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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Clinical Advances in Pediatric Asthma

edited by

Davor Plavec

submission deadline 15 Dec 2025 | Viewed by 44 | Submission Open

Keywords: pediatric asthma; clinical management; treatment advances; diagnostic advances; biologic therapy; inhaled steroids; control of asthma; exacerbation prevention; quality of life

(This special issue belongs to the Section Clinical Pediatrics)

Clinical Advances in Cardio-Rheumatology

edited by

Sophie I. Mavrogeni

submission deadline 15 Dec 2025 | Viewed by 40 | Submission Open

Keywords: cardio-rheumatology; autoimmune diseases; cardiac imaging; cardiovascular disease; autoimmune rheumatic diseases

(This special issue belongs to the Section Cardiology)

Key Advances in the Treatment of the Critically Ill: 3rd Edition

edited by

Spyros D. Mentzelopoulos

submission deadline 15 Dec 2025 | Viewed by 36 | Submission Open

Keywords: respiration; artificial; prone position; respiratory distress syndrome; respiratory insufficiency; heart arrest; hypothermia; induced; amiodarone; vasopressins; steroids; epinephrine; multiple trauma; wounds and injuries; tranexamic acid; sepsis; anti-bacterial agents; COVID-19; COVID-19 vaccines; COVID-19 breakthrough infections; COVID-19 drug treatment; extracorporeal membrane oxygenation

(This special issue belongs to the Section Intensive Care)

Clinical Advancements in Intraocular Lens Power Calculation Methods

edited by

Christoph Martin Lwowski

and Thomas Kohnen

submission deadline 15 Dec 2025 | Viewed by 36 | Submission Open

Keywords: emmetropia; IOL power calculation; effective lens position; refractive lens exchange; IOL; refractive surgery; biometry

(This special issue belongs to the Section Ophthalmology)

Clinical Updates on Valvular Heart Diseases: A New Era in Personalized Treatment

edited by Massimiliano Mariani

submission deadline 15 Dec 2025 | Viewed by 34 | Submission Open

Keywords: valvular heart disease; structural heart intervention; imaging in valve disease; interventional echocardiography; minimally invasive cardiac surgery; aortic valve intervention; tricuspid valve intervention; valve intervention in GUCH; patient-specific therapy; advanced diagnostic techniques; gutting-edge cardiac imaging; catheter-based interventions; innovative cardiac therapies

(This special issue belongs to the Section Cardiology)

Novel Prognostic Risk Factors in Acute Coronary Syndrome

edited by

Nicola Cosentino

and

Andrea Baggiano

submission deadline 15 Dec 2025 | Viewed by 26 | Submission Open

Keywords: acute coronary syndrome; risk stratification; biomarkers; cardiovascular imaging; inflammation; genetics; heart– kidney interaction; cardio-pulmonary complications; neurological dysfunction; precision medicine

(This special issue belongs to the Section Cardiology)

Thoracic Surgery: Current Practice and Future Directions: 2nd Edition

edited by

Dania Nachira

submission deadline 15 Dec 2025 | Viewed by 25 | Submission Open

Keywords: NSCLC; mediastinum; thymoma; esophageal disease; immunotherapy; new technologies; minimally invasive surgery; VATS; RATS

(This special issue belongs to the Section Respiratory Medicine)

Gender Differences and Diversity in the Treatment of Gastric Cancer and Other Malignancies

edited by Claus Schildberg and Frank Meyer

submission deadline 15 Dec 2025 | Viewed by 23 | Submission Open

Keywords: gastric cancer; other cancers; other treatment; gender differences; diversity; new challances

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Emergency Surgery: Clinical Updates and New Perspectives

edited by

Bruno Cirillo

submission deadline 15 Dec 2025 | Viewed by 23 | Submission Open

Keywords: emergency surgery; trauma surgery; acute abdomen; hernia emergencies; surgical decision making; perioperative care; damage control surgery; emergency management; critical care surgery; multidisciplinary approach

(This special issue belongs to the Section Emergency Medicine)

New Frontiers in Therapeutic Drug Monitoring of Biologics in Inflammatory Bowel Disease and Other Immune-Mediated Inflammatory Diseases: 2nd Edition

edited by

Konstantinos Papamichael

submission deadline 15 Dec 2025 | Viewed by 19 | Submission Open

Keywords: therapeutic drug monitoring; inflammatory bowel diseases; immune mediated inflammatory diseases; pharmacokinetics; anti-TNF; vedolizumab; ustekinumab; risankizumab; point-of-care assays; model informed precision dosing

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in Diagnostic and Surgical Treatment in Lung Cancer and Related Pulmonary Disorders

edited by Natalia Motas and Veronica Manolache

submission deadline 17 Dec 2025 | Viewed by 33 | Submission Open

Keywords: lung cancer; minimally invasive thoracic surgery (MITS); video-assisted thoracoscopic surgery (VATS); robot-assisted thoracic surgery (RATS); interventional pneumology; bronchoscopy; endobronchial ultrasound (EBUS); artificial intelligence (AI); lung nodule

(This special issue belongs to the Section Respiratory Medicine)

Recent Advances in Transcatheter Aortic Valve Replacement: Second Edition

edited by

Anna Olasińska-Wiśniewska

and Maciej Dąbrowski

submission deadline 18 Dec 2025 | Viewed by 43 | Submission Open

Keywords: aortic stenosis; transcatheter; bioprosthesis; TAVI; transcatheter aortic valve replacement

(This special issue belongs to the Section Cardiovascular Medicine)

Innovations in the Clinical Management of Retinal Diseases: Emerging Therapies and Visual Rehabilitation

edited by

Francisco J. Povedano-Montero

submission deadline 19 Dec 2025 | 1 articles | Viewed by 279 | Submission Open

Keywords: retinal diseases; macular degeneration; maculopathies; diabetic retinopathy; retinal vascular occlusions; retinitis pigmentosa

(This special issue belongs to the Section Ophthalmology)

Updates on the Clinical Applications of Dental Restorative Materials

edited by

Vittorio Checchi

submission deadline 20 Dec 2025 | 1 articles | Viewed by 363 | Submission Open

Keywords: restorative dentistry; restorations; adhesive dentistry; resin composites; ceramics; aesthetics; dental materials; direct restorations; indirect restorations; conservative dentistry; prosthetic dentistry; partial restorations; total restorations

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advancements in Gait Rehabilitation: Innovative Approaches and Clinical Insights

edited by

Shinichi Watanabe

Nobuto Nakanishi

and

Yuki Iida

submission deadline 20 Dec 2025 | Viewed by 148 | Submission Open

Keywords: sarcopenia; swallowing therapy; physical therapy; early mobilization; early rehabilitation; robot-assisted gait training; neurorehabilitation; wearable sensors

(This special issue belongs to the Section Clinical Rehabilitation)

Gynecologic and Obstetric Pathologies: From Birth to Menopause (Third Edition)

edited by

Panagiotis Christopoulos

submission deadline 20 Dec 2025 | Viewed by 120 | Submission Open

Keywords: obstetrics; gynecology; pathology; pediatric and adolescent gynecology; menopause; urinary disorders; infertility; gynecologic oncology; maternal– fetal medicine; incontinence; menstruation; reproduction; polycystic ovarian syndrome; endometriosis; dysmenorrhea; assisted reproduction; IVF; laparoscopy; hysteroscopy; gynecologic robotic surgery; high-risk pregnancy

(This special issue belongs to the Section Obstetrics & Gynecology)

Anesthesia and Intensive Care in Orthopedic and Trauma Surgery

edited by Liliana Mirea, Răzvan Ene and Cristian Cobilinschi

submission deadline 20 Dec 2025 | Viewed by 105 | Submission Open

Keywords: opioid sparing analgetic technique; pain management; perioperative medicine; perioperative cognitive disfunction; delirium

(This special issue belongs to the Section Intensive Care)

New Clinical Advances in Breast Reconstruction

edited by

Nobuyuki Mitsukawa

submission deadline 20 Dec 2025 | Viewed by 69 | Submission Open

Keywords: breast reconstruction; autologous (flap) reconstruction; implant-based reconstruction; microsurgery and perforator flaps; robotic surgery/endoscopic surgery; fat grafting (lipofilling); patient-reported outcomes; reconstructive surgical innovation

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Key Challenges in Heart Transplantation and Their Solutions

edited by Elizabeth J. Maynes

submission deadline 20 Dec 2025 | Viewed by 55 | Submission Open

Keywords: heart transplantation; heart failure; cardiac surgery; minimally invasive techniques; general surgery; heart diseases

(This special issue belongs to the Section Cardiology)

Clinical Innovations in Dental Implant: Expanding Possibilities for Oral Rehabilitation

edited by Marco Severino

submission deadline 20 Dec 2025 | Viewed by 49 | Submission Open

Keywords: dental implants; oral rehabilitation; computer-guided surgery; biocompatibility; regenerative treatments; mini-implants; minimally invasive surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Status, Application and Future Directions of Artificial Urinary Sphincters

edited by JiSung Shim

submission deadline 20 Dec 2025 | Viewed by 44 | Submission Open

Keywords: ISD; robot surgery; neurogenic SUI; female AUS; complication; erosion; urethroplasty; malfunction; PPI; BOO

(This special issue belongs to the Section Nephrology & Urology)

Current and Emerging Treatment Options in Intestinal and Stomach Neoplasms

edited by

Ioannis Konstantinidis

submission deadline 20 Dec 2025 | Viewed by 44 | Submission Open

Keywords: colorectal cancer; colon cancer; gastric carcinoma; malignancy; gastroenterology; endoscopic techniques; therapeutic advancements; intestinal neoplasms

(This special issue belongs to the Section Oncology)

Clinical Research and Insights in Endometriosis

edited by

Nikolaos Machairiotis

submission deadline 20 Dec 2025 | Viewed by 35 | Submission Open

Keywords: endometriosis; pelvic pain; infertility; inflammation; minimal access surgery; laparoscopy; hysteroscopy; robotics

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in Lung Transplantation and Interventional Pulmonology

edited by Anupam Kumar and Frye Laura

submission deadline 20 Dec 2025 | Viewed by 34 | Submission Open

Keywords: lung transplantation; interventional pulmonology; immunosuppressive therapies; organ rejection; pulmonary rehabilitation; surgical innovations; post-transplant complications; diagnostic advancements; donor lung shortage; thoracic surgery

(This special issue belongs to the Section Respiratory Medicine)

Surgical Oncology: Clinical Application of Translational Medicine

edited by Domenico Parmeggiani

submission deadline 20 Dec 2025 | Viewed by 34 | Submission Open

Keywords: surgical oncology; drug safety; adverse events; nanovesicles; targeted drug delivery; cancer biomarkers; precision oncology; tumor microenvironment; nanomedicine; personalized medicine; diagnostics; prognosis; innovative therapies; translational research

(This special issue belongs to the Section Oncology)

Cardiovascular Imaging: Diagnosis and Therapeutic Guidance in Clinical Practice

edited by

Stefano Figliozzi

submission deadline 20 Dec 2025 | Viewed by 34 | Submission Open

Keywords: cardiovascular magnetic resonance; cardiac imaging; T1 and T2 mapping; myocardial tissue characterization; late gadolinium enhancement; ischemic heart disease; cardiomyopathies; valvular heart disease; therapeutic guidance; precision medicine; mitral valve prolapse

(This special issue belongs to the Section Cardiology)

Risk Factors in Neonatal Intensive Care

edited by

Gabriela C. Zaharie

and

Melinda Matyas

submission deadline 20 Dec 2025 | Viewed by 34 | Submission Open

Keywords: neonatal intensive care; infant birth; preterm; neonatal resuscitation; neonatal outcome; growth restriction; prenatal diagnosis; severe maternal pathology and its effects on a newborn; therapeutical hypothermia; parenteral nutrition; neonatal infection; retinopathy of prematurity

(This special issue belongs to the Section Clinical Pediatrics)

New Perspectives in Maternal–Fetal Medicine

edited by Catalina de Paco-Matallana

submission deadline 20 Dec 2025 | Viewed by 31 | Submission Open

Keywords: maternal– fetal medicine; prenatal diagnostics; fetal therapy; precision medicine; neonatal outcomes; maternal health

(This special issue belongs to the Section Obstetrics & Gynecology)

The Treatment of BPO with Minimal Invasive Approach

edited by

Lukas Lusuardi

submission deadline 20 Dec 2025 | Viewed by 30 | Submission Open

Keywords: benign prostatic obstruction (BPO); prostatectomy; non-muscle invasive bladder cancer; muscle invasive bladder cancer; robotic surgery

(This special issue belongs to the Section Nephrology & Urology)

Elevating Standards in Anesthesia Monitoring

edited by

Marco Cascella

submission deadline 20 Dec 2025 | Viewed by 30 | Submission Open

Keywords: monitoring; analgesia; pain; nociception; awareness anesthesia; postoperative delirium; closed-loop anes-thesia; artificial intelligence

(This special issue belongs to the Section Anesthesiology)

Advances in Periodontitis and Other Periodontal Diseases

edited by

Giovanna Murmura

submission deadline 20 Dec 2025 | Viewed by 28 | Submission Open

Keywords: periodontal diseases; gingivitis; periodontitis; systemic disease; classification

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Neurological Rehabilitation: Repair Mechanisms, Plasticity, and Connectomes

edited by Thomas Mokrusch and Frank Kirchhoff

submission deadline 20 Dec 2025 | Viewed by 26 | Submission Open

Keywords: neurorehabilitation; therapeutic approaches; repair mechanism; plasticity; neurology

(This special issue belongs to the Section Clinical Neurology)

Recent Developments in Urinary Incontinence

edited by

Michael Samarinas

submission deadline 20 Dec 2025 | Viewed by 25 | Submission Open

Keywords: urinary incontinence; overactive bladder; stress urinary incontinence; pelvic floor dysfunction; urodynamics; minimally invasive treatment; neuromodulation; regenerative medicine; conservative management; digital health in urology

(This special issue belongs to the Section Nephrology & Urology)

Clinical Perspectives of Vascular and Endovascular Surgeries

edited by

Adrian Vasile Muresan

Emil Marian Arbănași

and

Eliza Russu

submission deadline 20 Dec 2025 | Viewed by 23 | Submission Open

Keywords: vascular surgery; varicose veins; abdominal aortic aneurysms; carotid disease; peripheral arterial disease

(This special issue belongs to the Section Vascular Medicine)

Clinical Management of Bladder Cancer

edited by

Antonio Franco

, Antonio Cicione and

Francesco Ditonno

submission deadline 20 Dec 2025 | Viewed by 23 | Submission Open

Keywords: bladder cancer; minimally invasive surgery; immunotherapy; targeted therapy; biomarkers; imaging techniques; muscle invasive bladder cancer; non-muscle-invasive bladder cancer

(This special issue belongs to the Section Nephrology & Urology)

Laparoscopy and Surgery in Gynecologic Oncology: 2nd Edition

edited by Zoltan Novak

submission deadline 20 Dec 2025 | Viewed by 22 | Submission Open

Keywords: gynecologic cancers; ovarian; uterine; cervical; laparoscopy; diagnosis; staging; treatment; palliative care; fertility preservation

(This special issue belongs to the Section Obstetrics & Gynecology)

Hospital-Acquired Infections: Insights, Prevention, and Control Strategies

edited by

Andrea Fabbri

submission deadline 20 Dec 2025 | Viewed by 21 | Submission Open

Keywords: healthcare-acquired infections; bloodstream infections; hospital‐acquired pneumonia; intestinal infections; clostridium difficile; surgical site infections; urinary tract infections; emergency department

(This special issue belongs to the Section Epidemiology & Public Health)

New Insights in Maxillofacial Surgery

edited by

Izumi Asahina

submission deadline 20 Dec 2025 | Viewed by 17 | Submission Open

Keywords: maxillofacial surgery; surgical techniques; imaging technologies; biomaterials; regenerative medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Clinical Management of Temporomandibular Joint Diseases

edited by

João Luiz Monteiro

submission deadline 20 Dec 2025 | Viewed by 13 | Submission Open

Keywords: minimally invasive surgical procedure; artificial intelligence; temporomandibular joint disorders; temporomandibular disorders; temporomandibular joint

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Gastric Cancer: Epidemiology, Clinical Management and Emerging Biomarkers

edited by

Akira Tsuburaya

and

Takashi Oshima

submission deadline 20 Dec 2025 | Viewed by 11 | Submission Open

Keywords: gastric cancer; metabolism; biomarkers; surgical stress; adjuvant therapy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Applications of Artificial Intelligence in Cardiology: New Tools to Transform Care

edited by

Constantinos Bakogiannis

submission deadline 20 Dec 2025 | Viewed by 5 | Submission Open

Keywords: artificial intelligence in cardiology; machine learning; deep learning; AI-driven ECG analysis; cardiovas-cular imaging and AI; predictive analytics in cardiology; mHealth and wearables; clinical decision support systems; ethics and AI in healthcare; digital health and remote monitoring

(This special issue belongs to the Section Cardiology)

Advanced Technologies, Concepts, and Topics in Modern Neurosurgery

edited by

Samer Zawy Alsofy

and Ralf Stroop

submission deadline 20 Dec 2025 | Viewed by 3 | Submission Open

Keywords: modern neurosurgery; virtual reality; augmented reality; intraoperative imaging; neuronavigation; artificial intelligence; machine learning; robotic surgery; 3D printing; neurovascular interventions; neuro-oncology; skull base surgery; functional neurosurgery; spinal neurosurgery; surgical innovation; image-guided surgery; personalized neurosurgical planning

(This special issue belongs to the Section General Surgery)

Scoliosis: Advances in Diagnosis and Management

edited by Michal Latalski

submission deadline 22 Dec 2025 | Viewed by 108 | Submission Open

Keywords: scoliosis; adolescent idiopathic scoliosis; adult scoliosis; congenital scoliosis; neuromuscular scoliosis; diagnosis; imaging; treatment; surgery; bracing; rehabilitation; patient-reported outcomes; quality of life

(This special issue belongs to the Section Orthopedics)

Oral Surgery: Recent Advances and Future Perspectives

edited by

Carlo Barausse

and

Gerardo Pellegrino

submission deadline 22 Dec 2025 | Viewed by 35 | Submission Open

Keywords: oral surgery; implant dentistry; atrophic jaws; bone regeneration; digital dentistry

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Innovative Aspects in Dental Implantology and Related Clinical Research (Second Edition)

edited by

Carlo Barausse

and

Gerardo Pellegrino

submission deadline 22 Dec 2025 | Viewed by 34 | Submission Open

Keywords: dental implants; implantology; bone regeneration; implant-supported prosthesis; zygomatic implants; reconstructive surgery; pre-implant surgery; short implants

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Ablation, Embolization, and Stenting: Current Trends in Interventional Radiology

edited by Praveen Peddu

submission deadline 22 Dec 2025 | Viewed by 32 | Submission Open

Keywords: interventional radiology; ablation; embolization; stenting; minimally invasive therapy

(This special issue belongs to the Section Nuclear Medicine & Radiology)

New Advances in Stereotactic Radiosurgery

edited by Shafak S. Aluwini

submission deadline 24 Dec 2025 | Viewed by 27 | Submission Open

Keywords: stereotactic radiosurgery; clinical outcomes; brachytherapy; IMRT; brain metastases; arteriovenous malformations; functional disorders; radiosurgery

(This special issue belongs to the Section Oncology)

Clinical Advances in Radiation Therapy for Cancers

edited by

Rodica Maricela Anghel

Liviu Bîlteanu

and

Laura Florentina Rebegea

submission deadline 25 Dec 2025 | 2 articles | Viewed by 245 | Submission Open

Keywords: radiation oncology; radiotherapy; cancer radiotherapy; cancer radiation therapy; radiobiology; predictive and prognostic biomarkers; cancer treatment; heavy ions radiation oncology; protontherapy; cancer biolology

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Recent Research Progress in Pediatric Orthopedic Surgery

edited by

Catharina Chiari

and Madeleine Willegger

submission deadline 25 Dec 2025 | Viewed by 98 | Submission Open

Keywords: pediatric orthopedics; deformity correction; pediatric hip; pediatric trauma; basic research in pediatric orthopedics; clubfoot; pediatric foot and ankle deformities; pediatric hand

(This special issue belongs to the Section Clinical Pediatrics)

State-of-the-Art in Cardiac Surgery: Progress, Challenges and Opportunities

edited by Tomasz Plonek and Sleiman Sebastian Aboul-Hassan

submission deadline 25 Dec 2025 | Viewed by 43 | Submission Open

Keywords: aorta ascendens; minimally invasive surgery; aortic arch surgery; off pump coronary surgery; arterial grafts

(This special issue belongs to the Section Cardiology)

Displaying special issue 1201-1250 on page 25 of 27.

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