Cardiomyopathies: A Contemporary Review of Advances and Clinical Strategies

Dear Colleagues,

Cardiomyopathies represent a heterogeneous group of myocardial disorders with diverse etiologies, pathophysiological mechanisms, and clinical manifestations. They remain a major cause of heart failure, arrhythmias, and sudden cardiac death worldwide, posing substantial diagnostic and therapeutic challenges. Over the last decade, there has been remarkable progress in understanding their genetic basis, molecular pathways, and phenotypic spectrum, as well as in developing novel diagnostic and therapeutic strategies.

This Special Issue, “Cardiomyopathies: A Contemporary Review of Advances and Clinical Strategies,” aims to provide a comprehensive overview of recent breakthroughs and emerging concepts in the field of cardiomyopathies. We welcome original research articles, state-of-the-art reviews, and meta-analyses that address both fundamental and clinical aspects of these complex disorders. Topics of interest include, but are not limited to, the following:

• Advances in genetic and molecular characterization of cardiomyopathies;
• Novel imaging techniques for early detection, risk stratification, and disease monitoring;
• Pathophysiology and clinical management of dilated, hypertrophic, restrictive, arrhythmogenic, and inflammatory cardiomyopathies;
• The role of precision medicine, targeted therapies, and gene-based interventions;
• Contemporary strategies in arrhythmia prevention and sudden cardiac death risk reduction;
• Integration of multimodality imaging, biomarkers, and artificial intelligence for personalized care.

By gathering multidisciplinary expertise, this Special Issue seeks to highlight current challenges and future directions in the diagnosis and management of cardiomyopathies, fostering translation from bench to bedside and ultimately improving patient outcomes.

We warmly invite you to contribute your valuable work to this Special Issue and look forward to receiving your submissions.

Dr. Carla Contaldi
Guest Editor

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