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Interventional Cardiology: Recent Advances and Future Perspectives

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 25 October 2025 | Viewed by 237

Special Issue Editors


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Guest Editor
Dipartimento di Scienze Cardiovascolari—CUORE, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy
Interests: structural intervention; acute heart failure; acute coronary syndrome
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Dipartimento di Scienze Cardiovascolari—CUORE, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy
Interests: acute heart failure; chronic heart failure; coronary intervention
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Interventional cardiology has rapidly evolved, offering innovative approaches to diagnosing and treating cardiovascular diseases. Recent advances in percutaneous coronary interventions (PCIs), structural heart interventions, and imaging technologies have significantly improved patient outcomes. The integration of artificial intelligence and novel biomaterials is further shaping the future of personalized cardiovascular care. Transcatheter therapies, including transcatheter aortic valve implantation (TAVI) and mitral valve repair, have expanded treatment options for high-risk patients. In addition, new pharmacological strategies and antithrombotic regimens are continuing to optimize procedural success and long-term safety. Despite these advancements, challenges remain in relation to patient selection, the long-term durability of devices, and managing complex coronary and structural heart disease. This Special Issue will explore the latest developments in interventional cardiology, emerging technologies, and future directions to enhance procedural efficacy and patient-centered care.

Dr. Cristina Aurigemma
Dr. Luigi Cappannoli
Guest Editors

Manuscript Submission Information

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Keywords

  • interventional cardiology
  • percutaneous coronary intervention (PCI)
  • transcatheter aortic valve implantation (TAVI)
  • structural heart disease
  • coronary artery disease
  • imaging and artificial intelligence
  • antithrombotic therapy
  • future technologies in cardiology
  • personalized cardiovascular care
  • minimally invasive interventions

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Published Papers (1 paper)

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Research

9 pages, 273 KiB  
Article
Suture or Device? A Real-World Analysis of the Closure Strategies in Patients Undergoing LAA Occlusion
by Saif Zako, Kathrin Klein, Asena Öz, Maei Elsobki, Philipp Mourikis, Carolin Helten, David Naguib, Malte Kelm, Tobias Zeus and Amin Polzin
J. Clin. Med. 2025, 14(15), 5245; https://doi.org/10.3390/jcm14155245 - 24 Jul 2025
Abstract
Background: Left atrial appendage occlusion (LAAO) is a valuable alternative to long-term anticoagulation in patients with atrial fibrillation (AF) and a high bleeding risk. However, effective vascular closure following large-bore venous access remains a clinical challenge, particularly in patients with multiple comorbidities. [...] Read more.
Background: Left atrial appendage occlusion (LAAO) is a valuable alternative to long-term anticoagulation in patients with atrial fibrillation (AF) and a high bleeding risk. However, effective vascular closure following large-bore venous access remains a clinical challenge, particularly in patients with multiple comorbidities. This study compares two venous closure techniques—Z-sutures and the suture-mediated ProGlide™ device—regarding their safety and efficacy in patients undergoing LAAO. Methods: We conducted a single-center observational study including 163 patients treated with LAAO between 2021 and 2024. Closure was achieved via a Z-suture (n = 126) or the ProGlide™ (n = 37) based on operator preference. The primary endpoint was clinically relevant bleeding (BARC ≥ 2). The secondary endpoints included 30-day mortality and hospital stay duration. Results: The Z-suture group included older and more comorbid patients. Despite these differences, the bleeding rates were comparable between groups. Clinically relevant bleeding was infrequent (Z-suture: 12.6%; ProGlide™: 13.5%). No 30-day deaths occurred in either group, and their hospital stay durations were similar. Conclusions: Both the Z-suture and ProGlide™ techniques demonstrated comparable safety and efficacy. Due to their simplicity and potential cost advantage, Z-sutures may be a practical alternative in routine care for high-risk patients. Full article
(This article belongs to the Special Issue Interventional Cardiology: Recent Advances and Future Perspectives)
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