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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Advances in Hip and Knee Reconstructive Surgery: 2nd Edition

edited by Senthil Sambandam

submission deadline 31 Jan 2026 | Viewed by 17 | Submission Open

Keywords: knee; hip; joint arthroplasty; minimally invasive surgery; revision arthroplasty; periprosthetic joint infection; muscle injury; joint alignment; surgical advances; osteotomy; fracture; robotic-assisted surgery; perioperative optimization; telerehabilitation; aseptic loosening

(This special issue belongs to the Section Orthopedics)

Trauma Surgery: Strategies, Challenges and Vision of the Future

edited by Shai Factor and Yaniv S. Warschawski

submission deadline 31 Jan 2026 | Viewed by 10 | Submission Open

Keywords: orthopaedic surgery; fractures; injuries; upper limb; trauma

(This special issue belongs to the Section Clinical Research Methods)

Exercise, Injury and Rehabilitation: Integrated Perspectives in Sports Medicine

edited by

Cíntia França

and

Élvio Gouveia

submission deadline 3 Feb 2026 | Viewed by 59 | Submission Open

Keywords: sports medicine; biomechanics; injury prevention; exercise physiology; sports performance; load management; exercise prescription; return to play; recovery

(This special issue belongs to the Section Sports Medicine)

New Advances and Clinical Outcomes of Cardiothoracic Surgery

edited by Hee-Jung Kim and

Seung-Hyun Lee

submission deadline 5 Feb 2026 | Viewed by 32 | Submission Open

Keywords: cardiac surgery; coronary artery bypass grafting; heart valve surgery; aortic intervention; materials; precision medicine; artificial intelligence

(This special issue belongs to the Section General Surgery)

Physical Therapy in Neurorehabilitation: Innovations, Challenges and Opportunities

edited by

Daphne Bakalidou

Maria Gabriella Ceravolo

and

Pinelopi Vlotinou

submission deadline 6 Feb 2026 | Viewed by 13 | Submission Open

Keywords: neurorehabilitation; physical activity; neurocognitive rehabilitation; neurogenic bladder; fatigue; sexual dysfunction; accessibility

(This special issue belongs to the Section Clinical Neurology)

Application of Anticoagulation and Antiplatelet Therapy

edited by

Rossella Marcucci

and

Martina Berteotti

submission deadline 10 Feb 2026 | Viewed by 70 | Submission Open

Keywords: antiplatelets; anticoagulants; atherothrombosis; coronary artery disease; peripheral artery disease; cerebral artery disease; vitamin K antagonists; direct oral anticoagulants; clopidogrel; aspirin; ticagrelor; prasugrel

(This special issue belongs to the Section Cardiovascular Medicine)

Plastic and Reconstructive Surgery: Cutting-Edge Expert Perspective

edited by

Roberto Cuomo

and

Ishith Seth

submission deadline 10 Feb 2026 | Viewed by 61 | Submission Open

Keywords: plastic and reconstructive surgery; new perspectives; regeneration; microsurgery; oncoplastic; post bariatric; breast implant

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Hearing Disorders: Diagnosis, Management, and Future Opportunities: 4th Edition

edited by

George K. Psillas

submission deadline 10 Feb 2026 | Viewed by 42 | Submission Open

Keywords: middle ear surgery; otosclerosis; sensorineural hearing loss; sudden hearing; cochlear implant

(This special issue belongs to the Section Otolaryngology)

Clinical Advances in Spine Disorders—2nd Edition

edited by

Sokol Trungu

and

Luca Ricciardi

submission deadline 10 Feb 2026 | Viewed by 33 | Submission Open

Keywords: spine disorders; lumbar spine surgery; minimally invasive surgery; spine surgery; microneurosurgery

(This special issue belongs to the Section Clinical Neurology)

Recent Concepts in Ovarian Cancer: Epidemiology, Diagnosis, Treatment and Quality of Life

edited by Giulia Scotto and

Giorgio Valabrega

submission deadline 10 Feb 2026 | Viewed by 27 | Submission Open

Keywords: ovarian cancer; quality of life; multidisciplinary care; personalized medicine; PARP inhibitors

(This special issue belongs to the Section Oncology)

Management of Congenital Heart Disease (CHD)

edited by Sarah Nordmeyer and Marie Schafstedde

submission deadline 10 Feb 2026 | Viewed by 25 | Submission Open

Keywords: congenital heart disease; imaging; diagnostics; surgical innovations; minimally invasive interventions

(This special issue belongs to the Section Cardiovascular Medicine)

Infectious Disease Epidemiology: Current Updates and Perspectives

edited by

Agata Skrzat-Klapaczynska

and

Justyna Dominika Kowalska

submission deadline 10 Feb 2026 | Viewed by 20 | Submission Open

Keywords: infection prevention and control; infectious diseases epidemiology; public health; novel treatments

(This special issue belongs to the Section Infectious Diseases)

Clinical Advances in Pediatric Critical Care Medicine

edited by

Lama Elbahlawan

submission deadline 10 Feb 2026 | Viewed by 18 | Submission Open

Keywords: acute renal failure; acute respiratory failure; pediatric oncology; pediatric ICU; pediatric critical care medicine; multi-organ dysfunction

(This special issue belongs to the Section Clinical Pediatrics)

Advancements and Future Directions in Clinical Psychosis

edited by

Marco Colizzi

and

Alessandra Martinelli

submission deadline 10 Feb 2026 | Viewed by 9 | Submission Open

Keywords: clinical psychosis; schizophrenia spectrum disorders; early detection of psychosis; treatment-resistant psychosis; long-term outcomes; personalized psychiatry; digital mental health; AI in psychiatry; neurocognitive interventions; psychosocial therapies; translational psychiatry; interdisciplinary mental health; psychosis clinical trials; innova-tive diagnostic tools

(This special issue belongs to the Section Mental Health)

Pancreatic Disorder, Pancreatitis, and Pancreatic Cancer: Interconnections, Clinical Challenges, and Therapeutic Advances

edited by Cristian George Ţieranu and

Adrian Saftoiu

submission deadline 15 Feb 2026 | Viewed by 832 | Submission Open

Keywords: pancreatic disorder; pancreatitis; pancreatic cancer; translational research; diagnosis; treatment

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Catheter Ablation of Cardiac Arrhythmias: Current Updates and Perspectives: 2nd Edition

edited by

Shaojie Chen

submission deadline 15 Feb 2026 | Viewed by 46 | Submission Open

Keywords: ablation; arrhythmia; electrophysiology; atrial fibrillation; atrial flutter; atrial tachycardia; mapping; supraventricular tachycardia; ventricular arrhythmia

(This special issue belongs to the Section Cardiology)

Current Concepts and Updates in Eye Diseases

edited by Wiktor Stopyra,

Joanna Konopińska

and Anna Machalinski

submission deadline 15 Feb 2026 | Viewed by 39 | Submission Open

Keywords: corneal disease; glaucoma; cataract; uveitis; ocular oncology; retinal disorder; ocular treatment; eye surgery; ocular diagnostics

(This special issue belongs to the Section Ophthalmology)

Drug-Related Problems: Clinical Pharmacy and Safety of Pharmacotherapy

edited by

Mariola Drozd

and

Jakub Pawlikowski

submission deadline 15 Feb 2026 | Viewed by 37 | Submission Open

Keywords: adverse drug reaction; drug-related problems; drug formulation technology; safety of pharmacotherapy; clinical pharmacy; pharmaceutical care; pharmacology

(This special issue belongs to the Section Pharmacology)

Recent Advances in Refractive Surgery and Intraocular Lens Implantation

edited by Antonio Leccisotti

submission deadline 15 Feb 2026 | Viewed by 28 | Submission Open

Keywords: refractive surgery; intraocular lens implantation; keratectomy; cornea; ocular surgery; optical coherence tomography; laser surgery; KLEx (keratorefractive lenticule extraction); femtolasik

(This special issue belongs to the Section Ophthalmology)

State of the Art in Bladder Cancer: Diagnostics and Treatment Strategies

edited by

Angelo Porreca

submission deadline 15 Feb 2026 | Viewed by 23 | Submission Open

Keywords: bladder cancer; photodynamic diagnosis (PDD); bladder-sparing strategies; robotic-assisted surgery; single-port robotic cystectomy; older patients; immunotherapy; intravesical therapy; bladder preservation; minimally invasive urology; advanced bladder cancer; diagnostic innovation

(This special issue belongs to the Section Nephrology & Urology)

Periodontal Diseases and Systemic Health: Pathogenesis, Prevention and Management

edited by Saverio Cosola

submission deadline 15 Feb 2026 | Viewed by 16 | Submission Open

Keywords: periodontitis; dental implants; systemic inflammation; diabetes and periodontal disease; cardiovascular implications; pregnancy and oral health; host immune responses; preventive dentistry; implant-prosthetic rehabilitation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Diagnosis and Surgical Strategies Update on Ear Disorders: 2nd Edition

edited by

Eleonora M.C. Trecca

and

Andrea Albera

submission deadline 15 Feb 2026 | Viewed by 14 | Submission Open

Keywords: middle ear; inner ear; endoscopic ear surgery; cholesteatoma; Meniè re’ s disease; hearing loss; robotic surgery; oto-sclerosis

(This special issue belongs to the Section Otolaryngology)

Clinical Perspectives in Amyotrophic Lateral Sclerosis: Diagnosis, Management and Future Opportunities

edited by

Matthias Boentert

submission deadline 15 Feb 2026 | Viewed by 12 | Submission Open

Keywords: amyotrophic lateral sclerosis; early diagnosis; neuroimaging; biomarkers; treatment

(This special issue belongs to the Section Clinical Neurology)

Bariatric Surgery: Challenges and Future Trends

edited by Hugo Santos-Sousa

submission deadline 15 Feb 2026 | Viewed by 11 | Submission Open

Keywords: obesity; metabolic and bariatric surgery; sleeve gastrectomy; metabolic syndrome; novel surgical procedures; Nissen-sleeve fundoplication; Roux-en-Y gastric bypass distalization; single-anastomosis procedures

(This special issue belongs to the Section General Surgery)

New Insight into Pain and Chronic Pain Management

edited by

Eung Don Kim

submission deadline 15 Feb 2026 | Viewed by 8 | Submission Open

Keywords: chronic pain; pain management; pharmacological treatment; non-pharmacological interventions; neuromodula-tion; multidisciplinary approaches; personalized medicine; quality of life

(This special issue belongs to the Section Clinical Rehabilitation)

Kidney Transplantation: Current Challenges and Future Perspectives: 2nd Edition

edited by Alberto Piana and Angelo Territo

submission deadline 15 Feb 2026 | Viewed by 8 | Submission Open

Keywords: kidney transplantation; urologic cancers; organ preservation; surgical challenges; donor selection; long-term outcomes; complications; post-transplant care; technology

(This special issue belongs to the Section Nephrology & Urology)

Innovations in Perioperative Anesthesia: Advancing Non-Operating Room Anesthesia (NORA) and Regional Techniques

edited by Francesco Coppolino and

Vincenzo Pota

submission deadline 20 Feb 2026 | Viewed by 651 | Submission Open

Keywords: perioperative medicine; non-operating room anesthesia (NORA); ultrasound-guided regional anesthesia; fascial plane blocks; postoperative pain management

(This special issue belongs to the Section Anesthesiology)

Kidney Transplantation: State of the Art Knowledge

edited by

Georgios Koimtzis

, Georgios Geropoulos and Kyriakos Psarras

submission deadline 20 Feb 2026 | Viewed by 329 | Submission Open

Keywords: kidney transplantation; end-stage renal disease; immunosuppression; organ donation; graft survival; graft rejection

(This special issue belongs to the Section Nephrology & Urology)

Clinical Update on Cardiac Rehabilitation

edited by Bruno Bordoni

submission deadline 20 Feb 2026 | Viewed by 234 | Submission Open

Keywords: cardiac rehabilitation; cardiovascular disease; physiotherapy; interprofessional intervention; exercise training; nutritional counseling; psychosocial support; secondary prevention; rehabilitation modalities; rehabilitation tools

(This special issue belongs to the Section Clinical Rehabilitation)

Advances in Maternal–Fetal Medicine

edited by

C. Andrew Combs

submission deadline 20 Feb 2026 | Viewed by 69 | Submission Open

Keywords: maternal– fetal medicine; obstetric ultrasound; preterm birth; preeclampsia; pregnancy complications; artificial intelligence

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Advances and Future Perspectives of Ischemic Stroke

edited by

Marzia Baldereschi

submission deadline 20 Feb 2026 | Viewed by 58 | Submission Open

Keywords: acute ischemic stroke care; neuroimaging in ischemic stroke; alteplase and tenecteplase; endovascular treatments; recanalization and reperfusion; prognostication in stroke patients; blood– brain barrier in ischemic stroke; bi-omarkers in ischemic stroke; omics in stroke

(This special issue belongs to the Section Clinical Neurology)

Cancer Immunotherapy: Recent Advances and Clinical Challenges

edited by

Antonello Veccia

submission deadline 20 Feb 2026 | Viewed by 42 | Submission Open

Keywords: immune checkpoint inhibitors; solid tumors; early-stage disease; metastatic disease; prognostic factors; biomarkers; resistance mechanisms

(This special issue belongs to the Section Oncology)

Intrarenal Surgery for Kidney Stones and Other Kidney Diseases

edited by Razvan Multescu

submission deadline 20 Feb 2026 | Viewed by 37 | Submission Open

Keywords: intrarenal surgery; flexible ureteroscopy; percutaneous nephrolithotomy (PCNL); Mini-PCNL; thulium laser; ureteral access sheaths; flexible and navigable suction (FANS); upper urinary tract urothelial tumors

(This special issue belongs to the Section Nephrology & Urology)

Clinical Translation of Technological Innovations in Diabetes Therapeutics

edited by

Nowreen Haq

submission deadline 20 Feb 2026 | Viewed by 35 | Submission Open

Keywords: diabetes management; remote patient monitoring (RPM); artificial intelligence (AI); machine learning (ML); wearable sensors; point-of-care diagnostics; centrifugal microfluidics; glucose monitoring

(This special issue belongs to the Section Endocrinology & Metabolism)

Myocarditis and Pericarditis: Clinical Advances and Current Challenges

edited by

Ankit Agrawal

and

Tom Kai Ming Wang

submission deadline 20 Feb 2026 | Viewed by 34 | Submission Open

Keywords: pericarditis; myocarditis; pericardial effusion; cardiac tamponade; interleukin-1 inhibitors; pericardium

(This special issue belongs to the Section Cardiovascular Medicine)

Current Trends and Future Challenges in Percutaneous Coronary Intervention

edited by Deniz Mutlu

submission deadline 20 Feb 2026 | Viewed by 32 | Submission Open

Keywords: PCI; IVUS; OCT; FFR; physiology; CT-guided PCI; complex PCI; CTO; bifurcation; coronary complications; mechanical circulatory support

(This special issue belongs to the Section Cardiovascular Medicine)

Advances and Innovations in Radiology: From Contrast-Enhanced Mammography to Artificial Intelligence and Beyond

edited by

Luca Nicosia

submission deadline 20 Feb 2026 | Viewed by 32 | Submission Open

Keywords: contrast-enhanced mammography (CEM); artificial intelligence; radiomics; diagnostic imaging innovations; inter-ventional radiology

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Optimizing Rehabilitation in Kidney Disease

edited by Henry H. L. Wu and Rajkumar Chinnadurai

submission deadline 20 Feb 2026 | Viewed by 30 | Submission Open

Keywords: chronic kidney disease; renal rehabilitation; exercise intervention; nutrition; multidisciplinary; frailty; physical conditioning

(This special issue belongs to the Section Clinical Rehabilitation)

Minimally Invasive Surgery for Gastrointestinal Disorder

edited by

Amosy Ephreim M'Koma

submission deadline 20 Feb 2026 | Viewed by 30 | Submission Open

Keywords: minimally invasive surgery; gastrointestinal disorder; laparoscopy; robotic surgery; colorectal surgery; gastric surgery; endoscopic technique; oncological outcomes; surgical innovation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Updates on Acromegaly

edited by

Marek Bolanowski

, Jowita Halupczok-Żyła, Aleksandra Gilis-Januszewska and Przemysław Witek

submission deadline 20 Feb 2026 | Viewed by 29 | Submission Open

Keywords: acromegaly; GH; IGH-1; growth hormone-secreting pituitary adenoma; pituitary adenoma

(This special issue belongs to the Section Endocrinology & Metabolism)

Current Challenges and Innovations in Emergency Medicine: From Prehospital Care to Critical Decision-Making in the Emergency Department

edited by Efstratios Karagiannidis, Barbara P. Fyntanidou and Aikaterini Apostolopoulou

submission deadline 20 Feb 2026 | Viewed by 29 | Submission Open

Keywords: emergency medicine; prehospital care; triage strategies; acute care; point-of-care diagnostics; artificial intelligence; telemedicine; emergency department; patient flow; healthcare systems; burnout in emergency care

(This special issue belongs to the Section Emergency Medicine)

Age-Related Macular Degeneration: Challenges and Opportunities

edited by Deepayan Kar

submission deadline 20 Feb 2026 | Viewed by 28 | Submission Open

Keywords: age-related macular degeneration; imaging biomarkers; visual function testing; optical coherence tomography; anti-VEGF; complement; artificial intelligence

(This special issue belongs to the Section Ophthalmology)

Advances in the Diagnosis and Management of Atherosclerosis

edited by

Adrian Covic

and

Cristian Stătescu

submission deadline 20 Feb 2026 | Viewed by 27 | Submission Open

Keywords: atherosclerosis; cardiovascular disease; coronary artery disease; endothelial function; acute coronary syndromes

(This special issue belongs to the Section Cardiology)

Recent Advances in Gynecologic Surgery

edited by Adam Ostrzenski

submission deadline 20 Feb 2026 | Viewed by 25 | Submission Open

Keywords: gynecologic surgery; pelvic reconstruction surgery; female stress urinary incontinence surgery; cosmetic gynecology surgery; surgical meshes slings; native tissue

(This special issue belongs to the Section Obstetrics & Gynecology)

Maxillofacial Surgery in the Modern Era: Surgical Advances and Clinical Innovation

edited by

Jeremie Oliver Piña

submission deadline 20 Feb 2026 | Viewed by 25 | Submission Open

Keywords: maxillofacial surgery; oral surgery; craniofacial surgery; plastic surgery; bone

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Advances in Posttraumatic Stress Disorder (PTSD): Clinical Update

edited by An-Fu Hsiao and

Michael Hollifield

submission deadline 20 Feb 2026 | Viewed by 25 | Submission Open

Keywords: PTSD; stellate ganglion block; transcranial magnetic stimulations; neurobiology; trauma disorders; mind– body medicine; psychophysiology

(This special issue belongs to the Section Mental Health)

Traumatic Brain Injury—Clinical Translational Approaches, Demographic Change, and Neuro-Critical Care

edited by

Peter Radermacher

and Thomas Kapapa

submission deadline 20 Feb 2026 | Viewed by 24 | Submission Open

Keywords: intracranial hypertension; cerebral perfusion pressure; decompressive craniectomy; brain tissue oxygenation; brain tissue microdialysis; blood brain barrier; neuro-critical care

(This special issue belongs to the Section Brain Injury)

Clinical Insights in Cognitive Aging and Mild Cognitive Impairment

edited by

Irene Fernández

and

Laura Galiana

submission deadline 20 Feb 2026 | Viewed by 23 | Submission Open

Keywords: cognitive aging; mild cognitive impairment; normative aging; neuropsychological assessment; diagnosis; gerontology; prevention; intervention; multidisciplinary approach; measurement

(This special issue belongs to the Section Geriatric Medicine)

Recent Advances and Future Perspectives on Spinal Surgeries

edited by

Sung-kyu Kim

submission deadline 20 Feb 2026 | Viewed by 22 | Submission Open

Keywords: minimally invasive spine procedures; robotic-assisted spine surgery; image-guided navigation; spinal implants and biomaterials; artificial intelligence in spinal care; regenerative spine therapies; clinical outcomes in spine surgery; future trends in spinal interventions

(This special issue belongs to the Section Orthopedics)

Treatment and Long-Term Outcome of Fracture

edited by Corrado Ciatti,

Edoardo Bori

and Fabrizio Quattrini

submission deadline 20 Feb 2026 | Viewed by 21 | Submission Open

Keywords: traumatology; osteosynthesis; plating; nailing; osteosynthesis devices; surgical technique; approach

(This special issue belongs to the Section Orthopedics)

Displaying special issue 1251-1300 on page 26 of 28.

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