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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Therapeutic Strategies in Rheumatic Diseases
edited by Răzvan Gabriel Drăgoi
submission deadline 25 Nov 2026 | 1 articles | Viewed by 719 | Submission Open
Keywords: rheumatic diseases; innovation; therapeutics; multidisciplinary; patient centered
(This special issue belongs to the Section Immunology & Rheumatology)
Clinical Management of Female Pelvic Floor Disorders
edited by and Stefano Salvatore
submission deadline 25 Nov 2026 | 1 articles | Viewed by 707 | Submission Open
Keywords: urinary incontinence; pelvic organ prolapse; pelvic floor disorders; pelvic reconstructive surgery; anal incontinence
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Advances and Emerging Trends in Metabolic Bariatric Surgery submission deadline 25 Nov 2026 | 1 articles | Viewed by 679 | Submission Open
Keywords: metabolic bariatric surgery; bariatric endoscopy; robotic assisted surgery; obesity management medications; bariatric surgery
(This special issue belongs to the Section General Surgery)
Clinical Advances in Management of Urologic Diseases
edited by Francesco Pio Bizzarri and Calogero Casà
submission deadline 25 Nov 2026 | 1 articles | Viewed by 671 | Submission Open
Keywords: prostate cancer; bladder cancer; kidney cancer; uro-oncology; radiotherapy
(This special issue belongs to the Section Nephrology & Urology)
Tinnitus: Clinical Updates from Diagnosis to Treatment
edited by
submission deadline 25 Nov 2026 | Viewed by 547 | Submission Open
Keywords: tinnitus related research; drug; cochlear implant or middle ear implant related tinnitus reduction
(This special issue belongs to the Section Otolaryngology)
Kidney Transplantation and Rehabilitation: Current Updates and Future Perspectives
edited by Zoltán Sándor
submission deadline 25 Nov 2026 | 1 articles | Viewed by 528 | Submission Open
Keywords: chronic kidney disease; kidney transplantation; transplant rehabilitation; transplant care; physical therapy; intervention; recovery; quality of life
(This special issue belongs to the Section Nephrology & Urology)
Bleeding Disorders and Hemophilia: Clinical Advances and Treatment submission deadline 25 Nov 2026 | 1 articles | Viewed by 520 | Submission Open
Keywords: hematology; hemophilia A and B; von willebrand disease (VWD); thrombocytopenia; thrombocytopathy; platelet function disorders; rare bleeding disorders (RBDs); coagulation factors; gene therapy; inhibitors; prophylaxis; clinical management; patient-reported outcomes
(This special issue belongs to the Section Hematology)
Spinal Cord Injury: New Horizons in Neurorehabilitation and Clinical Management
edited by Andrew Kerr and
submission deadline 25 Nov 2026 | Viewed by 312 | Submission Open
Keywords: spinal cord injury; rehabilitation; neuroplasticity; secondary health condition; neurological recovery; functional recovery; neuroprotection; neuroregeneration; neurotechnology
(This special issue belongs to the Section Clinical Neurology)
Clinical Progress in Diagnosis and Treatment of Pancreatic Cancer
edited by , Helwig Valentin Wundsam and
submission deadline 25 Nov 2026 | Viewed by 242 | Submission Open
Keywords: pancreatic ductal adenocarcinoma; early detection and biomarkers; multidisciplinary treatment strategies; complication management; liquid biopsy; surgical outcomes; translational clinical research
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Emerging Insights into Critical Care
edited by Shunsuke Takaki
submission deadline 25 Nov 2026 | Viewed by 238 | Submission Open
Keywords: critical care; intensive care unit; post-cardiac surgery; mechanical ventilation; clinical deterioration prediction; machine learning
(This special issue belongs to the Section Intensive Care)
Clinical Advances in Hypertension and Its Related Complications
edited by Antonio Concistrè
submission deadline 25 Nov 2026 | Viewed by 223 | Submission Open
Keywords: hypertension; secondary hypertension; resistant hypertension; blood pressure monitoring; target organ damage; cardiovascular risk; antihypertensive therapy; hypertension in pregnancy
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Applications of Ultrasound and Advanced Imaging Techniques in Thyroid Diseases
edited by and Andreea Bena
submission deadline 25 Nov 2026 | Viewed by 219 | Submission Open
Keywords: thyroid neoplasms; ultrasonography; elasticity imaging techniques; contrast media; thyroid MPUS; risk assessment; thyroid nodules; autoimmune thyroid disease
(This special issue belongs to the Section Endocrinology & Metabolism)
Innovations in Lumbar Spinal Surgery: Techniques, Outcomes, and Future Directions
edited by Shane Shahrestani and Andy Ton
submission deadline 25 Nov 2026 | Viewed by 213 | Submission Open
Keywords: lumbar spinal surgery; minimally invasive techniques; robotic-assisted surgery; spinal fusion; spinal implants
(This special issue belongs to the Section Orthopedics)
Clinical Advances and Prospects in Gynecologic Oncology Surgery submission deadline 25 Nov 2026 | Viewed by 213 | Submission Open
Keywords: gynecologic oncology; ERAS pathways; ERAS protocols; sentinel lymph node; laparoscopy; robotic surgery; molecular profiling; multidisciplinary team
(This special issue belongs to the Section Obstetrics & Gynecology)
Cerebral Palsy: Considerations for Clinical Practice
edited by Joav Merrick and
submission deadline 25 Nov 2026 | Viewed by 195 | Submission Open
Keywords: cerebral palsy; seizures; spasticity; feeding management; bowel and bladder incontinence
(This special issue belongs to the Section Clinical Neurology)
Otitis Media and Other Ear Disorders: Diagnosis and Management
edited by
submission deadline 25 Nov 2026 | Viewed by 185 | Submission Open
Keywords: otitis media; chronic otitis media; otitis media with effusion; cholesteatoma; tympanoplasty and mastoidectomy; hearing loss; tympanic membrane perforation; ear infection diagnosis; pediatric otology; conductive hearing loss
(This special issue belongs to the Section Otolaryngology)
Advances in Immunotherapy for Tumors: From Biomarkers to Novel Therapeutics and Exosome-Mediated Modulation submission deadline 25 Nov 2026 | Viewed by 180 | Submission Open
Keywords: immune checkpoint inhibitors; immunotherapy; exosomes; extracellular vesicles; tumor microenvironment; predictive biomarkers; liquid biopsy; immuno-oncology; precision medicine
(This special issue belongs to the Section Oncology)
Microsurgery: Current and Future Challenges, 2nd Edition submission deadline 25 Nov 2026 | Viewed by 161 | Submission Open
Keywords: microsurgery; reconstruction; reconstructive surgery; breast reconstruction; extremity reconstruction
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Beyond the Bench: Insights into Infectious Disease Epidemiology and Public Health
edited by Antonella Arghittu
submission deadline 25 Nov 2026 | Viewed by 160 | Submission Open
Keywords: antimicrobial resistance; infection prevention and control; one health; environmental monitoring; antimicrobial stewardship; surveillance; risk management; health communication; vaccine hesitancy
(This special issue belongs to the Section Epidemiology & Public Health)
Clinical Management and Revascularization of Coronary Artery Disease
edited by Simone Calcagno
submission deadline 25 Nov 2026 | Viewed by 140 | Submission Open
Keywords: coronary calcified lesion; IVUS; OCT; intravascular lithotripsy; bifurcation coronary lesions; chronic total occlusions; multivessel disease; STEMI; NSTEMI; coronary artery disease
(This special issue belongs to the Section Cardiovascular Medicine)
Advances in Sports-Related Orthopedic Injury and Surgery
edited by Paolo Schiavi and Francesco Pogliacomi
submission deadline 25 Nov 2026 | Viewed by 123 | Submission Open
Keywords: sports medicine; sport injury; sport surgery; sport trauma; performance; athletes; rapid recovery
(This special issue belongs to the Section Sports Medicine)
Colon and Rectal Surgery: Recent Advances and Future Trends
edited by Paraskevi Chatzikomnitsa and Alexandros E. Giakoustidis
submission deadline 26 Nov 2026 | Viewed by 255 | Submission Open
Keywords: colorectal surgery; minimally invasive surgery; robotic surgery; artificial intelligence in surgery; surgical innovation
(This special issue belongs to the Section General Surgery)
Novel Biomarkers and Treatment Strategies for Gastrointestinal Malignancies: From the Bench to the Bedside submission deadline 26 Nov 2026 | Viewed by 225 | Submission Open
Keywords: gastrointestinal (GI) malignancies; medical oncology; immunotherapy; biomarkers; target therapies
(This special issue belongs to the Section Oncology)
Life-Threatening Conditions in Pediatric Patients: Clinical Challenges and Emergency Management Strategies
edited by , Piotr Konrad Leszczyński, Alina Minarowska and
submission deadline 27 Nov 2026 | Viewed by 1240 | Submission Open
Keywords: child; pediatrics; pediatric emergencies; injuries; illnesses; clinical intervention; emergency treatment; acute care; life-threatening condition; therapeutic outcome
(This special issue belongs to the Section Emergency Medicine)
Rehabilitation Strategies for Neurological Disorders: Advances and Insights
edited by Delia Cinteză and Mihai Berteanu
submission deadline 30 Nov 2026 | 8 articles | Viewed by 15208 | Submission Open
Keywords: neurorehabilitation; physical medicine; virtual reality; AI in rehabilitation medicine; robotic rehabilitation; telerehabilitation; advanced technologies; upper neuromotor lesions; peripheral neuropathies; wearable sensor devices; assessment; goal-setting; individual rehabilitation plan
(This special issue belongs to the Section Clinical Rehabilitation)
Periodontal and Other Associated Oral Diseases: Diagnosis and Management in the Context of Systemic Pathology, 2nd Edition submission deadline 30 Nov 2026 | 4 articles | Viewed by 14216 | Submission Open
Keywords: periodontitis; oral diseases; periimplantitis; biomarkers; cytokines; oxidative stress markers; PCR test; point-of-care test; CBCT; periodontal treatment; immunomodulatory therapy; local drug delivery
(This special issue belongs to the Section Otolaryngology)
Reducing Modifiable Risk Factors to Prevent and Control Non-Communicable Diseases: 2nd Edition submission deadline 30 Nov 2026 | 4 articles | Viewed by 3061 | Submission Open
Keywords: non-communicable disease; chronic disease; cardiovascular disease; cancer; chronic respiratory disease; diabetes; mental health; tobacco use; physical inactivity; unhealthy diet; alcohol use; disease prevention
(This special issue belongs to the Section Epidemiology & Public Health)
Current Challenges and Updates in Therapeutic Advancements of Prostatectomy submission deadline 30 Nov 2026 | 2 articles | Viewed by 1376 | Submission Open
Keywords: radical prostatectomy; robot-assisted surgery; single port; artificial intelligence; complications; same day discharge; learning curve; training models; outcomes
(This special issue belongs to the Section Nephrology & Urology)
Metastatic Colorectal Cancer Beyond Second-Line Treatment
edited by Jacopo Giuliani
submission deadline 30 Nov 2026 | 1 articles | Viewed by 1219 | Submission Open
Keywords: metastatic colorectal cancer; subsequent lines; chemotherapy; targeted agents; radiotherapy; local therapy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Recent Advances in Clinical Therapeutic Methods of Kidney Stone submission deadline 30 Nov 2026 | 1 articles | Viewed by 1055 | Submission Open
Keywords: retrograde intrarenal surgery; ureteroscopy; percutaneous nephrolithotomy; laser lithotripsy; minimally invasive techniques
(This special issue belongs to the Section Nephrology & Urology)
From Imaging to Impact: Improving Breast Cancer Diagnosis and Outcomes
edited by Dana Samir Al-Mousa and Kelly Bentley-Spuur
submission deadline 30 Nov 2026 | 1 articles | Viewed by 811 | Submission Open
Keywords: breast cancer diagnosis; breast imaging; breast cancer screening; screening mammography; diagnostic breast imag-ing; breast density assessment; early detection of breast cancer; breast imaging innovation; diagnostic accuracy in breast imaging; artificial intelligence in breast imaging; radiation dose optimisation in breast imaging; image quality in breast imaging; clinical implementation of breast imaging technologies; patient outcomes in breast cancer care; health system efficiency in breast imaging
(This special issue belongs to the Section Nuclear Medicine & Radiology)
New Insights into Sports Injuries and Rehabilitation: From Injury to Performance submission deadline 30 Nov 2026 | 1 articles | Viewed by 766 | Submission Open
Keywords: sports medicine; sports injuries; orthopedic rehabilitation; upper limb injuries; tendon and ligament injuries; return to sport; injury prevention; regenerative therapies
(This special issue belongs to the Section Sports Medicine)
Interventional Treatment of Coronary Artery Disease: Clinical Insights and Current Practice
edited by
submission deadline 30 Nov 2026 | 1 articles | Viewed by 579 | Submission Open
Keywords: percutaneous coronary intervention (PCI); coronary artery disease (CAD); complex coronary intervention; physiology-guided revascularization (FFR/iFR); post-PCI Integrated non-pharmacological therapies; intravascular imaging (IVUS/OCT); severe coronary calcification; personalized antiplatelet therapy; spontaneous coronary artery dissection; high bleeding risk; drug-coated balloons; artificial intelligence in interventional cardiology
(This special issue belongs to the Section Cardiology)
Current Advances and Future Perspectives in Cardiothoracic Surgery
edited by Tomislav Kopjar
submission deadline 30 Nov 2026 | 1 articles | Viewed by 473 | Submission Open
Keywords: cardiothoracic surgery; minimally invasive techniques; robotic-assisted surgery; personalized therapy; surgical innovation; prosthetic devices; perioperative management; transplantation; technological advances; postoperative care; surgical outcomes; future perspectives; healthcare disparities
(This special issue belongs to the Section General Surgery)
Cruciate Ligament Injuries in Sport Medicines: Diagnosis, Treatment and Rehabilitation
edited by
submission deadline 30 Nov 2026 | Viewed by 287 | Submission Open
Keywords: cruciate ligament; sport medicine; trauma; meniscus; knee instability; anterior cruciate ligament reconstruction; posterior cruciate ligament; rehabilitation; return to sport; injury prevention
(This special issue belongs to the Section Sports Medicine)
The Use of Artificial Intelligence in Cancer Research, Diagnosis, and Care
edited by
submission deadline 30 Nov 2026 | Viewed by 242 | Submission Open
Keywords: artificial intelligence; oncology; cancer diagnosis; prognostic modeling; clinical validation; digital twins
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Clinical Medicine)
Targeted Management and Diagnosis of Rheumatoid Arthritis submission deadline 30 Nov 2026 | Viewed by 182 | Submission Open
Keywords: rheumatoid arthritis; difficult-to-treat rheumatoid arthritis; erosive arthritis; JAK inhibitors; biological drugs; window-of-opportunity
(This special issue belongs to the Section Immunology & Rheumatology)
Sjogren’s Syndrome: Clinical Advances and Insights
edited by David A. Isenberg
submission deadline 7 Dec 2026 | 9 articles | Viewed by 14672 | Submission Open
Keywords: xerostomia; xerophthalmia; non-Hodgkins lymphoma; autoimmune rheumatic diseases; Sjogren’s syndrome
(This special issue belongs to the Section Immunology & Rheumatology)
Placental Dysfunction and Cardiovascular Maternal Risk-Timing Assessment and Postpartum Challenges
edited by , Anca Huniadi and
submission deadline 8 Dec 2026 | Viewed by 276 | Submission Open
Keywords: cardiovascular risk; pre-eclampsia; fetal growth restriction; placental dysfunction; cardiac function; biomarkers
(This special issue belongs to the Section Obstetrics & Gynecology)
The Role of Cardiac Rehabilitation After Myocardial Infarction, Coronary Artery Bypass Surgery, and in Other Cardiac Diseases
edited by
submission deadline 10 Dec 2026 | 4 articles | Viewed by 12660 | Submission Open
Keywords: cardiac rehabilitation; coronary artery disease; myocardial infarction; coronary artery bypass surgery; heart failure; ventricular assist device; heart transplantation; cardiomyopathies; cardiac remodeling; illness perception; treatment adherence; gender difference; biomarkers; endothelial function
(This special issue belongs to the Section Cardiology)
Regional Anesthesia and Pain Management: Mastering Clinical Art for Optimal Patient Satisfaction
edited by
submission deadline 10 Dec 2026 | 8 articles | Viewed by 7992 | Submission Open
Keywords: regional anesthesia; pain management; ultrasound-guided nerve blocks; fascial plane blocks; multimodal analgesia; postoperative analgesia; chronic pain management; opioid-sparing strategies; non-opioid analgesics; patient satisfaction; anesthesia techniques; perioperative care; pain interventions; nerve block techniques; clinical outcomes
(This special issue belongs to the Section Anesthesiology)
New Clinical Advances in Pediatric Asthma
edited by
submission deadline 10 Dec 2026 | 3 articles | Viewed by 3835 | Submission Open
Keywords: pediatric asthma; clinical management; treatment advances; diagnostic advances; biologic therapy; inhaled steroids; control of asthma; exacerbation prevention; quality of life
(This special issue belongs to the Section Clinical Pediatrics)
Prevention and Management of Sexual Dysfunction submission deadline 10 Dec 2026 | 3 articles | Viewed by 2704 | Submission Open
Keywords: sexual health; sexual dysfunction; reproductive health; general sexuology; sexological care
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Translational Immunology in Clinical Medicine: From Preclinical Insights to Therapeutic Impact
edited by
submission deadline 10 Dec 2026 | 1 articles | Viewed by 2017 | Submission Open
Keywords: translational immunology; autoimmune disease; autoinflammatory disease; immune-mediated diseases; oncology; preclinical models; immune efficacy and safety; mechanism of action; immunotoxicity assessment
(This special issue belongs to the Section Immunology & Rheumatology)
Obstructive Sleep Apnea: Advances and Challenges in Diagnosis, Phenotyping, and Clinical Impact
edited by , Muna Irfan and Andrew Namen
submission deadline 10 Dec 2026 | 3 articles | Viewed by 1783 | Submission Open
Keywords: obstructive sleep apnea; sleep diagnostics; screening tools; pulse oximetry; polysomnography; home sleep apnea testing; diagnostic accuracy; phenotyping; cardiometabolic comorbidity; neuropsychiatric outcomes; sleep -disordered breathing; real-world implementation
(This special issue belongs to the Section Respiratory Medicine)
Breaking Barriers in Respiratory Conditions: From Clinical Pathophysiology to Treatment Across the Spectrum of Severity
edited by
submission deadline 10 Dec 2026 | 1 articles | Viewed by 1199 | Submission Open
Keywords: pulmonary rehabilitation; skeletal muscle; exercise physiology; exercise intolerance; physical activity; respiratory conditions
(This special issue belongs to the Section Respiratory Medicine)
Clinical Rehabilitation and Management of Chronic Musculoskeletal Pain Conditions
edited by
submission deadline 10 Dec 2026 | 2 articles | Viewed by 622 | Submission Open
Keywords: reproducibility of results; rehabilitation; physical therapy; artificial intelligence; machine learning; musculoskeletal system; treatment outcome
(This special issue belongs to the Section Clinical Rehabilitation)
Cesarean Section Versus Vaginal Delivery submission deadline 10 Dec 2026 | Viewed by 526 | Submission Open
Keywords: cesarean section; vaginal delivery; birth outcomes; birth complications; delivery mode; labor process; obstetric care; trial of labor after cesarean (TOLAC); intrapartum care; obstetric decision-making
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in Cosmetic Dermatology: From Health to Aesthetics and Restoring Confidence
edited by
submission deadline 10 Dec 2026 | 1 articles | Viewed by 513 | Submission Open
Keywords: aesthetic dermatology; cosmetic dermatology; energy-based devices; dermal fillers; botulinum toxin; biostimulators; skin rejuvenation; regenerative medicine; scar treatment; hair disorders; pigmentary disorders
(This special issue belongs to the Section Dermatology)
The Current Trend in the Management of Bruxism and Temporomandibular Disorders, 2nd Edition submission deadline 10 Dec 2026 | Viewed by 436 | Submission Open
Keywords: bruxism; temporomandibular disorders (TMDs); dental health; treatment modalities; diagnosis; clinical interventions
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
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