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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Pediatric Surgery—Current Hurdles and Future Perspectives—2nd Edition

edited by

Osnat Zmora

submission deadline 20 Jul 2026 | Viewed by 38 | Submission Open

Keywords: congenital anomalies; esophageal atresia; anorectal malformations; pediatric trauma; necrotizing enterocolitis; pediatric oncology; biliary atresia

(This special issue belongs to the Section Clinical Pediatrics)

Gynecologic Cancers: Current Clinical Management and Multidisciplinary Treatment Strategies

edited by

Iason Psilopatis

and

Christos Damaskos

submission deadline 20 Jul 2026 | Viewed by 37 | Submission Open

Keywords: gynecologic; cancer; uterus; ovarian; endometrial; cervical

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Challenges in Heart Failure Management: 2nd Edition

edited by Paolo Severino, Gaetano M. Ruocco and

Andrea D'Amato

submission deadline 20 Jul 2026 | Viewed by 37 | Submission Open

Keywords: acute heart failure; chronic heart failure; inotropic support; left ventricular assist device; cardiac contractility modulation; guanylate cyclase stimulators; quality of life; telemedicine; palliative care

(This special issue belongs to the Section Cardiology)

Clinical Advances in Pediatric Hepatobiliary Surgery

edited by Ioannis A. Ziogas

submission deadline 20 Jul 2026 | Viewed by 36 | Submission Open

Keywords: pediatric hepatobiliary surgery; pediatric transplantation; pediatric surgery; liver transplantation; biliary atresia; choledochal cyst; liver cancer

(This special issue belongs to the Section Clinical Pediatrics)

Current Therapeutic Approaches to Addictive Disorders

edited by Linda Haddad

submission deadline 20 Jul 2026 | Viewed by 36 | Submission Open

Keywords: addiction treatment; dependence; withdrawal management; relapse prevention; recovery; rehabilitation and support

(This special issue belongs to the Section Mental Health)

Hypertrophic Cardiomyopathy: New Insights into Complications and Treatment

edited by Ilaria Dentamaro and Ciro Santoro

submission deadline 20 Jul 2026 | Viewed by 35 | Submission Open

Keywords: hypertrophic cardiomyopathy; complications; risk stratification; multimodality imaging; myosin inhibitors; precision medicine

(This special issue belongs to the Section Cardiology)

Acute Coronary Syndrome(ACS): From Emergency Intervention to Long-Term Prevention

edited by Marco Ciardetti and Alessio Mattesini

submission deadline 20 Jul 2026 | Viewed by 34 | Submission Open

Keywords: acute coronary syndrome; primary percutaneous coronary intervention; antithrombotic therapy; secondary prevention; risk stratification

(This special issue belongs to the Section Cardiology)

Misconceptions and Myths in Dermatology: From Clinic to Clarity

edited by Simon M. Mueller and Oliver Brandt

submission deadline 20 Jul 2026 | Viewed by 33 | Submission Open

Keywords: misconceptions; misunderstanding; myths; errors; mistakes; skin; dermatology

(This special issue belongs to the Section Dermatology)

Clinical Advances in Application of Echocardiography

edited by

Ramdas G. Pai

submission deadline 20 Jul 2026 | Viewed by 32 | Submission Open

Keywords: echocardiography; Doppler; transesophageal echocardiography; stain imaging; valvular hemodynamics; non valvular hemodynamics; interventional echocardiography; 3-dimensional echocardiography; tissue Doppler imaging

(This special issue belongs to the Section Cardiology)

The Wide World of Antinuclear Antibodies (ANA)-Associated Disorders: Patterns, Clinical Phenotypes, Comorbidities, and Impact

edited by

Daniela Opris-Belinski

submission deadline 20 Jul 2026 | Viewed by 32 | Submission Open

Keywords: antinuclear antibodies (ANA); ANA-associated disorders; clinical phenotypes; ANA patterns; lupus; Sjö gren’ s disease; systemic sclerosis; idiopathic inflammatory myopathies; comorbidities; connective tissue diseases; overlap syndromes; undifferentiated connective tissue disease; risk stratification; patient-centered management

(This special issue belongs to the Section Immunology & Rheumatology)

Reducing Modifiable Risk Factors to Prevent and Control Non-Communicable Diseases: 2nd Edition

edited by

Daniele Piovani

and

Gisella Figlioli

submission deadline 20 Jul 2026 | Viewed by 32 | Submission Open

Keywords: non-communicable disease; chronic disease; cardiovascular disease; cancer; chronic respiratory disease; diabetes; mental health; tobacco use; physical inactivity; unhealthy diet; alcohol use; disease prevention

(This special issue belongs to the Section Epidemiology & Public Health)

Gastroparesis: Emerging Insights and Endoscopic Therapeutic Strategies

edited by Sabrina Testoni

submission deadline 20 Jul 2026 | Viewed by 31 | Submission Open

Keywords: gastroparesis; gastric dismotility; gastric emptying; gastric per-oral miotomy; pyloromyotomy; gastric electric stim-ulation; botulinum toxin

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Updates on Reconstructive Urology

edited by

Fabio Campodonico

submission deadline 20 Jul 2026 | Viewed by 30 | Submission Open

Keywords: reconstructive urology; urethral stenosis; urethroplasty; urethral diverticulum; ureteral stenosis; male incontinence; urinary diversion; hypospadias; microsurgery; experimental microsurgery; bladder diverticulum; neobladder

(This special issue belongs to the Section Nephrology & Urology)

Novel Perspectives in Transcatheter Aortic Valve Implantation

edited by Nay Min Htun

submission deadline 20 Jul 2026 | Viewed by 30 | Submission Open

Keywords: TAVI; life-time management; TAVI-in-TAVI; bicuspid valve; pure aortic regurgitation; small annuli

(This special issue belongs to the Section Cardiology)

Current Advances in Non-Trauma Emergency Critical and Resuscitation Medicine

edited by

Sebastian Bergrath

submission deadline 20 Jul 2026 | Viewed by 30 | Submission Open

Keywords: resuscitation; non-trauma critically ill; emergency department; resuscitation room management; neuro-critical emergency care; emergency department critical care

(This special issue belongs to the Section Emergency Medicine)

Therapeutic Advances in Hematological Malignancies: New Breakthroughs and Future Directions

edited by Seema Naik

submission deadline 20 Jul 2026 | Viewed by 29 | Submission Open

Keywords: leukemia; lymphoma; myeloma; cell therapy; targeted therapy

(This special issue belongs to the Section Hematology)

Optimizing Radiotherapy in Clinical Practice: Innovation and Outcomes

edited by

Sarah Han-Oh

, Senthamizhchelvan Srinivasan and Joseph Moore

submission deadline 20 Jul 2026 | Viewed by 26 | Submission Open

Keywords: AI-assisted automated contouring and planning; AI-assisted quality assurance; AI-assisted safety and quality improvement; radiotherapy automation; radiomics; radiotherapy error detection; personalized radiopharmaceutical therapy; theranostics; online adaptive radiotherapy; real-time treatment adaptation; image-guided radiotherapy (IGRT); AI-assisted online adaptation; personalized radiotherapy; cone-beam CT adaptation

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Current Measures for Diagnosis, Monitoring, and Outcome Assessment in Orthopedics, Traumatology, and Hand Surgery, 2nd Edition

edited by

Paweł Reichert

and

Piotr Morasiewicz

submission deadline 20 Jul 2026 | Viewed by 25 | Submission Open

Keywords: clinical evaluation; hand surgery; orthopaedics; performance-based measures; physical examination; reliability; traumatology

(This special issue belongs to the Section Orthopedics)

Clinical Research on Robot-Assisted Thoracic Surgery and Lung Surgery

edited by Marco Scarci

submission deadline 20 Jul 2026 | Viewed by 24 | Submission Open

Keywords: robot-assisted thoracic surgery; robotic lung surgery; minimally invasive surgery; lobectomy; segmentectomy; thoracic oncology; surgical outcomes; learning curve; clinical research; robotic technology

(This special issue belongs to the Section General Surgery)

What We See Through Cardiac Imaging: Second Edition

edited by

Valeria Pergola

and

Francesca Mantovani

submission deadline 20 Jul 2026 | Viewed by 20 | Submission Open

Keywords: cardiomyopathies; multimodality imaging; echocardiography; cardiac-computed tomography; cardiac magnetic resonance; prognosis; arrhythmias; heart failure

(This special issue belongs to the Section Cardiology)

Challenges and Solutions in Geriatric Fracture

edited by Detlef Van der Velde and

Henk Jan Schuijt

submission deadline 20 Jul 2026 | Viewed by 20 | Submission Open

Keywords: geriatric; fracture; frailty; hip fracture; comorbidity; perioperative optimization; orthogeriatrics; rehabilitation; shared decision-making; postoperative outcomes; mortality and morbidity; functional recovery; multidisciplinary care; quality of life; recovery; mobility; palliative care

(This special issue belongs to the Section Geriatric Medicine)

Head and Neck Surgery: Immunotherapy’s Role in Shaping Treatment Paradigms

edited by

Mark S. Swanson

submission deadline 20 Jul 2026 | Viewed by 17 | Submission Open

Keywords: head and neck surgery; otorhinolaryngology; ENT; transoral surgery; laryngeal surgery; laryngeal carcinoma; sinonasal surgery; oral cancer; oropharyngeal cancer; laryngectomy; immunotherapy; head and neck cancer; cutaneous cancer

(This special issue belongs to the Section Otolaryngology)

Corneal Diseases: Clinical Perspectives from Diagnosis to Treatment

edited by Davide Romano

submission deadline 20 Jul 2026 | Viewed by 11 | Submission Open

Keywords: cornea; keratoplasty; keratitis; keratoconus; clinical perspectives

(This special issue belongs to the Section Ophthalmology)

Advances in Clinical Practice and Personalized Approaches in Cardiovascular Disease—2nd Edition

edited by Joseph B. Selvanayagam and

Sivabaskari Pasupathy

submission deadline 20 Jul 2026 | Viewed by 9 | Submission Open

Keywords: personalized medicine; cardiovascular innovations; cardiac imaging; risk assessment; multimodal imaging; therapeutic strategies; data-driven decision making; clinical outcomes; translational research

(This special issue belongs to the Section Cardiovascular Medicine)

Psychological Affliction in Pregnancy, Delivery and Postpartum Period: A Multidisciplinary Approach

edited by

Beata Pięta

and

Edyta Barnas̈

submission deadline 24 Jul 2026 | Viewed by 119 | Submission Open

Keywords: maternal mental health; pregnancy; postpartum depression; perinatal anxiety; midwifery; multidisciplinary care

(This special issue belongs to the Section Mental Health)

Clinical Strategies for Preventing Healthcare-Associated Infections

edited by

Monica Marilena Țânțu

Rogozea Liliana Marcela

and

Corneliu Ovidiu Vrancianu

submission deadline 24 Jul 2026 | Viewed by 73 | Submission Open

Keywords: healthcare-associated infections; multidrug resistance; prevention; screening scales; polymicrobial infections; oppor-tunistic infections; sepsis

(This special issue belongs to the Section Infectious Diseases)

Recent Clinical Advances in Pelvic Organ Prolapse

edited by José Antonio García-Mejido and José Antonio Sainz-Bueno

submission deadline 24 Jul 2026 | Viewed by 54 | Submission Open

Keywords: pelvic organ prolapse; pelvic floor dysfunction; urogynecology; pelvic reconstructive surgery; pathophysiology of POP; surgical techniques; conservative management; patient-reported outcomes; biomaterials in pelvic surgery; levator ani muscle

(This special issue belongs to the Section Obstetrics & Gynecology)

Rewriting Metastatic Colorectal Cancer Management: Innovative Frontiers in Clinical Diagnosis and Personalized Oncology

edited by

Maria Maddalena Laterza

submission deadline 24 Jul 2026 | Viewed by 42 | Submission Open

Keywords: molecular profiling; liquid biopsy; targeted therapy; immunotherapy; biomarkers treatment; sequencing; tumor heterogeneity; personalized medicine

(This special issue belongs to the Section Oncology)

Clinical Advances in Spinal Neurosurgery

edited by Jang-Won Yoon

submission deadline 25 Jul 2026 | 2 articles | Viewed by 2358 | Submission Open

Keywords: minimally invasive spine surgery; lateral lumbar interbody fusion; endoscopic spine surgery; patient-reported out-comes; functional assessment; perioperative care; surgical decision-making

(This special issue belongs to the Section Clinical Neurology)

Clinical Updates on Transcatheter Structural Heart Disease Interventions

edited by Nazan Puluca and Hendrik Ruge

submission deadline 25 Jul 2026 | Viewed by 61 | Submission Open

Keywords: interventional valve therapy; TAVR; TEER; TMVR; mitral valve; tricuspid valve; coronary access

(This special issue belongs to the Section Cardiology)

High-Risk Pregnancy Management: From Prenatal Care to Postpartum Outcomes

edited by

Angela Vinturache

submission deadline 25 Jul 2026 | Viewed by 60 | Submission Open

Keywords: high-risk pregnancy; prenatal care; postpartum outcomes; postpartum mental health; birth trauma; AI in obstetrics; medico-legal liability; equity & culturally safe care; indigenous and rural/remote care; EMR-enabled decision support; quality trend monitoring; maternal morbidity and mortality; perinatal morbidity; standardized care bundles & pathways

(This special issue belongs to the Section Obstetrics & Gynecology)

Recent Advance in Bariatric Surgery

edited by

Lidia Castagneto Gissey

submission deadline 25 Jul 2026 | Viewed by 50 | Submission Open

Keywords: bariatric surgery; metabolic surgery; minimally invasive surgery; robotic surgery; endoscopic bariatric procedures; obesity management; type 2 diabetes remission; perioperative care; long-term outcomes; enhanced recovery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Sleep Disorders: Current Research and Future Directions—Second Edition

edited by Martina Vendrame

submission deadline 25 Jul 2026 | Viewed by 49 | Submission Open

Keywords: obstructive sleep apnea; parasomnia; idiopathic hypersomnia; periodic limb movement disorder; periodic limb move-ment of sleep

(This special issue belongs to the Section Clinical Neurology)

Diagnosis and Treatment of Pleura and Lung: Clinical Advances in Intensive Care

edited by Alen Protić and

Vlatka Sotosek

submission deadline 25 Jul 2026 | Viewed by 40 | Submission Open

Keywords: thoracic drainage; lung recruitment; lung ultrasound; pleural effusion; pneumothrax; B-line; lung atelectasis

(This special issue belongs to the Section Intensive Care)

Hearing Loss Management in Children: Guidelines and Interventions

edited by Lone Percy-Smith

submission deadline 25 Jul 2026 | Viewed by 39 | Submission Open

Keywords: early intervention for populations with HL; emerging new generations of persons with HL; quality assurance of interventions for populations with HL; self-assessments of quality of life

(This special issue belongs to the Section Clinical Pediatrics)

Complications Related to Coronary Artery Disease and Secondary Prevention Strategies

edited by Nazanin Rajai

submission deadline 25 Jul 2026 | Viewed by 39 | Submission Open

Keywords: coronary artery disease; complications; secondary prevention; myocardial infarction; cardiovascular risk; heart failure; arrhythmias; imaging; biomarkers; cardiovascular pharmacotherapy

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Application of Endoscopic Submucosal Dissection in Malignant Gastrointestinal Tumors and Precursors—2nd Edition

edited by

Rainer Schöfl

and

Reinhold Függer

submission deadline 25 Jul 2026 | Viewed by 37 | Submission Open

Keywords: endoscopy; endoscopic submucosal dissection; endoscopic surgery; laparoscopic surgery; minimally invasive surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current Advances and Future Perspectives in Cardiac Arrest and Cardiogenic Shock

edited by Giulia Maj

submission deadline 25 Jul 2026 | Viewed by 36 | Submission Open

Keywords: cardiogenic shock; left ventricular unloading; biomarkers; recovery; cardiac arrest

(This special issue belongs to the Section Emergency Medicine)

Clinical Management Strategies for Coronary Artery Disease and Revascularization

edited by

Marco Spagnolo

submission deadline 25 Jul 2026 | Viewed by 34 | Submission Open

Keywords: coronary artery disease; coronary revascularization; coronary physiology; coronary imaging; antithrombotic therapy

(This special issue belongs to the Section Cardiovascular Medicine)

Interaction Between Systemic Diseases and Oral Diseases: 2nd Edition

edited by

Henk S. Brand

submission deadline 25 Jul 2026 | Viewed by 31 | Submission Open

Keywords: medical dental interaction; saliva; xerostomia; diagnostics; inflammatory bowel disease; cancer survivors; dental erosion; Sjö gren’ s disease; liver transplantation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Obstructive Sleep Apnea: Advances in Clinical Diagnosis and Management

edited by

Gonzalo Labarca

submission deadline 25 Jul 2026 | Viewed by 29 | Submission Open

Keywords: obstructive sleep apnea; sleep disorder breathing; central apnea; apnea– hypopnea index; precision medicine

(This special issue belongs to the Section Respiratory Medicine)

Cardiac Electrophysiology: New Insights and Future Directions: 2nd Edition

edited by

Michael Spartalis

submission deadline 25 Jul 2026 | Viewed by 16 | Submission Open

Keywords: catheter ablation; pulsed-field ablation; conduction-system pacing; arrhythmias; implantable cardiac devices; leadless pacing; mapping technologies; digital health; artificial intelligence; sudden cardiac death

(This special issue belongs to the Section Cardiology)

Updates in the Diagnosis, Imaging, and Treatment of Retinal and Macular Diseases

edited by

Makoto Inoue

submission deadline 26 Jul 2026 | Viewed by 59 | Submission Open

Keywords: retinal diseases; macular degeneration; diagnostic imaging; OCT/OCTA; artificial intelligence; deep learning; clinical ophthalmology; gene therapy; treatment innovations

(This special issue belongs to the Section Ophthalmology)

Clinical Diagnosis and Treatment Strategies in Sjogren's Disease (SjD)

edited by

Nancy L. Carteron

Ava Wu

and Nancy McNamara

submission deadline 29 Jul 2026 | Viewed by 22 | Submission Open

Keywords: Sjogren; Sjogren’ s disease; lymphocytic tissue infiltration; interdisciplinary care; pathogenesis; caries; corneal erosions; autoimmunity; lymphoproliferative (or lymphoma)

(This special issue belongs to the Section Immunology & Rheumatology)

Improving Outcomes in Systemic Lupus Erythematosus: Latest Advances and Prospects in Relation to Comorbidity, Damage, and Quality of Life

edited by

Oshrat E. Tayer-Shifman

and Shaye Kivity

submission deadline 30 Jul 2026 | Viewed by 81 | Submission Open

Keywords: systemic lupus erythematosus; comorbidities; outcome measures; damage accrual; quality of life; cognitive im-pairment; infections and vaccination; treat-to-target; digital biomarkers

(This special issue belongs to the Section Immunology & Rheumatology)

Clinical Insights and Applications in Cardiac Electrophysiology

edited by

Alberto Preda

and Fabrizio Guarracini

submission deadline 30 Jul 2026 | Viewed by 53 | Submission Open

Keywords: atrial fibrillation; catheter ablation; transvenous lead extraction; left atrial appendage occlusion; heart failure; subcutaneous ICD; extravascular ICD; conduction system pacing; cardiac electrophysiology; cardiac rhythm disorders; arrhythmia mapping; supraventricular arrhythmias; ventricular arrhythmias; cardiomyopathies; implantable cardiac devices; minimally invasive devices; left atrial appendage closure; personalized arrhythmia care; clinical management; innovative electrophysiological techniques

(This special issue belongs to the Section Cardiology)

Endoscopic Management of Pancreaticobiliary Diseases

edited by

Kamran Ayub

submission deadline 30 Jul 2026 | Viewed by 46 | Submission Open

Keywords: pancreaticobiliary endoscopy; endoscopic ultrasound (EUS); endoscopic retrograde cholangiopancreatography (ERCP); biliary drainage; gallbladder drainage; lumen-opposing metal stents; cholangioscopy; pancreatoscopy; confocal laser endomicroscopy; pancreatic cysts; molecular diagnostics; lithotripsy (electrohydraulic and laser); radiofrequency ablation (RFA); photodynamic therapy (PDT); pancreatic and biliary tumors; interventional endoscopy; altered anatomy access; diagnostic and therapeutic endoscopy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Integrated Assessment and Management of Heart Failure Syndromes

edited by Damiano Magrì and Emiliano Fiori

submission deadline 30 Jul 2026 | Viewed by 42 | Submission Open

Keywords: heart failure; functional capacity; multimodality assessment; advanced imaging; coronary and structural interventions; device therapies

(This special issue belongs to the Section Cardiology)

Innovations in Elbow and Shoulder Surgery: Techniques, Outcomes, and Rehabilitation

edited by Andrea Celli

submission deadline 30 Jul 2026 | Viewed by 25 | Submission Open

Keywords: orthopedic; elbow surgery; shoulder surgery; infection; nonunion; malunion; ligaments injuries; tendon injuries; el-bow and shoulder replacement; arthroscopy

(This special issue belongs to the Section Orthopedics)

Effects of Exercise Training on Physiological and Functional Outcomes in Age and Frailty

edited by

Dihogo Gama de Matos

and

Rodrigo Villar

submission deadline 30 Jul 2026 | Viewed by 24 | Submission Open

Keywords: exercise training ; older adults ; frailty ; cardiovascular system ; autonomic system ; quality of life ; healthy aging ; functional capacity

(This special issue belongs to the Section Geriatric Medicine)

Displaying special issue 1451-1500 on page 30 of 32.

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