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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Research on Pulmonary Hypertension and Its Complications

edited by Gabor G. Kovacs and

Anna Birnhuber

submission deadline 20 Apr 2026 | Viewed by 55 | Submission Open

Keywords: pulmonary hypertension; PH; pulmonary arterial pressure; different diagnostic; therapeutic challenges

(This special issue belongs to the Section Respiratory Medicine)

Innovations in Surgical and Medical Approaches of Urologic Oncology

edited by

Sung Han Kim

submission deadline 20 Apr 2026 | Viewed by 50 | Submission Open

Keywords: urologic oncology; robotic surgery; immunotherapy; targeted therapy; image-guided techniques; personalized medicine; minimally invasive surgery; focal therapy

(This special issue belongs to the Section Nephrology & Urology)

Clinical Cardiac Rehabilitation: Integrating Multidimensional Approaches for Enhanced Cardiovascular Health

edited by

Gaia Cattadori

submission deadline 20 Apr 2026 | Viewed by 50 | Submission Open

Keywords: cardiac rehabilitation; multidimensional approach; integrating approach; cardiovascular health; primary and secondary prevention

(This special issue belongs to the Section Clinical Rehabilitation)

Spinal Cord Injury in Elderly People: Prevention of Complications

edited by Vaidyanathan Subramanian

submission deadline 20 Apr 2026 | Viewed by 46 | Submission Open

Keywords: spinal cord injury; demography; morbidities; complications; spinal injuries; patients; family members; caregivers; general practitioners; discharge; elderly

(This special issue belongs to the Section Geriatric Medicine)

New Challenges and Perspectives in Surgical Treatment of Spinal Deformity

edited by Jung-Hee Lee

submission deadline 20 Apr 2026 | Viewed by 46 | Submission Open

Keywords: adult spinal deformity; decompensation; kyphosis; lateral lumbar interbody fusion; orthopedic surgery; osteotomy; proximal junctional kyphosis; rod fracture

(This special issue belongs to the Section Orthopedics)

Aiming for Early Detection and Prevention of Pulmonary Diseases

edited by

Nektarios Anagnostopoulos

and

Kostas A. Papavassiliou

submission deadline 20 Apr 2026 | Viewed by 38 | Submission Open

Keywords: early diagnosis; prevention strategies; respiratory diseases; artificial intelligence; asthma; chronic obstructive pulmonary disease (COPD); interstitial lung disease; sleep-disordered breathing

(This special issue belongs to the Section Respiratory Medicine)

What Part Do Circulating Tumor Cells Play in Cancers？

edited by

Monika Pizon

and

Katharina Pachmann

submission deadline 20 Apr 2026 | Viewed by 21 | Submission Open

Keywords: circulating tumor cells (CTCs); circulating cancer stem cells (cCSCs); liquid biopsy; therapy monitoring; metastasis; cancer progression

(This special issue belongs to the Section Oncology)

Genitourinary Tumors and Radiation Therapy: Current Advances and Future Directions

edited by Shalini Moningi

submission deadline 20 Apr 2026 | Viewed by 11 | Submission Open

Keywords: cancer; prostate cancer; bladder cancer; kidney cancer; radiation therapy

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Clinical Management of Knee Arthroplasty

edited by

Sang-Hoon Park

submission deadline 21 Apr 2026 | 1 articles | Viewed by 616 | Submission Open

Keywords: knee surgery; knee arthroplasty; knee joint replacement; osteoarthritis; knee arthritis

(This special issue belongs to the Section Orthopedics)

Controversies in Hidradenitis Suppurativa: Bridging Gaps in Science and Practice

edited by Hadar Lev-Tov and Tammy González

submission deadline 21 Apr 2026 | Viewed by 85 | Submission Open

Keywords: hidradenitis suppurativa (HS); inflammatory skin disorder; controversies; treatment strategies; science and practice

(This special issue belongs to the Section Dermatology)

Paediatric Anaesthesia: Clinical Updates and Perspectives

edited by Peter Marhofer, Philipp Opfermann and Markus Zadrazil

submission deadline 24 Apr 2026 | 7 articles | Viewed by 7902 | Submission Open

Keywords: pediatric anesthesia; anesthesia; conduction; ultrasonography; conscious sedation; deep sedation; drug-related side effects and adverse reactions; neurotoxicity syndromes

(This special issue belongs to the Section Anesthesiology)

Challenges and Advances in Geriatrics and Gerontology

edited by Elisa Fabbri

submission deadline 24 Apr 2026 | 2 articles | Viewed by 1361 | Submission Open

Keywords: aging; geriatric medicine; frailty; multimorbidity; sarcopenia; cognition; personalized-care; healthy longevity; decision making-management; prevention; artificial intelligence

(This special issue belongs to the Section Geriatric Medicine)

Advances in Spine Surgery: Current Innovations and Future Directions

edited by

Gonzalo Mariscal

and Jesús Burgos

submission deadline 24 Apr 2026 | Viewed by 114 | Submission Open

Keywords: spine; clinical studies; robotics; minimally invasive; complications; patient-reported outcomes; reviews

(This special issue belongs to the Section Orthopedics)

Innovations and Challenges in Clinical Toxicology and Therapeutic Drug Monitoring

edited by Zhicheng Jin

submission deadline 25 Apr 2026 | 2 articles | Viewed by 18289 | Submission Open

Keywords: toxicology screen; therapeutic drug monitoring; mass spectrometry; immunoassays; pain management; opioids

(This special issue belongs to the Section Pharmacology)

General Anesthesia: Recent Developments and Emerging Trends

edited by Basavana Goudra

submission deadline 25 Apr 2026 | 3 articles | Viewed by 14434 | Submission Open

Keywords: general anesthesia; recent advances; drug development; memory and awareness; brain monitoring; sugammadex; tegileridine

(This special issue belongs to the Section Anesthesiology)

Clinical Management of Oral Healthcare in Diverse Patient Populations: Second Edition

edited by

Antonella Polimeni

and

Iole Vozza

submission deadline 25 Apr 2026 | 7 articles | Viewed by 12342 | Submission Open

Keywords: special needs patients; oral healthcare; pediatric dentistry; dental hygiene; oral pathology; orthodontics; periodontics

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Perspectives on Surgical Management of Knee Injuries

edited by Min Jung

submission deadline 25 Apr 2026 | 5 articles | Viewed by 9658 | Submission Open

Keywords: osteoarthritis; meniscal repair; ligament reconstruction; cartilage restoration; knee surgery

(This special issue belongs to the Section Orthopedics)

Clinical Insights into Pulmonary Hypertension

edited by Simon Schneider

submission deadline 25 Apr 2026 | 5 articles | Viewed by 9478 | Submission Open

Keywords: pulmonary hypertension; pulmonary vascular disease (PVD); pulmonary arterial hypertension (PAH); chronic thromboembolic pulmonary hypertension (CTEPH); interstitial lung disease; chronic obstructive pulmonary disease (COPD); chronic pulmonary fibrosis; emphysema; respiratory disease; physiology; diagnosis; treatment; rehabilitation; altitude research

(This special issue belongs to the Section Respiratory Medicine)

Clinical Advances in Abdominal Surgery

edited by

Juan José Segura-Sampedro

and César P. Ramírez-Plaza

submission deadline 25 Apr 2026 | 5 articles | Viewed by 5977 | Submission Open

Keywords: abdominal surgery; oncologic surgery; minimal invasive techniques; HIPEC; PIPAC; peritoneal carcinomatosis; liver metastasis

(This special issue belongs to the Section General Surgery)

Assessment and Treatment of Trauma Patients

edited by

Arne Driessen

submission deadline 25 Apr 2026 | 2 articles | Viewed by 5897 | Submission Open

Keywords: trauma surgery; prehospital detection of trauma; assessment of trauma; trauma scale; trauma evaluation; trauma surgery

(This special issue belongs to the Section Emergency Medicine)

Advances in Structural Heart Diseases

edited by

Konstantinos Papadopoulos

Ignatios Ikonomidis

and Erwan Donal

submission deadline 25 Apr 2026 | 2 articles | Viewed by 4717 | Submission Open

Keywords: valvular heart diseases; transcatheter interventions; TEER; LAA closure; ASD closure; interventional echocardiography; multimodality cardiac imaging; three-dimensional echocardiography

(This special issue belongs to the Section Cardiovascular Medicine)

Hand Surgery: Latest Advances and Prospects

edited by

Camillo Fulchignoni

and Lorenzo Rocchi

submission deadline 25 Apr 2026 | 3 articles | Viewed by 4195 | Submission Open

Keywords: hand surgery; musculoskeletal and nerve disorders; innovative surgical procedures; minimally invasive techniques; rehabilitation strategies; robotic surgery

(This special issue belongs to the Section Orthopedics)

Advances in the Diagnosis and Treatment of Skin Cancer

edited by

Konstantinos Lallas

and

Aimilios Lallas

submission deadline 25 Apr 2026 | 2 articles | Viewed by 2305 | Submission Open

Keywords: skin cancer; melanoma; keratinocyte carcinoma; basal cell carcinoma; squamous cell carcinoma; biomarkers; immuno-therapy; prognosis

(This special issue belongs to the Section Oncology)

Current Trends and Future Prospects in Autoantibodies in Liver Diseases

edited by Takashi Himoto

submission deadline 25 Apr 2026 | 1 articles | Viewed by 1810 | Submission Open

Keywords: liver-specific autoantibodies; non-organ-specific autoantibodies; autoimmune liver disease; diagnosis; disease activity; treatment outcome; prognosis; virus-induced autoimmunity; drug-induced autoimmunity

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Endometriosis and Endometrial Cancer: Challenge and Clinical Management

edited by

Bogdan Obrzut

, Tomasz Kluz and Bernhard Krämer

submission deadline 25 Apr 2026 | 1 articles | Viewed by 1798 | Submission Open

Keywords: endometriosis; endometrial cancer; non-invasive diagnosis; molecular profiling; surgical techniques; medical treatment; alternative therapies

(This special issue belongs to the Section Obstetrics & Gynecology)

Catheter Ablation of Atrial Fibrillation: Current Progress and New Challenges

edited by Sorin Stefan Popescu, Roland Richard Tilz and Karl-Heinz Kuck

submission deadline 25 Apr 2026 | 1 articles | Viewed by 1744 | Submission Open

Keywords: atrial fibrillation; novel technologies; pulmonary vein isolation; same-day discharge; pulsed field ablation; cryo-ablation; radiofrequency; safety; efficacy; sustainability

(This special issue belongs to the Section Cardiology)

Endoscopic Diagnosis and Treatments of Gastrointestinal Diseases

edited by Madalina Ilie and Mihai Ciocîrlan

submission deadline 25 Apr 2026 | 2 articles | Viewed by 1651 | Submission Open

Keywords: esogastric lesions; pancreatic diseases; colorectal lesions; hepatobiliary diseases; optical endoscopy; endoscopic ultrasound; upper and lower endoscopy; endoscopic retrograde cholangiopancreatography

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Interventional Cardiology: Recent Advances and Future Perspectives

edited by Cristina Aurigemma and Luigi Cappannoli

submission deadline 25 Apr 2026 | 3 articles | Viewed by 1497 | Submission Open

Keywords: interventional cardiology; percutaneous coronary intervention (PCI); transcatheter aortic valve implantation (TAVI); structural heart disease; coronary artery disease; imaging and artificial intelligence; antithrombotic therapy; future technologies in cardiology; personalized cardiovascular care; minimally invasive interventions

(This special issue belongs to the Section Cardiology)

Cardiac Magnetic Resonance Imaging: Current Techniques and Future Directions

edited by Ioannis Botis and

Theodoros D. Karamitsos

submission deadline 25 Apr 2026 | 1 articles | Viewed by 1440 | Submission Open

Keywords: cardiac magnetic resonance imaging; cardiovascular magnetic resonance; cardiac imaging; multimodality imaging; parametric mapping; late gadolinium enhancement; myocardial perfusion; myocardial viability; cardiomyopathies; heart failure

(This special issue belongs to the Section Cardiology)

New Advances in Procedures for the Diagnosis and Treatment of Cardiovascular Disease

edited by

Alexandru Burlacu

and

Adrian Covic

submission deadline 25 Apr 2026 | Viewed by 1361 | Submission Open

Keywords: cardiovascular disease; diagnostic procedures; therapeutic advancements; minimally invasive interventions; precision medicine; imaging technologies; catheter-based treatments; translational research; interventional cardiology; clinical innovations

(This special issue belongs to the Section Cardiovascular Medicine)

General Surgical Oncology: Evolving Paradigms and Contemporary Challenges

edited by

Federica Ferracci

and

Antonio Sommariva

submission deadline 25 Apr 2026 | 1 articles | Viewed by 800 | Submission Open

Keywords: surgical oncology; minimally invasive surgery; robotic surgery; multidisciplinary cancer care; artificial intelligence in surgery; perioperative management; precision oncology; complex tumor resection; integrated surgical therapies; oncologic surgery innovation

(This special issue belongs to the Section Oncology)

Urologic Neoplasms: Recent Advances and Future Perspectives

edited by

Dorit E. Zilberman

submission deadline 25 Apr 2026 | 1 articles | Viewed by 733 | Submission Open

Keywords: robotic surgery; laparoscopic surgery; immunotherapy; chemotherapy; radiotherapy; prostate cancer; renal cancer; bladder cancer; upper urinary tract neoplasm; testicular cancer; penile cancer

(This special issue belongs to the Section Oncology)

Advances in Primary Sclerosing Cholangitis: Pathogenesis, Diagnosis and Emerging Therapies

edited by Konstantinos H. Katsanos and

Fotios S. Fousekis

submission deadline 25 Apr 2026 | 1 articles | Viewed by 571 | Submission Open

Keywords: cholangiocarcinoma; primary sclerosing cholangitis; cholestatic; inflammatory bowel disease; liver

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Robot-Assisted Surgery: Current Trends and Future Directions

edited by

Michele Di Dio

, Claudio Bisegna and Michele Morelli

submission deadline 25 Apr 2026 | Viewed by 402 | Submission Open

Keywords: robotic surgery; minimally invasive surgery; urology; artificial intelligence; augmented reality; public health; innovation; laparoscopic surgery; surgical platforms; surgical outcomes

(This special issue belongs to the Section General Surgery)

Recent Advances in Pulmonary Embolism and Thrombosis: 2nd Edition

edited by

Andrea Boccatonda

and Elena Campello

submission deadline 25 Apr 2026 | 1 articles | Viewed by 376 | Submission Open

Keywords: pulmonary embolism; embolism and thrombosis; thrombus aspiration for pulmonary embolism; deep vein thrombosis; venous thromboembolism

(This special issue belongs to the Section Respiratory Medicine)

New Advances in Cleft Lip and Palate and Facial Plastic Surgery

edited by

Michael Schwaiger

, Wolfgang Zemann and Rainer Lutz

submission deadline 25 Apr 2026 | 1 articles | Viewed by 334 | Submission Open

Keywords: cleft lip repair; rhinoplasty; secondary rhinoplasty; cleft rhinoplasty; facial plastic surgery; nasolabial area; upper lid surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Novel Diagnostic and Therapeutic Approaches to Urologic Oncology

edited by

Cosmin-Victor Ene

, Bogdan Florin Geavlete and

Cristian I. Surcel

submission deadline 25 Apr 2026 | Viewed by 210 | Submission Open

Keywords: diagnosis; therapy; up-to-date; uro-oncologic pathology

(This special issue belongs to the Section Oncology)

New Concepts in Minimally Invasive Spine Surgery

edited by

Yi Lu

and Michael Y. Wang

submission deadline 25 Apr 2026 | Viewed by 183 | Submission Open

Keywords: minimally invasive spine surgery; image navigation; tubular retractor; endoscopic spine surgery; virtual and aug-mented reality; lateral spine surgery

(This special issue belongs to the Section Clinical Neurology)

Liver Failure: Current Status and Future Opportunities

edited by

Stephen Riordan

submission deadline 25 Apr 2026 | Viewed by 96 | Submission Open

Keywords: acute liver failure; acute-on-chronic liver failure; portal hypertension; hepatic encephalopathy; pathogenesis; management

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Sarcoma—Clinical Updates: 2nd Edition

edited by

Julia Visgauss

submission deadline 25 Apr 2026 | Viewed by 83 | Submission Open

Keywords: sarcoma; osteosarcoma; ewing’ s sarcoma; chondrosarcoma; soft-tissue sarcoma; undifferentiated pleo-morphic sarcoma; liposarcoma; leiomyosarcoma; rhabdomyosarcoma; metastatic sarcoma; targeted molecular therapy; immunotherapy; orthopedic oncology

(This special issue belongs to the Section Oncology)

Diagnosis, Treatment and Prognosis of Coronary Heart Disease: 2nd Edition

edited by

Simona Giubilato

submission deadline 25 Apr 2026 | Viewed by 82 | Submission Open

Keywords: coronary heart disease; acute coronary syndrome; chronic coronary syndrome; ischemia with no obstructive coronary arteries (INOCA); guideline-directed optimal medical therapy; precision medicine; artificial intelligence; interventional cardiology; percutaneous coronary intervention (PCI)

(This special issue belongs to the Section Cardiology)

Advances in Reconstructive and Aesthetic Plastic Surgery

edited by

Rafael Loucas

submission deadline 25 Apr 2026 | Viewed by 77 | Submission Open

Keywords: reconstructive plastic surgery; aesthetic innovation; fat grafting; microsurgery; regenerative medicine; cell-enriched lipotransfer; 3D imaging; minimally invasive techniques; hybrid injectables

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

New Clinical Advances in Orthopedic Oncology

edited by

Julia Visgauss

submission deadline 25 Apr 2026 | Viewed by 77 | Submission Open

Keywords: orthopedic oncology; sarcoma; soft-tissue sarcoma; osteosarcoma; chondrosarcoma; Ewings sarcoma; giant cell tumor; limb salvage; mega-prosthetic reconstruction; targeted molecular therapy; immunotherapy

(This special issue belongs to the Section Orthopedics)

Emerging Surgical Techniques in the Management of Urological Diseases

edited by

Riccardo Lombardo

submission deadline 25 Apr 2026 | Viewed by 73 | Submission Open

Keywords: minimally invasive; robotics; partial nephrectomy; radical prostatectomy; focal therapy; benign prostatic hyperplasia; prostate cancer; bladder cancer

(This special issue belongs to the Section Nephrology & Urology)

Complex Scenarios in Reverse Shoulder Arthroplasty: Bone Loss, Revisions, and Surgical Solutions

edited by Francesco Franceschi, Angelo Baldari and Antonio Caldaria

submission deadline 25 Apr 2026 | Viewed by 61 | Submission Open

Keywords: shoulder arthroplasty; revision shoulder arthroplasty; humeral fracture; failed shoulder prosthesis; bone loss management; implant failure

(This special issue belongs to the Section Orthopedics)

Personalized Therapy and Clinical Outcome for Retinal Diseases

edited by

Takeshi Iwase

submission deadline 25 Apr 2026 | Viewed by 58 | Submission Open

Keywords: retinal diseases; retinal imaging; clinical outcomes; artificial intelligence; biomarkers; optical coherence tomography (OCT); vitrectomy

(This special issue belongs to the Section Ophthalmology)

Sex- and Age-Related Differences in Exercise Response: Clinical Implications for Health and Disease

edited by

Rafael A. Casuso

submission deadline 26 Apr 2026 | 2 articles | Viewed by 994 | Submission Open

Keywords: exercise intervention; clinical exercise physiology; sex differences; age-related response; metabolic disorders; personalized medicine; physical activity; chronic disease management

(This special issue belongs to the Section Sports Medicine)

Recent Advances in the Diagnosis and Treatment of Gastrointestinal Diseases

edited by

Ahamed Khalyfa

submission deadline 27 Apr 2026 | 5 articles | Viewed by 4739 | Submission Open

Keywords: advanced endoscopy; innovation in GI; pathophysiology of GI disorders; artificial intelligence in GI; gastrointestinal diseases

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advancing Minimally Invasive Spine Surgery: A Special Edition on Endoscopic Spine Surgery

edited by

Adham M. Khalafallah

and Gregory W. Basil

submission deadline 28 Apr 2026 | 4 articles | Viewed by 6095 | Submission Open

Keywords: minimally invasive spine surgery (MIS); endoscopic spine surgery (ESS); spine surgery; percutaneous spine surgery; full-endoscopic spine surgery; biportal endoscopic spine surgery (BESS); unilateral biportal endoscopy (UBE); percutaneous endoscopic lumbar discectomy (PELD); endoscopic decompression; transforaminal endoscopic lumbar discectomy (TELD); interlaminar endoscopic lumbar discectomy (IELD); endoscopic lumbar fusion; endoscopic transforaminal lumbar interbody fusion (Endo-TLIF)

(This special issue belongs to the Section Clinical Neurology)

Recent Advances and Clinical Outcomes of Hip and Knee Arthroplasty

edited by

Andrea Volpin

submission deadline 28 Apr 2026 | 2 articles | Viewed by 1981 | Submission Open

Keywords: hip arthroplasty; knee arthroplasty; joint replacement; clinical outcomes; surgical innovation; patient recovery; prosthetics; perioperative care

(This special issue belongs to the Section Orthopedics)

Displaying special issue 1201-1250 on page 25 of 31.

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