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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Autoimmune-Induced Alopecia and Emerging Therapies in Hair Loss—2nd Edition
edited by David Saceda-Corralo
submission deadline 25 May 2026 | Viewed by 29 | Submission Open
Keywords: autoimmune-induced alopecia; alopecia areata; cicatricial alopecia; occurs; hair loss; frontal fibrosing alopecia
(This special issue belongs to the Section Dermatology)
Musculoskeletal Imaging and Intervention: 2nd Edition submission deadline 25 May 2026 | Viewed by 25 | Submission Open
Keywords: ultrasound; invasive physiotherapy; minimally invasive surgical procedures; magnetic resonance; image analysis
(This special issue belongs to the Section Nuclear Medicine & Radiology)
New Advances in Congenital Heart Disease submission deadline 25 May 2026 | Viewed by 24 | Submission Open
Keywords: congenital heart disease; pediatric cardiology; adult congenital heart disease; cardiac surgery; interventional cardiology; long-term outcomes; cardiac imaging
(This special issue belongs to the Section Cardiology)
Acute and Chronic Heart Failure: Clinical Updates and Perspectives—2nd Edition
edited by Luigi Cappannoli and Cristina Aurigemma
submission deadline 25 May 2026 | Viewed by 23 | Submission Open
Keywords: acute heart failure; chronic heart failure; devices; drug therapy; percutaneous ventricular assist devices; cardiogenic shock; arrhythmias; ischemic heart disease
(This special issue belongs to the Section Cardiovascular Medicine)
Surgical Innovation and Clinical Outcomes in Plastic and Reconstructive Surgery
edited by Pari Naz Mohanna and Ayush Kapila
submission deadline 25 May 2026 | Viewed by 22 | Submission Open
Keywords: plastic and reconstructive surgery; microsurgery; breast reconstruction; surgical innovation; novel flap techniques
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Epilepsy and Cerebrovascular Disorders
edited by
submission deadline 25 May 2026 | Viewed by 19 | Submission Open
Keywords: epilepsy; cerebrovascular disorders; stroke; post-stroke epilepsy; neuroinflammation; neuroimaging; electroenceph-alography; biomarkers; antiepileptic treatment; translational neuroscience
(This special issue belongs to the Section Clinical Neurology)
Clinical Advances in the Management of Abdominal and Thoracoabdominal Aortic Aneurysms
edited by
submission deadline 25 May 2026 | Viewed by 18 | Submission Open
Keywords: abdominal aneurysm; thoraco-abdominal; computed-tomography angiography; branched endograft; branched endovascular aortic repair; fenestrated endograft; open surgery; 3-D printing
(This special issue belongs to the Section Vascular Medicine)
Multiple Sclerosis and Demyelinating Disease: Clinical Treatment and Management
edited by Sotirios Giannopoulos
submission deadline 25 May 2026 | Viewed by 15 | Submission Open
Keywords: multiple sclerosis; demyelinating disease; comorbidities; disease modifying treatments; neuromuscular disorder; myasthenia gravis
(This special issue belongs to the Section Clinical Neurology)
Non-Small Cell Lung Cancer (NSCLC): Recent Advances in Clinical Diagnosis and Treatment
edited by
submission deadline 25 May 2026 | Viewed by 14 | Submission Open
Keywords: novel screening tool; cancer biomarkers; predictive marker of immunotherapy; targeted therapy; radiotherapy; non-small cell lung cancer
(This special issue belongs to the Section Oncology)
Clinical Diagnosis and Treatment of Demyelinating Diseases
edited by and John S. Tzartos
submission deadline 25 May 2026 | Viewed by 13 | Submission Open
Keywords: demyelinating diseases of the CNS; demyelinating diseases of the PNS; multiple sclerosis; neuromyelitis optica spectrum disorders (NMOSD); myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD); clinical diagnosis; biomarkers; therapeutics
(This special issue belongs to the Section Clinical Neurology)
Clinical Advances in Personalized Psychiatry
edited by
submission deadline 25 May 2026 | Viewed by 12 | Submission Open
Keywords: personalized psychiatry; biomarkers; predictive modeling; precision diagnosis; neuroimaging biomarkers; effective treatments
(This special issue belongs to the Section Mental Health)
Current Perspectives on the Clinical Management of Respiratory Diseases
edited by
submission deadline 25 May 2026 | Viewed by 12 | Submission Open
Keywords: COPD; acute exacerbations; biomarkers; clinical trials; bronchiectasis; respiratory infections
(This special issue belongs to the Section Respiratory Medicine)
Advances in Kidney Transplantation: 2nd Edition
edited by Pedro Ruiz-Esteban, Domingo Hernández and Veronica López
submission deadline 25 May 2026 | Viewed by 8 | Submission Open
Keywords: kidney transplant; acute rejection; biomarkers; artificial intelligence; post-transplant complications; graft survival
(This special issue belongs to the Section Nephrology & Urology)
An Update to Trends and Strategies in Vascular and Endovascular Surgery
edited by Karin Pfister and Fiona Rohlffs
submission deadline 25 May 2026 | Viewed by 7 | Submission Open
Keywords: vascular surgery; endovascular surgery; carotid endarterectomy; peripheral vascular diseases; vascular imaging; aortic diseases; aortic aneurysm; arteriovenous malformation; pelvic venous disorder; endovenous procedures; pal-liative therapy concept
(This special issue belongs to the Section Vascular Medicine)
Cerebrovascular Disease: Symptoms, Diagnosis and Current Treatment—Second Edition
edited by Alba Scerrati and Giorgio Mantovani
submission deadline 28 May 2026 | Viewed by 15 | Submission Open
Keywords: ischemic stroke; cerebral aneurysms; cerebral vascular malformation; cerebral venous disease; cerebral venous thrombosis
(This special issue belongs to the Section Clinical Neurology)
Spine Surgery Innovations: Treatments and Technologies
edited by and Tomoyuki Asada
submission deadline 29 May 2026 | Viewed by 359 | Submission Open
Keywords: AI; robotics; navigation; muscle preservation; minimally invasive surgery; motion preservation; alignment targets; implant materials; bone growth factors; custom-made implants
(This special issue belongs to the Section Orthopedics)
Pediatric Hearing Loss: Advances in Early Detection, Intervention and Family-Centered Care submission deadline 30 May 2026 | Viewed by 8 | Submission Open
Keywords: pediatric hearing loss; early intervention; early identification of language and communication disorders; develop-mental language disorders; predictors of outcomes; newborn hearing screening; pediatric audiology
(This special issue belongs to the Section Otolaryngology)
Understanding Syncope: Multidisciplinary Approaches to Diagnosis and Management
edited by and Sérgio Laranjo
submission deadline 31 May 2026 | 3 articles | Viewed by 3281 | Submission Open
Keywords: syncope; diagnostic strategies; prognostication; treatment options; quality of life; wearable devices; artificial intelligence; autonomic dysfunction; orthostatic hypotension; POTS (postural orthostatic tachycardia syndrome)
(This special issue belongs to the Section Cardiovascular Medicine)
Advances in Male Infertility: Diagnosis, Management and ART Integration
edited by Despoina Mavrogianni and Sofoklis Stavros
submission deadline 31 May 2026 | Viewed by 1034 | Submission Open
Keywords: male infertility; assisted reproductive technologies (ART); intracytoplasmic sperm injection (ICSI); genetic testing; hormonal profiling; seminal biomarkers; sperm retrieval techniques; sperm selection; stem cell therapy; gene editing; reproductive endo-crinology; early pregnancy; implantation failure; recurrent miscarriage
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Personalized Management of Abdominal Surgery and Complications
edited by Ioannis Mantzoros and
submission deadline 31 May 2026 | Viewed by 62 | Submission Open
Keywords: personalized medicine; abdominal surgery; complications; emergency; innovative surgery
(This special issue belongs to the Section General Surgery)
Clinical Advances and Contemporary Applications of Echocardiography
edited by
submission deadline 31 May 2026 | Viewed by 45 | Submission Open
Keywords: echocardiography; speckle-tracking; three-dimensional; Doppler; cardiac; valve; vasculature
(This special issue belongs to the Section Cardiovascular Medicine)
Current Advances and Future Challenges in Heart Transplantation
edited by
submission deadline 31 May 2026 | Viewed by 34 | Submission Open
Keywords: heart transplantation; indication; surgical techniques; preoperative care; immunosuppressive regimens; mechanical circulatory support; donor assessment and management; cardiac donation after circulatory death; ex vivo machine perfusion; normothermic regional perfusion; cardiac xenotransplantation
(This special issue belongs to the Section Cardiology)
Early Prevention and Diagnosis of Atherosclerosis: From Clinical Progression to Patient Management submission deadline 31 May 2026 | Viewed by 15 | Submission Open
Keywords: atherosclerosis; atherothrombotic molecular pathways; cardiovascular risk; monitoring of goals; pharmacological and non-pharmacological prevention; carotid and peripheral interventions
(This special issue belongs to the Section Cardiovascular Medicine)
Diagnosis and Treatment of Pediatric Endocrine Disorders—Focus on Rare Conditions
edited by Sophia Sakka
submission deadline 1 Jun 2026 | Viewed by 721 | Submission Open
Keywords: pediatric endocrinology; diabetes mellitus in children; bone metabolism disorders; clinical diagnosis; therapeutic strategies; skeletal dysplasias; rare endocrine conditions; pediatric type 1 diabetes; rickets management; genetic conditions; pediatric hormone therapy; achondroplasia
(This special issue belongs to the Section Endocrinology & Metabolism)
New Insights on Pharmacologic and Non-pharmacologic Therapy of Advanced Heart Failure
edited by
submission deadline 5 Jun 2026 | Viewed by 2 | Submission Open
Keywords: advanced heart failure (AHF); mechanical circulatory support systems; heart transplantation (HTx); immunosuppression; cardiac allograft rejections
(This special issue belongs to the Section Cardiology)
Diabetes Mellitus and Emerging Health Challenges: A Multidisciplinary Perspective
edited by Katarzyna A. Majewska and
submission deadline 10 Jun 2026 | Viewed by 53 | Submission Open
Keywords: diabetes mellitus; type 1 diabetes; type 2 diabetes; diabetic complications; prediabetes; diabetes treatment; autoimmune diabetes
(This special issue belongs to the Section Endocrinology & Metabolism)
Transjugular Intrahepatic Portosystemic Shunt: Challenges and Perspectives—2nd Edition
edited by , Stefania Gioia and
submission deadline 15 Jun 2026 | Viewed by 15 | Submission Open
Keywords: hepatic encephalopathy; spontaneous portal-systemic shunts; transjugular intrahepatic portosystemic shunt; cirrhosis; portal hypertension; sarcopenia; myosteatosis; gastrointestinal bleeding; ascites; non cirrhotic portal hypertension
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Physiotherapy and Therapeutic Exercise in Modern Clinical Practice
edited by Andoni Carrasco Uribarren, and
submission deadline 20 Jun 2026 | Viewed by 35 | Submission Open
Keywords: exercise therapy; physiotherapy; therapeutic exercise; musculoskeletal disorders; musculoskeletal rehabilitation; pain management; patient-centered care; physiotherapy; rehabilitation technology
(This special issue belongs to the Section Orthopedics)
Clinical Advances in Endocarditis: From Diagnosis to Treatment
edited by Ram Sharony
submission deadline 20 Jun 2026 | Viewed by 18 | Submission Open
Keywords: endocarditis; infective endocarditis; prosthetic valve endocarditis; TAVR endocarditis; advanced cardiac imaging
(This special issue belongs to the Section Cardiology)
Clinical Advances and Challenges in Liver Transplantation: 3rd Edition
edited by
submission deadline 20 Jun 2026 | Viewed by 11 | Submission Open
Keywords: liver transplantation (LT); elderly donors; steatotic livers; donors after circulatory death (DCD); hepatocellular carcinoma (HCC); perioperative management
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Assisted Knee Arthroplasty: From Preoperative Planning to Postoperative Outcomes
edited by and Matteo Innocenti
submission deadline 20 Jun 2026 | Viewed by 11 | Submission Open
Keywords: assisted knee arthroplasty; robotic-assisted surgery; computer navigation; preoperative planning; patient-specific alignment; minimally invasive surgery; digital health technologies
(This special issue belongs to the Section Orthopedics)
Stroke Care: From Acute Interventions to Long-Term Recovery submission deadline 20 Jun 2026 | Viewed by 9 | Submission Open
Keywords: cerebrovascular diseases; acute ischemic stroke; intravenous thrombolysis; endovascular thrombectomy; intracerebral hemorrhage; etiology; cerebral amyloid angiopathy; stroke rehabilitation
(This special issue belongs to the Section Clinical Neurology)
Hematoinflammatory Diseases: Bridging Autoimmunity and Autoinflammation
edited by Andrés González García and
submission deadline 20 Jun 2026 | Viewed by 9 | Submission Open
Keywords: hematoinflammatory diseases; clonal hematopoiesis; vexas syndrome; castleman disease; Igg4-related disease; cytokine storm; autoinflammatory syndromes; immunopathogenesis; targeted therapies; biomarkers
(This special issue belongs to the Section Immunology & Rheumatology)
Advances in Rhinosinusitis and Nasal Polyposis: From Emerging Trends and Therapeutic Opportunities to Surgery
edited by Gian Luca Fadda, Giovanni Cavallo and Giuseppe Guida
submission deadline 20 Jun 2026 | Viewed by 6 | Submission Open
Keywords: nasal polyps; chronic rhinosinusitis; asthma; endoscopic sinus surgery; anatomical variation; biologic treatment; type-2 inflammation; paranasal sinuses; CRSwNP; late response; long term; remission; dupilumab; control
(This special issue belongs to the Section Otolaryngology)
Clinical Advances of Aesthetic Plastic Surgery and Aesthetic Medicine
edited by Valentina Pinto and Rosalba Russo
submission deadline 25 Jun 2026 | Viewed by 51 | Submission Open
Keywords: aesthetic plastic surgery; aesthetic medicine; emerging technologies and devices in aesthetics; regenerative medicine and surgery; vulvovaginal surgery; complications in aesthetic medicine
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Emerging Biomarkers and Novel Diagnostic Tools in Respiratory Diseases: From Bench to Bedside submission deadline 10 Jul 2026 | Viewed by 17 | Submission Open
Keywords: respiratory diseases; biomarkers; non-invasive approaches; novel diagnostic tests; precision medicine; personalized therapy; disease phenotyping; diagnostic tools; functional biomarkers; imaging biomarkers; molecular biomarkers
(This special issue belongs to the Section Respiratory Medicine)
Personalized Medicine: Future Perspectives on Personalized Oral and Maxillofacial Surgery
edited by , Rareș Calin Roman and Mihaela Carmen Hedeşiu
submission deadline 15 Jul 2026 | Viewed by 305 | Submission Open
Keywords: head and neck surgery; head and neck oncology; head and neck reconstructions; personalized medicine; artificial intelligence; head and neck trauma; integrative medicine
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Current Concepts in Melanoma: Innovations in Early Detection, Prognosis and Management
edited by Babar Khan Rao
submission deadline 20 Jul 2026 | Viewed by 44 | Submission Open
Keywords: melanoma; early detection; non-invasive diagnostic innovations; artificial intelligence-assisted diagnosis; melanoma management
(This special issue belongs to the Section Dermatology)
Improving Outcomes in Systemic Lupus Erythematosus: Latest Advances and Prospects in Relation to Comorbidity, Damage, and Quality of Life
edited by and Shaye Kivity
submission deadline 30 Jul 2026 | Viewed by 24 | Submission Open
Keywords: systemic lupus erythematosus; comorbidities; outcome measures; damage accrual; quality of life; cognitive im-pairment; infections and vaccination; treat-to-target; digital biomarkers
(This special issue belongs to the Section Immunology & Rheumatology)
Current Trends and Innovations in Coronary Artery Disease and Myocardial Ischemia: Second Edition
edited by
submission deadline 20 Aug 2026 | Viewed by 14 | Submission Open
Keywords: coronary artery disease; fractional flow reserve; invasive coronary angiography; cardiac CT; cardiac MRI
(This special issue belongs to the Section Cardiovascular Medicine)
Dental Care: Oral and Systemic Disease Prevention: 2nd Edition
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 877 | Submission Open
Keywords: oral health; oral diseases; oral manifestations; systemic diseases; oral care; dental prevention; dental caries; periodontal disease; oral medicine; dentistry; oral microbiome; salivary diagnostics; AI-assisted tools
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Aortic Diseases: Modern Strategies in Diagnosis, Management, and Prevention of Complications
edited by , Tilo Kölbel and José Ignacio F. Torrealba
submission deadline 20 Jul 2027 | Viewed by 37 | Submission Open
Keywords: aortic aneurysm; aortic dissection; genetic aortic disease; acute aortic syndromes; endovascular repair; complica-tions; outcomes
(This special issue belongs to the Section Vascular Medicine)
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