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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Innovations in Minimally Invasive and Personalized Urogynecology

edited by Günter Karl Noé and

Anna Pitsillidi

submission deadline 20 Nov 2026 | Viewed by 130 | Submission Open

Keywords: urogynecology; pelvic floor disorders; minimally invasive reconstructive techniques; personalized and regenerative treatment strategies

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Advancements in Radiology of Joint and Musculoskeletal Diseases

edited by

Gwendolyn Vuurberg

submission deadline 20 Nov 2026 | Viewed by 130 | Submission Open

Keywords: sports injuries; ligament injuries; ankle injury; prognostic imaging; individualized imaging; imaging algorithms; lower-extremity injury; clinical insights; knee injuries; groin and hip pain

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Advances in Adult Congenital Heart Disease: From Diagnosis to Long-Term Management

edited by Michael Huntgeburth

submission deadline 20 Nov 2026 | Viewed by 129 | Submission Open

Keywords: adult congenital heart disease; ACHD; long-term management; lifetime management; complications; arrhythmia; heart failure; endocarditis; pulmonary arterial hypertension; comorbidities; interventional treatment; surgical treatment; rehabilitation

(This special issue belongs to the Section Cardiology)

Obesity and the Airway: Disease Mechanisms, Associated Conditions, and Management

edited by

Mohamad R. Chaaban

submission deadline 20 Nov 2026 | Viewed by 126 | Submission Open

Keywords: obesity; airway; inflammation; rhinosinusitis; cerebrospinal fluid leak; asthma; chronic obstructive pulmonary disease; sleep; obstructive sleep apnea; intubation; laryngopharyngeal reflux; laryngotracheal stenosis

(This special issue belongs to the Section Respiratory Medicine)

New Technological Treatments and Methods in Neurorehabilitation

edited by

József Tollár

submission deadline 20 Nov 2026 | Viewed by 126 | Submission Open

Keywords: neurorehabilitation; robotics; virtual reality; exoskeleton; humankinesiology physiotherapy; stroke; parkinson's disease; gait; physical rehabilitation; rehabilitation interventions

(This special issue belongs to the Section Clinical Neurology)

Towards an Improved Understanding of Alzheimer's and Related Dementias: Interdisciplinary and Clinical Progress

edited by

Juan Rodríguez-Mansilla

Blanca Gonzalez-Sanchez

and

María Jiménez-Palomares

submission deadline 20 Nov 2026 | Viewed by 125 | Submission Open

Keywords: Alzheimer’ s disease; related dementias; neurodegeneration; biomarkers; neuroimaging; early diagnosis; cognitive decline; clinical management; therapeutic interventions; psychosocial care; risk factors; dementia prevention

(This special issue belongs to the Section Clinical Neurology)

Current Concepts of Cardio–Renal Interactions

edited by

Yacov Shacham

submission deadline 20 Nov 2026 | Viewed by 125 | Submission Open

Keywords: AKI; cardiorenal syndrome; contrast; biomarkers; renal insufficiency; cardio-nephrology; organ crosstalk

(This special issue belongs to the Section Cardiovascular Medicine)

Advances and Challenges in the Diagnosis and Treatment of Epilepsy

edited by

Elena Pasini

submission deadline 20 Nov 2026 | Viewed by 125 | Submission Open

Keywords: epilepsy; diagnosis; treatment; epilepsy surgery; clinical management

(This special issue belongs to the Section Clinical Neurology)

Optimizing Catheter Ablation for Atrial Fibrillation: Emerging Technologies and Clinical Progress

edited by Naiara Calvo

submission deadline 20 Nov 2026 | Viewed by 124 | Submission Open

Keywords: atrial fibrillation; pulsed field ablation; electroanatomical mapping; catheter ablation; electroporation; pulmonary veins

(This special issue belongs to the Section Cardiology)

Fertility and Reproductive Health in Women

edited by

Stylianos Vagios

submission deadline 20 Nov 2026 | Viewed by 121 | Submission Open

Keywords: female fertility; reproductive health; infertility; assisted reproductive technology; reproductive endocrinology; ovarian reserve; reproductive aging; PCOS; endometriosis; fertility preservation

(This special issue belongs to the Section Obstetrics & Gynecology)

Periodontal Diseases: Latest Advances in Diagnosis and Therapeutic Strategies

edited by Francesco Saverio Martelli and Giada Marroncini

submission deadline 20 Nov 2026 | Viewed by 121 | Submission Open

Keywords: periodontal diseases; precision dentistry; genetic susceptibility; oral microbiome; inflammatory biomarkers; personalized therapy; multidisciplinary approach; periodontal diagnostics; host response modulation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

From the Silk Road of Endoscopy to the Roads to Rome V of Neurogastroenterology: Dual Pathways Shaping Modern Gastroenterology

edited by Stefano Kayali

submission deadline 20 Nov 2026 | Viewed by 117 | Submission Open

Keywords: endoscopy; advanced imaging; minimally invasive therapies; gastrointestinal diagnostics; gut– brain interaction; DGBI; Rome V; neurogastroenterology; clinical innovation; GI physiology

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Genitourinary Infections: Current Status and Emerging Challenges

edited by

Stavroula Baka

and George I. Kaparos

submission deadline 20 Nov 2026 | Viewed by 112 | Submission Open

Keywords: genital tract infections; sexually transmitted infections; vaginal infections; urinary tract infections; recurrent infections; diagnostic challenges; antimicrobial resistance

(This special issue belongs to the Section Infectious Diseases)

Practical Use of Technologies in Neuro-Oncological Surgery Across Different Settings

edited by Davide Milani

submission deadline 20 Nov 2026 | Viewed by 109 | Submission Open

Keywords: neuro-oncology; surgical technology; neuronavigation; intraoperative ultrasound; fluorescence-guided surgery; augmented reality; artificial intelligence; surgical innovation; clinical practice

(This special issue belongs to the Section Clinical Neurology)

Paediatric Thyroid Cancer: Diagnosis and Therapeutic Strategies

edited by Paul Z. Benitez-Aguirre,

Andrew J. Bauer

, Antoinette Anazodo and Theodore W. Laetsch

submission deadline 20 Nov 2026 | Viewed by 108 | Submission Open

Keywords: paediatric thyroid cancer; differentiated thyroid carcinoma; molecular diagnostics; gene fusions (RET; NTRK; BRAF); targeted therapy; neoadjuvant therapy; adjuvant therapy; radioactive iodine (131I); dosimetry; tumour response and shrinkage; multidisciplinary models of care; survivorship and late effects

(This special issue belongs to the Section Endocrinology & Metabolism)

Latest Advances and Prospects in Urogynecology and Pelvic Floor Surgery

edited by

Ewa Monika Barcz

submission deadline 20 Nov 2026 | Viewed by 108 | Submission Open

Keywords: urogynecology; pelvic floor disorders; pelvic organ prolapse; urinary incontinence; fecal incontinence; minimally invasive surgery; pelvic floor imaging; vaginal surgery; pelvic pain syndrome

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Advances in Immune-Mediated Inflammatory Diseases

edited by

Lovro Lamot

submission deadline 20 Nov 2026 | Viewed by 107 | Submission Open

Keywords: pediatric immune-mediated inflammatory diseases (IMIDs); juvenile idiopathic arthritis; systemic lupus erythematosus; pediatric vasculitis; IgA nephropathy; complement-mediated kidney diseases; inflammatory bowel diseases; organ-specific inflammation; biomarkers for disease activity and diagnosis; biologic and targeted therapies; early recognition and diagnostic strategies; multidisciplinary care and integrated management

(This special issue belongs to the Section Immunology & Rheumatology)

Artificial Intelligence Applications in Urology

edited by

Francesco Prata

, Rocco Papalia and Nicolas Carl

submission deadline 20 Nov 2026 | Viewed by 106 | Submission Open

Keywords: artificial intelligence; urology; machine learning; robotic surgery; digital pathology; predictive modeling

(This special issue belongs to the Section Nephrology & Urology)

Psychological Safety: Bodily and Psychological Determinants in Clinical Settings

edited by

Andrea Poli

and Stephen W. Porges

submission deadline 20 Nov 2026 | Viewed by 105 | Submission Open

Keywords: psychological safety; fear; psychological trauma; shame; dissociation; neuroception; trust; polyvagal theory

(This special issue belongs to the Section Mental Health)

Interventional Pulmonology: Advances and Future Directions—2nd Edition

edited by Martina Ferioli and Piero Candoli

submission deadline 20 Nov 2026 | Viewed by 104 | Submission Open

Keywords: interventional pulmonology; lung nodule; lung cancer; diagnosis; bronchoscopy; rigid bronchoscopy; airway stent; airway stenosis; mediastinal staging

(This special issue belongs to the Section Respiratory Medicine)

Sexually Transmitted Infections: Persistent Challenges and Innovative Solutions

edited by Thomas E. Dobbs and

Mauda L. Monger

submission deadline 20 Nov 2026 | Viewed by 103 | Submission Open

Keywords: sexually transmitted infections (STIs); sexual and reproductive health; STI prevention and control; public health interventions; prevention advancements in sexual health; stigma and sexual health

(This special issue belongs to the Section Infectious Diseases)

Prostate Cancer: Clinical Advances and Prognosis Now and in the Near Future

edited by Josip Španjol

submission deadline 20 Nov 2026 | Viewed by 87 | Submission Open

Keywords: prostate cancer; immunotherapy; clinical trials; personalized medicine; artificial intelligence; robotic surgery; radical prostatectomy; radiotherapy

(This special issue belongs to the Section Nephrology & Urology)

Advances in Fetal Medicine: AI Integration and Advancements

edited by Christos Anthoulakis

submission deadline 20 Nov 2026 | Viewed by 75 | Submission Open

Keywords: fetal medicine; artificial intelligence; obstetrical complications; fetal syndromes; genetic conditions

(This special issue belongs to the Section Obstetrics & Gynecology)

Interventional Pain Management: Current Evidence and Innovative Advances

edited by Jamal Hasoon

submission deadline 24 Nov 2026 | 1 articles | Viewed by 310 | Submission Open

Keywords: interventional pain management; chronic pain; image-guided procedures; injection techniques; neuromodulation; peripheral nerve blocks; radiofrequency ablation; minimally invasive spine interventions; artificial intelligence in medicine; quality improvement; clinical outcomes

(This special issue belongs to the Section Anesthesiology)

The Management of Chronic Cholestatic Diseases

edited by

Maria Consiglia Bragazzi

submission deadline 24 Nov 2026 | Viewed by 161 | Submission Open

Keywords: chronic cholestatic liver diseases; cholestasis; primary biliary cholangitis; primary sclerosing cholangitis; cholangiocar-cinoma

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in the Diagnosis and Treatment of Glaucoma

edited by

Alessio Martucci

submission deadline 25 Nov 2026 | 11 articles | Viewed by 13820 | Submission Open

Keywords: OCT; glaucoma; MIGS; neuroprotection; drug delivery systems; artificial intelligence; pharmacologic agents; per-sonalized medicine

(This special issue belongs to the Section Ophthalmology)

Diabetic Foot: Emerging Prevention Strategies and Epidemiology

edited by

Vilma Urbančič-Rovan

submission deadline 25 Nov 2026 | 3 articles | Viewed by 4146 | Submission Open

Keywords: diabetic foot; foot clinics; epidemiology; prevention; screening; amputation; podiatry

(This special issue belongs to the Section Endocrinology & Metabolism)

Current Clinical Advances in Urinary Incontinence

edited by Adolf Lukanovic, David Lukanović and Mija Blaganje

submission deadline 25 Nov 2026 | 3 articles | Viewed by 3993 | Submission Open

Keywords: female urinary incontinence; stress urinary incontinence; overactive bladder; diagnosis; prevention; conservative treatment; minimally invasive treatment; surgery; mid-urethral sling; new approach; energy-based devices

(This special issue belongs to the Section Nephrology & Urology)

Approaches and Challenges in Oral Rehabilitation

edited by

Yoko Hasegawa

and Takayuki Kosaka

submission deadline 25 Nov 2026 | 2 articles | Viewed by 2539 | Submission Open

Keywords: oral rehabilitation; oral health; systemic health; dental innovation; neuroplasticity

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Advances in Personalized Psychiatry

edited by

Rosaria Di Lorenzo

submission deadline 25 Nov 2026 | 2 articles | Viewed by 1232 | Submission Open

Keywords: personalized psychiatry; biomarkers; predictive modeling; precision diagnosis; neuroimaging biomarkers; effective treatments

(This special issue belongs to the Section Mental Health)

Epilepsy and Cerebrovascular Disorders

edited by

Leonardo Roever

submission deadline 25 Nov 2026 | 1 articles | Viewed by 887 | Submission Open

Keywords: epilepsy; cerebrovascular disorders; stroke; post-stroke epilepsy; neuroinflammation; neuroimaging; electroenceph-alography; biomarkers; antiepileptic treatment; translational neuroscience

(This special issue belongs to the Section Clinical Neurology)

Surgical Innovation and Clinical Outcomes in Plastic and Reconstructive Surgery

edited by Pari Naz Mohanna and Ayush Kapila

submission deadline 25 Nov 2026 | 1 articles | Viewed by 789 | Submission Open

Keywords: plastic and reconstructive surgery; microsurgery; breast reconstruction; surgical innovation; novel flap techniques

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Physical Activity, Exercise and Health: Implications for Clinical Practice

edited by

Nuria Marín-Jiménez

submission deadline 25 Nov 2026 | 1 articles | Viewed by 787 | Submission Open

Keywords: physical activity; exercise prescription; clinical practice; chronic disease management; rehabilitation; preventive medicine; personalized medicine; sex and gender differences

(This special issue belongs to the Section Sports Medicine)

Advances in Kidney Transplantation: 2nd Edition

edited by Pedro Ruiz-Esteban, Domingo Hernández-Marrero and Verónica López-Jiménez

submission deadline 25 Nov 2026 | 1 articles | Viewed by 757 | Submission Open

Keywords: kidney transplant; acute rejection; biomarkers; artificial intelligence; post-transplant complications; graft survival

(This special issue belongs to the Section Nephrology & Urology)

The Current Concept and Emerging Treatments of Coronary Artery Disease (CAD)

edited by Simone Fezzi and Roberto Scarsini

submission deadline 25 Nov 2026 | 1 articles | Viewed by 632 | Submission Open

Keywords: coronary physiology; intracoronary imaging; imaging-derived computational physiology; drug-coated balloon and bioresorbable scaffolds; virtual PCI; artificial intelligence

(This special issue belongs to the Section Cardiovascular Medicine)

Latest Clinical Advances in Refractive Surgery

edited by

Francesco D'Oria

and Giovanni Alessio

submission deadline 25 Nov 2026 | 1 articles | Viewed by 516 | Submission Open

Keywords: refractive surgery; corneal surgery; complications; innovative surgical techniques; diagnostic technologies

(This special issue belongs to the Section Ophthalmology)

Recent Advances in Minimally Invasive Surgery and Endoscopy of Gynecologic Oncology

edited by Hiroaki Komatsu,

Eiji Kondo

and Tsukasa Baba

submission deadline 25 Nov 2026 | 1 articles | Viewed by 490 | Submission Open

Keywords: cervical cancer; ovarian cancer; gynecologic cancer; robotic surgery; minimally invasive surgery

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Advances and Challenges in Vascular and Endovascular Medicine: 2nd Edition

edited by

Luca Bertoglio

submission deadline 25 Nov 2026 | 1 articles | Viewed by 481 | Submission Open

Keywords: vascular and endovascular medicine; minimally invasive cardiovascular surgery; vascular diseases; endovascular technologies

(This special issue belongs to the Section Vascular Medicine)

Therapeutic Strategies in Rheumatic Diseases

edited by Răzvan Gabriel Drăgoi

submission deadline 25 Nov 2026 | 1 articles | Viewed by 467 | Submission Open

Keywords: rheumatic diseases; innovation; therapeutics; multidisciplinary; patient centered

(This special issue belongs to the Section Immunology & Rheumatology)

Tinnitus: Clinical Updates from Diagnosis to Treatment

edited by

Chul Ho Jang

submission deadline 25 Nov 2026 | Viewed by 395 | Submission Open

Keywords: tinnitus related research; drug; cochlear implant or middle ear implant related tinnitus reduction

(This special issue belongs to the Section Otolaryngology)

Spinal Cord Injury: New Horizons in Neurorehabilitation and Clinical Management

edited by Andrew Kerr and

Sintip Pattanakuhar

submission deadline 25 Nov 2026 | Viewed by 199 | Submission Open

Keywords: spinal cord injury; rehabilitation; neuroplasticity; secondary health condition; neurological recovery; functional recovery; neuroprotection; neuroregeneration; neurotechnology

(This special issue belongs to the Section Clinical Neurology)

Hematological Neoplasms: Diagnosis, Treatment, and Management in the Department of Veterans Affairs

edited by Solomon A. Graf, Daphne R. Friedman and Suman Kambhampati

submission deadline 25 Nov 2026 | Viewed by 199 | Submission Open

Keywords: hematologic malignancies; veterans affairs; therapeutics; biomarkers; rural medicine; integrated healthcare; demographics; exposures; trials in progress; treatment pathways

(This special issue belongs to the Section Hematology)

Clinical Progress in Diagnosis and Treatment of Pancreatic Cancer

edited by

Patrick Kirchweger

, Helwig Valentin Wundsam and

Reinhold Függer

submission deadline 25 Nov 2026 | Viewed by 160 | Submission Open

Keywords: pancreatic ductal adenocarcinoma; early detection and biomarkers; multidisciplinary treatment strategies; complication management; liquid biopsy; surgical outcomes; translational clinical research

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Novel Approaches and Techniques in Neurosurgery

edited by

Ismail Zaed

and

Mario Ganau

submission deadline 25 Nov 2026 | Viewed by 158 | Submission Open

Keywords: neurosurgery; minimally invasive neurosurgery; endoscopic neurosurgery; spine surgery; surgical robotics; neu-ro-navigation; intraoperative imaging; artificial intelligence; neuro-oncology surgery; skull base surgery; im-age-guided surgery

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances and Emerging Trends in Metabolic Bariatric Surgery

edited by

Andrew G.N. Robertson

submission deadline 25 Nov 2026 | Viewed by 153 | Submission Open

Keywords: metabolic bariatric surgery; bariatric endoscopy; robotic assisted surgery; obesity management medications; bariatric surgery

(This special issue belongs to the Section General Surgery)

Emerging Insights into Critical Care

edited by Shunsuke Takaki

submission deadline 25 Nov 2026 | Viewed by 153 | Submission Open

Keywords: critical care; intensive care unit; post-cardiac surgery; mechanical ventilation; clinical deterioration prediction; machine learning

(This special issue belongs to the Section Intensive Care)

Clinical Advances in Hypertension and Its Related Complications

edited by Antonio Concistrè

submission deadline 25 Nov 2026 | Viewed by 150 | Submission Open

Keywords: hypertension; secondary hypertension; resistant hypertension; blood pressure monitoring; target organ damage; cardiovascular risk; antihypertensive therapy; hypertension in pregnancy

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Applications of Ultrasound and Advanced Imaging Techniques in Thyroid Diseases

edited by

Dana Stoian

and Andreea Bena

submission deadline 25 Nov 2026 | Viewed by 147 | Submission Open

Keywords: thyroid neoplasms; ultrasonography; elasticity imaging techniques; contrast media; thyroid MPUS; risk assessment; thyroid nodules; autoimmune thyroid disease

(This special issue belongs to the Section Endocrinology & Metabolism)

Innovations in Lumbar Spinal Surgery: Techniques, Outcomes, and Future Directions

edited by Shane Shahrestani and Andy Ton

submission deadline 25 Nov 2026 | Viewed by 135 | Submission Open

Keywords: lumbar spinal surgery; minimally invasive techniques; robotic-assisted surgery; spinal fusion; spinal implants

(This special issue belongs to the Section Orthopedics)

Clinical Management of Female Pelvic Floor Disorders

edited by

Andrea Braga

and Stefano Salvatore

submission deadline 25 Nov 2026 | Viewed by 133 | Submission Open

Keywords: urinary incontinence; pelvic organ prolapse; pelvic floor disorders; pelvic reconstructive surgery; anal incontinence

(This special issue belongs to the Section Obstetrics & Gynecology)

Displaying special issue 1251-1300 on page 26 of 31.

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