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Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Knee Injuries: Personalized Diagnosis, Treatment and Management

edited by Gavin Wood and Fernando Diaz Dilernia

submission deadline 30 Jun 2026 | 1 articles | Viewed by 372 | Submission Open

Keywords: knee osteoarthritis; personalized medicine; precision diagnosis; partial and total knee arthroplasty; periprosthetic frac-ture; complications; functional outcomes; instability; survivorship; periprosthetic joint infection

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Minimally Invasive Thoracic Surgery: Risk Assessment and Personalized Perioperative Management

edited by

Marco Andolfi

and Vannucci Jacopo

submission deadline 30 Jun 2026 | Viewed by 344 | Submission Open

Keywords: VATS; ERAS; sublobar resection; risk assessment; minimally invasive thoracic surgery

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Bioinformatics and Computational Biology in Personalized Medicine

edited by

Umar Niazi

submission deadline 30 Jun 2026 | Viewed by 165 | Submission Open

Keywords: bioinformatics; computational biology; artificial intelligence; deep learning; machine learning; personalized medicine; patient stratification; multi-omics data integration; biomarkers; oncology informatics; clinical trial data; causal inference; non-randomized studies; observational studies; clinical research informatics

(This special issue belongs to the Section Omics/Informatics)

Personalized Prevention and Treatment of Cardiovascular Diseases

edited by

Daniela Cornelia Lazăr

and

Vladiana Turi

submission deadline 30 Jun 2026 | 1 articles | Viewed by 151 | Submission Open

Keywords: precision medicine in cardiology; cardiovascular risk stratification; personalized therapeutics; omics technologies in CVD; digital health and cardiovascular care; lifestyle interventions for CVD; arterial stiffness and hypertension; biomarkers for cardiovascular diseases

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Anesthesiology and Pain Management in Clinical Medicine: 2nd Edition

edited by

Paolo Formenti

submission deadline 30 Jun 2026 | Viewed by 129 | Submission Open

Keywords: anesthesiology; pain management; clinical medicine; pharmacology; innovative techniques; evidence-based practices

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Medicine in Orthopedics and Traumatology: Updates and Challenges

edited by Jan Reinhard and Melanie Ardelt

submission deadline 30 Jun 2026 | Viewed by 92 | Submission Open

Keywords: personalized lumbar spine surgery; patient-specific implants in endoprosthetics; targeted drug delivery in spine and joint surgery; precision medicine in degenerative lumbar disorders; computer-assisted surgical planning; risk-adapted strategies in endoprosthetics; individualized rehabilitation after joint replacement; functional optimization in lumbar fusion and arthroplasty

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Mental Health: Diagnosis, Therapeutic Intervention and Patient Management in the Era of Personalized Medicine

edited by

Ciprian Bacila

and

Mihnea Costin Manea

submission deadline 30 Jun 2026 | Viewed by 60 | Submission Open

Keywords: therapeutic interventions; patient management; personalized medicine; digital psychiatry; multidisciplinary care teams; com-munity mental health; affective disorders; psychotic disorders

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Precision Medicine in Neurodevelopmental Disorders: Challenges and Opportunities

edited by Song-Yu Yang, Xue-Ying He and Manfred Philipp

submission deadline 1 Jul 2026 | 1 articles | Viewed by 1487 | Submission Open

Keywords: intellectual disability; inborn metabolic disorders; X-linked disorders; retarded growth; mitochondrial diseases; genetic and genomic disorders

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

New Insight into Aging and Geriatric Syndromes: Clinical Updates and Perspectives

edited by

Vittorio Dibello

Francesco Panza

and

Vincenzo Solfrizzi

submission deadline 10 Jul 2026 | 9 articles | Viewed by 26263 | Submission Open

Keywords: gerodontology; dementia; mild cognitive impairment (MCI); frontotemporal dementia; frailty; late-life depression; sarcopenia; sensorial impairments; multimorbidity; oral frailty; longevity; biological aging

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Technologies in Plastic, Reconstructive and Aesthetic Surgery: From Imaging to Regeneration

edited by

Dominik Walczak

submission deadline 10 Jul 2026 | Viewed by 81 | Submission Open

Keywords: personalized surgery; plastic and reconstructive surgery; point-of-care ultrasound; 3D printing; digital surgical planning; regenerative medicine; biomaterials; artificial organs

(This special issue belongs to the Section Regenerative Medicine and Therapeutics)

Combating Antimicrobial Resistance: Translational Science to Clinical Practice

edited by Giovanni Gherardi and Roberta Creti

submission deadline 15 Jul 2026 | Viewed by 75 | Submission Open

Keywords: antimicrobial resistance (AMR); One Health approach; new antibacterial strategies; antimicrobial and diagnostic stewardship

(This special issue belongs to the Section Omics/Informatics)

AI-BioEng: Smart Diagnostics and Therapeutic Innovations in Biomedical Engineering

edited by

Antonio Pallotti

submission deadline 15 Jul 2026 | Viewed by 61 | Submission Open

Keywords: AI-based diagnostics; predictive disease modeling; intelligent monitoring systems; wearable and implantable devices; real-time therapeutic feedback; predictive modeling

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Treatment of Neurological Diseases

edited by

Theodora Afrantou

Panagiotis Ioannidis

and

Katerina D. Tzimourta

submission deadline 20 Jul 2026 | 2 articles | Viewed by 6788 | Submission Open

Keywords: neurological diseases; neurodegenerative diseases; Alzheimer’ s disease; Parkinson’ s disease; neurodegeneration; dementia; epilepsy

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Orthopedic Diseases: Surgical Treatments and Personalized Rehabilitation Strategies

edited by Eyal Yaacobi

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1538 | Submission Open

Keywords: orthopedic treatment; surgical technics; limb salvage; rehabilitation

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Advancing Anesthesia and Pain Control Through Precision Medicine

edited by

Francesco Vetrone

and

Angelo M. Pezzi

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1325 | Submission Open

Keywords: anesthesia; pain control; clinical practice; innovative techniques; evidence-based practice; pharmacology; personalized medicine; perioperative analgesia; chronic pain; acute pain

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Orthopedic Diseases: Advances in Limb Reconstruction

edited by Taylor J. Reif and Jason Shih Hoellwarth

submission deadline 20 Jul 2026 | 2 articles | Viewed by 1270 | Submission Open

Keywords: limb lengthening; limb deformity; malunion; nonunion; limb salvage; amputation reconstruction; osseointegration; osteomyelitis; patient-specific surgery; patient-specific instrumentation

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Pathogenesis and Personalized Management of Asthma

edited by

Mohammed Aref Kyyaly

and S. Hasan Arshad

submission deadline 20 Jul 2026 | Viewed by 158 | Submission Open

Keywords: asthma; pathogenesis; biomarkers; personalized medicine; precision therapy; severe asthma; immunopathology; molecular diagnostics

(This special issue belongs to the Section Mechanisms of Diseases)

Recent Advances in Prenatal Diagnosis and Fetal Therapy

edited by Gabrielle Tonni

submission deadline 20 Jul 2026 | Viewed by 145 | Submission Open

Keywords: prenatal diagnosis; fetal therapy; noninvasive prenatal testing (NIPT); next-generation sequencing (NGS); 3D rendering; personalized medicine; minimally invasive surgery; patient-centered care

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Approaches in Neurosurgery

edited by Alessandro Boaro and Marco Mammi

submission deadline 25 Jul 2026 | 2 articles | Viewed by 5746 | Submission Open

Keywords: neurosurgery; neuronavigation; neuro-imaging; clinical outcomes; machine learning

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Inborn Errors of Metabolism: From Pathomechanisms to Treatment

edited by

Andrés Felipe Leal

and

Carlos J. Almeciga-Diaz

submission deadline 25 Jul 2026 | 1 articles | Viewed by 2167 | Submission Open

Keywords: inherited metabolic disorders; pathway signaling; organelle interactions; immunomodulators; antioxidants; gene therapy

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Medicine in Pathological Diagnosis

edited by

Gianpietro Volonnino

and

Aniello Maiese

submission deadline 25 Jul 2026 | 1 articles | Viewed by 1053 | Submission Open

Keywords: personalized medicine; pathology; pathological; trauma; toxicology; informed consent

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Personalized Diagnosis and Management of Stroke

edited by Rubens José Gagliardi

submission deadline 25 Jul 2026 | 1 articles | Viewed by 700 | Submission Open

Keywords: stroke; cerebrovascular disease; carotid disease; epidemiology

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Neuroimaging Biomarkers for Precision Medicine in Neuropsychiatry: A Multidisciplinary Update

edited by

Daniel Martins

submission deadline 25 Jul 2026 | Viewed by 332 | Submission Open

Keywords: neuroimaging; neuropsychiatry; psychiatry; psychology; neuroscience; biomarkers; precision medicine

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Radiomics: Unlocking Personalized Insights from Medical Images

edited by

Genti Xhepa

Baptiste Bonnet

and

Alexis Ricoeur

submission deadline 25 Jul 2026 | Viewed by 106 | Submission Open

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Molecular Pathology of Digestive Oncology

edited by

Takashi Murakami

submission deadline 25 Jul 2026 | Viewed by 62 | Submission Open

Keywords: molecular biomarkers; genetic and epigenetic alterations; tumor microenvironment; gut microbiome; carcinogenesis; early detection

(This special issue belongs to the Section Molecular Targeted Therapy)

Novel Challenges and Advances in Orthopaedic and Trauma Surgery

edited by

Dimitrios Kitridis

and

Panagiotis Givissis

submission deadline 30 Jul 2026 | 4 articles | Viewed by 13347 | Submission Open

Keywords: orthopaedic surgery; traumatology; musculoskeletal disorders; innovation in orthopaedics; individualised treatment; post-operative rehabilitation; clinical research

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Cardiothoracic Surgery: Challenges and Future Perspectives

edited by Thomas Theologou

submission deadline 30 Jul 2026 | Viewed by 86 | Submission Open

Keywords: cardiothoracic surgery; minimally invasive surgery; robotic surgery; heart transplantation; lung transplantation; thoracic oncology; perioperative care; artificial intelligence in surgery; surgical innovation; postoperative complications; personalized medicine

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Medicine in Orthopaedics, 2nd Edition

edited by

Arne Kienzle

and

Henrik Bäcker

submission deadline 31 Jul 2026 | 7 articles | Viewed by 16235 | Submission Open

Keywords: outcomes; orthopedic surgery; traumatology; radiography; complication

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Personalized Treatment for Heart Failure

edited by Shunsuke Kiuchi

submission deadline 31 Jul 2026 | 4 articles | Viewed by 6184 | Submission Open

Keywords: hypertension; heart failure; prevention; left ventricular contractility; cardiovascular outcomes; cardiology

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

New Advances in Techniques and Personalized Medicine in Cardiology

edited by

Camilla Calvieri

submission deadline 31 Jul 2026 | 1 articles | Viewed by 5466 | Submission Open

Keywords: cardiovascular precision therapy; cardiovascular pharmacological therapy; pharmacogenetics; cardio-imaging; epigenetics; personalized medicine

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Precision Tumor Therapy: The Role of PARP Inhibitors in Personalized Medicine

edited by Christos Emmanouilides

submission deadline 31 Jul 2026 | Viewed by 1120 | Submission Open

Keywords: cancer therapy; PARP inhibitors; gynecologic cancers; PARP inhabitor trials; personalized medicine

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Personalized Medicine in Metabolism Disorders

edited by Mehrnaz Abbasi

submission deadline 31 Jul 2026 | Viewed by 229 | Submission Open

Keywords: metabolic syndrome; obesity; insulin resistance; hypertension; type 2 diabetes; energy metabolism; fatty acid oxida-tion; gut microbiota; brown adipose tissue (BAT); white adipose tissue (WAT); nutritional interventions; lifestyle modifications; pharmacological treatments; phytochemicals; vitamins and supplements; public health; epidemiology of obesity; preventive strategies; genetic factors; metabolic health research; adipose tissue function

(This special issue belongs to the Section Mechanisms of Diseases)

Clinical Progress of Diabetic Foot

edited by

Piergiorgio Francia

Roberto Anichini

Leonardo Bocchi

and Alessandra De Bellis

submission deadline 31 Jul 2026 | Viewed by 122 | Submission Open

Keywords: diabetic foot; personalized medicine; advanced therapies; clinical management; biomarkers; diabetes complications; risk assessment; preventive care; artificial intelligence; data science

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Medicine in Kidney Transplantation

edited by Jon Von Visger

submission deadline 31 Jul 2026 | Viewed by 110 | Submission Open

Keywords: kidney transplantation personalized medicine renal disease nephrology graft survival immunosuppressive therapy recurrent disease patient survival access to transplant

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

New Advances and Personalized Treatment in Otolaryngology

edited by Gabriella Cadoni

submission deadline 31 Jul 2026 | Viewed by 74 | Submission Open

Keywords: otorhinolaryngology; head and neck cancer; otology; rhinology; epidemiology; artificial intelligence; genic therapy; robotic surgery; endoscopic surgery; single cell

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Advances in Ischemic Stroke Management: Toward Precision Medicine

edited by Bruno Kusznir Vitturi

submission deadline 31 Jul 2026 | Viewed by 32 | Submission Open

Keywords: cerebrovascular diseases; ischemic stroke; brain hemorrhage; secondary prevention; thrombolysis; endovascular treatment

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Personalized Gastric Cancer Treatment: Recent Progress and Future Perspectives

edited by Gagandeep Brar

submission deadline 10 Aug 2026 | Viewed by 69 | Submission Open

Keywords: gastric cancer; biomarkers; targeted therapy; personalized medicine

(This special issue belongs to the Section Precision Oncology)

Recent Innovations and Artificial Intelligence in Interventional Radiology: A Step Towards Personalized Medicine

edited by

Maurizio Cè

, Giuseppe Pellegrino and Salvatore Alessio Angileri

submission deadline 15 Aug 2026 | 3 articles | Viewed by 2137 | Submission Open

Keywords: interventional radiology; artificial intelligence; augmented reality

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Ehealth, Telemedicine, and AI in the Precision Medicine Era

edited by

Mirella Veras

submission deadline 20 Aug 2026 | 4 articles | Viewed by 22247 | Submission Open

Keywords: digital health; artificial intelligence; telemedicine; telerehabilitation; E-health; precision medicine; remote monitoring; wearable devices; mobile health (mHealth); virtual health; health informatics; machine learning; predictive analytics; personalized medicine; health technology

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Clinical Research of Minimally Invasive Spine Surgery

edited by

Paulo Pereira

and Bertrand Debono

submission deadline 20 Aug 2026 | 2 articles | Viewed by 4018 | Submission Open

Keywords: minimally invasive spine surgery; MISS; surgical techniques; patient outcomes; clinical research; technological advancements; robotics; navigation systems; patient safety; quality of life

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Therapeutic Strategies in Gastrointestinal Surgery

edited by Francesco Santullo

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1508 | Submission Open

Keywords: surgical oncology; cytoreductive surgery; laparoscopic surgery; colorectal surgery; gastric cancer; hipec; pipac; peritoneal metastases

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Mechanisms of Airway Inflammation in Asthma

edited by Kathleen Haley

submission deadline 20 Aug 2026 | Viewed by 539 | Submission Open

Keywords: asthma; inflammation in asthma; targeted therapies; acute respiratory distress syndrome; chronic lung diseases; critical care

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

State of the Art in Cardiac Imaging

edited by

Katarzyna Holcman

submission deadline 25 Aug 2026 | 2 articles | Viewed by 4057 | Submission Open

Keywords: cardiology; imaging; scintigraphy; SPECT; PET; computed tomography; magnetic resonance; echocardiography; heart failure; coronary artery disease

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Interventional Cardiology: Latest Technology, Progress and Challenge

edited by Grzegorz Sobieszek and Maksymilian P. Opolski

submission deadline 25 Aug 2026 | 2 articles | Viewed by 3528 | Submission Open

Keywords: interventional cardiology; chronic total occlusions (CTO); complex and high-risk coronary interventions (CHIP); intravascular lithotripsy (IVL); structural heart interventions; heart failure interventional treatment; electrotherapy; right- and left-ventricle hemodynamic support; left-ventricle assist device (LVAD)

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Precision Pathology: Bridging Digital Innovation and Molecular Diagnostics

edited by

Albino Eccher

and Stefano Marletta

submission deadline 25 Aug 2026 | 1 articles | Viewed by 576 | Submission Open

Keywords: precision pathology; digital pathology; molecular diagnostics; artificial intelligence in pathology; computational pathology; multi-omics integration; biomarker discovery; translational medicine

(This special issue belongs to the Section Omics/Informatics)

Gestational Diabetes: Challenges and Cutting-Edge Research

edited by

Athanasios N. Tsartsalis

and

George I. Lambrou

submission deadline 25 Aug 2026 | Viewed by 228 | Submission Open

Keywords: gestational diabetes; continuous glucose monitor; fetal health; pregnancy; macrosomia; personalized management

(This special issue belongs to the Section Mechanisms of Diseases)

Personalized Management of Heart Failure: From Biomarkers to Clinical Practice

edited by

Andre Rodrigues Durães

submission deadline 25 Aug 2026 | 1 articles | Viewed by 150 | Submission Open

Keywords: heart failure (HF); cardiac biomarkers; guideline-directed medical therapy (GDMT); risk stratification; HF phenotypes; HF management; digital health

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Medicine in Pediatric Surgery: Updates and Perspectives

edited by

George Vaos

and

Nikolaos Zavras

submission deadline 25 Aug 2026 | Viewed by 61 | Submission Open

Keywords: personalized medicine; pediatric surgery; genomics; surgical oncology; inflammatory bowel disease; obesity; metabolic surgery; Hirschsprung's disease; artificial intelligence; machine learning

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Advancing Tailored Diagnostics and Therapeutics in Autoimmune and Rheumatic Diseases via Integration of Traditional Approaches and AI Technologies

edited by Edda Russo and Francesca Romano

submission deadline 25 Aug 2026 | Viewed by 55 | Submission Open

Keywords: autoimmune diseases; personalized therapeutics; biomarker profiling; artificial intelligence (AI); targeted immunotherapy

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Medicine in Anesthesia and Intensive Care

edited by Marc Olivier Fischer

submission deadline 27 Aug 2026 | Viewed by 96 | Submission Open

Keywords: anaesthesia; critical care; personalized medicine; preoperative risk stratification; close loop anaesthesia; mechanical ventilation; individualized sedation; postoperative outcome; postoperative trajectories

(This special issue belongs to the Section Personalized Medical Care)

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