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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Endometriosis: Diagnosis and Treatment submission deadline 25 Jul 2026 | 3 articles | Viewed by 4894 | Submission Open
Keywords: endometriosis; diagnosis; video laparoscopy with and without robotic assistance; chronic pelvic pain; fertility preservation; minimally invasive surgery; biomarkers; artificial intelligence in endometriosis, adenomyosis, and adenomyoma care; multidisciplinary care; personalized medicine
(This special issue belongs to the Section Obstetrics & Gynecology)
Advancements in Individualized Plastic and Reconstructive Surgery: Second Edition
edited by , Peter Niclas Broer and Denis C. Ehrl
submission deadline 25 Jul 2026 | 4 articles | Viewed by 4298 | Submission Open
Keywords: patient-specific reconstructive procedures; microsurgical precision techniques; autologous tissue transplantation; digital imaging and customization; biomaterials in reconstructive surgery; tissue engineering for plastic reconstruction; flap surgery innovations; personalized cleft surgery; personalized aesthetic surgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Revolutionizing Neurosurgery: Cutting-Edge Techniques and Innovations
edited by
submission deadline 25 Jul 2026 | 3 articles | Viewed by 4027 | Submission Open
Keywords: neuroendovascular surgery; neuroimaging; neurosurgery; neuroendoscopic surgery
(This special issue belongs to the Section Clinical Neurology)
Obstructive Sleep Apnea: Advances in Clinical Diagnosis and Management
edited by
submission deadline 25 Jul 2026 | 5 articles | Viewed by 3672 | Submission Open
Keywords: obstructive sleep apnea; sleep disorder breathing; central apnea; apnea–hypopnea index; precision medicine
(This special issue belongs to the Section Respiratory Medicine)
Diagnosis and Treatment of Aortic Dissection: Experts' Views
edited by Marja K Hedman and Annastiina Husso
submission deadline 25 Jul 2026 | 3 articles | Viewed by 3225 | Submission Open
Keywords: aortic diseases; aortic type A dissection; aortic growth rate; aortic length; aortic imaging
(This special issue belongs to the Section Cardiology)
Innovations in Spine Care: Advancing Clinical Solutions and Emerging Technologies
edited by , , Gianluca Vadalà and Vincenzo Denaro
submission deadline 25 Jul 2026 | 2 articles | Viewed by 3052 | Submission Open
Keywords: artificial intelligence; AI; minimally invasive spine surgery; MIS; endoscopic spine surgery; intervertebral disc regeneration; precision medicine; spine care; spine fusion; osteobiologics
(This special issue belongs to the Section Orthopedics)
Cardiothoracic and Vascular Anesthesia—Clinical Management and Challenges
edited by Marko Zdravković and
submission deadline 25 Jul 2026 | 3 articles | Viewed by 2946 | Submission Open
Keywords: cardiac anesthesia; thoracic anesthesia; vascular anesthesia; innovation; perioperative medicine; healthcare; outcomes; challenges
(This special issue belongs to the Section Anesthesiology)
Sleep Disorders: Current Research and Future Directions—Second Edition
edited by Martina Vendrame
submission deadline 25 Jul 2026 | 4 articles | Viewed by 2636 | Submission Open
Keywords: obstructive sleep apnea; parasomnia; idiopathic hypersomnia; periodic limb movement disorder; periodic limb move-ment of sleep
(This special issue belongs to the Section Clinical Neurology)
Clinical Advances in Scleral Lenses: New Insights in Lens Fitting and Customization
edited by and
submission deadline 25 Jul 2026 | 1 articles | Viewed by 2179 | Submission Open
Keywords: scleral lenses; scleral lens customization; higher-order aberrations; scleral lens optics; corneoscleral profilometry; keratoconus; ocular surface diseases; dry eye; wavefront-guided correction
(This special issue belongs to the Section Ophthalmology)
Recent Clinical Advances in Reconstructive Urology and Prosthetic Surgery
edited by Elisa Berdondini and
submission deadline 25 Jul 2026 | 1 articles | Viewed by 2159 | Submission Open
Keywords: reconstructive urology; penile prosthesis; artificial urinary sphincter; urethral stricture; reconstructive surgery; minimally invasive procedures
(This special issue belongs to the Section Nephrology & Urology)
New Advances in Hip and Knee Reconstructive Surgery: 2nd Edition
edited by Senthil Sambandam
submission deadline 25 Jul 2026 | 2 articles | Viewed by 1474 | Submission Open
Keywords: knee; hip; joint arthroplasty; minimally invasive surgery; revision arthroplasty; periprosthetic joint infection; muscle injury; joint alignment; surgical advances; osteotomy; fracture; robotic-assisted surgery; perioperative optimization; telerehabilitation; aseptic loosening
(This special issue belongs to the Section Orthopedics)
Hearing Loss Management in Children: Guidelines and Interventions
edited by Lone Percy-Smith
submission deadline 25 Jul 2026 | 1 articles | Viewed by 1248 | Submission Open
Keywords: early intervention for populations with HL; emerging new generations of persons with HL; quality assurance of interventions for populations with HL; self-assessments of quality of life
(This special issue belongs to the Section Clinical Pediatrics)
High-Risk Pregnancy Management: From Prenatal Care to Postpartum Outcomes
edited by
submission deadline 25 Jul 2026 | 1 articles | Viewed by 1178 | Submission Open
Keywords: high-risk pregnancy; prenatal care; postpartum outcomes; postpartum mental health; birth trauma; AI in obstetrics; medico-legal liability; equity & culturally safe care; indigenous and rural/remote care; EMR-enabled decision support; quality trend monitoring; maternal morbidity and mortality; perinatal morbidity; standardized care bundles & pathways
(This special issue belongs to the Section Obstetrics & Gynecology)
Further Advances in Electrocardiography, Cardiac Arrhythmias, and Arrhythmogenic Disorders: 2nd Edition
edited by
submission deadline 25 Jul 2026 | 1 articles | Viewed by 977 | Submission Open
Keywords: electrocardiography; cardiac arrhythmias; genetics; cardiac pacing; implantable cardioverter defibrillators; cardiac resynchronization therapy; magnetic resonance imaging; catheter ablation; arrhythmogenic disorders; channelopathy; cardiomyopathy
(This special issue belongs to the Section Cardiology)
Clinical Management and Update of Aortic Dissection and Aortic Aneurysm Diseases
edited by
submission deadline 25 Jul 2026 | 1 articles | Viewed by 962 | Submission Open
Keywords: aortic aneurysm; aortic dissection; aortic surgery; endovascular procedures
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Management Strategies for Coronary Artery Disease and Revascularization
edited by
submission deadline 25 Jul 2026 | 1 articles | Viewed by 957 | Submission Open
Keywords: coronary artery disease; coronary revascularization; coronary physiology; coronary imaging; antithrombotic therapy
(This special issue belongs to the Section Cardiovascular Medicine)
Novel Prognostic Risk Factors in Acute Coronary Syndrome submission deadline 25 Jul 2026 | 1 articles | Viewed by 813 | Submission Open
Keywords: acute coronary syndrome; risk stratification; biomarkers; cardiovascular imaging; inflammation; genetics; heart–kidney interaction; cardio-pulmonary complications; neurological dysfunction; precision medicine
(This special issue belongs to the Section Cardiology)
Interaction Between Systemic Diseases and Oral Diseases: 2nd Edition
edited by
submission deadline 25 Jul 2026 | 1 articles | Viewed by 653 | Submission Open
Keywords: medical dental interaction; saliva; xerostomia; diagnostics; inflammatory bowel disease; cancer survivors; dental erosion; Sjögren’s disease; liver transplantation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Advances in Hysteroscopic Technology for Gynecological Diseases
edited by Aya Mohr-Sasson and Raanan Meyer
submission deadline 25 Jul 2026 | Viewed by 573 | Submission Open
Keywords: diagnostic hysteroscopy; operative hysteroscopy; uterine sampling; uterine polyp; submucosal fibroid; hysteroscopic dilatation and curettage; hysteroscopic niche repair
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Updates on Transcatheter Structural Heart Disease Interventions
edited by Nazan Puluca and Hendrik Ruge
submission deadline 25 Jul 2026 | 1 articles | Viewed by 431 | Submission Open
Keywords: interventional valve therapy; TAVR; TEER; TMVR; mitral valve; tricuspid valve; coronary access
(This special issue belongs to the Section Cardiology)
Cardiac Electrophysiology: New Insights and Future Directions: 2nd Edition
edited by
submission deadline 25 Jul 2026 | Viewed by 410 | Submission Open
Keywords: catheter ablation; pulsed-field ablation; conduction-system pacing; arrhythmias; implantable cardiac devices; leadless pacing; mapping technologies; digital health; artificial intelligence; sudden cardiac death
(This special issue belongs to the Section Cardiology)
Diagnosis and Treatment of Pleura and Lung: Clinical Advances in Intensive Care
edited by Alen Protić and
submission deadline 25 Jul 2026 | Viewed by 329 | Submission Open
Keywords: thoracic drainage; lung recruitment; lung ultrasound; pleural effusion; pneumothrax; B-line; lung atelectasis
(This special issue belongs to the Section Intensive Care)
Complications Related to Coronary Artery Disease and Secondary Prevention Strategies
edited by Nazanin Rajai
submission deadline 25 Jul 2026 | Viewed by 281 | Submission Open
Keywords: coronary artery disease; complications; secondary prevention; myocardial infarction; cardiovascular risk; heart failure; arrhythmias; imaging; biomarkers; cardiovascular pharmacotherapy
(This special issue belongs to the Section Cardiovascular Medicine)
Recent Advances in Bariatric Surgery submission deadline 25 Jul 2026 | Viewed by 253 | Submission Open
Keywords: bariatric surgery; metabolic surgery; minimally invasive surgery; robotic surgery; endoscopic bariatric procedures; obesity management; type 2 diabetes remission; perioperative care; long-term outcomes; enhanced recovery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Application of Endoscopic Submucosal Dissection in Malignant Gastrointestinal Tumors and Precursors—2nd Edition submission deadline 25 Jul 2026 | Viewed by 224 | Submission Open
Keywords: endoscopy; endoscopic submucosal dissection; endoscopic surgery; laparoscopic surgery; minimally invasive surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Current Advances and Future Perspectives in Cardiac Arrest and Cardiogenic Shock
edited by Giulia Maj
submission deadline 25 Jul 2026 | Viewed by 210 | Submission Open
Keywords: cardiogenic shock; left ventricular unloading; biomarkers; recovery; cardiac arrest
(This special issue belongs to the Section Emergency Medicine)
Updates in the Diagnosis, Imaging, and Treatment of Retinal and Macular Diseases
edited by
submission deadline 26 Jul 2026 | 3 articles | Viewed by 3145 | Submission Open
Keywords: retinal diseases; macular degeneration; diagnostic imaging; OCT/OCTA; artificial intelligence; deep learning; clinical ophthalmology; gene therapy; treatment innovations
(This special issue belongs to the Section Ophthalmology)
Challenges in Diagnosis and Treatment of Infertility—2nd Edition
edited by Konstantinos A. Zikopoulos
submission deadline 27 Jul 2026 | 4 articles | Viewed by 16775 | Submission Open
Keywords: fertility; regeneration; age-related infertility; preimplantation diagnosis; precision assessment; individualized fertility needs; clinical diagnosis; in vitro fertilization
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Heart Valve Surgery: Recent Trends and Future Perspective
edited by Per Nils J.F. Wierup, Johan Sjögren and Nina Hakacova
submission deadline 27 Jul 2026 | 1 articles | Viewed by 867 | Submission Open
Keywords: heart valve; diagnostics; surgery; echocardiography; computer simulation; prediction models
(This special issue belongs to the Section Cardiology)
Inflammatory Bowel Disease: Pathogenesis and Management Strategies
edited by
submission deadline 28 Jul 2026 | 3 articles | Viewed by 4319 | Submission Open
Keywords: inflammatory bowel diseases; ulcerative colitis; Crohn’s disease; biomarkers; risk factors; pharmacology; advanced therapy; endoscopic evaluation and procedures; extraintestinal manifestations; IBD-associated neoplasm
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Diagnosis and Treatment Strategies in Sjogren's Disease (SjD)
edited by , and Nancy McNamara
submission deadline 29 Jul 2026 | Viewed by 352 | Submission Open
Keywords: Sjogren; Sjogren’s disease; lymphocytic tissue infiltration; interdisciplinary care; pathogenesis; caries; corneal erosions; autoimmunity; lymphoproliferative (or lymphoma)
(This special issue belongs to the Section Immunology & Rheumatology)
Mind–Body Connection: The Impact of Mental Health on Physical Well-Being
edited by
submission deadline 30 Jul 2026 | 4 articles | Viewed by 9009 | Submission Open
Keywords: mind–body connection; mental health; well-being; metabolic balance; immune system; chronic medical conditions; body perception; self-image; eating disorders; psychosomatic disorders; psychosomatic medicine; innovative thera-peutic approaches; mindfulness; mind-wandering; integrated healthcare
(This special issue belongs to the Section Mental Health)
Current Advances in General and Regional Anesthesia
edited by Eleni Laou, Eleana Garini and
submission deadline 30 Jul 2026 | 2 articles | Viewed by 5575 | Submission Open
Keywords: anesthesiology; general anesthesia; regional anesthesia; pediatric anesthesia; perioperative medicine; surgery; postoperative outcome; monitoring; analgesia; safety
(This special issue belongs to the Section Anesthesiology)
Endoscopic Management of Pancreaticobiliary Diseases
edited by
submission deadline 30 Jul 2026 | 2 articles | Viewed by 1473 | Submission Open
Keywords: pancreaticobiliary endoscopy; endoscopic ultrasound (EUS); endoscopic retrograde cholangiopancreatography (ERCP); biliary drainage; gallbladder drainage; lumen-opposing metal stents; cholangioscopy; pancreatoscopy; confocal laser endomicroscopy; pancreatic cysts; molecular diagnostics; lithotripsy (electrohydraulic and laser); radiofrequency ablation (RFA); photodynamic therapy (PDT); pancreatic and biliary tumors; interventional endoscopy; altered anatomy access; diagnostic and therapeutic endoscopy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Improving Outcomes in Systemic Lupus Erythematosus: Latest Advances and Prospects in Relation to Comorbidity, Damage, and Quality of Life
edited by and Shaye Kivity
submission deadline 30 Jul 2026 | 2 articles | Viewed by 1403 | Submission Open
Keywords: systemic lupus erythematosus; comorbidities; outcome measures; damage accrual; quality of life; cognitive im-pairment; infections and vaccination; treat-to-target; digital biomarkers
(This special issue belongs to the Section Immunology & Rheumatology)
Effects of Exercise Training on Physiological and Functional Outcomes in Age and Frailty submission deadline 30 Jul 2026 | 1 articles | Viewed by 908 | Submission Open
Keywords: exercise training ; older adults ; frailty ; cardiovascular system ; autonomic system ; quality of life ; healthy aging ; functional capacity
(This special issue belongs to the Section Geriatric Medicine)
Clinical Insights in Preventive Cardiology
edited by and
submission deadline 30 Jul 2026 | 1 articles | Viewed by 846 | Submission Open
Keywords: preventive cardiology; cardiovascular prevention; cardiovascular risk assessment; risk stratification; primary prevention; secondary prevention; exposome; environmental determinants of health; lifestyle modification; digital health; wearable technologies
(This special issue belongs to the Section Cardiology)
Clinical and Laboratory Applications of Artificial Intelligence in Haematology
edited by and Bingwen Eugene Fan
submission deadline 30 Jul 2026 | 1 articles | Viewed by 693 | Submission Open
Keywords: hematology; artificial intelligence/AI; machine learning/ML; innovation; hemostasis; thrombosis; diagnostics; prog-nosis; laboratory automation; clinical decision support; precision medicine; big data; digital pathology
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Clinical Medicine)
Clinical Insights and Applications in Cardiac Electrophysiology
edited by and Fabrizio Guarracini
submission deadline 30 Jul 2026 | Viewed by 380 | Submission Open
Keywords: atrial fibrillation; catheter ablation; transvenous lead extraction; left atrial appendage occlusion; heart failure; subcutaneous ICD; extravascular ICD; conduction system pacing; cardiac electrophysiology; cardiac rhythm disorders; arrhythmia mapping; supraventricular arrhythmias; ventricular arrhythmias; cardiomyopathies; implantable cardiac devices; minimally invasive devices; left atrial appendage closure; personalized arrhythmia care; clinical management; innovative electrophysiological techniques
(This special issue belongs to the Section Cardiology)
Innovations in Elbow and Shoulder Surgery: Techniques, Outcomes, and Rehabilitation
edited by Andrea Celli
submission deadline 30 Jul 2026 | Viewed by 324 | Submission Open
Keywords: orthopedic; elbow surgery; shoulder surgery; infection; nonunion; malunion; ligaments injuries; tendon injuries; el-bow and shoulder replacement; arthroscopy
(This special issue belongs to the Section Orthopedics)
Integrated Assessment and Management of Heart Failure Syndromes
edited by Damiano Magrì and Emiliano Fiori
submission deadline 30 Jul 2026 | Viewed by 253 | Submission Open
Keywords: heart failure; functional capacity; multimodality assessment; advanced imaging; coronary and structural interventions; device therapies
(This special issue belongs to the Section Cardiology)
Molecular Injection Therapy in Orthopedic and Musculoskeletal Disorders: Conservative Approaches and Innovative Treatments
edited by , Paolo Domenico Parchi and Andrea del Chiaro
submission deadline 31 Jul 2026 | 5 articles | Viewed by 6406 | Submission Open
Keywords: injection therapy; conservative approaches; medical devices; collagen; polyribonucleotide; plasma-rich platelets; hyaluronic acids; anti-inflammatory therapy; tendinitis, osteoarthritis, musculoskeletal disorder, pain reduction; regenerative medicine; new clinical approaches; physiotherapy; comparative studies: surgery vs. conservative approaches
(This special issue belongs to the Section Orthopedics)
Catheter Ablation of Atrial Fibrillation: Current Progress and New Challenges
edited by Sorin Stefan Popescu, Roland Richard Tilz and Karl-Heinz Kuck
submission deadline 31 Jul 2026 | 3 articles | Viewed by 6067 | Submission Open
Keywords: atrial fibrillation; novel technologies; pulmonary vein isolation; same-day discharge; pulsed field ablation; cryo-ablation; radiofrequency; safety; efficacy; sustainability
(This special issue belongs to the Section Cardiology)
Clinical Application of Physical Therapy in Neurorehabilitation: 3rd Edition submission deadline 31 Jul 2026 | 2 articles | Viewed by 3705 | Submission Open
Keywords: physical therapy; technology-aided rehabilitation; exercise; neurorehabilitation; neuroplasticity; engagement; self-management
(This special issue belongs to the Section Clinical Rehabilitation)
The Future Direction of Medical Imaging in Hepato-Bilio-Pancreatic Oncology: Challenges and Opportunities
edited by
submission deadline 31 Jul 2026 | 1 articles | Viewed by 1694 | Submission Open
Keywords: MRI; CT; molecular imaging; radiomics; imaging; radiogenomics; precision medicine; outcome prediction; cholangiocarcinoma; pancreatic cancer; imaging biomarkers; treatment response
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Neuro-Psychiatric Disorders: Updates on Diagnosis and Treatment—2nd Edition
edited by
submission deadline 31 Jul 2026 | 2 articles | Viewed by 1324 | Submission Open
Keywords: neuropsychiatric disorder; diagnosis; treatment; neurobiology; organic psychiatry
(This special issue belongs to the Section Mental Health)
Pulmonary Hypertension: From Pathophysiology to Clinical Management
edited by and
submission deadline 31 Jul 2026 | 1 articles | Viewed by 768 | Submission Open
Keywords: pulmonary hypertension; pulmonary arterial hypertension; chronic thromboembolic pulmonary hypertension; pulmonary endarterectomy; balloon pulmonary angioplasty; pharmacological treatment; pathophysiology
(This special issue belongs to the Section Respiratory Medicine)
Interventional Cardiology: Evolving Evidence and Emerging Horizons
edited by
submission deadline 31 Jul 2026 | Viewed by 306 | Submission Open
Keywords: coronary artery disease; percutaneous coronary intervention; drug-coated balloon; intravascular imaging; fractional flow reserve; transcatheter aortic valve implantation; transcatheter mitral valve repair; clinical outcomes
(This special issue belongs to the Section Cardiology)
Advances in Artificial Intelligence Applications for Invasive and Non-Invasive Cardiovascular Procedures
edited by and Rahul Chaudhary
submission deadline 31 Jul 2026 | Viewed by 255 | Submission Open
Keywords: artificial intelligence and machine learning; interventional cardiology; electrophysiology; cardiovascular imaging; remote patient monitoring; digital biomarkers; clinical decision support
(This special issue belongs to the Section Cardiovascular Medicine)
Breakthroughs in the Treatment of Colorectal Cancer
edited by Laura Fortuna and
submission deadline 31 Jul 2026 | Viewed by 212 | Submission Open
Keywords: colorectal cancer; targeted therapy; minimally invasive surgery; immune–oncology integration; enhanced recovery protocols; multidisciplinary care
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
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