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Clinical Updates on Perioperative Pain Management: 3rd Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Anesthesiology".

Deadline for manuscript submissions: 20 May 2026 | Viewed by 151

Special Issue Editors


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Guest Editor
Anesthesia, Intensive Care and Pain Management, Fondazione Policlinico Universitario, Campus Bio-Medico, Rome, Italy
Interests: anesthesia; airway management; difficult airway; mechanical ventilation; extra-glottic airway devices; resuscitation; analgesia; pain management; regional anesthesia; neuromuscular monitoring; COVID-19; fluid therapy
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Anesthesia, Intensive Care and Pain Management, Fondazione Policlinico Universitario, Campus Bio-Medico, Rome, Italy
Interests: anesthesia and intensive care; airway management; regional anesthesia; analgesia; pain management; postoperative pain; knee replacement arthroplasties; breast surgery; thoracotomy; orthopedic surgery; hip surgery; ultrasound
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Anesthesia, Intensive Care and Pain Management, Fondazione Policlinico Universitario, Campus Bio-Medico, Rome, Italy
Interests: anesthesia and intensive care; pain management; regional anesthesia; analgesia; postoperative pain; knee replacement arthroplasties; breast surgery; thoracotomy; orthopedic surgery; hip surgery; ultrasound
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

It is my pleasure to invite you to contribute to this Special Issue entitled “Clinical Updates on Perioperative Pain Management: 3rd Edition”. In the previous volume of this Special Issue, we published eight papers. For more details, please visit:

https://www.mdpi.com/journal/jcm/special_issues/CYPQG79OA8

Pain is a personal experience that is influenced to varying degrees by biological, psychological, and social factors. Optimal perioperative pain management positively impacts the quality of patients’ recovery, reducing the incidence of complications.

For this reason, multimodal approaches such as regional anesthesia techniques, analgesics drugs, and rehabilitation programs play a key role in the field, with research aiming to improve perioperative analgesia. This Special Issue welcomes the submission of original high-quality articles that address the use of innovative regional anesthesia techniques, such as neuraxial blocks, peripheral nerve blocks, and fascial plane blocks, in the treatment of perioperative pain. Moreover, we welcome the submission of papers that investigate the use of specific drugs, rehabilitation protocols, or innovative devices to manage perioperative analgesia. Contributions may be in the form of research papers, original studies, or reviews.

Prof. Dr. Felice Eugenio Agro
Dr. Giuseppe Pascarella
Dr. Fabio Costa
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • anesthesia and intensive care
  • pain management
  • spinal anesthesia
  • postoperative pain
  • breast surgery
  • fascial plane blocks
  • abdominal surgery
  • cardiac surgery
  • thoracotomy
  • knee surgery
  • orthopedic surgery
  • hip surgery
  • ultrasound

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Published Papers (1 paper)

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Research

12 pages, 867 KB  
Article
Analysis of Factors Affecting Postoperative Opioid Requirement in Adult Patients Undergoing Minimally Invasive Repair of Pectus Excavatum
by Minju Kim, Saewon Park, Seung Keun Yoon and Wonjung Hwang
J. Clin. Med. 2026, 15(3), 1023; https://doi.org/10.3390/jcm15031023 - 27 Jan 2026
Abstract
Background/Objectives: Minimally invasive repair of pectus excavatum (MIRPE) is an established surgical treatment for adult pectus excavatum (PE). Compared with pediatric patients, adults generally have a more rigid chest wall and greater costal cartilage ossification, often resulting in more severe postoperative pain. [...] Read more.
Background/Objectives: Minimally invasive repair of pectus excavatum (MIRPE) is an established surgical treatment for adult pectus excavatum (PE). Compared with pediatric patients, adults generally have a more rigid chest wall and greater costal cartilage ossification, often resulting in more severe postoperative pain. However, most previous studies have focused on pediatric patients with PE and on evaluating effective analgesic methods. This study aimed to investigate perioperative factors associated with postoperative opioid requirements and pain intensity in adult patients undergoing MIRPE. Methods: This study was a single-center retrospective study of adult PE patients who underwent MIRPE between March 2011 and January 2023. The primary outcome was total opioid consumption during the first 24 postoperative hours. Secondary outcomes included opioid and rescue analgesic use within 0–6, 6–24, and 24–48 h, as well as pain intensity during each interval. Multivariable linear regression analysis was performed to identify factors associated with postoperative opioid consumption. Results: A total of 382 patients were analyzed. Pain intensity peaked within the first 6 postoperative hours, decreased during the 6–24 h and increased during 24–48 h period. Higher BMI and placement of more than three bars were independently associated with greater opioid consumption during the first 6 h (p < 0.001). Within 24 and 48 h, male sex, longer operation time and higher BMI were independently associated with opioid consumption (p < 0.001). During 6–24 and 24–48 h period, VAS severity was significantly higher in male patients and those with longer operation times. Conclusions: Male sex, higher BMI, prolonged operation time, and multiple bar insertion may contribute to greater postoperative opioid requirements during the early postoperative phase in adult patients undergoing MIRPE. Full article
(This article belongs to the Special Issue Clinical Updates on Perioperative Pain Management: 3rd Edition)
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