New Insight into Aging and Geriatric Syndromes: Clinical Updates and Perspectives

Dear Colleagues,

The average lifespan of people is rising. A recent WHO report estimates that by 2050, the global population of people aged 60 years and older will double, while the number of people aged 80 years and older is expected to triple between 2020 and 2050. Consequently, there is an increasing priority to deal with age-related diseases, with the goal of ensuring the autonomy of older persons and social integration.

Physicians, researchers, and the public health community must develop a culture of sensitivity to the needs of this population and its subgroups.

In 1965, Bernard Isaacs coined the term “geriatric giants”, including in this definition syndromes such as immobility, instability and falls, incontinence (urinary and fecal), and intellectual impairment (delirium and dementia). Over the subsequent five decades, the modern “geriatric giants” have evolved, encompassing the four new syndromes of frailty, sarcopenia, the anorexia of aging, and cognitive impairment. Therefore, in the last decade, there has been increasing awareness of different geriatric syndromes, such as frailty, urinary incontinence, falls, delirium, sarcopenia, age-related hearing loss, polypharmacy, and pressure ulcers, that are highly prevalent, have multifactorial pathogenesis, and are often associated with substantial multimorbidity and poor health-related outcomes. With the rapid increase in the aging population over the first half of this century and a paucity of geriatricians worldwide, there is a major need to enhance the ability of primary care physicians and advance practice nurses to recognize and manage geriatric syndromes using comprehensive geriatric assessment (CGA) and related evaluation tools.

Dr. Vittorio Dibello
Dr. Francesco Panza
Prof. Dr. Vincenzo Solfrizzi
Guest Editors

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