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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Intracranial Aneurysms: What Do We Know So Far?

edited by Alessio Albanese and Giuseppe Esposito

submission deadline 20 Mar 2026 | Viewed by 12 | Submission Open

Keywords: intracranial aneurysms; clipping; endovascular therapy; stenting; coiling; cerebral vasospasm; cerebrovascular diseases; microneurosurgery; subarachnoid hemorrhage; bypass

(This special issue belongs to the Section Clinical Neurology)

Advances and Challenges in Colorectal Cancer

edited by Vignesh Narasimhan

submission deadline 20 Mar 2026 | Viewed by 11 | Submission Open

Keywords: anal fistula; advancement flap; ‎ ligation of intersphincteric tract; haemorrhoid surgery; pilonidal surgery

(This special issue belongs to the Section Oncology)

Current Paradigms in Pulmonary Vascular Disease: Past, Present and Future

edited by Parth M. Rali

submission deadline 20 Mar 2026 | Viewed by 7 | Submission Open

Keywords: pulmonary hypertension (PH); pulmonary embolism (PE); rare pulmonary vascular disorders; novel therapeutics; di-agnostic innovations

(This special issue belongs to the Section Respiratory Medicine)

Advances in Clinical Exercise for Health

edited by

Pedro Miguel Forte

and Joana Ribeiro

submission deadline 20 Mar 2026 | Viewed by 6 | Submission Open

Keywords: clinical exercise science; physical activity; chronic disease prevention; biomechanics; healthy aging; physiology

(This special issue belongs to the Section Sports Medicine)

Rectal Cancer: Screening, Treatment and Prevention

edited by Fernando Mendoza-Moreno

submission deadline 20 Mar 2026 | Viewed by 4 | Submission Open

Keywords: rectal cancer; cancer screening; neoadjuvant therapy; minimally invasive surgery; oncologic outcomes; multidiscipli-nary care; health disparities

(This special issue belongs to the Section Oncology)

Pediatric Otolaryngology: Clinical Advances and Challenges

edited by

Manabu Komori

and

Masaomi Motegi

submission deadline 20 Mar 2026 | Viewed by 3 | Submission Open

Keywords: pediatric dizziness; laryngomalacia; subglottic stenosis; pediatric airway obstruction; intracapsular tonsillectomy; PITA (Powered Intracapsular Tonsillectomy and Adenoidectomy); pediatric sleep-disordered breathing; pediatric olfactory disorders; congenital anosmia

(This special issue belongs to the Section Clinical Pediatrics)

Exercise and Chronic Pain

edited by Nuria Marín-Jiménez and Milkana Borges-Cosic

submission deadline 20 Mar 2026 | Viewed by 1 | Submission Open

Keywords: chronic pain; exercise therapy; physical activity; fitness; pain management; quality of life; non-pharmacological interventions

(This special issue belongs to the Section Sports Medicine)

Personalized Medicine and Treatment in Inflammatory Bowel Diseases

edited by Carmen Monica Preda and

Cristian George Tieranu

submission deadline 21 Mar 2026 | Viewed by 40 | Submission Open

Keywords: personalized medicine; inflammatory bowel diseases (IBDs); Crohn’ s disease; ulcerative colitis; biomarkers; pharmacogenomics; microbiome; anti-TNF therapy; precision medicine; machine learning

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

New Technologies and Translational Approach for an Early Diagnosis of Bipolar Spectrum and Hyperactive and Novelty Seeking Profiles

edited by

Massimo Tusconi

, Serdar Dursun and

Germano Orru

submission deadline 25 Mar 2026 | 4 articles | Viewed by 5270 | Submission Open

Keywords: psychiatry; mental health; bipolar disorders; mood; biomarkers; new technology; BD

(This special issue belongs to the Section Mental Health)

Clinical Innovations in Laboratory Medicine to Advance Diagnostic and Improve Patient Outcomes

edited by

Jing Cao

and

Xin Yi

submission deadline 25 Mar 2026 | 1 articles | Viewed by 290 | Submission Open

Keywords: health equity; laboratory diagnostics; near-patient testing; diagnostic access; underserved patient populations; disparities in healthcare; patient outcome

(This special issue belongs to the Section Clinical Laboratory Medicine)

Translational Immunology in Clinical Medicine: From Preclinical Insights to Therapeutic Impact

edited by

Soheil Tavakolpour

submission deadline 25 Mar 2026 | Viewed by 53 | Submission Open

Keywords: translational immunology; autoimmune disease; autoinflammatory disease; immune-mediated diseases; oncology; preclinical models; immune efficacy and safety; mechanism of action; immunotoxicity assessment

(This special issue belongs to the Section Immunology)

Osteosarcoma: New Insights into Diagnosis and Treatment

edited by Lars M. Wagner

submission deadline 25 Mar 2026 | Viewed by 46 | Submission Open

Keywords: osteosarcoma; tyrosine kinase inhibitors; immunotherapy; clinical trial design; intratumoral heterogeneity; liquid biopsy; metastasectomy; deep learning; translational research; targeted therapy

(This special issue belongs to the Section Oncology)

From Hyperfunction to Insufficiency: A Comprehensive Look at Adrenal Disorders

edited by

Jorge Gabriel Ruiz-Sánchez

and Patricia Y. Fechner

submission deadline 25 Mar 2026 | Viewed by 39 | Submission Open

Keywords: primary aldosteronism; hypoaldosteronism; hypercortisolism; adrenal insufficiency; autonomous cortisol secretion; cushing syndrome

(This special issue belongs to the Section Endocrinology & Metabolism)

Acute Care for Traumatic Injuries and Surgical Outcomes: 2nd Edition

edited by Matthias Fröhlich and Michael Caspers

submission deadline 25 Mar 2026 | Viewed by 37 | Submission Open

Keywords: trauma injuries; orthopedics; polytrauma; emergency care; coagulation disorders; fractures; surgical outcomes; acute care; diagnostic imaging

(This special issue belongs to the Section Emergency Medicine)

Corneal Surgery: From Innovation to Clinical Practice

edited by Joanna Wasielica-Poslednik

submission deadline 25 Mar 2026 | Viewed by 28 | Submission Open

Keywords: keratoplasty; penetrating keratoplasty; DMEK; eye banking; corneal surgery

(This special issue belongs to the Section Ophthalmology)

Contemporary Trends in Cardiovascular Prevention

edited by Alessandro Durante and

Alessandro Mazzapicchi

submission deadline 25 Mar 2026 | Viewed by 27 | Submission Open

Keywords: interventional cardiology; coronary artery disease; carotid artery disease; aortic valve disease; left atrial appendage closure; hypercholesterolemia

(This special issue belongs to the Section Cardiovascular Medicine)

Advances in Schizophrenia and Related Psychotic Disorders

edited by Giovanni Camardese and Michele Ribolsi

submission deadline 25 Mar 2026 | Viewed by 21 | Submission Open

Keywords: psychosis; schizophrenia; severe mental illness; psychopharmacology; negative symptoms; antipsychotics

(This special issue belongs to the Section Mental Health)

Breast MRI: An Update

edited by

Filippo Pesapane

and

Anna Rotili

submission deadline 25 Mar 2026 | Viewed by 20 | Submission Open

Keywords: breast cancer; breast imaging; magnetic resonance imaging; diffusion-weighted imaging; contrast-enhanced sequences; artificial intelligence

(This special issue belongs to the Section Obstetrics & Gynecology)

Meibomian Gland Dysfunction and Dry Eye Diseases

edited by

Reiko Arita

and

KyoungYul Seo

submission deadline 25 Mar 2026 | Viewed by 18 | Submission Open

Keywords: meibomian gland; meibomian gland dysfunction; dry eye disease; ocular surface; meibography; lipid layer; tear film; inflammation; therapy; diagnosis; epidemiology; clinical study

(This special issue belongs to the Section Ophthalmology)

Diagnosis and Treatment for Hearing Loss: Expert Views

edited by

Robert A. Saadi

and John L. Dornhoffer

submission deadline 25 Mar 2026 | Viewed by 17 | Submission Open

Keywords: hearing loss; cochlear implants; hearing aid technology; regenerative medicine; diagnostic audiology

(This special issue belongs to the Section Otolaryngology)

Endocarditis: Clinical Updates on Diagnosis, Treatment and Management

edited by Katarzyna Holcman

submission deadline 25 Mar 2026 | Viewed by 16 | Submission Open

Keywords: infective endocarditis; PET; SPECT; echocardiography; antimicrobial therapy; cardiac surgery; multimodality imaging

(This special issue belongs to the Section Cardiology)

"Visceral Aneurysm" in 2025: Recent Advances and Treatment (Second Edition)

edited by Enrico Maria Marone

submission deadline 25 Mar 2026 | Viewed by 15 | Submission Open

Keywords: visceral aneurysms; vascular surgery; endovascular treatment; lparoscopic surgery; robotic surgery; embolization; flow-diverting stents; covered stents

(This special issue belongs to the Section Vascular Medicine)

Hematologic Malignancies: Treatment Strategies and Future Challenges: 2nd Edition

edited by Masaaki Noguchi

submission deadline 25 Mar 2026 | Viewed by 14 | Submission Open

Keywords: hematologic malignancies; relapse; refractory; drug resistance; therapeutic strategies; new target; biomarkers; new insights

(This special issue belongs to the Section Hematology)

From Heart to Brain: Interdisciplinary Perspectives on Cerebral Infarction

edited by

Laurent Suissa

and Jean-Claude Deharo

submission deadline 25 Mar 2026 | Viewed by 14 | Submission Open

Keywords: ischemic stroke; cardioembolic stroke; atrial fibrillation; heart– brain axis; neurocardiology; post-stroke cardiac dysfunction; stroke prevention; cerebral infarction; cardiac monitoring in stroke; secondary stroke prevention

(This special issue belongs to the Section Clinical Neurology)

Pulmonary Embolism: Bridging Cutting-Edge Research and Clinical Practice

edited by

Bedros Taslakian

and Vivian Lee Bishay

submission deadline 25 Mar 2026 | Viewed by 11 | Submission Open

Keywords: pulmonary embolism; catheter-directed thrombectomy; catheter-directed thrombolysis; post-pulmonary embolism syndrome; chronic thromboembolic disease; chronic thromboembolic pulmonary hypertension

(This special issue belongs to the Section Respiratory Medicine)

Artificial Intelligence in Acute Care Surgery and Trauma Health Care

edited by

Sergio M. Navarro

and Daniel Stephens

submission deadline 25 Mar 2026 | Viewed by 10 | Submission Open

Keywords: artificial neural networks; robotic surgery; virtual reality; augmented reality; artificial intelligence; virtual reality; deep learning

(This special issue belongs to the Section Emergency Medicine)

Degenerative Cervical Myelopathy and Traumatic Spinal Cord Injury: Recent Advances and Future Directions

edited by Nader Hejrati,

Michael G. Fehlings

and Maryam Seif

submission deadline 28 Mar 2026 | 1 articles | Viewed by 584 | Submission Open

Keywords: degenerative cervical myelopathy; traumatic spinal cord injury; clinical assessment; surgical management; non-operative management; neuroprotective therapies; neuroregenerative therapies; outcome prediction

(This special issue belongs to the Section Clinical Neurology)

Clinical Novel Research in the Management of Cardiac Arrest

edited by Giovanni Babini and

Alberto Cucino

submission deadline 28 Mar 2026 | Viewed by 487 | Submission Open

Keywords: cardiac arrest; post-cardiac arrest syndrome; resuscitation; temperature control; target temperature management; neuroprotection; neuroprognostication; defibrillation; extracorporeal life support

(This special issue belongs to the Section Cardiology)

Clinical Management of Cholecystitis and Complications

edited by Dimitrios Balalis,

Dimitrios K. Manatakis

and Nikolaos Vassos

submission deadline 28 Mar 2026 | Viewed by 41 | Submission Open

Keywords: gallbladder; cholecystitis; right upper quadrant pain; ultrasound; laparoscopic approach

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Mitral Valve Stenosis or Aortic Valve Stenosis: Progress from Diagnosis to Treatment

edited by Francesco Melillo

submission deadline 28 Mar 2026 | Viewed by 39 | Submission Open

Keywords: aortic stenosis; mitral stenosis; TAVI

(This special issue belongs to the Section Cardiology)

Management of Female Pelvic Floor Disorders and Incontinence

edited by Luis López Fando

submission deadline 28 Mar 2026 | Viewed by 30 | Submission Open

Keywords: pelvic floor disorders; urinary incontinence; pelvic organ prolapse; reconstructive urology; voiding dysfunction; multidisciplinary care; surgical techniques; urodynamics; patient-centered outcomes; digital learning in urology

(This special issue belongs to the Section Nephrology & Urology)

JSOPB 2025–2026 Congress Special Issue–Update on Organ Preservation and Transplantation

edited by

Issei Saitoh

and

Takashi Kenmochi

submission deadline 31 Mar 2026 | Viewed by 121 | Submission Open

Keywords: organ preservation; transplantation; pharmacology; engineering; stem cell therapy

(This special issue belongs to the Section General Surgery)

New Insights into Clinical Application of Embolization Techniques

edited by

Bedros Taslakian

and Yan Epelboym

submission deadline 31 Mar 2026 | Viewed by 81 | Submission Open

Keywords: embolization; interventional radiology; musculoskeletal embolization; uterine artery embolization; prostate artery embolization; vascular malformations; catheter-directed therapy

(This special issue belongs to the Section Vascular Medicine)

Cardiovascular Autonomic Function: From Bench to Bedside—2nd Edition

edited by

Vera Geraldes

and

Isabel Rocha

submission deadline 31 Mar 2026 | Viewed by 79 | Submission Open

Keywords: dysautonomia; heart rate variability; autonomic function testing; cardiovascular autonomic function; autonomic neuroscience; syncope; orthostatic hypotension; baroreflex; autonomic molecular mechanisms

(This special issue belongs to the Section Cardiology)

Artificial Intelligence in Women’s Health and Medicine: Improving Clinical Practice, Diagnosis, Treatment Management and Patient Experiences

edited by

Shivaram Poigai Arunachalam

and Nasibeh Zanjirani Farahani

submission deadline 31 Mar 2026 | Viewed by 57 | Submission Open

Keywords: women’ s health; artificial intelligence; machine learning; personalized medicine; reproductive health; health equity; social determinants of health; mental health; cancer; cardiovascular disease

(This special issue belongs to the Section Epidemiology & Public Health)

Thoracic Radiochemoimmunotherapy for Non-Small Cell Lung Cancer (NSCLC): Evolving Techniques and Clinical Applications

edited by

Franz Zehentmayr

submission deadline 31 Mar 2026 | Viewed by 43 | Submission Open

Keywords: radiotherapy; radiology; oncology; non-small cell lung cancer; real-world data; immunotherapy; radiation dose escalation

(This special issue belongs to the Section Oncology)

Acute Trauma and Trauma Care in Orthopedics: 2nd Edition

edited by

Pietro Maniscalco

and

Gianfilippo Caggiari

submission deadline 31 Mar 2026 | Viewed by 43 | Submission Open

Keywords: orthopedics; trauma; injury; musculoskeletal; surgery; knee; osteoarthritis; spinal deformity; fracture; joint replacement; hip fractur; fragility fracture; minimally invasive surgery; post-traumatic care and rehabilitation; pain management; emergency assessment

(This special issue belongs to the Section Orthopedics)

Latest Advances in Glaucoma, Cataracts, and Refractive Surgery

edited by

Adrian Gericke

, Felix Wagner and

Julia Verena Stingl

submission deadline 31 Mar 2026 | Viewed by 32 | Submission Open

Keywords: glaucoma; cataract surgery; refractive surgery; minimally invasive glaucoma surgery (MIGS); laser vision correc-tion (LVC); keratorefractive lenticule extraction (KLEx); lenticule implantation; multifocal IOLs; extended depth-of-focus (EDOF) lenses; ocular imaging; optical coherence tomography (OCT); artificial intelligence in ophthalmology; corneal biomechanics; surgical innovation

(This special issue belongs to the Section Ophthalmology)

Pregnancy and Delivery Complications: Bridging Research and Clinical Practice

edited by

Maria Patricia Roman

, Andrei Mihai Malutan and Răzvan Ciortea

submission deadline 31 Mar 2026 | Viewed by 30 | Submission Open

Keywords: maternal– fetal medicine; obstetric complications; perinatal health; pelvic floor disorders; childbirth perineal trauma; risk stratification; patient-reported outcomes; patient-reported outcome measures

(This special issue belongs to the Section Obstetrics & Gynecology)

Endodontic Diseases: Prevalence, Risk Factors, and Treatment Outcomes

edited by Iris Slutzky-Goldberg, Shlomo Matalon and

Hagay Slutzky

submission deadline 31 Mar 2026 | Viewed by 22 | Submission Open

Keywords: cone beam computed tomography (cbct); diagnostic tools; endodontic therapy; peri-radicular pathologies; regenerative endodontics; risk factors; systemic disease; treatment outcome; vital pulp therapy

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Recent Clinical Perspective in Kidney Transplantation

edited by Nikolina Bašić-Jukić

submission deadline 31 Mar 2026 | Viewed by 22 | Submission Open

Keywords: kidney transplantation; outcomes; desensitization; xenotransplantation; transplant nephropathology; multiorgan transplantations; post-transplant complications; inequities in transplantation

(This special issue belongs to the Section Nephrology & Urology)

Clinical Advances in Laser Dentistry: Emerging Therapeutic Concepts

edited by

Satoshi Watanabe

and Risako Mikami

submission deadline 31 Mar 2026 | Viewed by 17 | Submission Open

Keywords: laser dentistry; dental treatment guidelines; refractory endodontic infection; root canal therapy; minimally invasive endodontics; anatomy; cone-beam computed tomography

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Current Emerging Treatment Options in Atrial Fibrillation

edited by Hoang Nhat Pham and Amitoj Singh

submission deadline 31 Mar 2026 | Viewed by 17 | Submission Open

Keywords: atrial fibrillation; AF ablation; lifestyle intervention; rhythm control; pulsed field ablation; antiarrhythmic drugs; direct oral anticoagulants

(This special issue belongs to the Section Cardiology)

Advances in Perioperative Care: Challenges and Perspectives in Enhanced Recovery After Surgery, Perioperative Optimization and Prehabilitation: 2nd Edition

edited by

Carlos Cerdán Santacruz

submission deadline 31 Mar 2026 | Viewed by 17 | Submission Open

Keywords: perioperative care; enhanced recovery after surgery; prehabilitation; minimally invasive surgery; patient-related outcome measures; colorectal surgery; general surgery; thoracic surgery; vascular surgery; optimal functional recovery

(This special issue belongs to the Section General Surgery)

Acute Myocardial Infarction: Diagnosis and Novel Treatment Opportunities

edited by

Danilo Menichelli

and Flavio Giuseppe Biccirè

submission deadline 31 Mar 2026 | Viewed by 16 | Submission Open

Keywords: acute myocardial infarction; atherosclerosis; percutaneous coronary intervention; atherothrombosis; inflammation; dyslipidemia; lipid-lowering therapy

(This special issue belongs to the Section Cardiology)

Advancements in Lumbar Spine Surgery: Modern Strategies and Techniques

edited by Christian von der Brelie and Frank Beyer

submission deadline 31 Mar 2026 | Viewed by 14 | Submission Open

Keywords: lumbar spine; spine surgery; new techniques; robotics; minimally-invasive; artificial intelligence (AI); navigation

(This special issue belongs to the Section Orthopedics)

Oral Biology: Advances of Translating Experimental Findings into Clinical Dentistry and Oral Medicine

edited by

Andrea Palermo

submission deadline 31 Mar 2026 | Viewed by 12 | Submission Open

Keywords: oral surgery; biomaterials; tissue engineering; regenerative medicine; dentistry dentin graft; growth factors; ad-vances orthodontics; skeletal anchorage with miniscrews; TADS; MADS; MARPE; aligner

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Glaucoma: Diagnosis and Management Insights

edited by

Stamatios Lampsas

and Eythimios Karmiris

submission deadline 31 Mar 2026 | Viewed by 11 | Submission Open

Keywords: glaucoma; risk factors; progression; novel biomarkers; diagnosis; management

(This special issue belongs to the Section Ophthalmology)

New Insights into Cardiovascular Radiology

edited by Amalia Lupi and Riccardo Cau

submission deadline 31 Mar 2026 | Viewed by 10 | Submission Open

Keywords: CMR; tissue characterization; 4Dflow; CCTA; photon counting CT; plaque characterization

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Acute Care Surgery: The Evolution of a Modern Specialty

edited by Mayur Narayan

submission deadline 31 Mar 2026 | Viewed by 8 | Submission Open

Keywords: acute care surgery; emergency surgery; health equity; global surgery; trauma care; surgical workforce; surgical in-novation; decision-making

(This special issue belongs to the Section Emergency Medicine)

Displaying special issue 1351-1400 on page 28 of 30.

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