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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Perspectives and Advances in Pharmacology in Pregnancy and Lactation

edited by Gregory W. Kirschen

submission deadline 31 Oct 2026 | Viewed by 108 | Submission Open

Keywords: pharmacokinetics; pharmacodynamics; pharmacovigilance; clinical trials; drug safety monitoring; breastfeeding; placental transfer; fetal development; neonatal outcomes

(This special issue belongs to the Section Obstetrics & Gynecology)

Pioneering the Future: AI and Innovation in Endometriosis, Adenomyosis and Adenomyoma Care

edited by

Camran R. Nezhat

, Alan DeCherney and Jeannette Lager

submission deadline 1 Nov 2026 | Viewed by 141 | Submission Open

Keywords: endometriosis; adenomyosis; adenomyoma; artificial intelligence in medicine; minimally invasive surgery; robotic surgery; surgical innovation; biomarkers and molecular diagnostics; fertility and reproductive outcomes; chronic pelvic pain

(This special issue belongs to the Section Obstetrics & Gynecology)

Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) and Concomitant Illnesses: Diagnostic and Therapeutic Implications

edited by Kamran Qureshi and Lewis Frey

submission deadline 5 Nov 2026 | 3 articles | Viewed by 3648 | Submission Open

Keywords: metabolic dysfunction-associated steatotic liver disease (MASLD); metabolic dysfunction-associated steatohepatitis (MASH); chronic liver diseases; metabolic syndrome; viral hepatitis; autoimmune liver diseases

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Insights into Pediatric Rheumatology

edited by

Roberta Naddei

and Maria Alessio

submission deadline 5 Nov 2026 | Viewed by 191 | Submission Open

Keywords: pediatric rheumatology; pediatric autoimmune diseases; juvenile idiopathic arthritis; macrophage activation syndrome; autoinflammatory syndromes; juvenile dermatomyositis; childhood-onset systemic lupus erythematosus; juvenile systemic and localized sclerosis; pediatric vasculitides

(This special issue belongs to the Section Clinical Pediatrics)

COVID-19 and Endocrine Complications

edited by

Kamyar Asadipooya

submission deadline 10 Nov 2026 | 4 articles | Viewed by 5244 | Submission Open

Keywords: adrenal; ACE2; diabetes; gonads; pituitary; SARS-CoV-2; thyroid

(This special issue belongs to the Section Endocrinology & Metabolism)

New Clinical Advances in Depressive Disorders and Treatment-Resistant Depression

edited by Giacomo d'Andrea and

Miriam Olivola

submission deadline 10 Nov 2026 | 2 articles | Viewed by 2771 | Submission Open

Keywords: treatment-resistant depression; MDD; ketamine; esketamine; rTMS; psylocibin; bipolar depression; clinical pheno-typing; precision psychiatry; biomarkers

(This special issue belongs to the Section Mental Health)

Precision and Innovation in Spine Surgery: Advanced Techniques for Spinal Disorders

edited by

Jung Woo Hur

submission deadline 10 Nov 2026 | 3 articles | Viewed by 921 | Submission Open

Keywords: minimally invasive spine surgery; endoscopic spine surgery; motion preservation; disc arthroplasty; anterior lumbar interbody fusion; robotic spine surgery; spinal navigation; spinal deformity correction; degenerative disc disease; enhanced recovery after spine surgery; artificial intelligence in spine surgery; dynamic stabilization

(This special issue belongs to the Section Orthopedics)

Revolutionizing Arrhythmia Therapy: Novel Approaches in Pacing and Defibrillation

edited by

Amato Santoro

and

Alberto Palazzuoli

submission deadline 10 Nov 2026 | 1 articles | Viewed by 806 | Submission Open

Keywords: cardiac resynchronization therapy; conduction system pacing; left bundle branch area pacing; S-ICD; EV-ICD

(This special issue belongs to the Section Cardiology)

Latest Updates on Liver Surgery, Liver Regeneration, and Liver Transplantation

edited by Ivan Romic and Goran Pavlek

submission deadline 10 Nov 2026 | 1 articles | Viewed by 585 | Submission Open

Keywords: liver surgery; transplant; regeneration; oncology; liver regeneration

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Musculoskeletal Disorders and Functional Rehabilitation: Innovations, Challenges and Future Directions

edited by

Mohammad Al-Amri

and

Tomasz Cudejko

submission deadline 10 Nov 2026 | Viewed by 180 | Submission Open

Keywords: musculoskeletal disorders; functional rehabilitation; biomechanics; artificial intelligence; wearable sensors; digital biomarkers; personalised rehabilitation; digital health; mobility outcome; gait

(This special issue belongs to the Section Orthopedics)

Innovative Therapies for Neurological Disorders

edited by Natalia Szejko

submission deadline 10 Nov 2026 | Viewed by 168 | Submission Open

Keywords: neurological disorders; innovative therapies; neuromodulation; digital therapeutics; precision medicine; neuroreha-bilitation; movement disorders; neurodegenerative diseases; functional neurological disorders; translational neuro-science

(This special issue belongs to the Section Clinical Neurology)

Innovations in Knee Arthroplasty: Implants, Alignment, and Technology

edited by

Vicente J. León-Muñoz

and

Joaquín Moya-Angeler

submission deadline 10 Nov 2026 | Viewed by 150 | Submission Open

Keywords: knee arthroplasty; implant design; implant materials; alignment strategies; robotics in arthroplasty; soft tissue balancing; computer-assisted surgery; tribology; patient-reported outcomes; revision knee arthroplasty; survivorship and registry data

(This special issue belongs to the Section Orthopedics)

Decoding Male Reproductive Health: Clinical and Laboratory Perspectives

edited by

Rocío Núñez-Calonge

and Ana Segura

submission deadline 10 Nov 2026 | Viewed by 130 | Submission Open

Keywords: male reproductive health; male infertility; andrology; laboratory diagnosis; semen analysis

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Targeted Therapy for Amyotrophic Lateral Sclerosis

edited by Annemarie Hübers

submission deadline 10 Nov 2026 | Viewed by 128 | Submission Open

Keywords: amyotrophic lateral sclerosis; targeted therapy; motor neuron disease; neurodegeneration; disease-modifying therapy

(This special issue belongs to the Section Clinical Neurology)

Advances and Emerging Trends in Maternal–Fetal Medicine: From Diagnostics to Fetal Therapy

edited by Isabella Fabietti

submission deadline 10 Nov 2026 | Viewed by 116 | Submission Open

Keywords: maternal– fetal medicine; high-risk pregnancy; prenatal diagnosis; fetal therapy and surgery; fetal growth restriction; placental disorders; preterm birth; biomarkers; genomics; precision medicine; artificial intelligence in obstetrics

(This special issue belongs to the Section Obstetrics & Gynecology)

Perioperative and Glycemic Control in General Surgery

edited by

Baudolino Mussa

submission deadline 10 Nov 2026 | Viewed by 96 | Submission Open

Keywords: perioperative glycemic control; hypoglycemia prevention; continuous glucose monitoring; ERAS; GLP-1 receptor agonists; SGLT-2 inhibitors; surgical stress response; insulin therapy; patient quality of life; metabolic surgery

(This special issue belongs to the Section General Surgery)

Clinical Advancements and Breakthroughs in Heart Failure and Transplant Cardiology

edited by David Snipelisky

submission deadline 10 Nov 2026 | Viewed by 61 | Submission Open

Keywords: heart failure; cardiac transplantation; mechanical circulatory support; advanced heart failure; left ventricular assist devices; cardiomyopathies

(This special issue belongs to the Section Cardiology)

Occupational Health: Current Status and Future Challenges

edited by

Guillermo Moreno Muñoz

Manuel Romero Saldaña

and

Alfonso Meneses Monroy

submission deadline 12 Nov 2026 | 1 articles | Viewed by 496 | Submission Open

Keywords: occupational health; future challenges; work-related diseases; workplace prevention; psychosocial risks; workers’ well-being; occupational safety; digitalization at work

(This special issue belongs to the Section Epidemiology & Public Health)

Advances in Clinical Management of Breast Surgery and Reconstruction

edited by Siba Haykal and Stav Brown

submission deadline 13 Nov 2026 | Viewed by 93 | Submission Open

Keywords: breast reconstructive surgery; breast reconstruction; microsurgery; plastic and reconstructive surgery; breast cancer; surgical oncology; mastectomy; axillary lymph node dissection; lymphedema; cancer-related lymphedema

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Cardiac Amyloidosis and Heart Failure: Clinical Pathophysiology, Diagnosis, and Therapeutic Strategies

edited by Ilaria Dentamaro and

Laura Fusini

submission deadline 15 Nov 2026 | 4 articles | Viewed by 3376 | Submission Open

Keywords: cardiology; cardiac heart failure; cardiac amyloidosis; cardiac imaging; cardiomyopathy

(This special issue belongs to the Section Cardiology)

Pediatric Pulmonology: Recent Developments and Emerging Trends—Second Edition

edited by Athina L. Papadopoulou

submission deadline 15 Nov 2026 | Viewed by 186 | Submission Open

Keywords: definition of breath sounds; lung– gut axis pathophysiology; disease endotypes and phenotypes; asthma management in children; bronchiolitis spectrum; pediatric bronchopulmonary dysplasia; pulmonary function testing in pediatric patients; pediatric sleep-disordered breathing; neonatal respiratory distress syndrome; childhood interstitial lung diseases; pulmonary hypertension in children; biomarkers in pediatric lung diseases; allergy and the lungs; diagnostic and therapeutic challenges in bronchoscopy; gene therapy in cystic fibrosis

(This special issue belongs to the Section Clinical Pediatrics)

Endometrial Disorders and Pregnant Outcome: Clinical Insights and Perspectives

edited by Raffaella Di Girolamo

submission deadline 15 Nov 2026 | Viewed by 150 | Submission Open

Keywords: endometrial microbiome; fertility preservation; pregnancy outcome; reproductive medicine; ART

(This special issue belongs to the Section Obstetrics & Gynecology)

Emergency Ultrasound: Rapid Diagnosis and Clinical Applications

edited by

Dorota Sobczyk

submission deadline 15 Nov 2026 | Viewed by 140 | Submission Open

Keywords: emergency ultrasound; point-of-care ultrasound (POCUS); rapid diagnostic; acute care; bedside imaging

(This special issue belongs to the Section Emergency Medicine)

Clinical Progress in Cardiovascular Surgery

edited by Georgios P. Georghiou

submission deadline 15 Nov 2026 | Viewed by 138 | Submission Open

Keywords: cardiovascular surgery; CABG; valvular surgery; aortic surgery; postoperative atrial fibrillation; cardio-oncology; minimally invasive cardiac surgery; mechanical circulatory support; outcomes research; ESC-aligned cardiovascular care

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Interventions for Cognitive Impairment and Neurological Disorders

edited by

Agustín Aibar Almazán

submission deadline 15 Nov 2026 | Viewed by 106 | Submission Open

Keywords: exercise; mental disorders; mental health; physical function; depression; anxiety; cognitive function; lifespan; physical activity

(This special issue belongs to the Section Mental Health)

Cognitive and Emotional Health in Older Adults: Recent Clinical Advances

edited by Milan Chang

submission deadline 15 Nov 2026 | Viewed by 100 | Submission Open

Keywords: activities of daily living (ADL); sarcopenia; mobility; physical activity; fall prevention; fear of falling (FOF); depres-sive symptoms; cognitive reserve; self-efficacy; life satisfaction

(This special issue belongs to the Section Geriatric Medicine)

Non-Operating Room Anesthesia

edited by Basavana Goudra

submission deadline 15 Nov 2026 | Viewed by 81 | Submission Open

Keywords: anesthesia; oxygenation; sedative agents; ventilation; airway management; hemodynamic monitoring

(This special issue belongs to the Section Anesthesiology)

Clinical Advances in Pain Management: 2nd Edition

edited by Jamal Hasoon and Omar Viswanath

submission deadline 16 Nov 2026 | Viewed by 149 | Submission Open

Keywords: postoperative pain; acute pain; chronic pain; nociceptive; analgesia; analgesics; interventional pain procedures

(This special issue belongs to the Section Anesthesiology)

Fibromyalgia: Diagnostic Progress and Therapeutic Advances

edited by

Casandra Isabel Montoro Aguilar

submission deadline 17 Nov 2026 | 1 articles | Viewed by 1660 | Submission Open

Keywords: fibromyalgia; chronic pain; central sensitization; diagnostic biomarkers; advanced imaging; molecular markers; autonomic nervous system; cardiovascular regulation; emotional processing; cognitive dysfunction; fatigue; pain modulation; neuromodulation; tDCS

(This special issue belongs to the Section Clinical Neurology)

Advancing the Clinical Management of Myeloproliferative Neoplasms (MPNs)

edited by

Priya Sriskandarajah

and

Natalia Curto-Garcia

submission deadline 18 Nov 2026 | 1 articles | Viewed by 379 | Submission Open

Keywords: myeloproliferative neoplasms; targeted therapies; emerging therapies; outcomes; thrombosis; thrombosis prevention

(This special issue belongs to the Section Hematology)

Perioperative Care and Anaesthesia: Clinical Challenges and Future Perspectives

edited by

Mihai Stefan

submission deadline 18 Nov 2026 | Viewed by 97 | Submission Open

Keywords: perioperative hemodynamic monitoring; patient blood management; perioperative bleeding and coagulopathy; cardiac anesthesia and critical care; mechanical circulatory support; goal-directed therapy; viscoelastic testing; perioperative anemia; transfusion; iron deficiency; perioperative shock

(This special issue belongs to the Section Anesthesiology)

Pediatric Dentistry: Recent Advances, Current Issues and Future Challenges

edited by

Liliana Szyszka-Sommerfeld

and

Krzysztof Woźniak

submission deadline 20 Nov 2026 | 7 articles | Viewed by 22705 | Submission Open

Keywords: pediatric dentistry; recent advances; current issues; future challenges; orthodontic issues; preventive strategies; access to care disparities; behavioral management; multidisciplinary collaboration; oral health

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Chronic Kidney Disease: Clinical Updates and Perspectives, Opportunities and Challenges, 2nd Edition

edited by Botond Csiky

submission deadline 20 Nov 2026 | 3 articles | Viewed by 10080 | Submission Open

Keywords: chronic kidney disease progression; cardiovascular risk factors; diabetes mellitus; obesity; kidney transplantation; survival; pathophysiology of CKD; hemodialysis; peritoneal dialysis; metabolic and mineral bone disease

(This special issue belongs to the Section Nephrology & Urology)

Assisted Reproductive Technology and Infertility Treatment: Current Updates and Perspectives—2nd Edition

edited by Nikos Nikolettos and

Angeliki Tiptiri-Kourpeti

submission deadline 20 Nov 2026 | 4 articles | Viewed by 9941 | Submission Open

Keywords: assisted reproduction technology (ART); infertility; treatment; reproduction; IVF

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Integrated Clinical Approaches to Managing Multimorbidity and Multiple Disabilities: Advances in Rehabilitation and Therapeutic Strategies

edited by

Masahiro Kohzuki

submission deadline 20 Nov 2026 | 4 articles | Viewed by 9350 | Submission Open

Keywords: heart; lung; kidney; liver; bone; brain

(This special issue belongs to the Section Clinical Rehabilitation)

Advances in Ablation Therapy for Atrial Fibrillation: Innovations and Clinical Applications

edited by Ioanna Koniari

submission deadline 20 Nov 2026 | 4 articles | Viewed by 4959 | Submission Open

Keywords: atrial fibrillation; ablation; PFA; PVI; non-thermal energy; mapping system

(This special issue belongs to the Section Cardiology)

Research Progress in Pediatric Endocrinology

edited by

Federico Baronio

submission deadline 20 Nov 2026 | 2 articles | Viewed by 4801 | Submission Open

Keywords: pediatric endocrinology; rare endocrine disorders; precision medicine; congenital adrenal hyperplasia (CAH); short stature genetics; severe childhood obesity; glp-1 receptor agonists; endocrine disruptors; artificial intelligence (AI) in endocrinology; newborn screening

(This special issue belongs to the Section Clinical Pediatrics)

Total Joint Arthroplasty: Clinical Advances and Innovations in Surgical Techniques and Rehabilitation

edited by

Mattia Loppini

, Marco Minelli and Federico Della Rocca

submission deadline 20 Nov 2026 | 5 articles | Viewed by 4744 | Submission Open

Keywords: total joint arthroplasty; hip replacement; knee arthroplasty; robotic-assisted surgery; minimally invasive techniques; implant design; postoperative rehabilitation; periprosthetic joint infection; surgical innovation

(This special issue belongs to the Section Orthopedics)

Innovations in Thoracic Surgery and Disease Management: Integrating Genomics, Technology, and Multidisciplinary Care

edited by

Marco Scarci

and

Savvas Lampridis

submission deadline 20 Nov 2026 | 6 articles | Viewed by 4662 | Submission Open

Keywords: thoracic surgery; thoracic disease; genomic medicine; artificial intelligence; advanced imaging; multidisciplinary care; minimally invasive surgery; robotic surgery; precision medicine

(This special issue belongs to the Section Respiratory Medicine)

Current Trends in Urogynecology: 3rd Edition

edited by

Tomasz Rechberger

submission deadline 20 Nov 2026 | 3 articles | Viewed by 3490 | Submission Open

Keywords: urogynecological surgery (uterovaginal prolapse; urinary incontinence; fistulas); OAB; pharmacology; physiotherapy; LUTS

(This special issue belongs to the Section Obstetrics & Gynecology)

New Insights in Paediatric Endocrinology

edited by

Marco Fiore

submission deadline 20 Nov 2026 | 5 articles | Viewed by 3350 | Submission Open

Keywords: endocrinology; pediatrics; hormones; therapy and treatment; adolescents; newborns

(This special issue belongs to the Section Clinical Pediatrics)

Clinical Insights in Maternal–Fetal Medicine

edited by Moti Gulersen

submission deadline 20 Nov 2026 | 2 articles | Viewed by 2433 | Submission Open

Keywords: preterm birth; antenatal corticosteroids; preeclampsia; ultrasound; fetal growth; congenital anomalies; infection; maternal morbidity; diabetes; multiple gestation

(This special issue belongs to the Section Obstetrics & Gynecology)

Acute Coronary Syndromes | Circulation Research

edited by

Leslie Marisol Lugo Gavidia

and

Roberto Pedrinelli

submission deadline 20 Nov 2026 | 3 articles | Viewed by 2387 | Submission Open

Keywords: acute coronary syndromes; cardiovascular risk; individualized therapy; STEMI; risk factors

(This special issue belongs to the Section Cardiology)

Clinical Aspects of Return to Sport After Injuries: 2nd Edition

edited by

Anna Mika

and

Łukasz Oleksy

submission deadline 20 Nov 2026 | 2 articles | Viewed by 1955 | Submission Open

Keywords: musculoskeletal system; tissue overload; diagnostic methods; rehabilitation; treatment; injury prevention; return to sport; rehabilitation medicine; sports medicine

(This special issue belongs to the Section Sports Medicine)

Foot and Ankle Surgery: Clinical Challenges and New Insights: 2nd Edition

edited by

Byung-Ki Cho

submission deadline 20 Nov 2026 | 3 articles | Viewed by 1730 | Submission Open

Keywords: hallux valgus; minimal invasive correction; chronic ankle instability; arthroscopic Brostrom procedure; suture-tape augmentation; ankle arthritis; total ankle arthroplasty; ankle arthrodesis

(This special issue belongs to the Section Orthopedics)

Cardiac MRI: Current Techniques and Future Directions

edited by

Édouard Gerbaud

submission deadline 20 Nov 2026 | 1 articles | Viewed by 1439 | Submission Open

Keywords: cardiac magnetic resonance imaging; technology; sequences; applications; acute coronary syndrome; intravascular imaging; CT-scanner

(This special issue belongs to the Section Cardiology)

Advances and Clinical Comparisons in Analgesia: Pharmacological, Non-Pharmacological, and Device-Based Approaches

edited by

Sang Hun Kim

and

Yoon Ji Choi

submission deadline 20 Nov 2026 | 1 articles | Viewed by 1391 | Submission Open

Keywords: acute pain; chronic pain; postoperative pain; non-pharmaceutical; pharmaceutical; analgesia; clinical

(This special issue belongs to the Section Anesthesiology)

Integrated Management of Long COVID: Fatigue, Emerging Evidence, and Therapeutic Innovations

edited by

Yuki Otsuka

submission deadline 20 Nov 2026 | 3 articles | Viewed by 1009 | Submission Open

Keywords: long COVID; post-COVID condition; fatigue; clinical management; rehabilitation; therapeutic innovation; integrative medicine; biomarkers

(This special issue belongs to the Section Infectious Diseases)

Patient Blood Management Throughout the Hospital Pathway: Admission, Surgery, ICU, and Beyond

edited by

Piotr F. Czempik

and Kai Zacharowski

submission deadline 20 Nov 2026 | 1 articles | Viewed by 968 | Submission Open

Keywords: anemia; blood health; blood loss; blood transfusion; coagulopathy; critical care; hemostasis; laboratory diagnostics; patient blood management; perioperative care; point-of-care testing; transfusion medicine; thrombosis; trauma; viscoelastic testing

(This special issue belongs to the Section Intensive Care)

Thromboembolic Disease and Antithrombotic Therapy: 2nd Edition

edited by Prahlad Ho

submission deadline 20 Nov 2026 | 1 articles | Viewed by 915 | Submission Open

Keywords: thrombosis; pulmonary embolism; manticoagulation; DOAC (direct oral anticoagulants); DVT (deep vein throm-bosis); novel anticoagulants (factor XIa inhibitors); thrombin; fibrin generation; risk stratification; biomarkers; Vir-chow’ s triad; post thrombotic syndrome

(This special issue belongs to the Section Hematology)

Displaying special issue 1151-1200 on page 24 of 31.

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