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Enhancing and Rehabilitation of Gait and Mobility in Chronic Stroke

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".

Deadline for manuscript submissions: 20 August 2026 | Viewed by 1393

Special Issue Editors


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Guest Editor
Physiotherapy in Motion, Multispeciality Research Group (PTinMOTION), Department of Physiotherapy, Faculty of Physiotherapy, University of Valencia, Gascó Oliag n 5, 46010 Valencia, Spain
Interests: chronic stroke; gait rehabilitation mobility; physical therapy; technology-assisted interventions; assessment
Laboratory for the Study of Mind and Action in Rehabilitation Technologies—Smart Lab, Santa Lucia Foundation IRCCS, Via Ardeatina 306, 00179 Rome, Italy
Interests: neuroscience; neurorehabilitation; motor control; neuropsychology; psychometry
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Guest Editor Assistant
Physiotherapy in Motion, Multispeciality Research Group (PTinMOTION), Department of Physiotherapy, Faculty of Physiotherapy, University of Valencia, Gascó Oliag n 5, 46010 Valencia, Spain
Interests: stroke rehabilitation; neurorehabilitation; physiotherapy; gait analysis

Special Issue Information

Dear Colleagues,

Chronic stroke survivors face persistent impairments that lead to reduced mobility and quality of life. Furthermore, these individuals are less active than their peers, with restricted community participation. Nevertheless, in the chronic phase, meaningful improvements in mobility are possible through high-intensity, task-specific and personalized rehabilitation. Traditional approaches (task-specific practice, strengthening exercises, aerobic conditioning, balance training and neuromuscular re-education) and technology-assisted interventions (robotic gait trainers, body-weight–supported treadmill training, functional electrical stimulation, virtual reality and wearable sensors) have shown efficacy. However, optimal protocols and long-term effects require further investigation. This Special Issue invites manuscripts exploring innovative interventions to enhance gait and mobility in chronic stroke populations.

Dr. Maria-Arantzazu Ruescas-Nicolau
Dr. Marco Iosa
Guest Editors

Dr. María Luz Sánchez-Sánchez
Guest Editor Assistant

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Keywords

  • chronic stroke
  • gait rehabilitation
  • mobility
  • physical therapy
  • technology-assisted interventions
  • assessment

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Published Papers (1 paper)

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19 pages, 2190 KB  
Systematic Review
Constraint-Induced Movement Therapy in the Rehabilitation of Adults After Stroke: An Umbrella Review
by José Conchillo-Liria, Iván Cavero-Redondo, Alicia Saz-Lara, Nerea Moreno-Herraiz, Candela Calvo-Utrilla, Ana González-Collado and Iris Otero-Luis
J. Clin. Med. 2026, 15(6), 2451; https://doi.org/10.3390/jcm15062451 - 23 Mar 2026
Viewed by 1126
Abstract
Background/Objectives: Stroke is among the leading causes of disability in adults, as hemiparesis affects motor function and daily activities. Constraint-induced movement therapy (CIMT) has proven effective in functional recovery through intensive use of the affected limb. This study aimed to assess the [...] Read more.
Background/Objectives: Stroke is among the leading causes of disability in adults, as hemiparesis affects motor function and daily activities. Constraint-induced movement therapy (CIMT) has proven effective in functional recovery through intensive use of the affected limb. This study aimed to assess the impact of CIMT on upper limb (UL) rehabilitation in stroke patients, with a focus on motor recovery, integration into activities of daily living (ADLs), and overcoming clinical implementation barriers. Methods: A systematic review was conducted by searching PubMed, Scopus, and Web of Science from their inception to March 2026. Systematic reviews and meta-analyses evaluating the effectiveness of CIMT in adult patients after stroke were included. The outcome variables included motor function, movement quality, independence in ADLs, and quality of life (QoL). Results: Twenty-five systematic reviews and sixteen meta-analyses were included. The participants were adults who had suffered a stroke at acute, subacute, or chronic stages and were aged between 18 and 95 years. With respect to upper limb motor function, ten studies reported statistically significant results in favor of CIMT. With respect to ADLs, four studies reported significant differences in favor of CIMT, with strong effects in intensive interventions. With respect to QoL, three studies reported significant improvements after the intervention. Conclusions: The results of this umbrella review support the effectiveness of CIMT in UL rehabilitation after stroke, especially in the subacute and chronic phases. CIMT, alone or in combination with adjuvant therapies, contributes to improving motor function, independence in ADLs, and QoL in patients. Full article
(This article belongs to the Special Issue Enhancing and Rehabilitation of Gait and Mobility in Chronic Stroke)
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