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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Bariatric Surgery: Current Status and Emerging Clinical Trends

edited by Collin E. M. Brathwaite

submission deadline 25 Jun 2026 | Viewed by 10 | Submission Open

Keywords: bariatric surgery; metabolic surgery; obesity; GLP-1 receptor agonists; robotic surgery; revisional surgery; weight regain; metabolic mechanisms; enhanced recovery; surgical innovation

(This special issue belongs to the Section General Surgery)

Human Immunodeficiency Virus: From Clinical Studies to Patient Outcomes

edited by Vítor Duque

submission deadline 25 Jun 2026 | Submission Open

Keywords: HIV/AIDS; clinical trials; patient outcomes; clinical translational research

(This special issue belongs to the Section Infectious Diseases)

Integrating Artificial Intelligence and Contextual Factors in Emergency Care

edited by Ancor Sanz-García and

José Luis Martín-Conty

submission deadline 25 Jun 2026 | Submission Open

Keywords: emergency care; artificial intelligence; early warning systems; data-driven healthcare; predictive analytics

(This special issue belongs to the Section Emergency Medicine)

Advances in General and Regional Anaesthesia

edited by Michał Jan Stasiowski,

Nikola Zmarzły

and

Beniamin Oskar Grabarek

submission deadline 26 Jun 2026 | Viewed by 49 | Submission Open

Keywords: general anaesthesia; regional anaesthesia; ropivacaine; bupivacaine; postoperative pain; postoperative nausea and vomiting; preventive analgesia; rescue opioid analgesia; total intravenous anaesthesia; inhalational anaesthesia

(This special issue belongs to the Section Anesthesiology)

Youth Sports Injuries: From Prevalence to Prevention

edited by Swarup Mukherjee and

Gregory C. Bogdanis

submission deadline 30 Jun 2026 | 4 articles | Viewed by 10497 | Submission Open

Keywords: youth sports injuries; musculoskeletal injuries; injury prevention; sport safety; youth athletes

(This special issue belongs to the Section Sports Medicine)

Ergonomics and Low Back Pain: Integrative Approaches to Prevention, Assessment and Management

edited by

Janan Abbas

and

Deborah Alperovitch

submission deadline 30 Jun 2026 | Viewed by 51 | Submission Open

Keywords: advanced in diagnostic methods; therapeutic innovations; multidisciplinary and personalized care models; prevention and rehabilitation; non-pharmacological strategies; ergonomics; biomechanics

(This special issue belongs to the Section Orthopedics)

Integrating a One Health Approach into Antimicrobial Stewardship and Shared Care in Wound Management

edited by Joanna F. Blackburn

submission deadline 30 Jun 2026 | Viewed by 37 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial resistance; one health; shared care; wound care; wound care management; chronic wound care; acute wound care; digital health; wound diagnostics; antimicrobials; antibiotics

(This special issue belongs to the Section Dermatology)

Clinical Advances in Aortic Disease and Revascularization: 2nd Edition

edited by Andrej Udelnow

submission deadline 30 Jun 2026 | Viewed by 32 | Submission Open

Keywords: aortic disease; aortic aneurysm; endovascular aortic repair; atherosclerosis; aortic dissections; overall survival; quality of life; intravascular ultrasound

(This special issue belongs to the Section Vascular Medicine)

New Clinical Insights into Acute Respiratory Failure

edited by

Christophe Guervilly

submission deadline 30 Jun 2026 | Submission Open

Keywords: acute respiratory failure; pathophysiology; advances respiratory monitoring; respiratory support strategies; respiratory mechanics; mechanical ventilation; respiratory drive; patient-ventilator asynchrony

(This special issue belongs to the Section Intensive Care)

Modern Challenges in Pediatric Endocrinology: From Growth Disorders to Metabolic Dysregulation

edited by Katarzyna A. Majewska and Piotr Fichna

submission deadline 2 Jul 2026 | Viewed by 27 | Submission Open

Keywords: growth hormone deficiency; growth hormone therapy; short stature; obesity; obesity complications; obesity treatment; insulin resistance; prediabetes; type 1 diabetes; type 2 diabetes; hypothyroidism; hyperthyroidism; autoimmune thyroiditis; puberty disorders

(This special issue belongs to the Section Clinical Pediatrics)

Emerging Biomarkers and Novel Diagnostic Tools in Respiratory Diseases: From Bench to Bedside

edited by

Silvano Dragonieri

and

Andras Bikov

submission deadline 10 Jul 2026 | Viewed by 39 | Submission Open

Keywords: respiratory diseases; biomarkers; non-invasive approaches; novel diagnostic tests; precision medicine; personalized therapy; disease phenotyping; diagnostic tools; functional biomarkers; imaging biomarkers; molecular biomarkers

(This special issue belongs to the Section Respiratory Medicine)

Visualizing Cardiac Function: Advances in Modern Imaging Diagnostics

edited by Dafni Charisopoulou and

Michael Henein

submission deadline 10 Jul 2026 | Viewed by 34 | Submission Open

Keywords: cardiac imaging; echocardiography; coronary artery disease; valve disease; heart failure

(This special issue belongs to the Section Cardiology)

Endoscopic Therapy in Gastroesophageal Reflux Disease (GERD): Current Evidence, Techniques, and Future Perspectives

edited by Pier Alberto Testoni

submission deadline 10 Jul 2026 | Viewed by 26 | Submission Open

Keywords: gastroenterology; gastroesophageal reflux disease; GERD; esophageal diseases; endoscopic therapy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Gynecologic Cancers: Integrating Established Standards and Innovative Approaches

edited by Radu Vladareanu and Liviu Bilteanu

submission deadline 10 Jul 2026 | Viewed by 6 | Submission Open

Keywords: gynecological cancers; cervical cancer; ovarian cancer; endometrial cancer; vulvar and vaginal tumors; uterine sarcoma; fertility preservation; robotic surgery; image-guided radiotherapy (IGRT); brachytherapy; proton and FLASH radiotherapy; immunotherapy; radiomics; artificial intelligence; digital twin; multimodal treatment; survivorship and quality of life

(This special issue belongs to the Section Oncology)

Personalized Medicine: Future Perspectives on Personalized Oral and Maxillofacial Surgery

edited by

Cosmin Ioan Faur

, Rareș Calin Roman and Mihaela Carmen Hedeşiu

submission deadline 15 Jul 2026 | 1 articles | Viewed by 380 | Submission Open

Keywords: head and neck surgery; head and neck oncology; head and neck reconstructions; personalized medicine; artificial intelligence; head and neck trauma; integrative medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Aortic Dissection: Current Trends, Complexities, and Future Directions

edited by Aung Ye Oo

submission deadline 15 Jul 2026 | Viewed by 47 | Submission Open

Keywords: aortic dissection; aortic surgery; hybrid and endovascular repair; diagnostic delay; systems of care; patient safety; biomarkers and imaging; postoperative outcomes; multidisciplinary collaboration in aortic disease management

(This special issue belongs to the Section Cardiovascular Medicine)

Fertility Challenges: Modern Management Strategies and Assisted Reproductive Technologies

edited by

Luigi Carbone

submission deadline 15 Jul 2026 | Viewed by 41 | Submission Open

Keywords: infertility; assisted reproductive technologies (ARTs); ovarian reserve; antral follicle count (AFC); anti-mullerian hormone (AMH); fertility preservation; IVF pregnancy; ovarian stimulation; embryo selection

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Approaches to Prevention and Management of Postoperative Complications in Minimally Invasive Surgery

edited by Shingo Tsujinaka

submission deadline 15 Jul 2026 | Viewed by 33 | Submission Open

Keywords: minimally invasive surgery; postoperative complications; preventive measures; risk assessment; surgical techniques; patient optimization; complication management; surgical outcomes; patient satisfaction; patient-reported outcomes

(This special issue belongs to the Section General Surgery)

Measuring Recovery After Arthroplasty: Optimal Tools and Timing of Outcome Assessment

edited by

Nicholas David Clement

submission deadline 15 Jul 2026 | Viewed by 30 | Submission Open

Keywords: arthroplasty; hip; knee; recovery; outcomes; assessment

(This special issue belongs to the Section Orthopedics)

Current Challenges and Advancements in Stroke Prevention and Cerebrovascular Disorders

edited by

Ewelina Bak

and Sylwia Krzemińska

submission deadline 15 Jul 2026 | Viewed by 25 | Submission Open

Keywords: risk factors; secondary prevention; health education; health behaviors

(This special issue belongs to the Section Clinical Rehabilitation)

Neurosurgery Advancements: Techniques and Patient Outcomes

edited by Vianney Gilard

submission deadline 15 Jul 2026 | Viewed by 22 | Submission Open

Keywords: neurosurgery; minimally invasive surgery; endoscopic spine surgery; intraoperative imaging; neuro-oncology; functional neurosurgery; neurovascular surgery; patient outcomes

(This special issue belongs to the Section Clinical Neurology)

Multiple Sclerosis: Current Diagnosis, Treatment, and Future Options

edited by Przemysław Puz,

Nikolaos Grigoriadis

and

Eduardo Agüera-Morales

submission deadline 15 Jul 2026 | Viewed by 16 | Submission Open

Keywords: multiple sclerosis; magnetic resonance imaging (MRI); remyelination; biomarkers; neuroprotection

(This special issue belongs to the Section Clinical Neurology)

Understanding Dermatitis: Symptoms and Effective Treatment Options

edited by

Emi Sato

and Shinichi Imafuku

submission deadline 15 Jul 2026 | Viewed by 14 | Submission Open

Keywords: dermatitis; atopic dermatitis; psoriasis; prurigo; JAK inhibitors; real world data

(This special issue belongs to the Section Dermatology)

Total Hip Arthroplasty Today: Trends, Challenges, and Future Directions

edited by

Seung-Jae Lim

submission deadline 15 Jul 2026 | Submission Open

Keywords: complex hip arthroplasty; surgical technique; innovative implant; new technology; robotic surgery; navigation surgery; artificial intelligence; complications; periprosthetic joint infection; periprosthetic fracture; dislocation

(This special issue belongs to the Section Orthopedics)

Glaucoma: Advances in Diagnosis, Management, and Vision Preservation

edited by

Masaki Tanito

and

Takuhei Shoji

submission deadline 15 Jul 2026 | Submission Open

Keywords: glaucoma diagnosis; OCT and OCT angiography; laser therapies (SLT; micropulse; cyclophotocoagulation; etc.); minimally invasive glaucoma surgery (MIGS); long-tube devices; artificial intelligence and imaging; pharmacological therapy; visual field and retinal ganglion cell function

(This special issue belongs to the Section Ophthalmology)

Minimally Invasive Spine Surgery: Evidence, Advances and Controversies

edited by

Miltiadis Georgiopoulos

, Constantine Constantoyannis,

Mark A. MacLean

and Oliver Lasry

submission deadline 20 Jul 2026 | Viewed by 176 | Submission Open

Keywords: spine surgery; minimally invasive; MIS; MISS; endoscopic; tubular; fusion; laminectomy; discectomy; decompression; percutaneous; robotic; robotic-assisted; navigation; augmented-reality

(This special issue belongs to the Section Clinical Neurology)

Current Concepts in Melanoma: Innovations in Early Detection, Prognosis and Management

edited by Babar Khan Rao

submission deadline 20 Jul 2026 | Viewed by 104 | Submission Open

Keywords: melanoma; early detection; non-invasive diagnostic innovations; artificial intelligence-assisted diagnosis; melanoma management

(This special issue belongs to the Section Dermatology)

Exercise for Healthy Aging: Clinical Physiology, Functional Outcomes, and Implications for Clinical Practice

edited by

Jerónimo Aragón-Vela

and

Rafael A. Casuso

submission deadline 20 Jul 2026 | Viewed by 78 | Submission Open

Keywords: exercise; healthy aging; functional independence; mitochondrial adaptations; physical activity interventions; neuromuscular function; cardiorespiratory fitness; metabolic health; biomarkers of aging

(This special issue belongs to the Section Sports Medicine)

Pre-Hospital and In-Hospital Emergency Care Research

edited by

Marcus Eng Hock Ong

Fahad Javaid Siddiqui

and Yohei Okada

submission deadline 20 Jul 2026 | Viewed by 64 | Submission Open

Keywords: pre-hospital; in-hospital; emergency care; emergency medical services; acute care

(This special issue belongs to the Section Emergency Medicine)

Cataract and Refractive Surgery, and Intraocular Lens (IOL) Implantation: Advancing Diagnosis and Management

edited by Olga Reitblat

submission deadline 20 Jul 2026 | Viewed by 58 | Submission Open

Keywords: cataract surgery; premium intraocular lenses (IOLs); IOL power calculation; visual outcomes; refractive cataract surgery; multifocal IOL; extended depth of focus (EDOF) IOL; toric IOL; full range; vision IOL; biometry

(This special issue belongs to the Section Ophthalmology)

Clinical Implications of Artificial Intelligence in Patient Care

edited by

Safa Elkefi

and

Luigi Lavorgna

submission deadline 20 Jul 2026 | Viewed by 51 | Submission Open

Keywords: artificial intelligence; clinical decision support; human factors; digital health; patient care; implementation science; medical informatics; trust in AI

(This special issue belongs to the Section Clinical Research Methods)

Management of Diabetes-Related Cardiovascular Disease: Current Treatment and Future Options

edited by Antonio J. Amor and Tonet Serés-Noriega

submission deadline 20 Jul 2026 | Viewed by 51 | Submission Open

Keywords: type 1 diabetes; type 2 diabetes; cardiovascular disease; biomarkers; atherosclerosis; cardioprotective drugs; vascular ultrasound

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Updates in Fractures: Orthopedics, Trauma Surgery, and Rehabilitation

edited by

Rahul Vaidya

submission deadline 20 Jul 2026 | Viewed by 47 | Submission Open

Keywords: orthopedic surgery; global orthopedic health; surgical techniques; outreach; inreach; artificial intelligence; robotics; outcome measures

(This special issue belongs to the Section Orthopedics)

Sarcopenia, Musculoskeletal, and Neuromuscular Disorders: Physical Therapy and Rehabilitation Perspectives

edited by

Do-youn Lee

and

Myoung-Kwon Kim

submission deadline 20 Jul 2026 | Viewed by 43 | Submission Open

Keywords: sarcopenia; musculoskeletal diseases; neuromuscular disorders; muscle mass; low back pain; neck pain; gait and balance; physical therapy; rehabilitation medicine

(This special issue belongs to the Section Clinical Rehabilitation)

Advances in the Management of Cough and Asthma

edited by Ebymar Arismendi

submission deadline 20 Jul 2026 | Viewed by 41 | Submission Open

Keywords: asthma; chronic cough; biomarkers; exacerbations; biologics; precision medicine; airway inflammation; pediatric asthma

(This special issue belongs to the Section Respiratory Medicine)

Thoracic Surgery Today: Innovations, Challenges, and Future Perspectives

edited by Jeffrey B. Velotta and

Ory Wiesel

submission deadline 20 Jul 2026 | Viewed by 39 | Submission Open

Keywords: thoracic surgery; minimally invasive thoracic surgery; innovation; esophageal surgery; robotic-assisted thoracic surgery; lung cancer; advanced techniques; thoracic surgical oncology; mediastinal surgery; mesothelioma surgery

(This special issue belongs to the Section General Surgery)

Clinical Recent Advances in the Surgical Treatment of Heart Valve Disease

edited by

Beatrice Bacchi

and Aleksander Dokollari

submission deadline 20 Jul 2026 | Viewed by 39 | Submission Open

Keywords: heart valve surgery; prosthetic valves; intervention surgery; minimally invasive and robotic surgery; valve repair and replacement

(This special issue belongs to the Section Cardiology)

Current Updates on Pediatric Neurological Disorders and Neurorehabilitation

edited by

Lidia Perenc

and

Justyna Podgórska-Bednarz

submission deadline 20 Jul 2026 | Viewed by 34 | Submission Open

Keywords: child neurological disorders; neurorehabilitation; neurogenetics; treatment; quality of life; rehabilitation teams; congenital brain disorders; trauma; movement disorders; cerebral palsy

(This special issue belongs to the Section Clinical Pediatrics)

Optimizing Outcomes in Pancreato-Biliary Care: Integrating Technology, Technique, and Personalized Approaches

edited by

Andrea Tufo

submission deadline 20 Jul 2026 | Viewed by 33 | Submission Open

Keywords: pancreato-biliary care; pancreatic diseases; biliary diseases; hepato-pancreato-biliary (HPB) surgery; interventional endoscopy; interventional radiology; minimally invasive surgery; EUS-guided procedures; ERCP; personalized care/personalized medicine; multidisciplinary care; clinical outcomes; robotics and AI in PB care

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current Advances and Future Perspectives in Cardiothoracic Surgery

edited by Tomislav Kopjar

submission deadline 20 Jul 2026 | Viewed by 32 | Submission Open

Keywords: cardiothoracic surgery; minimally invasive techniques; robotic-assisted surgery; personalized therapy; surgical innovation; prosthetic devices; perioperative management; transplantation; technological advances; postoperative care; surgical outcomes; future perspectives; healthcare disparities

(This special issue belongs to the Section General Surgery)

State of the Art in Spinal Cord Injuries: Clinical Rehabilitation and Management

edited by

Valerio Pisani

submission deadline 20 Jul 2026 | Viewed by 30 | Submission Open

Keywords: neurorehabilitation; assistive technologies; neuroplasticity; neuromodulation; spinal cord injury

(This special issue belongs to the Section Clinical Rehabilitation)

New Perspective of Oral and Maxillo-Facial Surgery：2nd Edition

edited by

Valentino Vellone

Umberto Committeri

and Alessandra Lucchese

submission deadline 20 Jul 2026 | Viewed by 29 | Submission Open

Keywords: maxillofacial surgery; esthetic surgery; orthognatic surgery; TMJ disorders; TMJ surgery; dental implant surgery; 3D imaging; printing applications; tissue engineering; personalized treatment planning; artificial intelligence; squamous cell carcinoma; skin tumors; plastic and reconstructive surgery; head and neck surgery; ENT surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Pneumonia: From Diagnosis to Treatment

edited by

Marie Carmen Valenza

Laura López-López

and

María Granados Santiago

submission deadline 20 Jul 2026 | Viewed by 28 | Submission Open

Keywords: pneumonia; diagnosis; treatment; multidisciplinary care; pulmonary rehabilitation

(This special issue belongs to the Section Respiratory Medicine)

Clinical Outcomes in Lumbar Spinal Stenosis Treatment

edited by Rafał Staszkiewicz and

Beniamin Oskar Grabarek

submission deadline 20 Jul 2026 | Viewed by 26 | Submission Open

Keywords: lumbar spinal stenosis; clinical outcomes; decompression surgery; conservative management; molecular biomarkers; inflammation and fibrosis; neurotrophic factors; personalized medicine; siganling pathways; quality of life

(This special issue belongs to the Section Orthopedics)

Integrating Artificial Intelligence into Plastic, Reconstructive, and Aesthetic Surgery: Innovations, Challenges, and Clinical Application

edited by

Roberto Cuomo

and

Gianluca Marcaccini

submission deadline 20 Jul 2026 | Viewed by 26 | Submission Open

Keywords: plastic; reconstructive; aesthetic surgery; artificial intelligence; AI in plastic surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Orthodontics: Current Management and Future Options

edited by Arūnas Vasiliauskas and Aistė Kavaliauskienė

submission deadline 20 Jul 2026 | Viewed by 24 | Submission Open

Keywords: digital orthodontics; clear aligner therapy; accelerated tooth movement; micro-implants; artificial intelligence; patient-centred outcomes; treatment efficiency

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Contactless Magnetocardiography and Related Novel Methods for Non-Invasive Experimental and Clinical Functional Imaging of Normal and Abnormal Cardiac Electrophysiology

edited by

Riccardo Fenici

Donatella Brisinda

and

Peter Fenici

submission deadline 20 Jul 2026 | Viewed by 24 | Submission Open

Keywords: magnetocardiography; non-invasive functional imaging of cardiac electrophysiology; arrhythmogenic mechanisms; atrial fibrillation; magnetoionography; antiarrhythmic drugs; artificial intelligence

(This special issue belongs to the Section Cardiology)

Orthodontic Treatment in Clinical Practice: Strategies for Achieving Optimal Outcomes

edited by Adith Venugopal

submission deadline 20 Jul 2026 | Viewed by 24 | Submission Open

Keywords: orthodontics; biomechanics; tooth movement; bone remodeling; malocclusions; smile

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Acute Coronary Syndrome(ACS): From Emergency Intervention to Long-Term Prevention

edited by Marco Ciardetti and Alessio Mattesini

submission deadline 20 Jul 2026 | Viewed by 23 | Submission Open

Keywords: acute coronary syndrome; primary percutaneous coronary intervention; antithrombotic therapy; secondary prevention; risk stratification

(This special issue belongs to the Section Cardiology)

Clinical Advances in Chronic Lymphocytic Leukemia: Focus on Elderly Frail Patients

edited by Driss Chaoui

submission deadline 20 Jul 2026 | Viewed by 19 | Submission Open

Keywords: CLL; elderly; frailty; guidelines; quality of life; IBTK; BCL2; antiCD20

(This special issue belongs to the Section Hematology)

Displaying special issue 1401-1450 on page 29 of 31.

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