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Clinical Management of Knee Arthroplasty

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: 25 October 2026 | Viewed by 3364

Special Issue Editor


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Guest Editor
Department of Orthopedic Surgery, National Health Insurance Service Ilsan Hospital, Goyang 10444, Republic of Korea
Interests: knee; arthroplasty; arthroscopy; anterior cruciate ligament (ACL); posterior cruciate ligament (PCL); osteotomy; meniscus; arthritis

Special Issue Information

Dear Colleagues,

We are performing a lot of total knee arthroplasty in the last stage of degenerative arthritis. As the lifespan of humans gradually increases, the number of patients suffering from degenerative knee arthritis is expanding, and eventually, the number of patients undergoing artificial knee arthroplasty surgery is increasing. In performing such artificial knee arthroplasty, as patients become older, managing it becomes very important.

This profound and ongoing change is not just about advancing surgical techniques or artificial joint substitutions, but also about integrating them across all fields. Clinicians and researchers are now supporting various philosophies of component alignment and knee prosthesis biomechanics. This philosophy recognizes the uniqueness of each joint and supports a customized approach tailored to individual patients. Our ultimate goal is to improve the lifespan and functionality of arthroplasty, improve each patient's health-related quality of life, and achieve a sense of normalcy in the operated knee.

I would like to summarize the overall management of arthroplasty, which helps one overcome pain, swelling, and motor disorders caused by arthritis, leads one’s daily life, and maintains one’s health.

Topics to explore include:

  • Overall patient care in knee joint replacement;
  • Attention and development directions in surgery in knee joint replacement;
  • Clinical attention and management directions in knee joint replacement;
  • Defining the limits and disclosing future challenges.

We invite you all to be part of the most basic journey of this orthopedic surgery. Together, let us explore the front lines of knee arthroplasty to redefine the landscape of this field and improve the lives of patients.

Prof. Dr. Sang-Hoon Park
Guest Editor

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Keywords

  • knee surgery
  • knee arthroplasty
  • knee joint replacement
  • osteoarthritis
  • knee arthritis

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Published Papers (4 papers)

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Research

12 pages, 805 KB  
Article
Impact of Joint Line Displacement on Function and Quality of Life After Primary Total Knee Arthroplasty
by Eugenio Miguel Ferrer Santacreu, Sara López Resino, Yentl Garcelán Pecharromán and Pablo Cendrero Cendrero
J. Clin. Med. 2026, 15(10), 3737; https://doi.org/10.3390/jcm15103737 - 13 May 2026
Viewed by 314
Abstract
Background/Objectives: Total knee arthroplasty (TKA) is one of the most common surgeries among people over 60. Joint line restoration plays an important role in knee biomechanics, with joint line elevation or depression after TKA being associated with poorer postoperative outcomes, although there is [...] Read more.
Background/Objectives: Total knee arthroplasty (TKA) is one of the most common surgeries among people over 60. Joint line restoration plays an important role in knee biomechanics, with joint line elevation or depression after TKA being associated with poorer postoperative outcomes, although there is no consensus regarding the threshold at which these variations become clinically relevant. The objectives of this study were to evaluate whether a joint line variation greater than 4 mm after primary TKA affects postoperative outcomes, and to assess the concordance between different radiographic methods used to measure joint line height. Methods: A retrospective study was conducted including patients over 60 who underwent primary TKA for knee osteoarthritis. Joint line height variations were evaluated preoperatively and postoperatively using three radiographic measurements: lateral femoral epicondyle–fibular head (LEFH) distance, adductor tubercle–joint line (ATJL) distance, and Blackburne–Peel index. Quality of life was assessed using the Short Form-12 (SF-12) questionnaire, and functionality using the Knee Society Score (KSS). Statistical analysis was carried out using R software. Results: Seventy-three patients were included. No statistically significant associations were found between joint line displacement and functional outcomes (KSS), quality of life (SF-12), or postoperative complications. Concordance analysis between radiographic methods showed a significant but weak correlation between the LEFH and ATJL measurements (ρ = 0.419; p < 0.001). Conclusions: Joint line displacement after primary TKA was not associated with poorer postoperative outcomes in this cohort. These findings suggest that its clinical impact may depend more on its magnitude than on its mere presence and may also be influenced by additional factors. The weak concordance observed between radiographic measurement methods highlights the need for standardized criteria. Full article
(This article belongs to the Special Issue Clinical Management of Knee Arthroplasty)
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15 pages, 2841 KB  
Article
CAD-Based Analysis and Experimental Validation of Registration Errors in Imageless Total Knee Arthroplasty
by Muhammad Sohail, Salman Khalid, Muhammad Umar Elahi and Heung Soo Kim
J. Clin. Med. 2026, 15(6), 2335; https://doi.org/10.3390/jcm15062335 - 18 Mar 2026
Viewed by 333
Abstract
Background/Objectives: Accurate implant positioning in total knee arthroplasty (TKA) depends on reliable intraoperative landmark registration. In imageless TKA, registration errors can alter cutting-plane orientation and compromise alignment. This study quantitatively evaluated how anatomical landmark registration errors affect cutting-plane orientation in imageless TKA. [...] Read more.
Background/Objectives: Accurate implant positioning in total knee arthroplasty (TKA) depends on reliable intraoperative landmark registration. In imageless TKA, registration errors can alter cutting-plane orientation and compromise alignment. This study quantitatively evaluated how anatomical landmark registration errors affect cutting-plane orientation in imageless TKA. Methods: A CAD-based simulation with controlled experimental validation using 3D-printed bone models was performed to reproduce the imageless TKA workflow. Controlled errors were introduced into key femoral and tibial landmarks, and the resulting deviations were quantified. The primary evaluation metrics were angular deviations in varus/valgus, flexion/extension, and internal/external rotation. Results: Coronal and rotational alignment showed the greatest sensitivity to registration error. In the femur, anteroposterior epicondylar displacement had the strongest rotational influence, with sensitivity reaching about 0.5°/mm, whereas mediolateral displacement of the tibial anteroposterior landmarks showed the highest sensitivity at about 1.4°/mm. Similar trends were observed in both simulation and experimental validation cases. Conclusions: The findings indicate that small registration errors can produce clinically significant cutting-plane deviations in imageless TKA, particularly at the femoral transepicondylar and tibial anteroposterior landmarks, and may approach commonly accepted alignment thresholds. Full article
(This article belongs to the Special Issue Clinical Management of Knee Arthroplasty)
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10 pages, 201 KB  
Article
Is Concomitant Contralateral Arthroscopic Meniscectomy Effective in Patients Undergoing Unilateral Total Knee Replacement for Knee Osteoarthritis?
by Kee-Bum Hong, Han-Kook Yoon, Hyun-Cheol Oh, Seungyeon Kang and Sang-Hoon Park
J. Clin. Med. 2026, 15(1), 309; https://doi.org/10.3390/jcm15010309 - 31 Dec 2025
Cited by 3 | Viewed by 631
Abstract
Background/Objectives: In patients requiring unilateral total knee arthroplasty who have relatively mild but symptomatic degenerative osteoarthritis in the contralateral knee, there is ongoing debate regarding whether active intervention, such as arthroscopic surgery, should be performed concurrently or whether conservative management is more appropriate. [...] Read more.
Background/Objectives: In patients requiring unilateral total knee arthroplasty who have relatively mild but symptomatic degenerative osteoarthritis in the contralateral knee, there is ongoing debate regarding whether active intervention, such as arthroscopic surgery, should be performed concurrently or whether conservative management is more appropriate. This study compares patients who underwent simultaneous arthroscopic surgery on the contralateral knee with those who received only conservative treatment, and evaluates the effectiveness of performing arthroscopic surgery concurrently with total knee arthroplasty. Methods: From 2007 to 2013, 44 patients underwent unilateral total knee arthroplasty with simultaneous contralateral arthroscopic meniscectomy (Group 1), while 70 patients underwent unilateral total knee arthroplasty and received conservative treatment for degenerative osteoarthritis of the contralateral knee (Group 2). All patients were followed for a minimum of two years. Clinical outcomes were evaluated and compared using the Visual Analog Scale (VAS); Knee Society Score (KSS); and Lysholm score at preoperative, 1-month, 3-month, 1-year, and 2-year postoperative intervals. Results: At 1 and 3 months postoperatively, all outcome measures showed improvement compared to preoperative values, with Group 1 demonstrating significantly better results. At 1 and 2 years postoperatively, all three scores remained improved compared to preoperative levels but showed a declining trend relative to the early postoperative period, and no significant differences were observed between the two groups. Conclusions: In patients with degenerative osteoarthritis of the knee, simultaneous arthroscopic meniscectomy of the contralateral knee during unilateral total knee arthroplasty was associated with better early outcomes; however, no clinical or statistical differences were observed at 12 months. Full article
(This article belongs to the Special Issue Clinical Management of Knee Arthroplasty)
11 pages, 1772 KB  
Article
Mobile Versus Fixed-Bearing in Medial Unicompartmental Knee Arthroplasty: An Average 10-Year Follow-Up
by Sumin Lim, Tae Hun Kim, Do Young Park, Jung Sunwoo and Jun Young Chung
J. Clin. Med. 2025, 14(20), 7144; https://doi.org/10.3390/jcm14207144 - 10 Oct 2025
Cited by 1 | Viewed by 1675
Abstract
Background: Unicompartmental knee arthroplasty (UKA) represents a well-recognized treatment option for isolated medial compartment osteoarthritis; however, the debate regarding the superiority of fixed-bearing versus mobile-bearing designs continues. We aimed to evaluate the mid- to long-term outcomes of medial UKA comparing mobile- versus fixed-bearing [...] Read more.
Background: Unicompartmental knee arthroplasty (UKA) represents a well-recognized treatment option for isolated medial compartment osteoarthritis; however, the debate regarding the superiority of fixed-bearing versus mobile-bearing designs continues. We aimed to evaluate the mid- to long-term outcomes of medial UKA comparing mobile- versus fixed-bearing designs within a single institution over an average 10-year follow-up. Methods: This retrospective study included 81 consecutive patients who underwent primary medial UKA (45 fixed-bearing and 36 mobile-bearing) with a minimum five-year follow-up. Clinical outcomes were measured using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score and range of motion (ROM). Radiological measurements included hip-knee-ankle axis angle (HKA) and osteoarthritis progression. Implant survivorship was evaluated using Kaplan–Meier analysis, with failure defined as either conversion to total knee arthroplasty (TKA) or polyethylene (PE) exchange. Results: At a mean follow-up of 10.6 years, WOMAC scores, ROM, and radiological outcomes showed no statistically significant differences between the fixed-bearing and mobile-bearing groups. Significantly higher failure rates were observed in the mobile-bearing group, both when considering conversion only (p = 0.041) and when including conversion or PE exchange (p = 0.009). Survival analysis demonstrated 10-year rates of 97.8% for fixed-bearing and 88.9% for mobile-bearing with TKA conversion defined as failure (p = 0.066). Using combined failure criteria of TKA conversion or PE exchange, 10-year survival rates were 97.8% for fixed-bearing and 83.3% for mobile-bearing (p = 0.015). Conclusions: At a mean 10.6-year follow-up, clinical and radiological outcomes were comparable, but fixed-bearing UKA demonstrated superior survivorship. Full article
(This article belongs to the Special Issue Clinical Management of Knee Arthroplasty)
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