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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Concepts in Diagnostic and Surgical HPB Technology
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 589 | Submission Open
Keywords: HPB surgery; minimal invasive approach; imaging; artificial intelligence; robotic surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Current Understanding and Management of Asthma and Chronic Obstructive Pulmonary Disease
edited by Josuel Ora
submission deadline 20 Nov 2026 | 2 articles | Viewed by 549 | Submission Open
Keywords: asthma; chronic obstructive pulmonary disease (COPD); personalized medicine; exacerbations; biomarkers; inhalation therapy; digital health; artificial intelligence; pulmonary rehabilitation; comorbidities
(This special issue belongs to the Section Respiratory Medicine)
Clinical Updates on Oral Health and Dental Care
edited by Wojciech Niemczyk and Rafał Wiench
submission deadline 20 Nov 2026 | 1 articles | Viewed by 523 | Submission Open
Keywords: oral health management; dental care; oral inflammatory diseases; oral diseases; preventive dentistry; periodontitis; oral medicine; clinical dentistry; dental surgery; periodontology
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Innovations in the Treatment for Depression and Anxiety—2nd Edition
edited by Lucie Bartova
submission deadline 20 Nov 2026 | 2 articles | Viewed by 438 | Submission Open
Keywords: depression; anxiety; antidepressant; anxiolytic; psychopharmacotherapy; psychotherapy; brain stimulation; treatment; response; resistance
(This special issue belongs to the Section Mental Health)
Digital Mental Health and Artificial Intelligence: Clinical Perspectives and Patient Safety
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 436 | Submission Open
Keywords: mental health care; telepsychiatry; telepsychotherapy; patient safety; health care data; clinical practice; digital mental health interventions; artificial intelligence in psychiatry; digital trust human– robot interactions; social networks
(This special issue belongs to the Section Mental Health)
Advances in Thoracic Surgery: Minimally Invasive Techniques, Precision Lung Resection, and Emerging Technologies
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 433 | Submission Open
Keywords: minimally invasive thoracic surgery; robotic-assisted thoracic surgery (RATS); video-assisted thoracic surgery (VATS); precision lung resection; lung cancer surgery; segmentectomy; 3D imaging and surgical planning; extra-corporeal lung support
(This special issue belongs to the Section General Surgery)
The Latest Advancements in Solid Organ Transplantation
edited by Eviatar Nesher
submission deadline 20 Nov 2026 | 1 articles | Viewed by 430 | Submission Open
Keywords: solid organ transplantation; robotic transplant surgery; living donor transplantation; indocyanine green fluorescence imaging; delayed graft function; mixed chimerism; tolerance induction; bone marrow transplantation; islet autotransplantation; total pancreatectomy; artificial intelligence; machine learning; kidney transplantation; liver transplantation; immunosuppression
(This special issue belongs to the Section General Surgery)
Clinical Updates on Cardiac Arrhythmias submission deadline 20 Nov 2026 | 1 articles | Viewed by 413 | Submission Open
Keywords: clinical electrophysiology; inherited arrhythmia syndromes; arrhythmias in structural heart disease; catheter ablation; device-based therapy
(This special issue belongs to the Section Cardiology)
Clinical Advances in HPV-Related Disease submission deadline 20 Nov 2026 | 1 articles | Viewed by 405 | Submission Open
Keywords: gynecological cancers; HPV; HPV vaccine; cervical cancer; precancerous lesions diagnostics
(This special issue belongs to the Section Obstetrics & Gynecology)
Heart Valve Surgery: Challenges and Advances in Conventional Surgery and Transcatheter Valve Therapy
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 358 | Submission Open
Keywords: mitral valve surgery; aortic valve surgery; tricuspid valve surgery; ross procedure; david procedure; transcatheter valve therapy; homograft valve replacement; infective endocarditis surgery
(This special issue belongs to the Section Cardiology)
The Use of Circulating Extracellular Vesicles as a Tool in the Diagnosis, Monitoring and Treatment of Disease submission deadline 20 Nov 2026 | Viewed by 320 | Submission Open
Keywords: circulating extracellular vesicles; regenerative medicine; biomarker; diagnosis; exosomes; liquid biopsy
(This special issue belongs to the Section Clinical Laboratory Medicine)
Quality of Life in Patients with Gynecological Cancers
edited by , and Monika Englert-Golon
submission deadline 20 Nov 2026 | Viewed by 297 | Submission Open
Keywords: quality of life; gynecology oncology; ovarian cancer; breast cancer; cervical cancer; endometrial cancer; women; gynecological diseases; oncological diseases
(This special issue belongs to the Section Obstetrics & Gynecology)
New Updates in Kidney Cancer submission deadline 20 Nov 2026 | Viewed by 289 | Submission Open
Keywords: renal cell carcinoma (RCC); robot-assisted partial nephrectomy (RAPN); artificial intelligence in oncology; cryoablation; kidney cancer management
(This special issue belongs to the Section Nephrology & Urology)
Oral and Maxillofacial Surgery: Current Progress and Future Directions submission deadline 20 Nov 2026 | Viewed by 241 | Submission Open
Keywords: oral and maxillofacial surgery; digital planning; head and neck surgery; reconstructive surgery; implant– prosthetic rehabilitation; oral diseases; regenerative dentistry; AI
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Myocardial Infarction: The Latest Advances and Prospects
edited by and Antonios Ziakas
submission deadline 20 Nov 2026 | Viewed by 229 | Submission Open
Keywords: coronary artery disease; myocardial infarction; PPCI; echocardiography; antiplatelet agents; radial access; global longitudinal strain
(This special issue belongs to the Section Cardiology)
Advances in the Management of Cancer Pain
edited by Wojciech Leppert
submission deadline 20 Nov 2026 | Viewed by 193 | Submission Open
Keywords: analgesia; analgesics; cancer patients; chronic pain; pain in cancer patients; pain assessment; non-opioids; opioid analgesics; adjuvant analgesics; non-pharmacology methods of pain management
(This special issue belongs to the Section Epidemiology & Public Health)
Innovative Neurosurgery: Scientific Breakthroughs and Modern Practice
edited by Wolfgang Senker and Matthias Gmeiner
submission deadline 20 Nov 2026 | Viewed by 193 | Submission Open
Keywords: neurosurgery; innovative neurosurgery; clinical translational neuroscience; precision surgery; advanced neuroimaging; minimally invasive neurosurgery; robotic and endoscopic techniques; artificial intelligence in neurosurgery; spine and craniovertebral surgery; functional and vascular neurosurgery; surgical innovation and outcomes
(This special issue belongs to the Section Clinical Neurology)
Challenges in Emergency Medicine
edited by and Gregor Prosen
submission deadline 20 Nov 2026 | Viewed by 189 | Submission Open
Keywords: in-hospital and prehospital care; care of the critically ill; resuscitation and post-resuscitation management; point-of-care ultrasound; emergency surgical and procedural interventions; digitalization and emerging technolo-gies; emergency medicine
(This special issue belongs to the Section Emergency Medicine)
Advancing Mechanical Ventilation in Critical Care: From Clinical Foundations to Personalized Strategies
edited by
submission deadline 20 Nov 2026 | Viewed by 188 | Submission Open
Keywords: mechanical ventilation; acute respiratory distress syndrome (ARDS); lung-protective ventilation; patient– ventilator interaction; personalized (precision) critical care
(This special issue belongs to the Section Intensive Care)
Clinical Diagnosis and Management of Neonatal Diseases—Second Edition
edited by and Ayala Gover
submission deadline 20 Nov 2026 | Viewed by 185 | Submission Open
Keywords: newborn; preterm; neonatal intensive care; low birth weight; point-of-care ultrasound; neonatal monitoring
(This special issue belongs to the Section Clinical Pediatrics)
Attention-Deficit/Hyperactivity Disorder, Psychiatric Comorbidity and Substance Use Disorders: Clinical Complexity Across the Lifespan
edited by Miriam Olivola and Paola Landi
submission deadline 20 Nov 2026 | Viewed by 183 | Submission Open
Keywords: ADHD; psychiatric comorbidity; substance use disorder; emotional dysregulation; impulsivity; dual diagnosis; adult ADHD; addiction vulnerability; neurodevelopmental disorders; transdiagnostic psychopathology
(This special issue belongs to the Section Mental Health)
Integrated Management of Cardiorenal Metabolic Syndrome: From Obesity to Chronic Kidney Disease submission deadline 20 Nov 2026 | Viewed by 182 | Submission Open
Keywords: cardiorenal metabolic syndrome; adipose tissue dysfunction; Insulin resistance; ectopic adiposity; cardiometabolic therapies
(This special issue belongs to the Section Endocrinology & Metabolism)
Hypertrophic Cardiomyopathy: From the Researcher Bench to the Clinical Patient Bedside
edited by , and Dejana R. Popović
submission deadline 20 Nov 2026 | Viewed by 175 | Submission Open
Keywords: hypertrophic cardiomyopathy; advanced imaging techniques; echocardiographic; cardiac magnetic resonance; biomarkers; surgical and interventional procedures
(This special issue belongs to the Section Cardiology)
Current Advances in Spinal Cord Stimulation Therapy
edited by Alessandro Dario
submission deadline 20 Nov 2026 | Viewed by 175 | Submission Open
Keywords: spinal cord stimulation; epidural stimulation; transcutaneous spinal cord stimulation; spasticity; neuropathic pain; Parkinson’ s disease; paraplegia; Persistent Spinal Pain Syndrome Type 1; Persistent Spinal Pain Syndrome Type 2; diabetic polyneuropathy; electrical waveforms
(This special issue belongs to the Section Clinical Neurology)
Recent Advances in Hip and Knee Arthroplasty: Clinical Trends
edited by
submission deadline 20 Nov 2026 | Viewed by 171 | Submission Open
Keywords: hip arthroplasty; knee arthroplasty; total joint replacement; osteoarthritis; surgical techniques; implant innovation; revision strategies; complication prevention; revision strategies
(This special issue belongs to the Section Orthopedics)
Cardiometabolic Health and Cardiovascular Outcomes: Pathophysiology to Implementation submission deadline 20 Nov 2026 | Viewed by 168 | Submission Open
Keywords: cardiometabolic disease; obesity; type 2 diabetes; cardiovascular risk; morbidity; mortality; prevention
(This special issue belongs to the Section Cardiovascular Medicine)
Colorectal Surgery: New Insights and Emerging Trends
edited by Marisa D. Santos, Nuno José Gomes Rama and Manuel Limbert
submission deadline 20 Nov 2026 | Viewed by 168 | Submission Open
Keywords: colorectal surgery; minimally invasive colorectal surgery; colorectal laparoscopic surgery; robotic-assisted colorectal surgery; precision colorectal surgery; enhanced recovery after surgery (ERAS); colorectal cancer; sphincter-preserving procedures; transanal surgery; pelvic floor surgery; personalized medicine; molecular profiling; biomarkers; artificial intelligence; image-guided surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Recent Advances in the Diagnosis and Treatment of Breast Cancer submission deadline 20 Nov 2026 | Viewed by 168 | Submission Open
Keywords: breast cancer screening; diagnosis; surgery; radiotherapy; targeted treatment; neoadjuvant; quality of life
(This special issue belongs to the Section Oncology)
Clinical Advances in Drug Safety and Polypharmacy submission deadline 20 Nov 2026 | Viewed by 160 | Submission Open
Keywords: polypharmacy; medication safety; adverse drug reactions; drug– drug interactions; pharmacovigilance; artificial intelligence in healthcare; precision medicine; deprescribing; pharmacoepidemiology
(This special issue belongs to the Section Pharmacology)
Robotic Surgery in Urology: Current Updates and Innovations
edited by Scott Leslie
submission deadline 20 Nov 2026 | Viewed by 159 | Submission Open
Keywords: robotics; oncology; prostatectomy; nephrectomy; bladder; transplant; minimally-invasive; nephroureterectomy; reconstructive; pyeloplasty; novel; laparoscopic
(This special issue belongs to the Section Nephrology & Urology)
Advanced Technologies in Thoracic Anesthesia
edited by and
submission deadline 20 Nov 2026 | Viewed by 155 | Submission Open
Keywords: thoracic anesthesia; thoracic analgesia; preoperative management; enhanced recovery after surgery; thoracic Block; video-assisted thoracic surgery; robotic-assisted thoracic surgery; post-thoracotomy syndrome; airway device
(This special issue belongs to the Section Anesthesiology)
Electroencephalography: Advances in Clinical Applications submission deadline 20 Nov 2026 | 1 articles | Viewed by 151 | Submission Open
Keywords: electroencephalography; clinical EEG; machine learning; deep learning; seizure detection; sleep EEG; brain– computer interface; neurodegenerative disease; consciousness assessment; automated diagnosis; multimodal neu-roimaging; human-AI benchmarking
(This special issue belongs to the Section Clinical Neurology)
Resuscitation and Shock: Evolving Concepts and Clinical Strategies in Acute Care
edited by , Barbara P. Fyntanidou and
submission deadline 20 Nov 2026 | Viewed by 148 | Submission Open
Keywords: resuscitation; shock; emergency medicine; critical care; hemodynamic monitoring; sepsis; trauma; vasopressors; fluid therapy; car-diopulmonary resuscitation (CPR); preclinical studies; cardiac arrest
(This special issue belongs to the Section Emergency Medicine)
Clinical Advances in Psychotic Disorders: Precision Diagnosis and Personalized Treatment
edited by
submission deadline 20 Nov 2026 | Viewed by 147 | Submission Open
Keywords: psychotic disorders; early detection; precision diagnosis; personalized interventions; functional recovery; personal recovery; cognitive remediation; psychosocial treatment; recovery-oriented care; individualized care plans; digital mental health; telepsychiatry; artificial intelligence; virtual reality; predictive modeling
(This special issue belongs to the Section Mental Health)
Challenges in the Diagnosis and Management of Chronic Respiratory Diseases submission deadline 20 Nov 2026 | Viewed by 145 | Submission Open
Keywords: chronic respiratory diseases; long-term respiratory care; comorbidities; COPD; asthma; interstitial lung disease; pulmonary rehabilitation
(This special issue belongs to the Section Respiratory Medicine)
Cardiomyopathy: Advances in Clinical Diagnosis and Treatment
edited by and Ali Amr
submission deadline 20 Nov 2026 | Viewed by 144 | Submission Open
Keywords: cardiomyopathy; precision medicine; heart failure; cardiac imaging; genetics; myocardial biopsy; arrhythmias; targeted therapy
(This special issue belongs to the Section Cardiology)
Echocardiography: Clinical Updates and Perspectives
edited by Isabella Leo and Giulia La Vecchia
submission deadline 20 Nov 2026 | Viewed by 143 | Submission Open
Keywords: echocardiography; cardiovascular imaging; three-dimensional echocardiography; speckle-tracking echocardiog-raphy; myocardial strain imaging; contrast echocardiography; transesophageal echocardiography; valvular heart disease; structural heart disease; artificial intelligence
(This special issue belongs to the Section Cardiovascular Medicine)
Application of Magnetic Resonance Imaging in Cardiovascular Disease
edited by Dhrubajyoti Bandyopadhyay, Aneesh S. Dhorepatil and
submission deadline 20 Nov 2026 | Viewed by 140 | Submission Open
Keywords: cardiac MRI; tricuspid regurgitation; parametric imaging; 4D flow; WIP; flow reserve; artificial intelligence
(This special issue belongs to the Section Cardiovascular Medicine)
New Challenges in Maternal–Fetal Medicine: 2nd Edition
edited by
submission deadline 20 Nov 2026 | Viewed by 139 | Submission Open
Keywords: thrombocytopenia in pregnancy; multiple pregnancies; placental abruption; DIC; sepsis; chorioamnionitis; cholestasis; postpartum hemorrhage; emergency cervical cerclage; problems in pregnancy and labor; pregnancy complications; spina bifida; fetal well-being evaluation
(This special issue belongs to the Section Obstetrics & Gynecology)
Hepato-Pancreato-Biliary (HPB) Surgery: Precision and Outcomes
edited by Florian W. R. Vondran, Felix Oldhafer and Celia Villodre
submission deadline 20 Nov 2026 | Viewed by 138 | Submission Open
Keywords: hepato-pancreato-biliary surgery; liver surgery; minimally invasive surgery; robotic surgery; multidisciplinary treatment
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Management Strategies for Traumatic Brain Injury in Neurocritical Care Unit
edited by Etrusca Brogi
submission deadline 20 Nov 2026 | Viewed by 135 | Submission Open
Keywords: traumatic brain injury; neurocritical care; intracranial pressure; cerebral perfusion; neuroprotection; TBI management; critical care strategies; outcome prediction; rehabilitation; monitoring
(This special issue belongs to the Section Clinical Neurology)
Clinical Insights into Hearing Disorders: Towards Precision Diagnosis to Improve Outcomes and Quality of Life
edited by
submission deadline 20 Nov 2026 | Viewed by 134 | Submission Open
Keywords: hearing loss; hearing disorders; hearing aids; cochlear implant; hearing outcomes; auditory rehabilitation; quality of life
(This special issue belongs to the Section Otolaryngology)
Hip Fracture and Surgery: Clinical Updates and Challenges: 2nd Edition
edited by
submission deadline 20 Nov 2026 | Viewed by 134 | Submission Open
Keywords: antiosteoporosis medication; fracture liaison service; osteosynthesis; total hip arthroplasty; hemiarthroplasty
(This special issue belongs to the Section Orthopedics)
Obesity and the Airway: Disease Mechanisms, Associated Conditions, and Management
edited by
submission deadline 20 Nov 2026 | Viewed by 134 | Submission Open
Keywords: obesity; airway; inflammation; rhinosinusitis; cerebrospinal fluid leak; asthma; chronic obstructive pulmonary disease; sleep; obstructive sleep apnea; intubation; laryngopharyngeal reflux; laryngotracheal stenosis
(This special issue belongs to the Section Respiratory Medicine)
Clinical Advancements in Radiology of Joint and Musculoskeletal Diseases
edited by
submission deadline 20 Nov 2026 | Viewed by 133 | Submission Open
Keywords: sports injuries; ligament injuries; ankle injury; prognostic imaging; individualized imaging; imaging algorithms; lower-extremity injury; clinical insights; knee injuries; groin and hip pain
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Advances in Adult Congenital Heart Disease: From Diagnosis to Long-Term Management
edited by Michael Huntgeburth
submission deadline 20 Nov 2026 | Viewed by 132 | Submission Open
Keywords: adult congenital heart disease; ACHD; long-term management; lifetime management; complications; arrhythmia; heart failure; endocarditis; pulmonary arterial hypertension; comorbidities; interventional treatment; surgical treatment; rehabilitation
(This special issue belongs to the Section Cardiology)
Innovations in Minimally Invasive and Personalized Urogynecology
edited by Günter Karl Noé and
submission deadline 20 Nov 2026 | Viewed by 130 | Submission Open
Keywords: urogynecology; pelvic floor disorders; minimally invasive reconstructive techniques; personalized and regenerative treatment strategies
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances and Challenges in the Diagnosis and Treatment of Epilepsy
edited by
submission deadline 20 Nov 2026 | Viewed by 129 | Submission Open
Keywords: epilepsy; diagnosis; treatment; epilepsy surgery; clinical management
(This special issue belongs to the Section Clinical Neurology)
New Technological Treatments and Methods in Neurorehabilitation
edited by
submission deadline 20 Nov 2026 | Viewed by 128 | Submission Open
Keywords: neurorehabilitation; robotics; virtual reality; exoskeleton; humankinesiology physiotherapy; stroke; parkinson's disease; gait; physical rehabilitation; rehabilitation interventions
(This special issue belongs to the Section Clinical Neurology)
Towards an Improved Understanding of Alzheimer's and Related Dementias: Interdisciplinary and Clinical Progress submission deadline 20 Nov 2026 | Viewed by 127 | Submission Open
Keywords: Alzheimer’ s disease; related dementias; neurodegeneration; biomarkers; neuroimaging; early diagnosis; cognitive decline; clinical management; therapeutic interventions; psychosocial care; risk factors; dementia prevention
(This special issue belongs to the Section Clinical Neurology)
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