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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Updates on Acromegaly

edited by

Marek Bolanowski

, Jowita Halupczok-Żyła, Aleksandra Gilis-Januszewska and Przemysław Witek

submission deadline 10 Apr 2027 | 1 articles | Viewed by 1786 | Submission Open

Keywords: acromegaly; GH; IGH-1; growth hormone-secreting pituitary adenoma; pituitary adenoma

(This special issue belongs to the Section Endocrinology & Metabolism)

Current Challenges and Perspectives in Aortic Valve Replacement

edited by

Leonardo Guimaraes

, Quentin Fischer and David Del Val

submission deadline 10 Apr 2027 | 1 articles | Viewed by 1720 | Submission Open

Keywords: aortic valve replacement; transcatheter aortic valve implantation (TAVI); surgical aortic valve replacement; prosthesis–patient mismatch; structural heart disease; heart team; valve durability; coronary access; valve-in-valve

(This special issue belongs to the Section Cardiovascular Medicine)

Crohn’s Disease: Ongoing Challenges and Future Directions in Diagnosis and Monitoring

edited by Laura Maria Minordi and

Lucrezia Laterza

submission deadline 10 Apr 2027 | Viewed by 114 | Submission Open

Keywords: Crohn’s disease; imaging; endoscopy; complications; advanced therapies; radiomic; surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in Functional Diagnostics and Physiotherapy of Musculoskeletal Disorders

edited by

Małgorzata Stefańska

and

Łukasz Pawik

submission deadline 10 Apr 2027 | Viewed by 91 | Submission Open

Keywords: functional diagnostics; physiotherapy; rehabilitation; musculoskeletal system; functional assessment; gait analysis; movement biomechanics; postural control; postural stability; muscle strength; muscle tone; digital technologies in rehabilitation; objective measurement methods

(This special issue belongs to the Section Clinical Rehabilitation)

Clinical Advances in Swallowing Disorders: Advancing Measurement Science in Dysphagia

edited by Phoebe Macrae

submission deadline 10 Apr 2027 | Viewed by 43 | Submission Open

Keywords: dysphagia; measurement science; outcome measurement; psychometrics; swallowing physiology; instrumental assessment; quantitative measurement; measurement methodology; biomarkers; patient-reported outcome measures (PROMs); artificial intelligence

(This special issue belongs to the Section Otolaryngology)

Advances in Musculoskeletal Rehabilitation and Functional Movement

edited by

Sanghee Park

submission deadline 13 Apr 2027 | 5 articles | Viewed by 5972 | Submission Open

Keywords: corrective exercise; functional training; biomechanics; resistance training; movement impairment; electromyography; muscle activation; musculoskeletal rehabilitation

(This special issue belongs to the Section Clinical Rehabilitation)

Hypertension and Cardiovascular Disease: Clinical Updates and Perspectives: 2nd Edition

edited by

Valeria Visco

and Nicola Virtuoso

submission deadline 15 Apr 2027 | 7 articles | Viewed by 5898 | Submission Open

Keywords: hypertension management; cardiovascular risk assessment; novel antihypertensive therapies; hypertension in pregnancy; hypertensive emergencies; cardiovascular disease prevention; pharmacological interventions for cardiovascular disease

(This special issue belongs to the Section Cardiovascular Medicine)

New Perspectives and Innovations in Critical Illness

edited by

Francesco Alessandri

and

Giovanni Giordano

submission deadline 15 Apr 2027 | 3 articles | Viewed by 2318 | Submission Open

Keywords: critical illness; intensive care; ECMO; hemodynamic management; shock physiology; cardiovascular support

(This special issue belongs to the Section Intensive Care)

Future-Proof Care for Patients with Kidney Stones

edited by

Stijn Roemeling

and Oliver Wiseman

submission deadline 15 Apr 2027 | 2 articles | Viewed by 1194 | Submission Open

Keywords: effectiveness; resilience; prevention; care pathways; urolithiasis; kidney stones; PCNL; URS; ESWL; quality of life

(This special issue belongs to the Section Nephrology & Urology)

Retinal Diseases: Recent Advances in Diagnosis and Treatment—2nd Edition

edited by Dario Giorgio and Dario Pasquale Mucciolo

submission deadline 15 Apr 2027 | 1 articles | Viewed by 792 | Submission Open

Keywords: retinal diseases; retinal degeneration; macular degeneration; OCT; retinal imaging

(This special issue belongs to the Section Ophthalmology)

Advances in Retinal Diseases—Mechanisms, Diagnostics, and Emerging Therapies, 2nd Edition

edited by

Minzhong Yu

submission deadline 15 Apr 2027 | 1 articles | Viewed by 470 | Submission Open

Keywords: inherited retinal diseases; age-related macular degeneration; diabetic retinopathy; multimodal retinal imaging; treatment

(This special issue belongs to the Section Ophthalmology)

Clinical Updates on Reproductive Endocrinology in Children and Adolescents

edited by

Charikleia Stefanaki

submission deadline 15 Apr 2027 | Viewed by 458 | Submission Open

Keywords: reproductive endocrinology; adolescents; male hypogonadism; female hypogonadism; reproductive metabolism; PCOS; POF; receptor abnormalities; menstrual cycle; transgender health; CAH; ovaries; gonads; hormones; sex development; amenorrhea; estrogen resistance; androgen resistance; teen pregnancy; oncology; preservation of fertility

(This special issue belongs to the Section Clinical Pediatrics)

Revisional and Conversion Bariatric Surgery: Safety and Outcomes

edited by Jerry Dang and Thomas H. Shin

submission deadline 15 Apr 2027 | Viewed by 285 | Submission Open

Keywords: revisional bariatric surgery; conversion surgery; weight recurrence; surgical outcomes; sleeve gastrectomy; roux-en-y gastric bypass; post-bariatric complications; GERD

(This special issue belongs to the Section General Surgery)

Gene Correction and Regenerative Therapies for Inherited Retinal Diseases: Clinical Perspectives

edited by Sushma Kalmodia

submission deadline 15 Apr 2027 | Viewed by 278 | Submission Open

Keywords: gene therapy; AAV; IRD; retinal organoids; RPE

(This special issue belongs to the Section Ophthalmology)

Contemporary Advances in Cardiomyopathies: Diagnosis, Risk Assessment and Therapeutic Innovation

edited by Maria Cristina Carella and

Andrea Igoren Guaricci

submission deadline 15 Apr 2027 | Viewed by 138 | Submission Open

Keywords: cardiomyopathies; cardiovascular genetics; cardiac magnetic resonance; advanced cardiovascular imaging; heart failure; sports cardiology; precision medicine

(This special issue belongs to the Section Cardiology)

The Role of Non-Radiological Imaging in Interventional Arrhythmology Procedures: Challenges and New Perspectives

edited by

Roberto Floris

and Stefano Bandino

submission deadline 15 Apr 2027 | Viewed by 111 | Submission Open

Keywords: cardiac interventional arrhythmology; cardiac ultrasound; echocardiography; near-zero x-ray; electroanatomical mapping; intracardiac echocardiography; thoracic ultrasound

(This special issue belongs to the Section Cardiology)

Sports Injury Rehabilitation and Clinical Recovery Strategies

edited by

Magdalena Hagner-Derengowska

submission deadline 15 Apr 2027 | Viewed by 98 | Submission Open

Keywords: sports injury; rehabilitation; recovery; return to sport; return to performance; mechanobiology; load management; neuromuscular control; digital health; injury prevention

(This special issue belongs to the Section Sports Medicine)

Biomarkers in Cancer Diagnosis and Prognosis

edited by Gina Gheorghe

submission deadline 15 Apr 2027 | Viewed by 92 | Submission Open

Keywords: cancer biomarkers; cancer diagnosis; cancer prognosis; liquid biopsy; precision oncology; tumor microenvironment; treatment response; personalized medicine

(This special issue belongs to the Section Oncology)

Cardiac Arrest: From Prevention to Survivorship—Advancing the Chainmail of Survival

edited by

Sebastian Schnaubelt

submission deadline 16 Apr 2027 | Viewed by 234 | Submission Open

Keywords: cardiac arrest; cardiopulmonary resuscitation (CPR); emergency medicine; emergency department; critical care; basic life support (BLS); advanced life support (ALS); chain of survival; chainmail of survival

(This special issue belongs to the Section Emergency Medicine)

Challenges in Diagnosis and Treatment of Infertility—2nd Edition

edited by Konstantinos A. Zikopoulos

submission deadline 20 Apr 2027 | 7 articles | Viewed by 28877 | Submission Open

Keywords: fertility; regeneration; age-related infertility; preimplantation diagnosis; precision assessment; individualized fertility needs; clinical diagnosis; in vitro fertilization

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Pancreatic Disorder, Pancreatitis, and Pancreatic Cancer: Interconnections, Clinical Challenges, and Therapeutic Advances

edited by

Cristian George Ţieranu

and

Adrian Saftoiu

submission deadline 20 Apr 2027 | 3 articles | Viewed by 10207 | Submission Open

Keywords: pancreatic disorder; pancreatitis; pancreatic cancer; translational research; diagnosis; treatment

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Kidney Transplantation: State-of-the-Art Knowledge

edited by

Georgios Koimtzis

, Georgios Geropoulos and Kyriakos Psarras

submission deadline 20 Apr 2027 | 3 articles | Viewed by 5813 | Submission Open

Keywords: kidney transplantation; end-stage renal disease; immunosuppression; organ donation; graft survival; graft rejection

(This special issue belongs to the Section Nephrology & Urology)

Sepsis and Septic Shock: Diagnosis, Treatment, and Prognosis

edited by Luigi Carbone and Daniela Pugliese

submission deadline 20 Apr 2027 | 6 articles | Viewed by 5530 | Submission Open

Keywords: sepsis; septic shock; diagnosis and screening tools; risk stratification; machine learning; advanced therapies

(This special issue belongs to the Section Intensive Care)

Hidradenitis Suppurativa: Clinical Diagnosis, Treatment, and Management

edited by Piotr K. Krajewski

submission deadline 20 Apr 2027 | 5 articles | Viewed by 4763 | Submission Open

Keywords: hidradenitis suppurativa; acne inversa; clinical diagnosis; disease severity assessment; biologic therapy; surgical management; comorbidities; quality of life; multidisciplinary care; real world evidence

(This special issue belongs to the Section Dermatology)

New Clinical Advances in Chronic Asthma—2nd Edition

edited by Vitaliano Nicola Quaranta

submission deadline 20 Apr 2027 | 4 articles | Viewed by 4753 | Submission Open

Keywords: chronic asthma; breathlessness; coughing; inhaled corticosteroids (ICS); long-acting beta-agonists (LABAs); personalized treatment; chronic rhinosinusitis; nasal polyps; bronchiectasis; endotypes; oral corticosteroids

(This special issue belongs to the Section Respiratory Medicine)

Non-Pharmacological Therapies and Exercise Interventions in Clinical Populations

edited by

Jorge Sánchez-Infante

submission deadline 20 Apr 2027 | 5 articles | Viewed by 4474 | Submission Open

Keywords: non-pharmacological interventions; physiotherapy approaches; physical activity; acute and chronic diseases; acute and chronic pain

(This special issue belongs to the Section Clinical Rehabilitation)

Clinical Outcomes of Glaucoma Surgery: Visual Acuity, Effectiveness and Quality of Life

edited by

Gloria Roberti

and

Manuele Michelessi

submission deadline 20 Apr 2027 | 6 articles | Viewed by 4032 | Submission Open

Keywords: glaucoma surgery; visual acuity; intraocular pressure; surgical outcomes; trabeculectomy; microinvasive glaucoma surgery; postoperative complications; functional vision

(This special issue belongs to the Section Ophthalmology)

Infectious Diseases and Host Responses: Clinical, Immunological, and Outcome-Orientated Perspectives

edited by

Nicoleta Negruț

submission deadline 20 Apr 2027 | 3 articles | Viewed by 3837 | Submission Open

Keywords: microbiology; infection; resistance; epidemiology; microbiome; prevention; therapy

(This special issue belongs to the Section Infectious Diseases)

Anesthesia and Intensive Care: Clinical Practices and Prospects

edited by

Jungchan Park

submission deadline 20 Apr 2027 | 4 articles | Viewed by 3713 | Submission Open

Keywords: artificial intelligence; clinical decision support; perioperative risk stratification; perioperative patient safety; hemodynamic optimization

(This special issue belongs to the Section Intensive Care)

Clinical Therapeutic Advances of Mitral Regurgitation

edited by Angelo Squeri

submission deadline 20 Apr 2027 | 4 articles | Viewed by 3502 | Submission Open

Keywords: mitral regurgitation; mitral valve prolapse; cardiovascular interventions; heart surgery; echocardiography; mag-netic resonance imaging; computed tomography

(This special issue belongs to the Section Cardiovascular Medicine)

Cardiovascular Prevention and Epidemiology: Innovations and Insights Bridging Research and Practice for Effective Risk Reduction

edited by

Pasquale Palmiero

and Maria Maiello

submission deadline 20 Apr 2027 | 5 articles | Viewed by 3494 | Submission Open

Keywords: cardiovascular prevention; risk reduction; epidemiology; innovations; risk stratification; population health

(This special issue belongs to the Section Cardiovascular Medicine)

Enhancing and Rehabilitation of Gait and Mobility in Chronic Stroke

edited by

Maria-Arantzazu Ruescas-Nicolau

Marco Iosa

and

María Luz Sánchez-Sánchez

submission deadline 20 Apr 2027 | 1 articles | Viewed by 3470 | Submission Open

Keywords: chronic stroke; gait rehabilitation; mobility; physical therapy; technology-assisted interventions; assessment

(This special issue belongs to the Section Clinical Neurology)

Advances in the Diagnosis and Management of Age-Related Macular Degeneration: 3rd Edition

edited by Tsutomu Yasukawa

submission deadline 20 Apr 2027 | 4 articles | Viewed by 3189 | Submission Open

Keywords: age-related macular degeneration; angiography; anti-vascular endothelial growth factor therapy; geographic atrophy; macular neovascularization; multimodal imaging; ophthalmology; optical coherence tomography; photodynamic therapy; retinal pigment epithelium

(This special issue belongs to the Section Ophthalmology)

Orthopaedic Trauma and Bone Healing: Recent Advances and Future Perspectives

edited by Gheorghe Tomoaia and Daniel Oltean-Dan

submission deadline 20 Apr 2027 | 4 articles | Viewed by 2574 | Submission Open

Keywords: orthopaedic trauma; fractures; minimally invasive fixation; bone healing; biomaterials; periprosthetic fractures; artificial intelligence; rehabilitation; complications; orthopaedic surgery

(This special issue belongs to the Section Orthopedics)

Advances in Cardiac Surgery: Techniques, Outcomes, and Innovations

edited by

Marius-Mihai Harpa

, Horatiu Suciu and

Emil Marian Arbanasi

submission deadline 20 Apr 2027 | 5 articles | Viewed by 2547 | Submission Open

Keywords: endoscopic cardiac surgery; minimally invasive cardiac surgery; MIMS; mini-AVR; MIDCAB; TCRAT; LVAD; heart transplant; congenital heart disease

(This special issue belongs to the Section Cardiology)

Clinical Advances in Geriatric Acute Care: Multimorbidity, Frailty, and Integrated Diagnostics

edited by

Nicoletta Cerundolo

and

Carmine Siniscalchi

submission deadline 20 Apr 2027 | 4 articles | Viewed by 2523 | Submission Open

Keywords: geriatric medicine; frailty; multidimensional assessment; lung ultrasound; point-of-care ultrasound; acute care of older adults; transitional care

(This special issue belongs to the Section Geriatric Medicine)

Endocrine Surgery: Current Treatment and Future Options

edited by Pietro Princi and

Julia Staubitz-Vernazza

submission deadline 20 Apr 2027 | 1 articles | Viewed by 2418 | Submission Open

Keywords: endocrine surgery; thyroid surgery; parathyroid surgery; adrenal gland surgery; neuroendocrine neoplasms; thyroid cancer; thyroid cancer treatment; surgical endocrinology; robotic endocrine surgery; laparoscopic adrenalectomy; ret-roperitoneoscopic adrenalectomy; parathyroidectomy; benign thyroid disease; thyroid ablation

(This special issue belongs to the Section General Surgery)

Advances in the Management of Cervical Spine Trauma

edited by

Jong-Beom Park

and

Sung-kyu Kim

submission deadline 20 Apr 2027 | 3 articles | Viewed by 2407 | Submission Open

Keywords: cervical spine trauma; cervical fracture; high cervical injury; subaxial injury; surgical management; occipitocervical fusion; C1 fracture; C2 fracture; spinal stability; trauma imaging; spinal cord injury; neurological outcome

(This special issue belongs to the Section Orthopedics)

Advances in Trauma and Orthopedic Surgery: 3rd Edition

edited by

Christian von Rüden

submission deadline 20 Apr 2027 | 3 articles | Viewed by 2205 | Submission Open

Keywords: trauma; fracture; fracture fixation; osteosynthesis; biomechanics; bone; approach; nonunion; joint replacement; outcome

(This special issue belongs to the Section Orthopedics)

Clinical Updates and Perspectives in Atrial Fibrillation

edited by Riyaz Somani and

Ibrahim Antoun

submission deadline 20 Apr 2027 | 3 articles | Viewed by 2151 | Submission Open

Keywords: atrial fibrillation; catheter ablation; risk prediction; stroke prevention; digital health and artificial intelligence

(This special issue belongs to the Section Cardiology)

From Clinical Diagnosis to Effective Treatment of Cardiomyopathy

edited by

Sanjay Sivalokanathan

and

Łukasz A. Małek

submission deadline 20 Apr 2027 | 2 articles | Viewed by 2133 | Submission Open

Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathy; non-ischemic cardiomyopathy; cardiac MRI; PET/CT; PET/MRI; cardiac imaging; sudden cardiac death

(This special issue belongs to the Section Cardiology)

Heart Failure and Transplant Cardiology: Latest Advances and Prospects

edited by Monika Budnik

submission deadline 20 Apr 2027 | 4 articles | Viewed by 2000 | Submission Open

Keywords: heart failure; heart transplantation; bridge to transplant; mechanical circulatory support; cardiomyopathies

(This special issue belongs to the Section Cardiology)

Spine Surgery and Postoperative Management

edited by Mitchell K. Ng

submission deadline 20 Apr 2027 | 3 articles | Viewed by 1796 | Submission Open

Keywords: spine surgery; perioperative care; enhanced recovery after surgery (ERAS); multimodal analgesia; opioid-sparing strategies; neuromonitoring; perioperative optimization

(This special issue belongs to the Section Orthopedics)

Diagnosis and Clinical Management in Hematologic Oncology

edited by Sunil Lakhwani and José María Raya-Sánchez

submission deadline 20 Apr 2027 | 3 articles | Viewed by 1737 | Submission Open

Keywords: hematologic malignancies; lymphoma; multiple myeloma; acute leukemia; myeloproliferative neoplasms; molecular diagnostics; targeted therapy; immunotherapy; prognostic biomarkers; clinical management

(This special issue belongs to the Section Hematology)

New Developments and Challenges in Assisted Reproductive Technology

edited by

Shuqin Wei

and

Justin Tan

submission deadline 20 Apr 2027 | 1 articles | Viewed by 1665 | Submission Open

Keywords: assisted reproductive technology; in vitro fertilization; clinical protocols and innovations; embryo selection and evaluation; ethnicity and reproductive outcomes; live birth; cryopreservation and fertility preservation; maternal and offspring health outcomes; global perspectives in reproductive medicine

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Applications and Surgical Integration of Advanced Ophthalmic Imaging

edited by Katarzyna Nowomiejska

submission deadline 20 Apr 2027 | 2 articles | Viewed by 1658 | Submission Open

Keywords: ophthalmic imaging; retina; intraoperative OCT; personalized treatment; clinical applications

(This special issue belongs to the Section Ophthalmology)

Electrotherapy and Electrodiagnostic in Modern Rehabilitation Medicine: Current Evidence, Clinical Applications, and Future Perspectives

edited by Cristina Octaviana Daia

submission deadline 20 Apr 2027 | 1 articles | Viewed by 1630 | Submission Open

Keywords: electrotherapy; physical and rehabilitation medicine; rehabilitation technologies; neurorehabilitation; cancer rehabilitation; electromyography; nerve conduction studies; musculoskeletal ultrasound; photobiomodula-tion; neuromuscular electrical stimulation; therapeutic ultrasound; extracorporeal shockwave therapy; electromagnetic field therapy; TECAR therapy

(This special issue belongs to the Section Clinical Rehabilitation)

Endometriosis: Advances in Diagnosis, Treatment, and Long-Term Outcomes

edited by

Francesco Martire

submission deadline 20 Apr 2027 | 2 articles | Viewed by 1551 | Submission Open

Keywords: endometriosis; diagnosis and biomarkers; medical and surgical treatment; fertility and reproductive outcomes; pain management; quality of life; long-term follow-up

(This special issue belongs to the Section Obstetrics & Gynecology)

Complications of Laparoscopic Cholecystectomy: Surgical Outcomes and Clinical Challenges

edited by

Roberto Cirocchi

submission deadline 20 Apr 2027 | 1 articles | Viewed by 1459 | Submission Open

Keywords: laparoscopic cholecystectomy; bile duct injury; management of intraoperative injuries; surgical outcomes; postoperative infections

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Esophageal and Upper Gastrointestinal Surgery: Clinical Advances and Practical Updates

edited by

Pedro Serralheiro

and Peter Grimminger

submission deadline 20 Apr 2027 | 2 articles | Viewed by 1273 | Submission Open

Keywords: esophageal cancer; gastric cancer; upper GI surgery; surgical oncology; benign upper GI surgery; surgical innovation; surgical outcomes; surgical guidelines; robotic surgery; minimally invasive surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Displaying special issue 1201-1250 on page 25 of 30.

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