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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Changing Landscape of Biliary Cancers

edited by Arvind Arora

submission deadline 20 Jun 2026 | Viewed by 48 | Submission Open

Keywords: biliary tract cancer; cholangiocarcinoma; gallbladder cancer; precision oncology; molecular profiling; immunotherapy; targeted therapy; clinical trials; multidisciplinary care; early detection; global oncology

(This special issue belongs to the Section Oncology)

Clinical Research Advances in Gynecologic Oncology

edited by

Maciej Skrzypczak

submission deadline 20 Jun 2026 | Viewed by 48 | Submission Open

Keywords: ovarian cancer; endometrial cancer; breast cancer; molecular biology; gynecological cancers

(This special issue belongs to the Section Oncology)

Stroke Care: From Acute Interventions to Long-Term Recovery

edited by

Aikaterini Theodorou

and

Georgios Tsivgoulis

submission deadline 20 Jun 2026 | Viewed by 47 | Submission Open

Keywords: cerebrovascular diseases; acute ischemic stroke; intravenous thrombolysis; endovascular thrombectomy; intracerebral hemorrhage; etiology; cerebral amyloid angiopathy; stroke rehabilitation

(This special issue belongs to the Section Clinical Neurology)

Cardiovascular Disease in the Elderly: Cardiogeriatric Assessment, Prevention, Treatment Outcomes and Perspectives

edited by Georgia Vamvakou

submission deadline 20 Jun 2026 | Viewed by 47 | Submission Open

Keywords: cardiovascular diseases; elderly patients; cardiogeriatric assessment; diagnosis and therapeutic planning; healthy aging; digital medicine

(This special issue belongs to the Section Cardiovascular Medicine)

Endoscopic Management of Pancreaticobiliary Disease: Updates and Future Directions

edited by

Keisuke Iwata

submission deadline 20 Jun 2026 | Viewed by 46 | Submission Open

Keywords: pancreaticobiliary disease; ERCP; interventional EUS; tissue acquisition; early detection of pancreaticobiliary malignancy; management of AEs

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current and Emerging Treatment Options in Pancreatic Cancer

edited by Venkata C.K. Sunkesula

submission deadline 20 Jun 2026 | Viewed by 44 | Submission Open

Keywords: pancreas surgery; pancreatic cystic lesions; chronic pancreatitis; pancreatic cancer; EUS-guided; fine-needle ablation; endoscopic radiofrequency ablation; minimal invasive surgery; pancreatic intraepithelial neoplasia

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Neuroimmunological Disorders: Mechanisms and Therapies

edited by

Christos Bakirtzis

and

Marina Kleopatra Boziki

submission deadline 20 Jun 2026 | Viewed by 43 | Submission Open

Keywords: neuroinflammatory; multiple sclerosis; neuromyelitis optica spectrum disorders; mog associated disease; autoimmune/paraneoplastic encephalitis

(This special issue belongs to the Section Clinical Neurology)

Clinical Advancements in Anesthesia and Pain Management

edited by Brittany L. Willer and Vidya T. Raman

submission deadline 20 Jun 2026 | Viewed by 42 | Submission Open

Keywords: perioperative innovation; regional and multimodal analgesia; translational anesthesiology; artificial intelligence in anesthesia; patient-centered pain management

(This special issue belongs to the Section Anesthesiology)

New Advances in Oral and Facial Surgery: 2nd Edition

edited by

Olindo Massarelli

submission deadline 20 Jun 2026 | Viewed by 41 | Submission Open

Keywords: squamous cell carcinoma; oro-pharyngeal tumors; skin tumors; plastic and reconstructive surgery; facial plastic surgery; facial reanimation; facial nerve palsy; head and neck surgery; maxillofacial surgery; aesthetic surgery; orthognatic surgery; dental implant surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Current and Emerging Management Strategies in Gynecologic Oncology

edited by Grzegorz Szewczyk

submission deadline 20 Jun 2026 | Viewed by 40 | Submission Open

Keywords: gynecologic oncology; surgical approach; molecular diagnostics; novel therapies; rare gynecological cancers; risk factors

(This special issue belongs to the Section Obstetrics & Gynecology)

New Concepts in the Diagnosis and Treatment of Orthopedic Diseases in Children—2nd Edition

edited by

Sergio De Salvatore

and

Laura Ruzzini

submission deadline 20 Jun 2026 | Viewed by 39 | Submission Open

Keywords: pediatric orthopedics; flatfoot; genu valgum; genu varum; hip dysplasia; clubfoot; early onset scoliosis; Scheuermann disease; perthes; epiphysiolysis; scoliosis; pediatric trauma

(This special issue belongs to the Section Clinical Pediatrics)

Hematoinflammatory Diseases: Bridging Autoimmunity and Autoinflammation

edited by Andrés González García and

José Hernández-Rodríguez

submission deadline 20 Jun 2026 | Viewed by 38 | Submission Open

Keywords: hematoinflammatory diseases; clonal hematopoiesis; vexas syndrome; castleman disease; Igg4-related disease; cytokine storm; autoinflammatory syndromes; immunopathogenesis; targeted therapies; biomarkers

(This special issue belongs to the Section Immunology & Rheumatology)

Recent Progress in Anterior Cruciate Ligament Injury and Reconstruction

edited by Patrick Weninger

submission deadline 20 Jun 2026 | Viewed by 38 | Submission Open

Keywords: anterior cruciate ligament; ACL reconstruction; ACL repair; ACL preservation; orthobiologics; stem cells; rehabilitation

(This special issue belongs to the Section Sports Medicine)

Therapies for Heart Failure: Clinical Updates and Perspectives

edited by Cristina Tudoran, Stela Iurciuc and Dragos Cozma

submission deadline 20 Jun 2026 | Viewed by 38 | Submission Open

Keywords: mechanisms of heart failure; new therapies for heart failure; chronic and acute heart failure; new approaches to managing heart failure patients; special populations; clinical outcome

(This special issue belongs to the Section Cardiology)

Clinical Advances in Endocarditis: From Diagnosis to Treatment

edited by Ram Sharony and Katia Orvin

submission deadline 20 Jun 2026 | Viewed by 36 | Submission Open

Keywords: endocarditis; infective endocarditis; prosthetic valve endocarditis; TAVR endocarditis; advanced cardiac imaging

(This special issue belongs to the Section Cardiology)

Cardiotoxicity Within Cardio-Oncology: Clinical Advances from Prediction to Management

edited by

Massimiliano Camilli

submission deadline 20 Jun 2026 | Viewed by 35 | Submission Open

Keywords: cardio-oncology; cardiotoxicity; cancer therapy– related cardiac dysfunction; heart failure in cancer patients; biomarkers; multimodality imaging; risk stratification; cardioprotection; cancer survivors' care; multidisciplinary approach

(This special issue belongs to the Section Cardiology)

Clinical Frontiers in Myocardial Infarction: From Acute Revascularization to Long-Term Secondary Prevention

edited by

Nikolaos Stalikas

submission deadline 20 Jun 2026 | Viewed by 34 | Submission Open

Keywords: complete revascularization; myocardial infarction; vulnerable plaque; imaging guided PCI; biomarkers; secondary prevention; microvascular disease; endothelial dysfunction

(This special issue belongs to the Section Cardiology)

Advances in Cardiovascular Rehabilitation: The Central Role of Exercise in Prevention and Care

edited by Massimo Pistono

submission deadline 20 Jun 2026 | Viewed by 34 | Submission Open

Keywords: cardiac rehabilitation; secondary prevention; physical exercise; cardiovascular health; aerobic exercise; cardio-oncology rehabilitation

(This special issue belongs to the Section Cardiovascular Medicine)

Advances in the Field of Cariology

edited by

Aline de Castilho

and

Frank Lippert

submission deadline 20 Jun 2026 | Viewed by 33 | Submission Open

Keywords: dental caries; caries diagnosis; caries risk assessment; minimally invasive dentistry; preventive strategies

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Focus on Multiple Myeloma: Diagnosis, Therapy and Clinical Outcome

edited by

Martina Kleber

submission deadline 20 Jun 2026 | Viewed by 33 | Submission Open

Keywords: multiple myeloma; novel therapies; treatment approach; prognosis; clinical outcome

(This special issue belongs to the Section Hematology)

Arterial Stiffness and Cardiovascular Risk: New Advances and Challenges

edited by

Andrea Grillo

submission deadline 20 Jun 2026 | Viewed by 32 | Submission Open

Keywords: arterial stiffness; vascular aging; anti-inflammation; cardiovascular risk; personalized medicine

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Rehabilitation Strategies and Exercise for Stroke Recovery

edited by

Dimitrios I. Tsiptsios

submission deadline 20 Jun 2026 | Viewed by 32 | Submission Open

Keywords: stroke; stroke rehabilitation; exercise; biomarkers; rehabilitation outcomes

(This special issue belongs to the Section Clinical Rehabilitation)

Atrial Fibrillation and Its Complications: Preventive Strategies and Relative Evidence—2nd Edition

edited by Roberto Galea

submission deadline 20 Jun 2026 | Viewed by 31 | Submission Open

Keywords: atrial fibrillation; catheter ablation; oral anticoagulation; left atrial appendage closure; stroke prevent

(This special issue belongs to the Section Cardiology)

Cancer Stem Cells and Cellular Therapies in Cancer: Advances and Clinical Prospects

edited by Agnieszka Rybarczyk and Piotr Wierzbicki

submission deadline 20 Jun 2026 | Viewed by 31 | Submission Open

Keywords: cancer stem cells; cell based therapies; innovative therapies in cancer; tumor microenvironment; cell based therapies; preclinical models; immune-based therapies; treatment resistance

(This special issue belongs to the Section Oncology)

Innovative Interventional Approaches in the Treatment of Cardiac Arrhythmias

edited by Karolina Weinmann-Emhardt and Jonas Wormann

submission deadline 20 Jun 2026 | Viewed by 27 | Submission Open

Keywords: cardiac electrophysiology; catheter ablation; atrial fibrillation; ventricular tachycardia; pulmonary vein isolation; three-dimensional mapping; pulsed field ablation; radiofrequency ablation; clinical perspectives

(This special issue belongs to the Section Cardiovascular Medicine)

Towards a Better Understanding of Neuroinflammation in Mental Health

edited by Jesus Cobo

submission deadline 20 Jun 2026 | Viewed by 21 | Submission Open

Keywords: neuroinflammation; biomarkers; peripheral biomarkers; outcomes; bipolar disorders; major depression; mental health; schizophrenia; blood-based inflammatory index; lymphocyte subpopulation

(This special issue belongs to the Section Mental Health)

Clinical Advances and Future Challenges for Occupational Health

edited by

Gabriele D’Ettorre

and Vincenza Pellicani

submission deadline 20 Jun 2026 | Viewed by 18 | Submission Open

Keywords: work-related disease; precision medicine; gender differences; aging workforce; preventive strategies

(This special issue belongs to the Section Epidemiology & Public Health)

Advances in Peripheral Vascular Disease: Diagnosis, Management and Surgical Interventions

edited by Nikolaos Zacharias

submission deadline 20 Jun 2026 | Viewed by 14 | Submission Open

Keywords: atherosclerosis; peripheral artery disease; claudication; critical limb threatening ischemia; infrainguinal bypass; femoral stenting

(This special issue belongs to the Section Vascular Medicine)

Endovascular Stroke Treatment: Latest Advances and Challenges

edited by Daniele Giuseppe Romano and Giulia Frauenfelder

submission deadline 20 Jun 2026 | Viewed by 8 | Submission Open

Keywords: EVT (endovascular stroke treatment); thromboaspiration; thrombectomy; tandem lesion; rescue stenting; ICAD

(This special issue belongs to the Section Clinical Neurology)

Clinical Management of Vitreous and Retinal Disorders

edited by Samuel Asanad

submission deadline 20 Jun 2026 | Submission Open

Keywords: OCT; OCTA; AMD; neurodegenerative disease; surgical techniques; retinal detachment; retinal blood flow; retinal biomarkers; gene therapy

(This special issue belongs to the Section Ophthalmology)

Clinical Advances and New Perspectives in the Diagnosis and Treatment of Schizophrenia

edited by Pierre S. Chue and Oloruntoba J. Oluboka

submission deadline 22 Jun 2026 | Viewed by 25 | Submission Open

Keywords: psychopharmacology; schizophrenia; long-acting injectable therapy; recovery; team approach to care; integrated care; clozapine; habilitation; rehabilitation; early intervention

(This special issue belongs to the Section Mental Health)

Clinical Insights and Challenges into Cognitive and Mental Health in Older Adults

edited by Dariusz Krok

submission deadline 23 Jun 2026 | Viewed by 51 | Submission Open

Keywords: clinical insights; cognitive and mental health; older adults; psychosomatic interventions; person-centered care

(This special issue belongs to the Section Mental Health)

Clinical Advances of Aesthetic Plastic Surgery and Aesthetic Medicine

edited by Valentina Pinto and Rosalba Russo

submission deadline 25 Jun 2026 | Viewed by 122 | Submission Open

Keywords: aesthetic plastic surgery; aesthetic medicine; emerging technologies and devices in aesthetics; regenerative medicine and surgery; vulvovaginal surgery; complications in aesthetic medicine

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Multidisciplinary Care in Severe Traumatic Brain Injury Across the Continuum of Care: Acute, Rehabilitative, and Chronic Management

edited by Ryan Martin, Davin Quinn and Nicholas Race

submission deadline 25 Jun 2026 | Viewed by 76 | Submission Open

Keywords: severe traumatic brain injury; multidisciplinary; rehabilitation; advance practice providers; ancillary health; therapy; neuropsychology; nutrition

(This special issue belongs to the Section Brain Injury)

Diet and Nutritional Aspects in Cardiovascular-Kidney-Metabolic Diseases (CKM)

edited by Krishnaswami Vijayaraghavan

submission deadline 25 Jun 2026 | Viewed by 69 | Submission Open

Keywords: cardiovascular-kidney-metabolic diseases (CKM); obesity; diabetes and metabolic syndrome; dietary factors; nutritional aspects; food policy and food security; chronic kidney disease; heart disease; technology

(This special issue belongs to the Section Clinical Nutrition & Dietetics)

Cardiometabolic Disease and Atherosclerosis: Epidemiology, Prevention, Diagnosis, and Clinical Treatment—2nd Edition

edited by

Evangelos Oikonomou

and Konstantinos Mourouzis

submission deadline 25 Jun 2026 | Viewed by 66 | Submission Open

Keywords: atherosclerosis; obesity; cardiometabolic disease; prevention; diabetes mellitus; endothelium; arteriosclerosis; coronary artery disease

(This special issue belongs to the Section Cardiology)

Recent Clinical Advances in Cardiac Rehabilitation: 2nd Edition

edited by

Tomasz Rechciński

submission deadline 25 Jun 2026 | Viewed by 49 | Submission Open

Keywords: cardiac rehabilitation; kinesiotherapy; psychological support; lifestyle modifications; myocardial infarction; heart failure

(This special issue belongs to the Section Cardiology)

Geriatric Cardiology: Clinical Advances and Comprehensive Management

edited by

Iris Parrini

submission deadline 25 Jun 2026 | Viewed by 48 | Submission Open

Keywords: geriatric assessment; management of cardiovascular disease; cardiovascular health; geriatric cardiology; frailty evaluation and management

(This special issue belongs to the Section Geriatric Medicine)

Surgical Innovations in Pediatric Orthopedics

edited by

Hoon Park

submission deadline 25 Jun 2026 | Viewed by 46 | Submission Open

Keywords: pediatric orthopedics; surgical innovation; growth modulation; absorbable implant; 3D printing

(This special issue belongs to the Section Orthopedics)

Myopic Optic Neuropathy (MON) and Glaucomatous Optic Neuropathy (GON): Current Concepts and Clinical Implications

edited by

Etsuo Chihara

submission deadline 25 Jun 2026 | Viewed by 44 | Submission Open

Keywords: myopic optic neuropathy; glaucomatous optic neuropathy; tilting; axonal transport; lamina cribrosa

(This special issue belongs to the Section Ophthalmology)

Advances in Minimally Invasive and Endoscopic Neurosurgery

edited by Shunsuke Shibao

submission deadline 25 Jun 2026 | Viewed by 44 | Submission Open

Keywords: minimally invasive; endoscopic; keyhole; endonasal; transorbital; skull base; complications; surgical outcomes; technical innovations; robotic neurosurgery

(This special issue belongs to the Section Clinical Neurology)

Oral Health and Systemic Diseases: Clinical Insights

edited by

Fabio Piras

submission deadline 25 Jun 2026 | Viewed by 43 | Submission Open

Keywords: oral health; endodontics; orthodontic; periodontal disease; dental caries

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Diagnosis and Management of Corneal Diseases

edited by Nicola Cardascia

submission deadline 25 Jun 2026 | Viewed by 38 | Submission Open

Keywords: corneal surgery; lamellar keratoplasty; bioengineered corneal grafts; regenerative medicine; cell-based therapies; tissue-based therapies; Intraoperative imaging; corneal wound healing; lmmune modulation; graft survival; translational research; multimodal diagnostics; clinical outcomes; corneal transparency restoration; ophthalmic surgical innovation

(This special issue belongs to the Section Ophthalmology)

Advances in Immunohematology: From Pathophysiology to Tailored Treatments

edited by

Giorgio Costagliola

submission deadline 25 Jun 2026 | Viewed by 33 | Submission Open

Keywords: autoimmune cytopenia; hemophagocytic lymphohistiocytosis; inborn errors of immunity; lymphoproliferative diseases; malignancy; monoclonal antibodies; secondary immunodeficiency; vaccination

(This special issue belongs to the Section Immunology & Rheumatology)

Upper Airway Management in Obstructive Sleep Apnea: Latest Advances and Future Perspectives

edited by Shintaro Chiba

submission deadline 25 Jun 2026 | Viewed by 30 | Submission Open

Keywords: obstructive sleep apnea (OSA); sleep surgery; upper airway stimulation (UAS); upper airway physiology

(This special issue belongs to the Section Respiratory Medicine)

Technological Advancements and Clinical Innovations in Diagnostic and Interventional Radiology: 2nd Edition

edited by

Massimo Venturini

and

Federico Fontana

submission deadline 25 Jun 2026 | Viewed by 29 | Submission Open

Keywords: artificial intelligence; radiomics; image fusion; spectral computed tomography; functional magnetic resonance im-aging; CO2 angiography; balloon-occluded transcatheter arterial chemoembolization

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Cancer Prevention and Early Detection: Epidemiological Approaches and Public Health Strategies

edited by

Carmen Martos

and

Francesco Giusti

submission deadline 25 Jun 2026 | Viewed by 27 | Submission Open

Keywords: cancer prevention; cancer screening; risk factors; cancer treatment; health information systems; cancer registry; cancer inequalities

(This special issue belongs to the Section Epidemiology & Public Health)

Cystic Fibrosis: Management Strategies and Patient Outcomes

edited by Marta Rachel

submission deadline 25 Jun 2026 | Viewed by 27 | Submission Open

Keywords: cystic fibrosis; multidisciplinary care; personalized medicine; patient outcomes; telemedicine; pediatric pulmonology; CFTR modulators; chronic disease management

(This special issue belongs to the Section Respiratory Medicine)

Clinical Management of Traumatic Brain Injury

edited by Adam James Wells and Peter Hutchinson

submission deadline 25 Jun 2026 | Viewed by 25 | Submission Open

Keywords: traumatic brain injury; clinical management TBI; neurocritical care; neuromonitoring; trauma neurosurgery; artificial intelligence

(This special issue belongs to the Section Clinical Neurology)

Clinical Advancements in Laparoscopic Surgery for Gastrointestinal Diseases

edited by

Nikolaos Pararas

submission deadline 25 Jun 2026 | Viewed by 22 | Submission Open

Keywords: laparoscopic surgery; minimally invasive surgery; gastrointestinal diseases; colorectal cancer; gastric cancer; robotic surgery; fluorescence imaging; endoscopic-laparoscopic hybrid surgery; surgical oncology; future perspectives

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Displaying special issue 1351-1400 on page 28 of 31.

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