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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Update on the Diagnosis and Treatment of Heart Failure
edited by Giulia Nardi and Alessio Mattesini
submission deadline 26 Feb 2026 | 3 articles | Viewed by 5706 | Submission Open
Keywords: ejection fraction; acute heart failure; multidisciplinary management; right heart failure; left ventricle remodeling systems; HF percutaneous treatment; pharmacotherapy; HF prevention; cardiomyopathies
(This special issue belongs to the Section Cardiovascular Medicine)
Unraveling Myopia: Current Science, Clinical Impact, and Future Horizons
edited by Neeraj K Singh and Pablo De Gracia
submission deadline 27 Feb 2026 | Viewed by 96 | Submission Open
Keywords: accommodation; contact lenses; ophthalmic lenses; myopia progression; epidemiology; myopia control interventions; pharmaceutical treatments; environmental and behavioral risk factors; imaging innovations in myopia
(This special issue belongs to the Section Ophthalmology)
Hysterectomy Surgery—Recent Developments and Emerging Trends
edited by , and Dimitrios Zacharakis
submission deadline 28 Feb 2026 | Viewed by 75 | Submission Open
Keywords: hysterectomy; minimally invasive hysterectomy; robotic surgery; vaginal hysterectomy; surgical innovation; perioperative care
(This special issue belongs to the Section Obstetrics & Gynecology)
Headache Disorders: New Advances in Management and Treatment Strategies: 2nd Edition submission deadline 28 Feb 2026 | Viewed by 61 | Submission Open
Keywords: headache; migraine; cluster headache; tension-type headache; post-traumatic headache; calcitonin gene-related peptide; monoclonal antibodies; preventive therapy; acute treatment; pathophysiology; neuromodulation; pain management; drug development; gepants; ditan
(This special issue belongs to the Section Clinical Neurology)
Current and Emerging Treatment Options in Chronic Liver Diseases
edited by Chandana B. Herath
submission deadline 28 Feb 2026 | Viewed by 43 | Submission Open
Keywords: liver disease; liver fibrosis; liver cirrhosis; portal hypertension; liver cancer; therapies; immunological therapies for liver cancer; diabetic liver; type 2 diabetes and obesity; spontaneous bacterial peritonitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Updates in Cardiovascular Computed Tomography (CT)
edited by
submission deadline 28 Feb 2026 | Viewed by 37 | Submission Open
Keywords: cardiovascular CT; coronary CTA; plaque imaging; artificial intelligence; low-dose imaging; structural heart disease; cardiac imaging; high-risk plaque; atherosclerosis; coronary artery disease; valve calcification; thrombus detection
(This special issue belongs to the Section Cardiovascular Medicine)
Towards a New Paradigm: Opioid-Free and Opioid-Sparing Strategies in Modern Anesthesia submission deadline 28 Feb 2026 | Viewed by 26 | Submission Open
Keywords: opioid-free anesthesia; opioid-sparing strategies; multimodal analgesia; regional anesthesia; non-opioid analgesics; enhanced recovery after surgery (ERAS); perioperative pain management; postoperative analgesia; anesthesia innovation; chronic pain prevention; patient-centered anesthesia; clinical outcomes in anesthesia
(This special issue belongs to the Section Anesthesiology)
New Advances and Clinical Outcomes of Pediatric Endocrinology
edited by
submission deadline 28 Feb 2026 | Viewed by 17 | Submission Open
Keywords: congenital hypothyroidism; rare bone diseases; growth hormone deficiency; endocrine sequelae of cancer treatments; disorders of sex development; central diabetes insipidus; gender dysphoria
(This special issue belongs to the Section Clinical Pediatrics)
Epidemiology Associated Risks and Intervention Strategies of Childhood Obesity
edited by , and Eduardo Guzmán-Muñoz
submission deadline 28 Feb 2026 | Viewed by 17 | Submission Open
Keywords: childhood obesity; overweight; eating disorders; nutritional programs; psychological interventions; physical activi-ty– exercise; sport; physical well-being; mental well-being; quality of life
(This special issue belongs to the Section Clinical Pediatrics)
Neuromuscular Diseases and Musculoskeletal Disorders
edited by
submission deadline 28 Feb 2026 | Viewed by 11 | Submission Open
Keywords: neuromuscular diseases; osteoporosis; fractures; muscle weakness; muscle intolerance; shoulder dysfunction; myopathy; physiotherapy; rehabilitation
(This special issue belongs to the Section Clinical Neurology)
New Insights into Head and Neck Surgery—2nd Edition submission deadline 28 Feb 2026 | Viewed by 10 | Submission Open
Keywords: otorhinolaryngology; head and neck surgery; ear surgery; sinonasal surgery; skull base surgery; salivary gland surgery; thyroid gland surgery; head and neck cancer surgery
(This special issue belongs to the Section General Surgery)
Emerging Therapies: Clinical Trials and Insights in Psoriasis
edited by and Elżbieta Krajewska-Kułak
submission deadline 28 Feb 2026 | Viewed by 7 | Submission Open
Keywords: psoriasis; clinical trials; biomarkers; psychodermatology; treatment; modern therapy; individualized therapy
(This special issue belongs to the Section Dermatology)
Clinical Therapeutic Advances of Mitral Regurgitation
edited by Angelo Squeri
submission deadline 28 Feb 2026 | Viewed by 3 | Submission Open
Keywords: mitral regurgitation; mitral valve prolapse; cardiovascular interventions; heart surgery; echocardiography; mag-netic resonance imaging; computed tomography
(This special issue belongs to the Section Cardiovascular Medicine)
Tumor Microenvironment—Current Status and Therapeutic Targets
edited by
submission deadline 28 Feb 2026 | Viewed by 2 | Submission Open
Keywords: tumor microenvironment (TME); cancer immunology; immune checkpoint inhibitors; cancer biology; targeted therapies
(This special issue belongs to the Section Oncology)
Oral Hygiene: Updates and Clinical Progress: 2nd Edition
edited by
submission deadline 15 Mar 2026 | Submission Open
Keywords: periodontal disease; dental caries; plaque control; oral hygiene practices; gingivitis; dental prophylaxis; oral health education
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Progress in Clinical Diagnosis and Therapy in Ophthalmology
edited by
submission deadline 16 Mar 2026 | Viewed by 56 | Submission Open
Keywords: ophthalmic imaging; artificial intelligence in ophthalmology; retinal diseases; corneal transplantation; glaucoma diagnostics; ocular therapeutics; personalized medicine; ocular genetics
(This special issue belongs to the Section Ophthalmology)
Modern Gynecological Surgery: Clinical Updates and Perspectives
edited by
submission deadline 20 Mar 2026 | Viewed by 31 | Submission Open
Keywords: gynecological diseases; gynecological surgery; surgical options; individual treatment; women’ s health care
(This special issue belongs to the Section Obstetrics & Gynecology)
Up-to-Date Research on Nerve Ultrasound
edited by and Eman A. Tawfik
submission deadline 20 Mar 2026 | Viewed by 10 | Submission Open
Keywords: peripheral nerve ultrasound; polyneuropathy; nerve trauma; plexus neuritis; nerve tumors; entrapment syndromes; ultrasound techniques; guidelines
(This special issue belongs to the Section Clinical Neurology)
Perspectives on the Diagnosis and Treatment of Cardiomyopathies
edited by Luca Arcari
submission deadline 20 Mar 2026 | Viewed by 7 | Submission Open
Keywords: cardiomyopathies; hypertrophic cardiomyopathy; dilated cardiomyopathy; cardiac amyloidosis; arrhythmogenic right ventricular cardiomyopathy; non-dilated left ventricular cardiomyopathy; cardiac magnetic resonance imaging; computed tomography; echocardiography; nuclear imaging
(This special issue belongs to the Section Cardiology)
Acute Pancreatitis and Its Complications: Current Diagnostics and Management
edited by
submission deadline 20 Mar 2026 | Viewed by 5 | Submission Open
Keywords: acute pancreatitis; pancreas; pancreatic and peripancreatic necrosis; management; less invasive percutaneous radiological and endoscopic approaches
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Bladder Cancer: Diagnosis and Treatments
edited by
submission deadline 20 Mar 2026 | Submission Open
Keywords: bladder cancer; urothelial cancer; radical cystectomy; targeted therapy; immunotherapy; non-muscle -invasive; muscle-invasive; chemotherapy
(This special issue belongs to the Section Nephrology & Urology)
Osteosarcoma: New Insights into Diagnosis and Treatment
edited by Lars M. Wagner
submission deadline 25 Mar 2026 | Submission Open
Keywords: osteosarcoma; tyrosine kinase inhibitors; immunotherapy; clinical trial design; intratumoral heterogeneity; liquid biopsy; metastasectomy; deep learning; translational research; targeted therapy
(This special issue belongs to the Section Oncology)
Degenerative Cervical Myelopathy and Traumatic Spinal Cord Injury: Recent Advances and Future Directions
edited by Nader Hejrati, and Maryam Seif
submission deadline 28 Mar 2026 | 1 articles | Viewed by 164 | Submission Open
Keywords: degenerative cervical myelopathy; traumatic spinal cord injury; clinical assessment; surgical management; non-operative management; neuroprotective therapies; neuroregenerative therapies; outcome prediction
(This special issue belongs to the Section Clinical Neurology)
Cardiovascular Autonomic Function: From Bench to Bedside—2nd Edition
edited by and
submission deadline 31 Mar 2026 | Viewed by 55 | Submission Open
Keywords: dysautonomia; heart rate variability; autonomic function testing; cardiovascular autonomic function; autonomic neuroscience; syncope; orthostatic hypotension; baroreflex; autonomic molecular mechanisms
(This special issue belongs to the Section Cardiology)
JSOPB 2025–2026 Congress Special Issue–Update on Organ Preservation and Transplantation submission deadline 31 Mar 2026 | Viewed by 48 | Submission Open
Keywords: organ preservation; transplantation; pharmacology; engineering; stem cell therapy
(This special issue belongs to the Section General Surgery)
New Insights into Clinical Application of Embolization Techniques
edited by Bedros Taslakian and Yan Epelboym
submission deadline 31 Mar 2026 | Viewed by 15 | Submission Open
Keywords: embolization; interventional radiology; musculoskeletal embolization; uterine artery embolization; prostate artery embolization; vascular malformations; catheter-directed therapy
(This special issue belongs to the Section Vascular Medicine)
Thoracic Radiochemoimmunotherapy for Non-Small Cell Lung Cancer (NSCLC): Evolving Techniques and Clinical Applications
edited by
submission deadline 31 Mar 2026 | Submission Open
Keywords: radiotherapy; radiology; oncology; non-small cell lung cancer; real-world data; immunotherapy; radiation dose escalation
(This special issue belongs to the Section Oncology)
Innovations in Parkinson’s Disease
edited by
submission deadline 15 Apr 2026 | Viewed by 18 | Submission Open
Keywords: Parkinson’ s disease; parkinsonism; patient-reported outcomes; wearable technology; disease-modifying therapies; non-pharmacological therapies; care delivery; models of care
(This special issue belongs to the Section Clinical Neurology)
The Latest Research on Male Infertility
edited by Gianmaria Salvio and Nicola delli Muti
submission deadline 20 Apr 2026 | Viewed by 11 | Submission Open
Keywords: idiopathic male infertility; unexplained male infertility; semen quality; testicular dysfunction; male hypogonadism; gonadal failure
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Selected Papers from the 3rd International Online Conference on Clinical Medicine submission deadline 28 Apr 2026 | Viewed by 167 | Submission Open
Keywords: cardiology; cardiovascular medicine; nephrology; urology; emergency medicine; nuclear medicine & radiology; general surgery; clinical rehabilitation; respiratory medicine; anesthesiology
New Advances in the Management of Voice Disorders: 2nd Edition submission deadline 30 Apr 2026 | Viewed by 43 | Submission Open
Keywords: voice disorders; laryngology; laryngoscope; acoustic analysis; dysphonia; voice surgery; diagnosis; treatment; rehabilitation; vocal folds; voice assessment/measures
(This special issue belongs to the Section Otolaryngology)
Understanding Syncope: Multidisciplinary Approaches to Diagnosis and Management
edited by and Laranjo Sergio
submission deadline 31 May 2026 | 2 articles | Viewed by 2217 | Submission Open
Keywords: syncope; diagnostic strategies; prognostication; treatment options; quality of life; wearable devices; artificial intelligence; autonomic dysfunction; orthostatic hypotension; POTS (postural orthostatic tachycardia syndrome)
(This special issue belongs to the Section Cardiovascular Medicine)
Dental Care: Oral and Systemic Disease Prevention: 2nd Edition
edited by
submission deadline 31 Dec 2026 | Viewed by 5 | Submission Open
Keywords: oral health; oral diseases; oral manifestations; systemic diseases; oral care; dental prevention; dental caries; periodontal disease; oral medicine; dentistry; oral microbiome; salivary diagnostics; AI-assisted tools
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
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