancer management. Methods: In July 2024, PubMed (MEDLINE) was searched for eligible trials using the PRISMA guidelines. The primary outcome was residual disease (RD). The secondary outcomes were technical efficacy, progression to metastatic disease, cancer-specific mortality, complications, and decreases in the prostate-specific antigen (PSA) level. Results: Nine clinical trials involving 296 patients with prostate tumors treated via MRI-FLA were analyzed. A random effects model showed that the overall RD prevalence after ablation was 20.37% (12.56–29.28%; p = 0.03) and the cancer-free survival rate was 75.62% (64.88–85.10%). The rate of major and minor adverse effects was 14.26% (0.61–37.3%, p < 0.01). Conclusions: MRI-FLA is safe, feasible, and effective, although further trials are required. Full article
(This article belongs to the Special Issue Exploring Interventional Radiology: New Advances and Prospects)
Show Figures

Figure 1

Back to TopTop