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Challenges and Advances in Geriatrics and Gerontology
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Challenges and Advances in Geriatrics and Gerontology

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Geriatric Medicine".

Deadline for manuscript submissions: 24 October 2025 | Viewed by 359

Special Issue Editor

Dr. Elisa Fabbri

E-Mail Website
Guest Editor
1. Division of Internal Medicine, Morgagni-Pierantoni Hospital Forlì, Forlì, Italy
2. Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
Interests: multimorbidity; frailty; biology of aging; inflammation; geriatric medicine; cognition; cardiovascular diseases

Special Issue Information

Dear Colleagues,

The aging population is a worldwide phenomenon resulting in an increasing burden of multimorbidity, frailty, and disability with relevant challenges for healthcare systems and society. Older and frail patients with multiple chronic conditions are more complex than their younger counterparts and not adequately represented in clinical trials and guidelines, with consequent difficulties in decision-making and clinical/surgical management. Therefore, an urgent need is to optimally implement tailored treatments and recommendations for older and complex patients. Indeed, a holistic approach and a multidisciplinary team are required to provide personalized models of care, centered on the patient’s needs and priorities. Moreover, strategies for primary, secondary, and tertiary prevention are necessary to promote healthy aging, starting from a life course perspective, even from early life. Whether and how technology advances, such as artificial intelligence, may be useful to achieve these goals is still a matter of discussion. 

The Journal of Clinical Medicine (JCM) is introducing this Special Issue, which aims to discuss challenges and recent advances in geriatric medicine and gerontology. We sincerely welcome contributions (original clinical and experimental research studies, reviews, and meta-analyses) focused on promoting healthy longevity and implementing personalized care for older adults with frailty and multimorbidity. 

Dr. Elisa Fabbri
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • aging
  • geriatric medicine
  • frailty
  • multimorbidity
  • sarcopenia
  • cognition
  • personalized-care
  • healthy longevity
  • decision making-management
  • prevention
  • artificial intelligence

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Published Papers (1 paper)

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Research

15 pages, 924 KiB  
Article
The Role of Periarticular Knee Muscle Torques in Ensuring the Body Balance of Older Adults with Balance Disturbances
by Piotr Prochor, Łukasz Magnuszewski, Paulina Zalewska, Michał Świętek, Zyta Beata Wojszel and Szczepan Piszczatowski
J. Clin. Med. 2025, 14(9), 3251; https://doi.org/10.3390/jcm14093251 - 7 May 2025
Viewed by 253
Abstract
Background: The role of the periarticular muscles of the knee joint in ensuring body balance is still ambiguous. Therefore, we conducted clinical and biomechanical assessments on 52 older adults (36 women and 16 men, age of 67.58 ± 7.30 years, body weight [...] Read more.
Background: The role of the periarticular muscles of the knee joint in ensuring body balance is still ambiguous. Therefore, we conducted clinical and biomechanical assessments on 52 older adults (36 women and 16 men, age of 67.58 ± 7.30 years, body weight of 75.10 ± 13.42 kg, and height of 163.92 ± 8.80 cm) to determine the role of the knee muscles in balance maintenance. Methods: The clinical examination included the Dizziness Handicap Inventory (DHI), the Geriatric Depression Scale (GDS), the Performance-Oriented Mobility Assessment (POMA), the Functional Reach Test (FRT), the Falls Efficacy Scale—International (FES-I), and bioimpedance parameters (skeletal muscle mass—SMM—and its derived parameter—Diff SMM). The biomechanical assessment involved parameters that characterize muscle torques of knee joint extensors and flexors in isokinetic and isometric conditions, as well as changes in the centre of pressure (COP) position while standing with eyes open and closed. Results: Based on treatment history and DHI results (>10 points), 26 participants were identified as having balance disorders, while the remaining participants formed the control group. Statistical analysis was performed to determine differences between the groups. The groups significantly differed in terms of the results obtained from the DHI (p < 0.001) and GDS (p = 0.04) questionnaires as well as FES-I (p < 0.001) and POMA (p = 0.002) tests. While SMM (p = 0.012) was similar in the groups, Diff SMM (p = 0.04) significantly differed. The multiple regression analysis confirmed the knee joint extensor parameters’ significant role in predicting the COP path (p = 0.03 and p = 0.04 for two assumed models). Conclusions: The obtained results proved that the muscle torques of knee extensors can be used in the diagnostic process of older patients with balance disorders, indicating possible rehabilitation directions. Full article
(This article belongs to the Special Issue Challenges and Advances in Geriatrics and Gerontology)
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