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Clinical Cardiac Rehabilitation: Integrating Multidimensional Approaches for Enhanced Cardiovascular Health

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Rehabilitation".

Deadline for manuscript submissions: 20 December 2026 | Viewed by 1213

Editor


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Guest Editor
IRCCS Multimedica, Cardiovascular Research Unit, 35128 Milan, Italy
Interests: rehabilitation; exercise physiology; exercise performance; exercise testing; physical activity assessment; exercise; physical activity; oxygen consumption; cardiac rehabilitation; cardiopulmonary exercise testing; cardiovascular rehabilitation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Clinical Cardiac Rehabilitation Centers are increasingly recognized as optimal settings for the management of cardiovascular patients. They provide integrated clinical and instrumental assessments, supervised exercise training, and evidence-based strategies for both primary and secondary prevention through a multidisciplinary and multiparametric approach.

This Special Issue aims to collect and disseminate original studies, clinical cases, and reviews that highlight the potential of the rehabilitation setting within the healthcare system, both for promoting health in the context of primary prevention and for implementing timely and effective secondary prevention interventions.

Dr. Gaia Cattadori
Guest Editor

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Keywords

  • cardiac rehabilitation
  • multidimensional approach
  • integrating approach
  • cardiovascular health
  • primary and secondary prevention

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Published Papers (2 papers)

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Research

16 pages, 1451 KB  
Article
Functional Thresholds Derived from Dynamometry and 6-Minute Walk Test with Morphofunctional Assessment to Guide Individualized Exercise Prescription in Cardiac Rehabilitation
by María del Mar Amaya-Campos, Ramón Zafra Jiménez, Rocío Fernández-Jiménez, Isabel M. Vegas-Aguilar, María García-Olivares, Mónica Diaz-Cordovés Rego, Yolanda Ruiz Molina, Adela María Gómez González, Angel Montiel Trujillo, Francisco Tinahones-Madueño, José Manuel García-Almeida and Lucía Jiménez Laguna
J. Clin. Med. 2026, 15(11), 4336; https://doi.org/10.3390/jcm15114336 - 3 Jun 2026
Viewed by 307
Abstract
Background/Objectives: To evaluate the associations and concurrent validity between baseline functional and morphofunctional assessments in patients with cardiovascular disease participating in a Phase II cardiac rehabilitation program, as a basis for informing individualized exercise prescription. Methods: We conducted an observational retrospective [...] Read more.
Background/Objectives: To evaluate the associations and concurrent validity between baseline functional and morphofunctional assessments in patients with cardiovascular disease participating in a Phase II cardiac rehabilitation program, as a basis for informing individualized exercise prescription. Methods: We conducted an observational retrospective cross-sectional study of patients enrolled in a Phase II outpatient cardiac rehabilitation program (January 2021–December 2023, Málaga). Functional assessments included handgrip strength (HGS), isometric biceps and quadriceps dynamometry, and direct assessment of 20-repetition maximum (20RM) through dynamic resistance exercises using external loads (defined as the maximum load allowing approximately 20 repetitions to near muscular fatigue). Aerobic capacity was evaluated using the 6-min walk test (6 MWT) and a modified Bruce exercise stress test with estimated METs. Morphofunctional assessment included vector bioimpedance analysis (phase angle [PhA], fat-free mass [FFM], body cell mass [BCM]) and rectus femoris ultrasound (cross-sectional area [RF-CSA] and contracted diameter [RF-CON]). Correlation and linear regression analyses were performed. Results: The sample included 223 participants (78.0% male; age 57.7 ± 8.6 years). HGSmax correlated strongly with 20RM biceps (r = 0.89) and moderately with quadriceps (r = 0.72). 6 MWT distance and speed correlated with ergometry-derived METs (r = 0.38–0.40; p < 0.001), whereas Borg ratings correlated inversely with METs and exercise time (r = −0.32 to −0.34; p < 0.001). PhA, BCM, FFM, and rectus femoris ultrasound measures correlated with both strength and aerobic outcomes (ρ ≈ 0.33–0.50; all p < 0.001). In regression analyses, HGSmax was the main predictor of 20RM biceps (R2 = 0.792) and showed moderate predictive capacity for quadriceps performance (R2 = 0.521). The MET model demonstrated limited explanatory capacity (R2 = 0.288). Conclusions: The integration of simple, accessible, and reproducible tools such as HGS and the 6 MWT with morphofunctional parameters may provide a pragmatic approach to support individualized exercise prescription in cardiac rehabilitation. While stronger associations were observed for upper-limb resistance performance, the predictive capacity for lower-limb strength and aerobic exercise intensity was more moderate and should be interpreted cautiously. These findings support the potential clinical utility of combining functional and morphofunctional assessments in routine cardiac rehabilitation practice. Full article
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16 pages, 1540 KB  
Article
Pericardial Effusion After Cardiac Surgery: Prevalence, Characteristics, Risk Factors and Management
by Gaia Cattadori, Anna Picozzi, Elena Tagliabue, Giovanna Elsa Ute Muti Schuenemann, Tiziana Staine, Roberta Chiodelli, Anna Scaglione, Barbara Baronio, Silvia Di Marco and Claudio Anzà
J. Clin. Med. 2026, 15(8), 3101; https://doi.org/10.3390/jcm15083101 - 18 Apr 2026
Viewed by 617
Abstract
Background/Objectives: Pericardial effusion (PEf) is a frequent finding after cardiac surgery. Progression to cardiac tamponade (CT) is a rare but life-threatening complication. Current evidence remains limited due to insufficient data on prevalence, progression predictors and management strategies. Methods: We retrospectively analyzed anamnestic, clinical, [...] Read more.
Background/Objectives: Pericardial effusion (PEf) is a frequent finding after cardiac surgery. Progression to cardiac tamponade (CT) is a rare but life-threatening complication. Current evidence remains limited due to insufficient data on prevalence, progression predictors and management strategies. Methods: We retrospectively analyzed anamnestic, clinical, laboratory, echocardiographic and therapeutic data from 2662 patients (74 ± 11 years) admitted to the Cardiac Rehabilitation ward between 2022 and 2024. Results: Among 2152 (81%) cardiac surgery patients, 382 (18%) developed PEf: 58% mild, 38% moderate, and 4% severe. Patients developing PEf tended to be younger and more frequently male. In addition, PEf development was seen more commonly after aortic and combined surgeries. All patients with severe PEf or CT had undergone surgery via sternotomy, whereas minithoracotomy was inversely associated with PEf severity. Postoperative complications occurred in 92% of PEf patients, mainly due to arrhythmia, hemodynamic deterioration, or heart failure. Overall outcome was favourable in 98% of patients. CT occurred in eight patients (2%). Anticoagulation therapy was more frequent among patients who developed PEf or CT. Preventive colchicine was prescribed in only 16% of cases. No PEf-specific therapy was administered in 56% of PEf patients, while corticosteroids and nonsteroidal anti-inflammatory drugs were used in 28% and 8% of cases, respectively, without surgical wound complications. No PEf recurrences were observed during follow up (517 ± 424 days). Conclusions: PEf is a common complication after cardiac surgery, more frequently in young males, usually of mild or moderate severity. The majority of these cases resolve using either a conservative or pharmacological approach, predominantly via corticosteroids. Patients undergoing aortic surgery, experiencing postoperative complications (especially arrhythmias), and receiving anticoagulation therapy were associated with severe PEf or CT. Despite guideline recommendations, colchicine remains markedly underutilized. Full article
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