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Endoscopic Diagnosis and Treatments of Gastrointestinal Diseases
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Endoscopic Diagnosis and Treatments of Gastrointestinal Diseases

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

Deadline for manuscript submissions: 25 October 2025 | Viewed by 302

Special Issue Editors

Dr. Madalina Ilie

E-Mail Website
Guest Editor
Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania
Interests: interventional endoscopic ultrasound; colorectal cancer; Helicobacter pylori
Dr. Mihai Ciocîrlan

E-Mail Website
Guest Editor
Gastroenterology Clinic, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania
Interests: endoscopic submucosal dissection; endoscopic ultrasound; pancreatic cancer

Special Issue Information

Dear Colleagues,

We are pleased to announce the launch of this Special Issue, entitled “Endoscopic Diagnosis and Treatments of Gastrointestinal Diseases”.

In recent years, the management of gastrointestinal diseases has gradually shifted from a surgical approach to endoscopic diagnosis and treatment. This is due to two main factors. Firstly, advances in optical endoscopic techniques for macroscopic and microscopic imaging have led to the precise diagnosis of premalignant lesions or early cancers. Secondly, the endoscopic field has seen the rapid advent of novel techniques (such as endoscopic mucosal dissection, endoscopic ultrasound-guided drainage, and digestive anastomosis) for the treatment of gastrointestinal diseases.

Our aim for this Special Issue is to provide a broad overview of the state of the art, as well as knowledge from personal experience, of endoscopic diagnosis, techniques, and novel minimally invasive treatments in various gastrointestinal diseases. In this way, we hope to expand the knowledge in this field, enabling endoscopy to cure patients or improve survival and quality of life.

We welcome the submission of original articles and reviews related to challenges encountered in the endoscopic management of digestive diseases.

Dr. Madalina Ilie
Dr. Mihai Ciocîrlan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • esogastric lesions
  • pancreatic diseases
  • colorectal lesions
  • hepatobiliary diseases
  • optical endoscopy
  • endoscopic ultrasound
  • upper and lower endoscopy
  • endoscopic retrograde cholangiopancreatography

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

9 pages, 383 KiB  
Article
Site of Biopsy and Its Accuracy in Preoperative Diagnosis of Superficial Nonampullary Duodenal Epithelial Tumors: Retrospective Study
by Yukihisa Fujinaga, Akira Mitoro, Hitoshi Mori, Satoshi Iwai, Takahiro Kubo, Misako Tanaka, Aritoshi Koizumi, Fumimasa Tomooka, Shohei Asada, Koh Kitagawa, Norihisa Nishimura, Shinya Sato, Kosuke Kaji, Tadashi Namisaki and Hitoshi Yoshiji
J. Clin. Med. 2025, 14(8), 2579; https://doi.org/10.3390/jcm14082579 - 9 Apr 2025
Viewed by 192
Abstract
Background/Objectives: As endoscopy is increasingly being used to diagnose superficial nonampullary duodenal epithelial tumors (SNADETs), there is a growing need for their early detection and minimally invasive treatment. This study investigated the diagnostic accuracy of biopsy specimens for SNADETs. Methods: We conducted a [...] Read more.
Background/Objectives: As endoscopy is increasingly being used to diagnose superficial nonampullary duodenal epithelial tumors (SNADETs), there is a growing need for their early detection and minimally invasive treatment. This study investigated the diagnostic accuracy of biopsy specimens for SNADETs. Methods: We conducted a retrospective analysis of clinicopathologic data from 98 patients with SNADETs who had undergone endoscopic resection. The presurgical diagnosis, based on biopsy specimens, was compared with the histological diagnosis of the excised specimens. Results: Herein, preoperative biopsies were performed on 98 SNADETs specimens from 91 patients. Of the 68 adenomas and 30 carcinomas, 22.4% adenomas were later found to be carcinomas. Carcinoma biopsy diagnosis sensitivity, specificity, and accuracy were 54.6%, 80.0%, and 71.4%, respectively. Biopsy accuracy for carcinoma differed significantly by location to the papilla of Vater (p = 0.0455). The preoperative biopsy diagnostics’ sensitivity, specificity, and accuracy for oral and anal carcinomas to Vater papilla were 69.2%, 92.0%, and 84.2% and 42.1%, 73.2%, and 63.3%, respectively. Conclusions: The diagnostic accuracy of biopsy for SNADETs was low; however, it was higher on the oral side than the anal side of the papilla of Vater. The biopsy of duodenal lesions should be performed after an endoscopic examination, considering their location and reducing the risks of fibrosis. Full article
(This article belongs to the Special Issue Endoscopic Diagnosis and Treatments of Gastrointestinal Diseases)
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