Personalized Medicine in Pediatric Surgery: Updates and Perspectives

Dear Colleagues,

Traditionally, the management of pediatric surgical patients relies on standardized protocols based on congenital anomalies, disease stage, age of the patients, epidemiology, and evidence of care. However, this approach often overlooks the heterogeneity presented in the pediatric population that has unique molecular and developmental characteristics. The emergence of personalized medicine, fueled by advantages in genomics, proteomics, and bioinformatics, is poised to revolutionize pediatric surgical care. Personalized medicine in pediatric surgery tailors therapy to each child’s genetic make-up, developmental stage, and environmental factor to optimize outcomes and minimize complications.

This Special Issue, “Personalized Medicine in Pediatric Surgery: Updates and Perspectives”, aims to provide an update on the challenges that arise, as personalized medicine is practiced more widely in pediatric surgery, and to discuss future perspectives for advancing the principles of personalized medicine in pediatric surgical patients.

Topics of interest include, but are not confined to, the following:

• Tailored preventive, diagnostic and therapeutic regimens in pediatric surgery.
• Genomic research related to pediatric surgical diseases (benign or malignant) and their therapeutic response.
• Genetic variability, developmental stage, and exposure to environmental factors in optimizing outcomes for pediatric surgical patients.
• Challenges in personalized medicine in pediatric surgery.
• Personalized metabolic surgery in adolescents.
• Informatics applied to personalized medicine in pediatric surgery, including artificial intelligence and machine learning.

Original prospective and retrospective research articles, as well as systematic reviews, meta-analyses and narrative  

reviews are welcome. Relevant basic, translational, and clinical research is also encouraged.

Prof. Dr. George Vaos
Dr. Nikolaos Zavras
Guest Editors

Manuscript Submission Information

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