Novel Insights into the Prevention and Treatment of Contact Dermatitis

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dermatology".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 835

Special Issue Editors

German Social Accident Insurance for the Health and Welfare Services, Department of Occupational Medicine, Hazardous Substances and Health Sciences, Division of Occupational Medicine, 20357 Hamburg, Germany
Interests: occupational medicine; occupational dermatology; preventive medicine; health education; skin bioengineering

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Guest Editor
Institute for Interdisciplinary Dermatological Prevention and Rehabilitation (iDerm), Osnabrück University, 49076 Osnabrück, Germany
Interests: occupational and environmental dermatology; allergology; nutritional medicine

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Guest Editor
Department of Dermatology, Environmental Medicine and Health Theory, Institute for Health Research and Education (IGB), Faculty of Human Sciences, Osnabrück University, 49076 Osnabrück, Germany
Interests: occupational and environmental dermatology; allergology; immunology

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Guest Editor
1. German Social Accident Insurance for the Health and Welfare Services, Department of Occupational Medicine, Hazardous Substances and Health Sciences, Division of Occupational Medicine, 20357 Hamburg, Germany
2. Centre of Excellence for Epidemiology and Health Services Research for Healthcare Professionals (CVcare), 20246 Hamburg, Germany
Interests: preventive medicine; psychosocial medicine; healthcare research
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Special Issue Information

Dear Colleagues,

We are pleased to invite you to contribute to this Special Issue, “Novel Insights into the Prevention and Treatment of Contact Dermatitis”. Contact dermatitis is defined as localized inflammation caused by skin contact with an external factor (e.g., physical or chemical). As a multifactorial disease, individual susceptibility, as well as environmental and occupational factors, play a role in the genesis of contact dermatitis. It can broadly be grouped into irritant and allergic forms, with mixed types being frequent. Contact dermatitis does not only result in a high disease burden for the individuals affected but also a high burden for society in terms of medical costs. Thus, it is of high importance to—at best—prevent contact dermatitis and treat cases by utilizing adequate therapeutic measures.

This Special Issue aims to gather recent developments and achievements in the field of contact dermatitis. Herein, dermatitis will not only be considered in the private sphere but also in the occupational setting. In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • Irritant contact dermatitis;
  • Allergic contact dermatitis;
  • Occupational contact dermatitis;
  • The time trends of contact dermatitis as an occupational disease;
  • Contact dermatitis of the hands/hand eczema;
  • Diagnostics of contact dermatitis;
  • Prevention of contact dermatitis ;
  • Therapy for contact dermatitis;
  • Health education and contact dermatitis;
  • Health psychology and contact dermatitis;
  • Disease burden of contact dermatitis;
  • Skin bioengineering/epidermal barrier function and contact dermatitis.

We look forward to receiving your contributions.

With best wishes,

Dr. Cara Bieck
Prof. Dr. Christoph Skudlik
Prof. Dr. Swen Malte John
Prof. Dr. Albert Nienhaus
Guest Editors

Manuscript Submission Information

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Keywords

  • allergic
  • allergy
  • contact dermatitis
  • irritant
  • occupation
  • prevention
  • sensitization
  • skin
  • therapy
  • treatment

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Published Papers (1 paper)

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Research

11 pages, 1211 KiB  
Article
Clinical Characteristics and Patch Test Results in 57 Patients with Contact Dermatitis in Southern Taiwan
by Shang-Hung Lin and Yin-Cheng Chao
J. Clin. Med. 2025, 14(7), 2291; https://doi.org/10.3390/jcm14072291 - 27 Mar 2025
Viewed by 553
Abstract
Background/Objectives: Patch testing is a valuable clinical tool for identifying the causes of allergic contact dermatitis (ACD). This study aimed to identify common allergens in southern Taiwan. Methods: A retrospective review of patch test data from April 2019 to May 2023 [...] Read more.
Background/Objectives: Patch testing is a valuable clinical tool for identifying the causes of allergic contact dermatitis (ACD). This study aimed to identify common allergens in southern Taiwan. Methods: A retrospective review of patch test data from April 2019 to May 2023 was conducted at a tertiary medical center. The European Baseline Series of allergens was utilized to evaluate and identify the causes of dermatitis. The prevalence rates of contact sensitization to each allergen were calculated. Results: A total of 57 patients (mean age 41.8 years) with contact dermatitis who underwent patch testing were included. The most common allergens were cobalt chloride (24.6%), followed by fragrance mix I (19.3%), Peru balsam (17.5%), nickel (II) sulfate hexahydrate (15.8%), benzisothiazolinone (15.8%), 4-Phenylenediamine (PPD) base (10.5%), and methyldibromo glutaronitrile (10.5%). Patients with positive patch test results frequently had a history of allergic rhinitis (26.3%), atopic dermatitis (24.6%), urticaria (21.1%), and elevated immunoglobulin E (IgE) levels (28.1%). The hairdressing profession was associated with a higher risk of hand eczematous dermatitis. Conclusions: Positive patch test results were observed in 86% of patients diagnosed with contact dermatitis. This study found that cobalt, rather than nickel, was the most prevalent allergen in patients with contact dermatitis. Elevated IgE levels were observed in ACD patients, with the hands being the most frequently affected area. Occupations as accountants, secretaries, and in the hairdressing and cosmetics industries were strongly associated with hand eczematous dermatitis. The early identification of allergens and appropriate treatment strategies significantly reduced recurrence rates and improved outcomes. For individuals with specific allergies, ongoing avoidance of identified allergens is crucial to managing and preventing allergic reactions. Further research is needed to elucidate the mechanisms and responses to novel therapies, including biologic agent- and nanotechnology-based treatments. Full article
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