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Orthopedic Diseases: Surgical Treatments and Personalized Rehabilitation Strategies
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Orthopedic Diseases: Surgical Treatments and Personalized Rehabilitation Strategies

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 170

Special Issue Editor

Dr. Eyal Yaacobi

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Guest Editor
Department of Orthopedic Surgery, Meir Medical Center, Tel-Aviv University, Kfar-Saba 4428164, Israel
Interests: orthopaedics; trauma; limb salvage; orthopedic surgery

Special Issue Information

Dear Colleagues,

Orthopedic diseases encompass a wide range of conditions affecting bones, joints, muscles, ligaments, and tendons. From acute injuries to chronic bone and joint conditions, advances in surgical treatments and rehabilitation strategies have significantly improved outcomes for patients suffering from these conditions. Emerging technologies, such as robotic-assisted surgeries and 3D-printed implants, are enhancing precision and customization in treatment with the main aim of addressing the time taken to return to an active lifestyle.

Rehabilitation plays a crucial role in recovery, aiming to restore function, strengthen the affected areas, and prevent further injury. Tailored physical therapy programs incorporate exercises to improve mobility, flexibility, and strength. Adjunct therapies like occupational therapy, hydrotherapy, and the use of assistive devices further support rehabilitation. Innovations in rehabilitation include virtual-reality-based therapy and biofeedback systems, which offer interactive and personalized approaches.

The integration of surgical advancements with comprehensive rehabilitation ensures better long-term outcomes, helping patients regain independence and improve their quality of life. The collaborative efforts of orthopedic surgeons, physiotherapists, and other specialists remain pivotal in managing these conditions effectively.

This Special Issue is dedicated to all clinicians and researchers involved in the care and management of orthopedic diseases. It aims to present the current state of the art in surgical treatments and rehabilitation strategies, while exploring potential future therapeutic and research avenues to support healthcare professionals. Its focus spans various disciplines, including orthopedic surgery, physical therapy, sports medicine, and rehabilitation sciences, as well as general medicine.

Dr. Eyal Yaacobi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • orthopedic treatment
  • surgical technics
  • limb salvage
  • rehabilitation

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Published Papers (1 paper)

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Research

14 pages, 1301 KiB  
Article
Guarded Outcomes After Hip Hemiarthroplasty in Patients with Cerebral Palsy: Highlighting a Personalized Medicine Approach to Mitigate the Risk of Complications
by Ahmed Nageeb Mahmoud, Nicholas R. Brule, Juan D. Bernate, Mark A. Seeley, Michael Suk and Daniel S. Horwitz
J. Pers. Med. 2025, 15(6), 252; https://doi.org/10.3390/jpm15060252 - 15 Jun 2025
Abstract
Background: The effectiveness of hip hemiarthroplasty in managing femoral neck fractures in individuals with cerebral palsy has seldom been reported. Objectives: Given the complex neuromuscular issues associated with cerebral palsy (CP), this retrospective study aims to document the outcomes and characterize the complications [...] Read more.
Background: The effectiveness of hip hemiarthroplasty in managing femoral neck fractures in individuals with cerebral palsy has seldom been reported. Objectives: Given the complex neuromuscular issues associated with cerebral palsy (CP), this retrospective study aims to document the outcomes and characterize the complications of hip hemiarthroplasty for fractures of the femoral neck in a series of patients with CP, emphasizing the role of precision medicine in management. Methods: Six cases of hip hemiarthroplasty in six male patients with cerebral palsy and displaced femoral neck fractures have been reviewed in this study. The patients’ mean age at the time of surgery was 55.6 ± 14.1 years (range, 33–71). All the patients were independent indoor ambulators before their femoral neck fracture and had various medical comorbidities. Five patients had intellectual disabilities. Results: The mean clinical and radiographic follow-ups for the patients included in this series were 91.5 and 71.3 months, respectively. All the patients developed significant heterotopic ossification (HO) around the operated hip, which was observed as early as the second week postoperatively on radiographs. HO progressed throughout the follow-up for all the patients. One patient had an early postoperative dislocation with femoral stem loosening, which was managed by implant revision. Another patient had an acetabular protrusion, leading to the loss of their weight-bearing ability and mobility due to pain. Four patients were deceased at a mean of 86.5 months after the index surgery. Conclusions: After considering the preliminary evidence provided with this small case series, this study suggests the overall guarded outcomes of hip hemiarthroplasty in patients with CP. Given the 100% rate of heterotopic ossification, a precision medicine framework with consideration for HO prophylaxis may be recommended after hip hemiarthroplasty in patients with CP. It may also be reasonable to scrutinize a personalized risk assessment approach in this patient subset regarding decision making, surgical approach, and rehabilitation program. The clinical outcomes and the risks of complications following hemiarthroplasty should be sensibly presented to patients with cerebral palsy and their caregivers to achieve reasonable postoperative expectations. Full article
(This article belongs to the Special Issue Orthopedic Diseases: Surgical Treatments and Personalized Rehabilitation Strategies)
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